Research Output 1973 2019

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1973
4 Citations (Scopus)

The Binding of Abrin and Ricin by Ehrlich Ascites Tumor Cells

Lin, J. Y., Ju, S. T., Wu, H-L. & Tung, T. C., 1973 Jan 1, In : Cancer Research. 33, 11, p. 2688-2691 4 p.

Research output: Contribution to journalArticle

Abrin
Ricin
Ehrlich Tumor Carcinoma
Galactose
Poisons
1974
35 Citations (Scopus)

Cardiotoxic protein from edible mushrooms

Lin, J. Y., Lin, Y. J., Chen, C. C., Wu, H-L., Shi, G. Y. & Jeng, T. W., 1974 Dec 1, In : Nature. 252, 5480, p. 235-237 3 p.

Research output: Contribution to journalArticle

Agaricales
Volvariella
Flammulina
Proteins
1975
22 Citations (Scopus)

Toxicity of the cardiotoxic protein, flammutoxin, isolated from the edible mushroom Flammunlina velutipes

Lin, J. Y., Wu, H-L. & Shi, G. Y., 1975 Jan 1, In : Toxicon. 13, 5, p. 323-326 4 p.

Research output: Contribution to journalArticle

Agaricales
Toxicity
Poisons
Proteins
Flammulina
1978
Sex Determination Analysis
Sex Chromosomes
Cheek
Y Chromosome
Mouth Mucosa
1979
69 Citations (Scopus)
Isoflurophate
Serum Albumin
Tyrosine
Ionic strength
Osmolar Concentration
1981
24 Citations (Scopus)

Disruption of the tryptophan binding site in the human serum albumin dimer

Sollenne, N. P., Wu, H. L. & Means, G. E., 1981 Apr 1, In : Archives of Biochemistry and Biophysics. 207, 2, p. 264-269 6 p.

Research output: Contribution to journalArticle

Serum Albumin
Tryptophan
Dimers
Charcoal
Binding Sites
19 Citations (Scopus)

Immobilization of proteins by reductive alkylation with hydrophobic aldehydes

Wu, HL. L. & Means, G. E., 1981 Apr, In : Biotechnology and Bioengineering. 23, 4, p. 855-861 7 p.

Research output: Contribution to journalArticle

Alkylation
Aldehydes
Immobilization
Gels
Enzymes
1982
24 Citations (Scopus)

Role of Aromatic Residues in the Structure-Function Relationship of α-Bungarotoxin

Chen, Y. H., Tai, J. C., Huang, W. J., Lai, M. Z., Hung, M. C., Lai, M. D. & Yang, J. T., 1982 May, In : Biochemistry. 21, 11, p. 2592-2600 9 p.

Research output: Contribution to journalArticle

Bungarotoxins
Circular Dichroism
Tyrosine
Conformations
Derivatives
6 Citations (Scopus)

The denaturation of trypsin

Wu, H. L., Kundrot, C. & Bender, M. L., 1982 Jul 30, In : Biochemical and Biophysical Research Communications. 107, 2, p. 742-745 4 p.

Research output: Contribution to journalArticle

Denaturation
Trypsin
Ions
Calcium
Chymotrypsin
1987
45 Citations (Scopus)

Preparation and purification of microplasmin.

Wu, H-L., Shi, G. Y. & Bender, M. L., 1987 Jan 1, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 23, p. 8292-8295 4 p.

Research output: Contribution to journalArticle

Fibrinolysin
valyl-leucyl-lysine 4-nitroanilide
Molecular Weight
Trypsin Inhibitors
Affinity Chromatography
47 Citations (Scopus)

Structure and formation of microplasmin.

Wu, H-L., Shi, G. Y., Wohl, R. C. & Bender, M. L., 1987 Jan 1, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 24, p. 8793-8795 3 p.

Research output: Contribution to journalArticle

Fibrinolysin
Peptides
Disulfides
Amino Acids
Autolysis
1988
Microcomputers
Software packages
Personal computers
Stars
Software

Cloning of a LEU gene and an ARS site of Rhodotorula glutinis

Ho, Y-R. & Chang, M. C., 1988 Jan 1, In : Chinese Journal of Microbiology and Immunology. 21, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Fungal DNA
Fungal Genes
Mitosporic Fungi
Rhodotorula
Nucleic Acid Hybridization
8 Citations (Scopus)

Differential autolysis of human plasmin at various pH levels

Shi, G. Y. & Wu, H. L., 1988 Aug 15, In : Thrombosis Research. 51, 4, p. 355-364 10 p.

Research output: Contribution to journalArticle

Autolysis
Fibrinolysin
Light
Esterases
Molecular Weight
3 Citations (Scopus)
DNA Polymerase I
Metals
Escherichia coli
DNA Primers
DNA
16 Citations (Scopus)

Influence of DNA Sequence on the Nature of Mispairing during DNA Synthesis

Lai, M-D. & Beattie, K. L., 1988 Mar 1, In : Biochemistry. 27, 5, p. 1722-1728 7 p.

Research output: Contribution to journalArticle

DNA sequences
DNA-Directed DNA Polymerase
Substitution reactions
Murine Leukemia Viruses
DNA Polymerase I
67 Citations (Scopus)

Isolation and characterization of microplasminogen. A low molecular weight form of plasminogen

Shi, G. Y. & Wu, H-L., 1988 Jan 1, In : Journal of Biological Chemistry. 263, 32, p. 17071-17076 6 p.

Research output: Contribution to journalArticle

Plasminogen
Molecular Weight
Molecular weight
Fibrinolysin
Urokinase-Type Plasminogen Activator
17 Citations (Scopus)

Resonance Raman spectra of bovine liver catalase: Enhancement of proximal tyrosinate vibrations

Chuang, W. J., Johnson, S. & Van Wart, H. E., 1988 Nov, In : Journal of Inorganic Biochemistry. 34, 3, p. 201-219 19 p.

Research output: Contribution to journalArticle

Porphyrins
Vibration
Liver
Catalase
Vibrations (mechanical)
4 Citations (Scopus)

The effect of thymosin on experimental herpes simplex virus infections

Shiau, A-L., Wu, C-L. & Huang, K. Y., 1988 Jan 1, In : Journal of the Formosan Medical Association. 87, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

Thymosin
Species Specificity
Herpes Simplex
Inbred Strains Mice
Virus Diseases
1989
37 Citations (Scopus)

Resonance raman spectra of bovine liver catalase compound II. Similarity of the heme environment to horseradish peroxidase compound II

Chuang, W. J., Heldt, J. & Van Wart, H. E., 1989 Jan 1, In : Journal of Biological Chemistry. 264, 24, p. 14209-14215 7 p.

Research output: Contribution to journalArticle

Horseradish Peroxidase
Heme
Liver
Catalase
Raman scattering

Single-step selection of mammalian cell mutants deficient in CTP synthetase

Li, I. C., Wu, C. L. & Chu, E. H. Y., 1989 Jan 1, In : Somatic Cell and Molecular Genetics. 15, 1, p. 85-91 7 p.

Research output: Contribution to journalArticle

CTP synthetase
Cytidine
Uridine
Thymidine
Cytidine Triphosphate
1990
12 Citations (Scopus)

Activation of human and bovine plasminogens by the microplasmin and streptokinase complex

Shi, G. Y., Chang, B. I., Wu, D. H., Ha, Y. M. & Wu, H-L., 1990 May 1, In : Thrombosis Research. 58, 3, p. 317-329 13 p.

Research output: Contribution to journalArticle

Streptokinase
Fibrinolysin
Plasminogen
Population Groups
Human Activities
62 Citations (Scopus)

Interaction of plasminogen and fibrin in plasminogen activation

Wu, H. L., Chang, B. I., Wu, D. H., Chang, L. C., Gong, C. C., Lou, K. L. & Shi, G. Y., 1990 Dec 17, In : Journal of Biological Chemistry. 265, 32, p. 19658-19664 7 p.

Research output: Contribution to journalArticle

Kringles
Plasminogen
Fibrin
Chemical activation
Fibrinogen
3 Citations (Scopus)

Isolation of rat renal NAD+-dependent 15-hydroxyprostaglandin dehydrogenase

Chang, W. C., Wu, H. L., Hsu, S. Y. & Chen, F. S., 1990 Sep, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 41, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

15-hydroxyprostaglandin dehydrogenase
Rats
Kidney
Enzymes
Column chromatography
1991
41 Citations (Scopus)

Cytoprotective effect of reduced glutathione in arsenical-induced endothelial cell injury

Chang, W. C., Chen, S-H., Wu, H-L., Shi, G. Y., Murota, S. I. & Morita, I., 1991 Jan 1, In : Toxicology. 69, 1, p. 101-110 10 p.

Research output: Contribution to journalArticle

Arsenicals
Endothelial cells
Glutathione
Endothelial Cells
Biosynthesis
3 Citations (Scopus)

Kringle domains and plasmin denaturation

Shi, G. Y., Wu, D. H. & Wu, H. L., 1991 Jul 15, In : Biochemical and Biophysical Research Communications. 178, 1, p. 360-368 9 p.

Research output: Contribution to journalArticle

Kringles
Denaturation
Fibrinolysin
Fibrinogen
Degradation
23 Citations (Scopus)

The effects of glucocorticoid hormone on the expression of c-jun

Lee, H., Shaw, Y. T., Chiou, S. T., Chang, W. C. & Lai, M. D., 1991 Mar 11, In : FEBS Letters. 280, 1, p. 134-136 3 p.

Research output: Contribution to journalArticle

Fibroblasts
Cycloheximide
Dexamethasone
Glucocorticoids
Hormones
1992
11 Citations (Scopus)

Cytoprotective effect of reduced glutathione in hydrogen peroxide-induced endothelial cell injury

Chen, S-H., Wu, H-L., Lin, M. T., Jen, C. J., Wing, L. Y. C., Lei, H. Y., Tsao, C. J. & Chang, W. C., 1992 Jan 1, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 45, 4, p. 299-305 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Epoprostenol
Hydrogen Peroxide
Glutathione
Endothelial Cells
185 Citations (Scopus)

Detection of HCV RNA in saliva, urine, seminal fluid, and ascites

Liou, TC. C., Chang, T-T., Young, K-C., Lin, X-Z., Lin, CY. Y. & Wu, H-L., 1992 Jan 1, In : Journal of Medical Virology. 37, 3, p. 197-202 6 p.

Research output: Contribution to journalArticle

Saliva
Ascites
Hepacivirus
Urine
RNA
6 Citations (Scopus)

Neonatal screening for alpha-thalassemia in southern Taiwan.

Lin, T. M., Eng, H. L., Kuo, P-L. & Wu, H-L., 1992 Jan 1, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 91, 12, p. 1213-1215 3 p.

Research output: Contribution to journalArticle

alpha-Thalassemia
Neonatal Screening
Taiwan
Fetal Blood
Gene Deletion
28 Citations (Scopus)

Plasmin and the regulation of tissue-type plasminogen activator biosynthesis in human endothelial cells

Shi, G. Y., Hau, J. S., Wang, S. J., Wu, I. S., Chang, B. I., Lin, M. T., Chow -, Y. H., Chang, W. C., Wing, L. Y. C., Jen, C. J. & Wu, H-L., 1992 Jan 1, In : Journal of Biological Chemistry. 267, 27, p. 19363-19368 6 p.

Research output: Contribution to journalArticle

Plasminogen Activators
Fibrinolysin
Biosynthesis
Endothelial cells
Human Umbilical Vein Endothelial Cells
60 Citations (Scopus)
Horseradish Peroxidase
Liver
Catalase
Ground state
Cations
22 Citations (Scopus)

The binding of plasminogen fragments to cultured human umbilical vein endothelial cells

Wu, H-L., Wu, I. S., Fang, R. Y., Hau, J. S., Wu, D. H., Cheng, B. I., Lin, T. M. & Shi, G. Y., 1992 Oct 30, In : Biochemical and Biophysical Research Communications. 188, 2, p. 703-711 9 p.

Research output: Contribution to journalArticle

Kringles
Plasminogen
Endothelial cells
Human Umbilical Vein Endothelial Cells
Binding Sites
16 Citations (Scopus)

Two-Dimensional NMR, Circular Dichroism, and Fluorescence Studies of PP-50, a Synthetic ATP-Binding Peptide from the π-Subunit of Mitochondrial ATP Synthase

Chuang, W. J., Abeygunawardana, C., Pedersen, P. L. & Mildvan, A. S., 1992 Feb 1, In : Biochemistry. 31, 34, p. 7915-7921 7 p.

Research output: Contribution to journalArticle

Mitochondrial Proton-Translocating ATPases
Circular Dichroism
Adenosine Triphosphate
Ionic strength
Fluorescence
1993
72 Citations (Scopus)

Detection of hepatitis C virus RNA in peripheral blood mononuclear cells and in saliva

Young, KC. C., Chang, TT. T., Liou, TC. C. & Wu, HL. L., 1993 Sep, In : Journal of Medical Virology. 41, 1, p. 55-60 6 p.

Research output: Contribution to journalArticle

Saliva
Hepacivirus
Blood Cells
RNA
Chronic Hepatitis C
36 Citations (Scopus)

Hepatitis B and hepatitis C among institutionalized psychiatric patients in Taiwan

Chang, TT. T., Lin, H., Yen, YS. S. & Wu, HL. L., 1993 Jun, In : Journal of Medical Virology. 40, 2, p. 170-173 4 p.

Research output: Contribution to journalArticle

Hepatitis C
Hepatitis B
Taiwan
Psychiatry
Hepatitis C Antibodies
51 Citations (Scopus)

Human plasmin induces a receptor-mediated arachidonate release coupled with G proteins in endothelial cells

Chang, W. C., Shi, G. Y., Chow, Y. H., Chang, L. C., Hau, J. S., Lin, M. T., Jen, C. J., Wing, L. Y. C. & Wu, H-L., 1993 Jan 1, In : American Journal of Physiology - Cell Physiology. 264, 2 33-2

Research output: Contribution to journalArticle

Fibrinolysin
GTP-Binding Proteins
Endothelial Cells
Pertussis Toxin
Tranexamic Acid
12 Citations (Scopus)

Impaired fibrinolysis in patients with blackfoot disease

Wu, H-L., Yang, W-H., Wang, M. Y. & Shi, G. Y., 1993 Nov 1, In : Thrombosis Research. 72, 3, p. 211-218 8 p.

Research output: Contribution to journalArticle

Fibrinolysis
Plasminogen Activators
Urokinase-Type Plasminogen Activator
von Willebrand Factor
Tissue Plasminogen Activator
6 Citations (Scopus)

Interaction of immobilized human plasminogen and plasmin with streptokinase

Shi, G. Y., Chang, B. I., Wu, D. H. & Wu, H-L., 1993 Aug 31, In : Biochemical and Biophysical Research Communications. 195, 1, p. 192-200 9 p.

Research output: Contribution to journalArticle

Streptokinase
Plasminogen
Fibrinolysin
valyl-leucyl-lysine 4-nitroanilide
Urokinase-Type Plasminogen Activator
178 Citations (Scopus)

Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6

Wang, SL. L., Huang, JD. D., Lai, M-D., Liu, BH. H. & Lai, ML. L., 1993 Jan 1, In : Clinical Pharmacology & Therapeutics. 53, 4, p. 410-418 9 p.

Research output: Contribution to journalArticle

Debrisoquin
Cytochrome P-450 CYP2D6
Hydroxylation
Restriction Fragment Length Polymorphisms
Molecular Biology
4 Citations (Scopus)

Mutational tests of the NMR‐docked structure of the staphylococcal nuclease–metal–3′,5′‐pdTp complex

Chuang, WJ. J., Weber, D. J., Gittis, A. G. & Mildvan, A. S., 1993 Sep, In : Proteins: Structure, Function, and Bioinformatics. 17, 1, p. 36-48 13 p.

Research output: Contribution to journalArticle

X-Rays
Micrococcal Nuclease
Enzymes
Mutation
4 alpha-glucanotransferase
5 Citations (Scopus)

Partial reversion of transformed phenotype of B104 cancer cells by antisense nucleic acids

Shaw, Y. T., Chang, S. H., Chiou, S. T., Chang, W. C. & Lai, M. D., 1993 Apr 15, In : Cancer Letters. 69, 1, p. 27-32 6 p.

Research output: Contribution to journalArticle

Nucleic Acids
Phenotype
Oncogenes
Antisense RNA
Neoplasms
72 Citations (Scopus)

Production of a model for Lesch–Nyhan syndrome in hypoxanthine phosphoribosyltransferase–deficient mice

Wu, C. L. & Melton, D. W., 1993 Mar, In : Nature Genetics. 3, 3, p. 235-240 6 p.

Research output: Contribution to journalArticle

Hypoxanthine
Adenine Phosphoribosyltransferase
Lesch-Nyhan Syndrome
Hypoxanthine Phosphoribosyltransferase
Genetic Models
10 Citations (Scopus)

Release of the p53-induced repression on thymidine kinase promoter by single p53-binding sequence

Yuan, J. N., Liu, B. H., Lee, H., Shaw, Y. T., Chiou, S. T., Chang, W. C. & Lai, M. D., 1993 Mar 15, In : Biochemical and Biophysical Research Communications. 191, 2, p. 662-668 7 p.

Research output: Contribution to journalArticle

Thymidine Kinase
Binding Sites
Herpes Simplex
Gene expression
Gene Expression
1994
5 Citations (Scopus)

Carrier screening and prenatal diagnosis for alpha-thalassemia with biphasic polymerase chain reaction.

Kuo, P-L., Lin, T. M., Huang, K. F., Yeh, N. G., Wu, D. B., Wu, R. C., Tzeng, C. C., Wu, H-L. & Huang, K. E., 1994 Jan 1, In : Journal of the Formosan Medical Association = Taiwan yi zhi. 93, 9, p. 765-769 5 p.

Research output: Contribution to journalArticle

alpha-Thalassemia
Prenatal Diagnosis
Southeastern Asia
Polymerase Chain Reaction
Hydrops Fetalis
78 Citations (Scopus)

Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene

Chang, M-S., McNinch, J., Basu, R. & Simonet, S., 1994 Oct 14, In : Journal of Biological Chemistry. 269, 41, p. 25277-25282 6 p.

Research output: Contribution to journalArticle

Cloning
Organism Cloning
Neutrophils
Genes
Interleukin-8
1 Citation (Scopus)

Diacylglycerol formation induced by human plasmin in cultured endothelial cells

Chang, W. C., Shi, G. Y., Lin, M. T., Jen, C. J., Wing, L. Y. C. & Wu, H. L., 1994 Oct 1, In : Thrombosis Research. 76, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

Fibrinolysin
Diglycerides
Cultured Cells
Endothelial Cells
Palmitates
57 Citations (Scopus)

Function of streptokinase fragments in plasminogen activation

Shi, G. Y., Chang -i., B., Chen, S. M., Wu, D. H. & Wu, H-L., 1994 Jan 1, In : Biochemical Journal. 304, 1, p. 235-241 7 p.

Research output: Contribution to journalArticle

Streptokinase
Plasminogen
Chemical activation
Peptide Fragments
Fibrinolysin
818 Citations (Scopus)

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MpI

Bartley, T. D., Bogenberger, J., Hunt, P., Li, Y. S., Lu, H. S., Martin, F., Chang, M-S., Samal, B., Nichol, J. L., Swift, S., Johnson, M. J., Hsu, R. Y., Parker, V. P., Suggs, S., Skrine, J. D., Merewether, L. A., Clogston, C., Hsu, E., Hokom, M. M., Hornkohl, A. & 33 others, Choi, E., Pangelinan, M., Sun, Y., Mar, V., McNinch, J., Simonet, L., Jacobsen, F., Xie, C., Shutter, J., Chute, H., Basu, R., Selander, L., Trollinger, D., Sieu, L., Padilla, D., Trail, G., Elliott, G., Izumi, R., Covey, T., Crouse, J., Garcia, A., Xu, W., Del Castillo, J., Biron, J., Cole, S., Hu, M. C. T., Pacifici, R., Ponting, I., Saris, C., Wen, D., Yung, Y. P., Lin, H. & Rosselman, R. A., 1994 Jul 1, In : Cell. 77, 7, p. 1117-1124 8 p.

Research output: Contribution to journalArticle

Thrombopoietin
Cytokine Receptors
Cloning
Organism Cloning
Ligands
75 Citations (Scopus)

Intrafamilial transmission of hepatitis C virus: The important role of inapparent transmission

Chang, T-T., Liou, TC. C., Young, K-C., Lin, X-Z., Lin, CY. Y., Shin, JS. S. & Wu, H-L., 1994 Jan 1, In : Journal of Medical Virology. 42, 1, p. 91-96 6 p.

Research output: Contribution to journalArticle

Hepacivirus
Virus Diseases
Odds Ratio
Immunosorbents
Spouses