NANO Isothermal Titration Calorimetry

"Overview
There are three ways in which a calorimeter may be designed. Heat measurements
may be based on the following:
• a temperature rise measured in a system of known heat capacity, (ΔT)
• the measured change in power (typically resistance heating) required to maintain
a system at a constant temperature (power compensation); and
• a direct measure of the heat flowing between the system and large heat sink
maintained at a constant temperature (heat flow).
Each method (ΔT, power compensation, and heat flow) has its advantages and
disadvantages. The TA Instruments Nano Isothermal Titration Calorimeter (ITC)
uses a differential power compensation design for maximum sensitivity and
responsiveness."