Department of Biotechnology and Bioindustry Sciences

Research Output 1974 2019

Filter
Article
2019

Aurantiochytrium dietary supplements reduce intra-cohort cannibalism among orange-spotted groupers (Epinephelus coioides) by modulating brain 5-HT and serum cortisol

Chang, Y. H., Lin, Y. H., Hsieh, C. H. & Chen, Y-M., 2019 Mar 15, In : Aquaculture. 502, p. 202-211 10 p.

Research output: Contribution to journalArticle

Epinephelus coioides
cannibalism
serotonin
cortisol
dietary supplements

Bile acid and bile acid transporters are involved in the pathogenesis of acute hepatopancreatic necrosis disease in white shrimp Litopenaeus vannamei

Kumar, R., Ng, T. H., Chang, C. C., Tung, T. C., Lin, S. S., Lo, C. F. & Wang, H. C., 2019 Jan 1, (Accepted/In press) In : Cellular Microbiology. e13127.

Research output: Contribution to journalArticle

Bile Acids and Salts
Necrosis
Vibrio parahaemolyticus
Stomach
Bacterial Secretion Systems
2 Citations (Scopus)

CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity

Chen, R. Y., Yen, C. J., Liu, Y. W., Guo, C. G., Weng, C. Y., Lai, C. H., Wang, Y. M., Lin, Y. J. & Hung, L. Y., 2019 Jan 1, (Accepted/In press) In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Hepatocellular Carcinoma
Proteins
Interleukin-8
Interleukin-6

Development and application of a high-content virion display human GPCR array

Syu, G. D., Wang, S. C., Ma, G., Liu, S., Pearce, D., Prakash, A., Henson, B., Weng, L. C., Ghosh, D., Ramos, P., Eichinger, D., Pino, I., Dong, X., Xiao, J., Wang, S., Tao, N., Kim, K. S., Desai, P. J. & Zhu, H., 2019 Dec 1, In : Nature communications. 10, 1, 1997.

Research output: Contribution to journalArticle

Open Access
G-Protein-Coupled Receptors
Virion
proteins
Ligands
ligands
1 Citation (Scopus)

Evolutionary constraints on species diversity in marine bacterioplankton communities

Lu, H-P., Yeh, Y. C., Shiah, F. K., Gong, G. C. & Hsieh, C. H., 2019 Apr 1, In : ISME Journal. 13, 4, p. 1032-1041 10 p.

Research output: Contribution to journalArticle

bacterioplankton
Seawater
species diversity
seawater
Politics

Expanding the mesodermal transcriptional network by genome-wide identification of Zinc finger homeodomain 1 (Zfh1) targets

Wu, W. H., Kuo, T. H., Kao, C. W., Girardot, C., Hung, S. J., Liu, T., Furlong, E. E. M. & Liu, Y-H., 2019 Jul 1, In : FEBS Letters. 593, 14, p. 1698-1710 13 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Zinc Fingers
Zinc
Hemocytes
Genes

Gene expression signature-based approach identifies antifungal drug ciclopirox as a novel inhibitor of hmga2 in colorectal cancer

Huang, Y. M., Cheng, C. H., Pan, S. L., Yang, P. M., Lin, D. Y. & Lee, K. H., 2019 Nov, In : Biomolecules. 9, 11, 688.

Research output: Contribution to journalArticle

Open Access
ciclopirox
HSP90 Heat-Shock Proteins
Transcriptome
varespladib methyl
Gene expression

Genome organization and definition of the Penaeus monodon viral responsive protein 15 (PmVRP15) promoter

Jaree, P., Kawai, T., Lo, C-F., Tassanakajon, A. & Somboonwiwat, K., 2019 Oct 1, In : Fish and Shellfish Immunology. 93, p. 997-1006 10 p.

Research output: Contribution to journalArticle

Penaeus monodon
viral proteins
genome
Genes
promoter regions
Open Access
White spot syndrome virus 1
Hemocytes
Virus Replication
Glutamine
Genome
Open Access
Cell Cycle Proteins
Epithelial-Mesenchymal Transition
regulators
Prostatic Neoplasms
genes

Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis

Yen, C. J., Yang, S. T., Chen, R. Y., Huang, W., Chayama, K., Lee, M. H., Yang, S. J., Lai, H. S., Yen, H. Y., Hsiao, Y. W., Wang, J. M., Lin, Y. J. & Hung, L. Y., 2019 Jun 6, In : Journal of biomedical science. 26, 1, 44.

Research output: Contribution to journalArticle

Open Access
Proteins
Hepatocellular Carcinoma
Viruses
Hepatitis B virus
Cyclic AMP Response Element-Binding Protein
1 Citation (Scopus)

Hepatoma-derived growth factor supports the antiapoptosis and profibrosis of pancreatic stellate cells

Chen, Y. T., Chen, F. W., Chang, T. H., Wang, T. W., Hsu, T. P., Chi, J. Y., Hsiao, Y. W., Li, C. F. & Wang, J. M., 2019 Aug 10, In : Cancer Letters. 457, p. 180-190 11 p.

Research output: Contribution to journalArticle

Pancreatic Stellate Cells
Pancreatic Neoplasms
Hypoxia-Inducible Factor 1
Transforming Growth Factors
CCAAT-Enhancer-Binding Proteins

Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation

Wang, C. H., Hung, P. W., Chiang, C. W., Lombès, M., Chen, C. H., Lee, K. H., Lo, Y. C., Wu, M. H., Chang, W. C. & Lin, D. Y., 2019 Aug, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 8, p. 1282-1297 16 p.

Research output: Contribution to journalArticle

Mineralocorticoid Receptors
Ubiquitin
Catenins
Aldosterone
Transcriptional Activation
3 Citations (Scopus)

LvRas and LvRap are both important for WSSV replication in Litopenaeus vannamei

Tseng, Y. T., Kumar, R. & Wang, H-C., 2019 May 1, In : Fish and Shellfish Immunology. 88, p. 150-160 11 p.

Research output: Contribution to journalArticle

White spot syndrome virus
Litopenaeus vannamei
virus replication
Viruses
virus

Potassium Stimulation of IAA Transport Mediated by the Arabidopsis Importer AUX1 Investigated in a Heterologous Yeast System

Huang, L. K., Liao, Y. Y., Lin, W. H., Lin, S-M., Liu, T. Y., Lee, C. H. & Pan, R. L., 2019 Jun 15, In : Journal of Membrane Biology. 252, 2-3, p. 183-194 12 p.

Research output: Contribution to journalArticle

Indoleacetic Acids
Arabidopsis
Potassium
Yeasts
Gravitropism

Selective expression of a “correct cloud” of Dscam in crayfish survivors after second exposure to the same pathogen

Ng, T. H., Kumar, R., Apitanyasai, K., He, S. T., Chiu, S. P. & Wang, H. C., 2019 Sep, In : Fish and Shellfish Immunology. 92, p. 430-437 8 p.

Research output: Contribution to journalArticle

Down syndrome
Cell Adhesion Molecules
Pathogens
crayfish
adhesion
1 Citation (Scopus)

SlSWEET1a is involved in glucose import to young leaves in tomato plants

Ho, L. H., Klemens, P. A. W., Neuhaus, H. E., Ko, H. Y., Hsieh, S. Y. & Guo, W. J., 2019 Jun, In : Journal of experimental botany. 70, 12, p. 3241-3254 14 p.

Research output: Contribution to journalArticle

Open Access
Lycopersicon esculentum
imports
Cell Membrane
tomatoes
sugars

Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis

Hung, C. Y., Hsu, T. I., Chuang, J. Y., Su, T. P., Chang, W. C. & Hung, J-J., 2019 Jan 1, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Astrocytes
Synapses
Hippocampus
Neurons
Toll-Like Receptor 2
1 Citation (Scopus)

Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirAvp and pirBvp toxins and activation of the cry-like pore-forming domain

Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., 2019 Apr, In : Toxins. 11, 4, 233.

Research output: Contribution to journalArticle

Open Access
Vibrio parahaemolyticus
Penaeidae
Chemical activation
Necrosis
Hepatopancreas

The expression profile and prognostic significance of metallothionein genes in colorectal cancer

Hung, K. C., Huang, T. C., Cheng, C. H., Cheng, Y. W., Lin, D-Y., Fan, J. J. & Lee, K. H., 2019 Aug 2, In : International journal of molecular sciences. 20, 16, 3849.

Research output: Contribution to journalArticle

Open Access
Metallothionein
genes
Colorectal Neoplasms
Genes
cancer

The gene structure and hypervariability of the complete Penaeus monodon Dscam gene

Apitanyasai, K., Huang, S. W., Ng, T. H., He, S. T., Huang, Y. H., Chiu, S. P., Tseng, K. C., Lin, S. S., Chang, W. C., Baldwin-Brown, J. G., Long, A. D., Lo, C. F., Yu, H. T. & Wang, H. C., 2019 Dec 1, In : Scientific reports. 9, 1, 16595.

Research output: Contribution to journalArticle

Open Access
Penaeidae
Exons
Genes
Alternative Splicing
Tail
2018
2 Citations (Scopus)

Antibody profiling of kawasaki disease using Escherichia coli proteome microarrays

Kuo, H. C., Huang, Y. H., Chung, F. H., Chen, P. C., Sung, T. C., Chen, Y. W., Hsieh, K. S., Chen, C. S. & Syu, G. D., 2018 Mar, In : Molecular and Cellular Proteomics. 17, 3, p. 472-481 10 p.

Research output: Contribution to journalArticle

Mucocutaneous Lymph Node Syndrome
Proteome
Microarrays
Escherichia coli
Fever
4 Citations (Scopus)

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, Y-M., 2018 Jun, In : Redox Biology. 16, p. 104-112 9 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Oxidative stress
Reactive Oxygen Species
Astrocytes
Oxidative Stress
1 Citation (Scopus)
Genomics
Plasmids
Clone Cells
Escherichia coli
Cefixime
3 Citations (Scopus)

Complete genome sequence and phylogenetic analysis of megalocytivirus RSIV-Ku: A natural recombination infectious spleen and kidney necrosis virus

Shiu, J. Y., Hong, J-R., Ku, C. C. & Wen, C. M., 2018 Apr 1, In : Archives of Virology. 163, 4, p. 1037-1042 6 p.

Research output: Contribution to journalArticle

Iridoviridae
Trager duck spleen necrosis virus
Genetic Recombination
Sequence Analysis
Genome
17 Citations (Scopus)

Contrasting the relative importance of species sorting and dispersal limitation in shaping marine bacterial versus protist communities

Wu, W., Lu, H-P., Sastri, A., Yeh, Y. C., Gong, G. C., Chou, W. C. & Hsieh, C. H., 2018 Feb 1, In : ISME Journal. 12, 2, p. 485-494 10 p.

Research output: Contribution to journalArticle

Open Access
protist
Ribosomal DNA
sorting
Bacteria
organisms

Development of a computational promoter with highly efficient expression in tumors

Ho, S. Y., Chang, B. H., Chung, C. H., Lin, Y. L., Chuang, C. H., Hsieh, P. J., Huang, W. C., Tsai, N. M., Huang, S. C., Liu, Y. K., Lo, Y. C. & Liao, K. W., 2018 Apr 27, In : BMC cancer. 18, 1, 480.

Research output: Contribution to journalArticle

Transcription Factors
Computational Biology
Genetic Therapy
Neoplasms
Neoplasm Genes
2 Citations (Scopus)
Vibrio parahaemolyticus
Vietnam
Necrosis
Genome
Genes
1 Citation (Scopus)
Fresh Water
Taiwan
shrimp
Parasites
Nucleic Acid Databases

Functional characteristics of the flying squirrel's cecal microbiota under a leaf-based diet, based on multiple meta-omic profiling

Lu, H-P., Liu, P. Y., Wang, Y. B., Hsieh, J. F., Ho, H. C., Huang, S. W., Lin, C. Y., Hsieh, C. H. & Yu, H. T., 2018 Jan 4, In : Frontiers in Microbiology. 8, JAN, 2622.

Research output: Contribution to journalArticle

Open Access
Sciuridae
Microbiota
Herbivory
Diet
Genes
5 Citations (Scopus)

Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C. J., Ai, Y. L., Tsai, H. W., Chan, S. H., Yen, C. S., Cheng, K. H., Lee, Y. P., Kao, C. W., Wang, Y. C., Chen, Y. L., Lin, C. H., Liu, T., Tsai, H. P., Wang, J. R., Su, I. J. & Huang, W., 2018 Sep, In : Hepatology. 68, 3, p. 815-826 12 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Biomarkers
Recurrence
Surface Antigens

Measuring Ligand Binding Kinetics to Membrane Proteins Using Virion Nano-oscillators

Ma, G., Syu, G. D., Shan, X., Henson, B., Wang, S., Desai, P. J., Zhu, H. & Tao, N., 2018 Sep 12, In : Journal of the American Chemical Society. 140, 36, p. 11495-11501 7 p.

Research output: Contribution to journalArticle

Virion
Membrane Proteins
Ligands
Proteins
Membranes
3 Citations (Scopus)

Novel subunit vaccine with linear array epitope protect giant grouper against nervous necrosis virus infection

Lin, C. F., Jiang, H. K., Chen, N. C., Wang, T. Y. & Chen, T-Y., 2018 Mar 1, In : Fish and Shellfish Immunology. 74, p. 551-558 8 p.

Research output: Contribution to journalArticle

Subunit Vaccines
grouper
subunit vaccines
vaccine
Viruses
2 Citations (Scopus)

Nuclear targeting of the betanodavirus B1 protein via two arginine-rich domains induces G1/S cell cycle arrest mediated by upregulation of p53/p21

Su, Y. C., Reshi, L., Chen, L. J., Li, W. H., Chiu, H. W. & Hong, J-R., 2018 Dec 1, In : Scientific reports. 8, 1, 3079.

Research output: Contribution to journalArticle

Nodaviridae
G1 Phase Cell Cycle Checkpoints
Arginine
Cell Survival
Up-Regulation
4 Citations (Scopus)

Rap1 Negatively Regulates the Hippo Pathway to Polarize Directional Protrusions in Collective Cell Migration

Chang, Y. C., Wu, J. W., Hsieh, Y. C., Huang, T. H., Liao, Z. M., Huang, Y. S., Mondo, J. A., Montell, D. & Jang, A. C. C., 2018 Feb 20, In : Cell Reports. 22, 8, p. 2160-2175 16 p.

Research output: Contribution to journalArticle

Cell Movement
Actins
Cell Surface Extensions
Cues
Elongation
2 Citations (Scopus)
Exome
Frameshift Mutation
Mutation
Genes
Insulin Resistance
1 Citation (Scopus)

Role of Dicer in regulating oxaliplatin resistance of colon cancer cells

Lai, H. H., Lin, L. J., Hung, L. Y. & Chen, P. S., 2018 Nov 17, In : Biochemical and Biophysical Research Communications. 506, 1, p. 87-93 7 p.

Research output: Contribution to journalArticle

oxaliplatin
Colonic Neoplasms
Colorectal Neoplasms
Cells
Ubiquitin-Protein Ligases
3 Citations (Scopus)

Shrimp hemocyte homeostasis-associated protein (PmHHAP) interacts with WSSV134 to control apoptosis in white spot syndrome virus infection

Kantamas, A., Amparyup, P., Charoensapsri, W., Sangsuriya, P. & Tassanakajon, A., 2018 May 1, In : Fish and Shellfish Immunology. 76, p. 174-182 9 p.

Research output: Contribution to journalArticle

White spot syndrome virus
apoptosis
homeostasis
hemocytes
Viruses

The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes

Wang, Y. C., Chang, K-C., Lin, P-W., Lee, J-C., Lai, C. H., Lin, L. J., Yen, Y., Lin, C. S., Yang, S. J., Lin, P-C., Lee, C-T. & Hung, L-Y., 2018 Jun 1, In : Experimental and Molecular Medicine. 50, 6, 70.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
cdc Genes
Epidermal Growth Factor
Carcinogenesis
Genes
4 Citations (Scopus)

The Rho signalling pathway mediates the pathogenicity of AHPND-causing V. parahaemolyticus in shrimp

Ng, T. H., Lu, C. W., Lin, S. S., Chang, C. C., Tran, L. H., Chang, W-C., Lo, C-F. & Wang, H-C., 2018 Aug 1, In : Cellular Microbiology. 20, 8, e12849.

Research output: Contribution to journalArticle

Virulence
Necrosis
Hepatopancreas
Stomach
Genes
6 Citations (Scopus)

USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy

Wang, Y-C., Wu, Y. S., Hung, C. Y., Wang, S. A., Young, M. J., Hsu, T. I. & Hung, J-J., 2018 Dec 1, In : Nature communications. 9, 1, 3996.

Research output: Contribution to journalArticle

Tumor Microenvironment
Macrophages
Tumors
Interleukin-6
tumors
10 Citations (Scopus)

What vaccination studies tell us about immunological memory within the innate immune system of cultured shrimp and crayfish

Chang, Y. H., Kumar, R., Ng, T. H. & Wang, H. C., 2018 Mar, In : Developmental and Comparative Immunology. 80, p. 53-66 14 p.

Research output: Contribution to journalArticle

Immunologic Memory
Astacoidea
Immune System
Vaccination
Inactivated Vaccines
2017
23 Citations (Scopus)

Alpha-2-macroglobulin is a modulator of prophenoloxidase system in pacific white shrimp Litopenaeus vannamai

Ponprateep, S., Vatanavicharn, T., Lo, C-F., Tassanakajon, A. & Rimphanitchayakit, V., 2017 Mar 1, In : Fish and Shellfish Immunology. 62, p. 68-74 7 p.

Research output: Contribution to journalArticle

Litopenaeus
macroglobulins
alpha-Macroglobulins
prophenoloxidase
Modulators
6 Citations (Scopus)
Iridovirus
Mitochondria
Protein-Serine-Threonine Kinases
Cell death
mitochondrion
1 Citation (Scopus)

Betanodavirus B2 protein triggers apoptosis and necroptosis in lung cancer cells that suppresses autophagy

Chiu, H. W., Su, Y. C. & Hong, J. R., 2017 Nov 1, In : Oncotarget. 8, 55, p. 94129-94141 13 p.

Research output: Contribution to journalArticle

Nodaviridae
Autophagy
Lung Neoplasms
Apoptosis
Mitochondria
2 Citations (Scopus)

Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia

Chu, Y., Ko, C., Wang, S., Lin, P., Wang, H., Lin, W., Wu, D., Wang, L. & Wang, Y-M., 2017, In : Cell Death and Disease. 8, 11, p. e3167

Research output: Contribution to journalArticle

CCAAT/enhancer-binding protein delta promotes intracellular lipid accumulation in M1 macrophages of vascular lesions

Lai, H., Hsu, L., Tsai, H., Lo, Y., Yang, S., Liu, P. & Wang, Y-M., 2017 Sep 1, In : Cardiovascular Research. 113, 11, p. 1376-1388

Research output: Contribution to journalArticle

4 Citations (Scopus)

CCAAT/enhancer-binding protein delta promotes intracellular lipid accumulation in M1 macrophages of vascular lesions

Lai, H. Y., Hsu, L. W., Tsai, H. H., Lo, Y-C., Yang, S-H., Liu, P-Y. & Wang, J-M., 2017 Jan 1, In : Cardiovascular Research. 113, 11, p. 1376-1388 13 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Blood Vessels
Macrophages
Lipids
Apolipoproteins E
3 Citations (Scopus)

Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways

Su, W-P., Ho, Y. C., Wu, C. K., Hsu, S. H., Shiu, J. L., Huang, J. C., Chang, S-B., Chiu, W-T., Hung, J-J., Liu, T., Wu, W-S., Wu, P. Y., Su, W-C., Chang, J-Y. & Liaw, H-J., 2017 Dec 1, In : Scientific reports. 7, 1, 3879.

Research output: Contribution to journalArticle

Fanconi Anemia
Recombinational DNA Repair
Cisplatin
Fanconi Anemia Complementation Group D2 Protein
Genes
13 Citations (Scopus)

Comparative genomics of Vibrio campbellii strains and core species of the Vibrio Harveyi clade

Ke, H. M., Prachumwat, A., Yu, C. P., Yang, Y. T., Promsri, S., Liu, K. F., Lo, C. F., Lu, M. Y. J., Lai, M. C., Tsai, I. J. & Li, W. H., 2017 Feb 1, In : Scientific reports. 7, 41394.

Research output: Contribution to journalArticle

Vibrio
Genomics
Genes
Bacterial Genes
Immunoglobulin Genes