Center of Infectious Disease and Signaling Research

Organization profile

Organisation profile

Center of Infectious Disease and Signaling Research (CIDSR) The rapid spread of emerging infectious agents has summoned urgently with capacity building to counteract the invasion. To achieve effective prevention and mitigate the threat of citizens in Taiwan, Center of Infectious Disease and Signaling Research (CIDSR) is established by integrating the outstanding NCKU research groups into one roof center. The CIDSR has actively engaged with International Institutes to form a scholar platform offering to cultivate and identify talented individual interesting in the subject. The mission of CIDSR is to institute innovative research within a specific topic and to improve quality of patient cares.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Neoplasms Medicine & Life Sciences
Cells Chemical Compounds
Tubulin Medicine & Life Sciences
KB Cells Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Antineoplastic Agents Medicine & Life Sciences
Microtubules Medicine & Life Sciences
Inhibitory Concentration 50 Medicine & Life Sciences

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Research Output 1989 2019

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J-Y. & Liou, J. P., 2019 Jan 15, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Inhibitory Concentration 50

Alpha-tubulin acetyltransferase/MEC-17 regulates cancer cell migration and invasion through epithelial–mesenchymal transition suppression and cell polarity disruption

Lee, C. C., Cheng, Y. C., Chang, C. Y., Lin, C. M. & Chang, J-Y., 2018 Dec 1, In : Scientific Reports. 8, 1, 17477.

Research output: Contribution to journalArticle

Cell Polarity
Cell Movement

Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition (Org. Biomol. Chem. (2016) 14 (716-723))

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J-Y., Liou, J. P. & Lee, H. Y., 2018 Jan 1, In : Organic and Biomolecular Chemistry. 16, 25, 1 p.

Research output: Contribution to journalComment/debate

HSP90 Heat-Shock Proteins
Antineoplastic Agents