Department of Biotechnology and Bioindustry Sciences

Research Output

2020

A selective Aurora-A 5′-UTR siRNA inhibits tumor growth and metastasis

Lai, C. H., Chen, R. Y., Hsieh, H. P., Tsai, S. J., Chang, K. C., Yen, C. J., Huang, Y. C., Liu, Y. W., Lee, J. C., Lai, Y. C., Hung, L. Y. & Lin, B. W., 2020 Mar 1, In : Cancer Letters. 472, p. 97-107 11 p.

Research output: Contribution to journalArticle

Bile acid and bile acid transporters are involved in the pathogenesis of acute hepatopancreatic necrosis disease in white shrimp Litopenaeus vannamei

Kumar, R., Ng, T. H., Chang, C. C., Tung, T. C., Lin, S. S., Lo, C. F. & Wang, H. C., 2020 Jan 1, In : Cellular Microbiology. 22, 1, e13127.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Biocontrol of acute hepatopancreatic necrosis disease (AHPND) in shrimp using a microalgal-bacterial consortium

Chang, Y. H., Kuo, W. C., Wang, H. C. & Chen, Y. M., 2020 May 15, In : Aquaculture. 521, 734990.

Research output: Contribution to journalArticle

EPA and DHA can modulate cell death via inhibition of the Fas/tBid-mediated signaling pathway with ISKNV infection in grouper fin cell line (GF-1) cells

Chen, K. W., Chiu, H. W., Chiu, Y. W., Wu, J. L. & Hong, J. R., 2020 Feb, In : Fish and Shellfish Immunology. 97, p. 608-616 9 p.

Research output: Contribution to journalArticle

Hippo Signaling-Mediated Mechanotransduction in Cell Movement and Cancer Metastasis

Chang, Y. C., Wu, J. W., Wang, C. W. & Jang, A. C. C., 2020 Jan 31, In : Frontiers in Molecular Biosciences. 6, 157.

Research output: Contribution to journalReview article

Open Access

Mrnasi index: Machine learning in mining lung adenocarcinoma stem cell biomarkers

Zhang, Y., Li, H., Tseng, J. T. C., Lien, I. C., Li, F. & Wu, W., 2020 Mar, In : Genes. 11, 3, 257.

Research output: Contribution to journalArticle

Open Access

Penaeus vannamei serine proteinase inhibitor 7 (LvSerpin7) acts as an immune brake by regulating the proPO system in AHPND-affected shrimp

Apitanyasai, K., Chang, C. C., Ng, T. H., Ng, Y. S., Liou, J. H., Lo, C. F., Lin, S. S. & Wang, H. C., 2020 May, In : Developmental and Comparative Immunology. 106, 103600.

Research output: Contribution to journalArticle

Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis

Hung, C. Y., Hsu, T. I., Chuang, J. Y., Su, T. P., Chang, W. C. & Hung, J. J., 2020 Jan 1, In : Molecular Neurobiology. 57, 1, p. 261-277 17 p.

Research output: Contribution to journalArticle

2019

Angioimmunoblastic T-cell lymphoma in Taiwan reveals worse progression-free survival for RHOA G17V mutated subtype

Hsu, Y. T., Wang, Y. C., Chen, R. Y., Hung, L. Y., Li, S. S., Yen, C. C., Chen, T. Y., Medeiros, L. J. & Chang, K. C., 2019 Jan 1, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

A novel zebrafish model to emulate lung injury by folate deficiency-induced swim bladder defectiveness and protease/antiprotease expression imbalance

Lee, G. H., Cheng, N. W., Yu, H. H., Tsai, J. N., Liu, T., Wen, Z. H., Chen, B. H. & Fu, T. F., 2019 Dec 1, In : Scientific reports. 9, 1, 12633.

Research output: Contribution to journalArticle

Open Access

Aurantiochytrium dietary supplements reduce intra-cohort cannibalism among orange-spotted groupers (Epinephelus coioides) by modulating brain 5-HT and serum cortisol

Chang, Y. H., Lin, Y. H., Hsieh, C. H. & Chen, Y. M., 2019 Mar 15, In : Aquaculture. 502, p. 202-211 10 p.

Research output: Contribution to journalArticle

CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity

Chen, R. Y., Yen, C. J., Liu, Y. W., Guo, C. G., Weng, C. Y., Lai, C. H., Wang, Y. M., Lin, Y. J. & Hung, L. Y., 2019 Jan 1, (Accepted/In press) In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Development and application of a high-content virion display human GPCR array

Syu, G. D., Wang, S. C., Ma, G., Liu, S., Pearce, D., Prakash, A., Henson, B., Weng, L. C., Ghosh, D., Ramos, P., Eichinger, D., Pino, I., Dong, X., Xiao, J., Wang, S., Tao, N., Kim, K. S., Desai, P. J. & Zhu, H., 2019 Dec 1, In : Nature communications. 10, 1, 1997.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Dongshaea marina gen. Nov., sp. nov., a facultatively anaerobic marine bacterium that ferments glucose with gas production

Huang, S. P., Chen, T. Y., Chen, J. S., Wang, L. T., Huang, L., Lin, S. T., Wei, C. L., Lin, S., Wang, P. L., Chen, Y. M. & Shieh, W. Y., 2019 Jan 1, In : International Journal of Systematic and Evolutionary Microbiology. 69, 11, p. 3318-3325 8 p., 3080.

Research output: Contribution to journalArticle

Erratum: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy (Oncotarget (2015) 6 (13671–13687) DOI: 10.18632/oncotarget.3701)

Hsu, T. I., Chen, Y. J., Hung, C. Y., Wang, Y. C., Lin, S. J., Su, W. C., Lai, M. D., Kim, S. Y., Wang, Q., Qian, K., Goto, M., Zhao, Y., Kashiwada, Y., Lee, K. H., Chang, W. C. & Hung, J. J., 2019 Jan 1, In : Oncotarget. 10, 60, p. 6536-6537 2 p.

Research output: Contribution to journalComment/debate

Evolutionary constraints on species diversity in marine bacterioplankton communities

Lu, H-P., Yeh, Y. C., Shiah, F. K., Gong, G. C. & Hsieh, C. H., 2019 Apr 1, In : ISME Journal. 13, 4, p. 1032-1041 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Expanding the mesodermal transcriptional network by genome-wide identification of Zinc finger homeodomain 1 (Zfh1) targets

Wu, W. H., Kuo, T. H., Kao, C. W., Girardot, C., Hung, S. J., Liu, T., Furlong, E. E. M. & Liu, Y-H., 2019 Jul 1, In : FEBS Letters. 593, 14, p. 1698-1710 13 p.

Research output: Contribution to journalArticle

Gene expression signature-based approach identifies antifungal drug ciclopirox as a novel inhibitor of hmga2 in colorectal cancer

Huang, Y. M., Cheng, C. H., Pan, S. L., Yang, P. M., Lin, D. Y. & Lee, K. H., 2019 Nov, In : Biomolecules. 9, 11, 688.

Research output: Contribution to journalArticle

Open Access

Genome organization and definition of the Penaeus monodon viral responsive protein 15 (PmVRP15) promoter

Jaree, P., Kawai, T., Lo, C. F., Tassanakajon, A. & Somboonwiwat, K., 2019 Oct, In : Fish and Shellfish Immunology. 93, p. 997-1006 10 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis

Yen, C. J., Yang, S. T., Chen, R. Y., Huang, W., Chayama, K., Lee, M. H., Yang, S. J., Lai, H. S., Yen, H. Y., Hsiao, Y. W., Wang, J. M., Lin, Y. J. & Hung, L. Y., 2019 Jun 6, In : Journal of biomedical science. 26, 1, 44.

Research output: Contribution to journalArticle

Open Access

Hepatoma-derived growth factor supports the antiapoptosis and profibrosis of pancreatic stellate cells

Chen, Y. T., Chen, F. W., Chang, T. H., Wang, T. W., Hsu, T. P., Chi, J. Y., Hsiao, Y. W., Li, C. F. & Wang, J. M., 2019 Aug 10, In : Cancer Letters. 457, p. 180-190 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

ICTV virus taxonomy profile: Nimaviridae

ICTV Report Consortium, 2019 Jul, In : Journal of General Virology. 100, 7, p. 1053-1054 2 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation

Wang, C. H., Hung, P. W., Chiang, C. W., Lombès, M., Chen, C. H., Lee, K. H., Lo, Y. C., Wu, M. H., Chang, W. C. & Lin, D. Y., 2019 Aug, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 8, p. 1282-1297 16 p.

Research output: Contribution to journalArticle

Impact of Tilapia hepcidin 2-3 dietary supplementation on the gut microbiota profile and immunomodulation in the grouper (Epinephelus lanceolatus)

Ting, C. H., Pan, C. Y., Chen, Y. C., Lin, Y. C., Chen, T. Y., Rajanbabu, V. & Chen, J. Y., 2019 Dec 1, In : Scientific reports. 9, 1, 19047.

Research output: Contribution to journalArticle

Open Access

Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis

Lu, F. I., Wang, Y. T., Wang, Y. S., Wu, C. Y. & Li, C. C., 2019 Sep 1, In : FASEB Journal. 33, 9, p. 9959-9973 15 p.

Research output: Contribution to journalArticle

LvRas and LvRap are both important for WSSV replication in Litopenaeus vannamei

Tseng, Y. T., Kumar, R. & Wang, H. C., 2019 May, In : Fish and Shellfish Immunology. 88, p. 150-160 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Potassium Stimulation of IAA Transport Mediated by the Arabidopsis Importer AUX1 Investigated in a Heterologous Yeast System

Huang, L. K., Liao, Y. Y., Lin, W. H., Lin, S-M., Liu, T. Y., Lee, C. H. & Pan, R. L., 2019 Jun 15, In : Journal of Membrane Biology. 252, 2-3, p. 183-194 12 p.

Research output: Contribution to journalArticle

Selective expression of a “correct cloud” of Dscam in crayfish survivors after second exposure to the same pathogen

Ng, T. H., Kumar, R., Apitanyasai, K., He, S. T., Chiu, S. P. & Wang, H. C., 2019 Sep, In : Fish and Shellfish Immunology. 92, p. 430-437 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

SlSWEET1a is involved in glucose import to young leaves in tomato plants

Ho, L. H., Klemens, P. A. W., Neuhaus, H. E., Ko, H. Y., Hsieh, S. Y. & Guo, W. J., 2019 Jun, In : Journal of experimental botany. 70, 12, p. 3241-3254 14 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Stem cells as a potential therapy for diabetes mellitus: A call-to-action in Latin America

Solis, M. A., Moreno Velásquez, I., Correa, R. & Huang, L. L. H., 2019 Feb 18, In : Diabetology and Metabolic Syndrome. 11, 1, 20.

Research output: Contribution to journalReview article

Open Access

Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirAvp and pirBvp toxins and activation of the cry-like pore-forming domain

Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., 2019 Apr, In : Toxins. 11, 4, 233.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

The expression profile and prognostic significance of metallothionein genes in colorectal cancer

Hung, K. C., Huang, T. C., Cheng, C. H., Cheng, Y. W., Lin, D. Y., Fan, J. J. & Lee, K. H., 2019 Aug 2, In : International journal of molecular sciences. 20, 16, 3849.

Research output: Contribution to journalArticle

Open Access

The gene structure and hypervariability of the complete Penaeus monodon Dscam gene

Apitanyasai, K., Huang, S. W., Ng, T. H., He, S. T., Huang, Y. H., Chiu, S. P., Tseng, K. C., Lin, S. S., Chang, W. C., Baldwin-Brown, J. G., Long, A. D., Lo, C. F., Yu, H. T. & Wang, H. C., 2019 Dec 1, In : Scientific reports. 9, 1, 16595.

Research output: Contribution to journalArticle

Open Access

The Pathobiome in Animal and Plant Diseases

Bass, D., Stentiford, G. D., Wang, H. C., Koskella, B. & Tyler, C. R., 2019 Nov, In : Trends in Ecology and Evolution. 34, 11, p. 996-1008 13 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

The role of ubiquitin-specific peptidases in cancer progression

Young, M. J., Hsu, K. C., Lin, T. E., Chang, W. C. & Hung, J. J., 2019 May 27, In : Journal of biomedical science. 26, 1, 42.

Research output: Contribution to journalReview article

Open Access
2018

Antibody profiling of kawasaki disease using Escherichia coli proteome microarrays

Kuo, H. C., Huang, Y. H., Chung, F. H., Chen, P. C., Sung, T. C., Chen, Y. W., Hsieh, K. S., Chen, C. S. & Syu, G. D., 2018 Mar, In : Molecular and Cellular Proteomics. 17, 3, p. 472-481 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, Y-M., 2018 Jun, In : Redox Biology. 16, p. 104-112 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
1 Citation (Scopus)

Complete genome sequence and phylogenetic analysis of megalocytivirus RSIV-Ku: A natural recombination infectious spleen and kidney necrosis virus

Shiu, J. Y., Hong, J. R., Ku, C. C. & Wen, C. M., 2018 Apr 1, In : Archives of Virology. 163, 4, p. 1037-1042 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Contrasting the relative importance of species sorting and dispersal limitation in shaping marine bacterial versus protist communities

Wu, W., Lu, H. P., Sastri, A., Yeh, Y. C., Gong, G. C., Chou, W. C. & Hsieh, C. H., 2018 Feb 1, In : ISME Journal. 12, 2, p. 485-494 10 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)

Development of a computational promoter with highly efficient expression in tumors

Ho, S. Y., Chang, B. H., Chung, C. H., Lin, Y. L., Chuang, C. H., Hsieh, P. J., Huang, W. C., Tsai, N. M., Huang, S. C., Liu, Y. K., Lo, Y. C. & Liao, K. W., 2018 Apr 27, In : BMC cancer. 18, 1, 480.

Research output: Contribution to journalArticle

4 Citations (Scopus)
1 Citation (Scopus)

Functional characteristics of the flying squirrel's cecal microbiota under a leaf-based diet, based on multiple meta-omic profiling

Lu, H. P., Liu, P. Y., Wang, Y. B., Hsieh, J. F., Ho, H. C., Huang, S. W., Lin, C. Y., Hsieh, C. H. & Yu, H. T., 2018 Jan 4, In : Frontiers in Microbiology. 8, JAN, 2622.

Research output: Contribution to journalArticle

Open Access

Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C. J., Ai, Y. L., Tsai, H. W., Chan, S. H., Yen, C. S., Cheng, K. H., Lee, Y. P., Kao, C. W., Wang, Y. C., Chen, Y. L., Lin, C. H., Liu, T., Tsai, H. P., Wang, J. R., Su, I. J. & Huang, W., 2018 Sep, In : Hepatology. 68, 3, p. 815-826 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Measuring Ligand Binding Kinetics to Membrane Proteins Using Virion Nano-oscillators

Ma, G., Syu, G. D., Shan, X., Henson, B., Wang, S., Desai, P. J., Zhu, H. & Tao, N., 2018 Sep 12, In : Journal of the American Chemical Society. 140, 36, p. 11495-11501 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Medical Applications of Collagen and Hyaluronan in Regenerative Medicine

Huang, L. L. H., Chen, Y. H. A., Zhuo, Z. Y., Hsieh, Y. T., Yang, C. L., Chen, W. T., Lin, J. Y., Lin, Y. X., Jiang, J. T., Zhuang, C. H., Wang, Y. C., Nguyendac, H., Lin, K. W. & Liu, W. L., 2018 Jan 1, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 285-306 22 p. (Advances in Experimental Medicine and Biology; vol. 1077).

Research output: Chapter in Book/Report/Conference proceedingChapter

Novel Biomaterials for Regenerative Medicine

Huang, L. L-H., 2018, Novel Biomaterials for Regenerative Medicine: Adv Exp Med Biol, Vol. 1077. Chun, H. J. (ed.). Springer Nature

Research output: Chapter in Book/Report/Conference proceedingChapter