Research Output 1973 2019

Filter
Article

[Prothymosin alpha interacts with C-terminal domain of histone H1 and dissociates p53-histone H1 complex].

Zakharova, N. I., Sokolov, V. V., Suvorova, A. A., Shiau, A. I., Wu, C. L. & Efstaf'eva, A. G., 2011 Jul 1, In : Molekuliarnaia biologiia. 45, 4, p. 679-688 10 p.

Research output: Contribution to journalArticle

Histones
prothymosin alpha
Tumor Suppressor Protein p53
p53 Genes
Nuclear Proteins
16 Citations (Scopus)

2DCSi: Identification of protein secondary structure and redox state using 2D cluster analysis of NMR chemical shifts

Wang, C. C., Chen, J. H., Lai, W. C. & Chuang, W. J., 2007 May 1, In : Journal of Biomolecular NMR. 38, 1, p. 57-63 7 p.

Research output: Contribution to journalArticle

Secondary Protein Structure
Cluster analysis
Chemical shift
Oxidation-Reduction
Cluster Analysis
38 Citations (Scopus)

Aberrant cyclin a expression and centrosome overduplication induced by hepatitis B virus pre-S2 mutants and its implication in hepatocarcinogenesis

Wang, L. H. C., Huang, W., Lai, M. D. & Su, I. J., 2012 Feb 8, In : Carcinogenesis. 33, 2, p. 466-472 7 p.

Research output: Contribution to journalArticle

Cyclin A
Centrosome
Cyclins
Hepatitis B virus
Endoplasmic Reticulum Stress
33 Citations (Scopus)

Aberrant Prothymosin-alpha Expression in Human Bladder Cancer

Tsai, Y-S., Jou, Y. C., Lee, G. F., Chen, Y. C., Shiau, A-L., Tsai, H. T., Wu, C-L. & Tzai, T. S., 2009 Jan 1, In : Urology. 73, 1, p. 188-192 5 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Staining and Labeling
prothymosin alpha
Transitional Cell Carcinoma
Neoplasms
12 Citations (Scopus)

Aberrant RNA splicing in RHD 7-9 exons of DEL individuals in Taiwan: A mechanism study

Liu, H. C., Eng, H. L., Yang, Y. F., Wang, Y. H., Lin, K. T., Wu, H-L. & Lin, T. M., 2010 Jun 1, In : Biochimica et Biophysica Acta - General Subjects. 1800, 6, p. 565-573 9 p.

Research output: Contribution to journalArticle

RNA Splicing
Taiwan
Exons
RNA
Alleles
37 Citations (Scopus)

A biological strategy for fabrication of Au/EGFP nanoparticle conjugates retaining bioactivity

Tsai, C. Y., Shiau, A-L., Cheng, P. C., Shieh, D-B., Chen, D-H., Chou, C-H., Yeh, C-S. & Wu, C-L., 2004 Jul 1, In : Nano letters. 4, 7, p. 1209-1212 4 p.

Research output: Contribution to journalArticle

retaining
Bioactivity
DNA
deoxyribonucleic acid
Nanoparticles
14 Citations (Scopus)

Abrogation of streptococcal pyrogenic exotoxin B-mediated suppression of phagocytosis in U937 cells by Cordyceps sinensis mycelium via production of cytokines

Kuo, C. F., Chen, C. C., Lin, C. F., Jan, M. S., Huang, R. Y., Luo, Y. H., Chuang, W. J., Sheu, C. C. & Lin, Y. S., 2007 Feb 1, In : Food and Chemical Toxicology. 45, 2, p. 278-285 8 p.

Research output: Contribution to journalArticle

Cordyceps
Ophiocordyceps sinensis
exotoxins
U937 Cells
Mycelium
107 Citations (Scopus)

Absence of an Essential Role for Thymic Stromal Lymphopoietin Receptor in Murine B-Cell Development

Carpino, N., Thierfelder, W. E., Chang, M. S., Saris, C., Turner, S. J., Ziegler, S. F. & Ihle, J. N., 2004 Mar 1, In : Molecular and Cellular Biology. 24, 6, p. 2584-2592 9 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Lymphocytes
Cytokine Receptors
Immunoglobulin M
Lymphopoiesis
5 Citations (Scopus)

Acarbose Decreases the Rheumatoid Arthritis Risk of Diabetic Patients and Attenuates the Incidence and Severity of Collagen-induced Arthritis in Mice

Chen, H. H., Chen, D. Y., Chao, Y. H., Chen, Y. M., Wu, C. L., Lai, K. L., Lin, C. H. & Lin, C. C., 2015 Dec 18, In : Scientific reports. 5, 18288.

Research output: Contribution to journalArticle

Acarbose
Experimental Arthritis
Rheumatoid Arthritis
Incidence
Diabetes Mellitus
26 Citations (Scopus)

Acetylcorynoline attenuates dopaminergic neuron degeneration and α-synuclein aggregation in animal models of Parkinson's disease

Fu, R. H., Wang, Y. C., Chen, C. S., Tsai, R. T., Liu, S. P., Chang, W. L., Lin, H. L., Lu, C. H., Wei, J. R., Wang, Z. W., Shyu, W. C. & Lin, S. Z., 2014 Jul, In : Neuropharmacology. 82, p. 108-120 13 p.

Research output: Contribution to journalArticle

Synucleins
Nerve Degeneration
Dopaminergic Neurons
Parkinson Disease
Animal Models
23 Citations (Scopus)

A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity

Yang, H. J., Yen, M. C., Lin, C. C., Lin, C. M., Chen, Y. L., Weng, T. Y., Huang, T. T., Wu, C-L. & Lai, M-D., 2010 Jul 1, In : Experimental Biology and Medicine. 235, 7, p. 869-876 8 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Enzyme Inhibitors
Tumors
NAD
Therapeutic Uses
26 Citations (Scopus)
Aeromonas hydrophila
Aeromonas
Taiwan
gentamicin A
Wounds and Injuries
1 Citation (Scopus)

A computerized management system for cell bank

Wu, C. L., Wu, P. & Shiau, A. L., 1999 Nov 15, In : Analytical Biochemistry. 275, 2, p. 260-262 3 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Acquisition of an enhanced aggressive phenotype in human lung cancer cells selected by suboptimal doses of cisplatin following cell deattachment and reattachment

Hsieh, J. L., Lu, C. S., Huang, C. L., Shieh, G. S., Su, B. H., Su, Y. C., Lee, C. H., Chang, M. Y., Wu, C. L. & Shiau, A. L., 2012 Aug 1, In : Cancer Letters. 321, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

Cisplatin
Lung Neoplasms
Phenotype
Aptitude
gemcitabine
27 Citations (Scopus)

ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells

Chang, Y. S., Tsai, C. T., Huangfu, C. A., Huang, W. Y., Lei, H. Y., Lin, C. F., Su, I. J., Chang, W. T., Wu, P. H., Chen, Y. T., Hung, J. H., Young, K. C. & Lai, M. D., 2011 Mar 1, In : Journal of Cellular Biochemistry. 112, 3, p. 881-893 13 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Endoplasmic Reticulum Stress
Liver
Up-Regulation
Lipids
68 Citations (Scopus)

Activation of coagulation and fibrinolysis during dengue virus infection

Huang, Y. H., Liu, C-C., Wang, S-T., Lei, H. Y., Liu, H-S., Lin, Y-S., Wu, H-L. & Yeh, T-M., 2001 Feb 14, In : Journal of Medical Virology. 63, 3, p. 247-251 5 p.

Research output: Contribution to journalArticle

Severe Dengue
Dengue Virus
Fibrinolysis
Virus Diseases
Dengue
6 Citations (Scopus)
Nonesterified Fatty Acids
Liver
Hep G2 Cells
High Fat Diet
Sterol Regulatory Element Binding Protein 1
12 Citations (Scopus)

Activation of human and bovine plasminogens by the microplasmin and streptokinase complex

Shi, G. Y., Chang, B. I., Wu, D. H., Ha, Y. M. & Wu, H-L., 1990 May 1, In : Thrombosis Research. 58, 3, p. 317-329 13 p.

Research output: Contribution to journalArticle

Streptokinase
Fibrinolysin
Plasminogen
Population Groups
Human Activities
6 Citations (Scopus)

Acute meningoencephalitis as initial presentation of human immunodeficiency virus infection: Report of two cases

Li, C. M., Lee, Y. Y. & Ho, Y. R., 2002 Sep 1, In : Journal of Microbiology, Immunology and Infection. 35, 3, p. 195-198 4 p.

Research output: Contribution to journalArticle

Meningoencephalitis
Virus Diseases
HIV
Central Nervous System Infections
Southeastern Asia
37 Citations (Scopus)

Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection

Hsieh, J. L., Shen, P. C., Shiau, A-L., Jou, I. M., Lee, C. H., Teo, M. L., Wang, C-R., Chao, J., Chao, L. & Wu, C-L., 2009 Feb 1, In : Human Gene Therapy. 20, 2, p. 147-158 12 p.

Research output: Contribution to journalArticle

Anterior Cruciate Ligament
Adenoviridae
Osteoarthritis
Disease Progression
Genes
4 Citations (Scopus)

Adenovirus-mediated prothymosin α gene transfer inhibits the development of atherosclerosis in apoe-deficient mice

Chang, M. Y., Yang, Y. S., Tsai, M. L., Lee, C. H., Chang, C. J., Shiau, A. L. & Wu, C. L., 2014 Mar 15, In : International Journal of Biological Sciences. 10, 4, p. 358-366 9 p.

Research output: Contribution to journalArticle

gene transfer
Apolipoproteins E
Adenoviridae
atherosclerosis
antioxidant
6 Citations (Scopus)

A disease model of muscle necrosis caused by aeromonas dhakensis infection in caenorhabditis elegans

Chen, P. L., Chen, Y. W., Ou, C. C., Lee, T. M., Wu, C. J., Ko, W. C. & Chen, C. S., 2017 Jan 4, In : Frontiers in Microbiology. 7, JAN, 2058.

Research output: Contribution to journalArticle

Aeromonas
Caenorhabditis elegans
Necrosis
Muscles
RNA Interference
12 Citations (Scopus)
Aeromonas
Taiwan
Diarrhea
HT29 Cells
Anti-Infective Agents
4 Citations (Scopus)

Agaricus blazei Murill ameliorates myocardial ischemia-reperfusion injury

Huang, C. H., Tsai, H. N., Peng, R. H., Hsieh, Y. H., Chuang, W-J., Hsu, G. C., Huang, W-Y. & Chen, W. J., 2010 Dec 1, In : Acta Cardiologica Sinica. 26, 4, p. 235-241 7 p.

Research output: Contribution to journalArticle

Agaricus
Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Myocardial Reperfusion
4 Citations (Scopus)

Alignment using genetic programming with causal trees for identification of protein functions

Hung, C. M., Huang, Y-M. & Chang, M-S., 2006 Sep 1, In : Nonlinear Analysis, Theory, Methods and Applications. 65, 5, p. 1070-1093 24 p.

Research output: Contribution to journalArticle

Genetic programming
Genetic Programming
Identification (control systems)
Alignment
Proteins
25 Citations (Scopus)

Altered synaptophysin expression in the rat spinal cord after chronic constriction injury of sciatic nerve

Chou, A. K., Muhammad, R., Huang, S. M., Chen, J. T., Wu, C-L., Lin, C. R., Lee, T. H., Lin, S. H., Lu, C. Y. & Yang, L. C., 2002 Nov 29, In : Neuroscience Letters. 333, 3, p. 155-158 4 p.

Research output: Contribution to journalArticle

Synaptophysin
Hyperalgesia
Sciatic Nerve
Constriction
Spinal Cord
77 Citations (Scopus)

Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

Li, Y. T., Chen, S. Y., Wang, C. R., Liu, M. F., Lin, C. C., Jou, I. M., Shiau, A. L. & Wu, C. L., 2012 Oct 1, In : Arthritis and Rheumatism. 64, 10, p. 3240-3245 6 p.

Research output: Contribution to journalArticle

Lentivirus
Experimental Arthritis
MicroRNAs
Rheumatoid Arthritis
Macrophage Colony-Stimulating Factor Receptors
37 Citations (Scopus)

Amelioration of collagen-induced arthritis in rats by adenovirus-mediated PTEN gene transfer

Wang, C-R., Shiau, A-L., Chen, S. Y., Lin, L. L., Tai, M. H., Shieh, G. S., Lin, P. R., Yo, Y. T., Lee, C. H., Kuo, S. M., Liu, M-F., Jou, I. M., Yang, C-Y., Shen, P. C., Lee, H. L. & Wu, C-L., 2008 Jun 1, In : Arthritis and Rheumatism. 58, 6, p. 1650-1656 7 p.

Research output: Contribution to journalArticle

Experimental Arthritis
Adenoviridae
Phosphatidylinositol 3-Kinase
Vascular Endothelial Growth Factor A
Genes
135 Citations (Scopus)

Amelioration of collagen-induced arthritis in rats by Nanogold

Tsai, C. Y., Shiau, A-L., Chen, S. Y., Chen, Y-H., Cheng, P. C., Chang, M. Y., Chen, D-H., Chou, C-H., Wang, C-R. & Wu, C-L., 2007 Feb 1, In : Arthritis and Rheumatism. 56, 2, p. 544-554 11 p.

Research output: Contribution to journalArticle

Experimental Arthritis
Rheumatoid Arthritis
Synovial Fluid
Ankle Joint
Macrophages
7 Citations (Scopus)

Amelioration of experimental arthritis by a telomerase-dependent conditionally replicating adenovirus that targets synovial fibroblasts

Chen, S. Y., Shiau, A-L., Shieh, G. S., Su, C. H., Lee, C. H., Lee, H. L., Wang, C-R. & Wu, C-L., 2009 Nov 1, In : Arthritis and Rheumatism. 60, 11, p. 3290-3302 13 p.

Research output: Contribution to journalArticle

Experimental Arthritis
Telomerase
Adenoviridae
Fibroblasts
Rheumatoid Arthritis
4 Citations (Scopus)
Intra-Articular Injections
Experimental Arthritis
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Joints
31 Citations (Scopus)

Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140-3p and 140-5p

Peng, J. S., Chen, S. Y., Wu, C. L., Chong, H. E., Ding, Y. C., Shiau, A. L. & Wang, C. R., 2016 Feb 1, In : Arthritis and Rheumatology. 68, 2, p. 370-381 12 p.

Research output: Contribution to journalArticle

Experimental Arthritis
MicroRNAs
Fibroblasts
Arthritis
Rheumatoid Arthritis
1 Citation (Scopus)

Amelioration of experimentally induced arthritis by reducing reactive oxygen species production through the intra-articular injection of water-soluble fullerenol

Kuo, W. S., Weng, C-T., Chen, J. H., Wu, C-L., Shiau, A-L., Hsieh, J. L., So, E. C., Wu, P-T. & Chen, S. Y., 2019 Jun, In : Nanomaterials. 9, 6, 909.

Research output: Contribution to journalArticle

Open Access
Reactive Oxygen Species
Oxygen
Water
Nitric oxide
Cartilage
24 Citations (Scopus)

Amelioration of rat collagen-induced arthritis through CD4+ T cells apoptosis and synovial interleukin-17 reduction by indoleamine 2,3-dioxygenase gene therapy

Chen, S. Y., Wu, C. L., Lai, M. D., Lin, C. C., Yo, Y. T., Jou, I. M., Lee, C. H., Weng, C. T., Shiau, A. L. & Wang, C. R., 2011 Feb 1, In : Human Gene Therapy. 22, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Experimental Arthritis
Interleukin-17
Genetic Therapy
Kynurenine
19 Citations (Scopus)

A methionine-restricted diet and endurance exercise decrease bone mass and extrinsic strength but increase intrinsic strength in growing male rats

Huang, T-H., Lewis, J. L., Lin, H. S., Kuo, L. T., Mao, S. W., Tai, Y. S., Chang, M-S., Ables, G. P., Perrone, C. E. & Yang, R. S., 2014 Jan 1, In : Journal of Nutrition. 144, 5, p. 621-630 10 p.

Research output: Contribution to journalArticle

Methionine
Diet
Bone and Bones
Bone Density
Body Weight
2 Citations (Scopus)

A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli

Kuo, C. J., Wang, S. T., Lin, C. M., Chiu, H. C., Huang, C. R., Lee, D. Y., Chang, G. D., Chou, T. C., Chen, J. W. & Chen, C. S., 2018 Mar 1, In : Cell Death and Disease. 9, 3, 381.

Research output: Contribution to journalArticle

Enterohemorrhagic Escherichia coli
Fumarates
Virulence
Caenorhabditis elegans
Escherichia coli Infections
19 Citations (Scopus)
Gallbladder Neoplasms
ras Genes
Cholangiocarcinoma
Paraffin
Point Mutation
1 Citation (Scopus)

A negative regulatory element in a prespore-specific promoter of Dictyostelium discoideum

Hsu, Y. S., Chang, W-T., Newell, P. C. & Gross, J. D., 1999 Oct 6, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1447, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

Galactosidases
Dictyostelium
Genes
Assays
Electrophoretic Mobility Shift Assay
51 Citations (Scopus)

Angiostatin antagonizes the action of VEGF-A in human endothelial cells via two distinct pathways

Chen, Y. H., Wu, H-L., Chen, C. K., Huang, Y. H., Yang, B-C. & Wu, L-W., 2003 Oct 24, In : Biochemical and Biophysical Research Communications. 310, 3, p. 804-810 7 p.

Research output: Contribution to journalArticle

Angiostatins
Endothelial cells
Vascular Endothelial Growth Factor A
Endothelial Cells
Human Umbilical Vein Endothelial Cells
3 Citations (Scopus)

Angiostatin K1-3 induces E-selectin via AP1 and Ets1: A mediator for anti-angiogenic action of K1-3

Chen, Y. H., Huang, Y. H., Wu, H. L., Wu, M. P., Chang, W. T., Kuo, Y. Z., Lu, K. C. & Wu, L. W., 2008 Oct 24, In : Journal of Thrombosis and Haemostasis. 6, 11, p. 1953-1961 9 p.

Research output: Contribution to journalArticle

Angiostatins
E-Selectin
Caveolin 1
Messenger RNA
Angiogenesis Inhibitors
5 Citations (Scopus)

An HDAC inhibitor enhances cancer therapeutic efficiency of RNA polymerase III promoter-driven IDO shRNA

Yen, M. C., Weng, T. Y., Chen, Y. L., Lin, C. C., Chen, C. Y., Wang, C. Y., Chao, H. L., Chen, C. S. & Lai, M. D., 2013 Jun 1, In : Cancer Gene Therapy. 20, 6, p. 351-357 7 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
RNA Polymerase III
Histone Deacetylase Inhibitors
Small Interfering RNA
Neoplasms
17 Citations (Scopus)

An HDAC inhibitor enhances the antitumor activity of a CMV promoter-driven DNA vaccine

Lai, M. D., Chen, C. S., Yang, C. R., Yuan, S. Y., Tsai, J. J., Tu, C. F., Wang, C. C., Yen, M. C. & Lin, C. C., 2010 Mar 1, In : Cancer Gene Therapy. 17, 3, p. 203-211 9 p.

Research output: Contribution to journalArticle

DNA Vaccines
Histone Deacetylase Inhibitors
Cytomegalovirus
Luciferases
Histone Deacetylases
118 Citations (Scopus)

An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium

Thomason, P. A., Traynor, D., Cavet, G., Chang, W-T., Harwood, A. J. & Kay, R. R., 1998 May 15, In : EMBO Journal. 17, 10, p. 2838-2845 8 p.

Research output: Contribution to journalArticle

Signal transduction
Dictyostelium
Phosphoric Diester Hydrolases
Protein Kinases
Signal Transduction
15 Citations (Scopus)

An in vitro monitoring system for simulated thermal process in cryosurgery

Yang, W-H., Peng, H. H., Chang, H-C., Shen, S-Y., Wu, C-L. & Chang, C-H., 2000 Jan 1, In : Cryobiology. 40, 2, p. 159-170 12 p.

Research output: Contribution to journalArticle

Cryosurgery
cryosurgery
Hot Temperature
heat
Temperature
32 Citations (Scopus)

An iron-binding protein, Dpr, decreases hydrogen peroxide stress and protects Streptococcus pyogenes against multiple stresses

Tsou, C. C., Chiang-Ni, C., Lin, Y. S., Chuang, W. J., Lin, M. T., Liu, C. C. & Wu, J. J., 2008 Sep 1, In : Infection and Immunity. 76, 9, p. 4038-4045 8 p.

Research output: Contribution to journalArticle

Iron-Binding Proteins
Streptococcus pyogenes
Hydrogen Peroxide
Iron
Peroxides
47 Citations (Scopus)
oligonucleotides
Oligonucleotides
Gold
microelectromechanical systems
MEMS
60 Citations (Scopus)

A novel adenylyl cyclase detected in rapidly developing mutants of Dictyostelium

Kim, H. J., Chang, W-T., Meima, M., Gross, J. D. & Schaap, P., 1998 Nov 20, In : Journal of Biological Chemistry. 273, 47, p. 30859-30862 4 p.

Research output: Contribution to journalArticle

Dictyostelium
Adenylyl Cyclases
Genes
Phosphoric Diester Hydrolases
Phosphodiesterase 3 Inhibitors
11 Citations (Scopus)

A novel bidirectional expression system for simultaneous expression of both the protein-coding genes and short hairpin RNAs in mammalian cells

Hung, C. F., Cheng, T. L., Wu, R. H., Teng, C. F. & Chang, W-T., 2006 Jan 27, In : Biochemical and Biophysical Research Communications. 339, 4, p. 1035-1042 8 p.

Research output: Contribution to journalArticle

Ribonuclease P
Poly(ADP-ribose) Polymerases
Small Interfering RNA
blasticidin S deaminase
Genes
10 Citations (Scopus)

A novel cancer therapeutic using thrombospondin 1 in dendritic cells

Weng, T. Y., Huang, S. S., Yen, M. C., Lin, C. C., Chen, Y. L., Lin, C. M., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2014 Jan 1, In : Molecular Therapy. 22, 2, p. 292-302 11 p.

Research output: Contribution to journalArticle

Thrombospondin 1
Dendritic Cells
Neoplasms
Small Interfering RNA
Therapeutics
54 Citations (Scopus)

A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA

Yen, M. C., Lin, C. C., Chen, Y. L., Huang, S. S., Yang, H. J., Chang, C. P., Lei, H. Y. & Lai, M. D., 2009 Jan 15, In : Clinical Cancer Research. 15, 2, p. 641-649 9 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Skin Neoplasms
Small Interfering RNA
Neoplasms
Therapeutics