Department of Food Safety / Hygiene and Risk Management

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P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment

Chen, R. J., Wu, P. H., Ho, C. T., Way, T. D., Pan, M. H., Chen, H. M., Ho, Y. S. & Wang, Y. J., 2017 Aug 10, In : Cell death & disease. 8, 8, p. e2985

Research output: Contribution to journalArticle

19 Citations (Scopus)

Oxidative damage of workers in secondary metal recovery plants affected by smoking status and joining the smelting work

Chia, T., Hsu, C. Y. & Chen, H-L., 2008 Mar 1, In : Industrial Health. 46, 2, p. 174-182 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
4 Citations (Scopus)

Oxidative damage in foundry workers occupationally co-exposed to PAHs and metals

Liu, H. H., Lin, M. H., Chan, C. I. & Chen, H-L., 2010 Mar 1, In : International Journal of Hygiene and Environmental Health. 213, 2, p. 93-98 6 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Overview of protein microarrays

Sutandy, F. X. R., Qian, J., Chen, C. S. & Zhu, H., 2013 Sep 3, In : Current Protocols in Protein Science. SUPPL.72, 27.1.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Optimization of the enzymic process for manufacturing low-lactose milk containing oligosaccharides

Chen, C. S., Hsu, C. K. & Chiang, B. H., 2002 Dec 31, In : Process Biochemistry. 38, 5, p. 801-808 8 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Optimization of DNA-directed immobilization on mixed oligo(ethylene glycol) monolayers for immunodetection

Hu, W. P., Huang, L. Y., Kuo, T. C., Hu, W. W., Chang, Y., Chen, C. S., Chen, H. C. & Chen, W. Y., 2012 Apr 1, In : Analytical Biochemistry. 423, 1, p. 26-35 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Optimal conditions for cordycepin production in surface liquid-cultured Cordyceps militaris treated with porcine liver extracts for suppression of oral cancer

Lin, L. T., Lai, Y. J., Wu, S. C., Hsu, W. H. & Tai, C. J., 2018 Jan, In : Journal of Food and Drug Analysis. 26, 1, p. 135-144 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Occupational exposure and DNA strand breakage of workers in bottom ash recovery and fly ash treatment plants

Chen, H. L., Chen, I. J. & Chia, T. P., 2010 Feb 15, In : Journal of Hazardous Materials. 174, 1-3, p. 23-27 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Nε-lysine acetylation of a bacterial transcription factor inhibits its DNA-binding activity

Thao, S., Chen, C. S., Zhu, H. & Escalante-Semerena, J. C., 2010 Dec 1, In : PloS one. 5, 12, e15123.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Nitride-Based Microarray Biochips: A New Route of Plasmonic Imaging

Chien, F. C., Lo, J. L., Zhang, X., Cubukcu, E., Luo, Y. T., Huang, K. L., Tang, X., Chen, C. S., Chen, C. C. & Lai, K. Y., 2018 Nov 21, In : ACS Applied Materials and Interfaces. 10, 46, p. 39898-39903 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

NF-κB-activated tissue transglutaminase is involved in ethanol-induced hepatic injury and the possible role of propolis in preventing fibrogenesis

Chen, C. S., Wu, C. H., Lai, Y. C., Lee, W. S., Chen, H. M., Chen, R. J., Chen, L. C., Ho, Y. S. & Wang, Y. J., 2008 Apr 18, In : Toxicology. 246, 2-3, p. 148-157 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species

Wang, B. J., Guo, Y. L., Chang, H. Y., Sheu, H. M., Pan, M. H., Lee, Y. H. & Wang, Y. J., 2010 Aug 1, In : Experimental Dermatology. 19, 8, p. e191-e200

Research output: Contribution to journalArticle

16 Citations (Scopus)

N-acetylcysteine attenuates hexavalent chromium-induced hypersensitivity through inhibition of cell death, ROS-related signaling and cytokine expression

Lee, Y. H., Su, S. B., Huang, C. C., Sheu, H. M., Tsai, J. C., Lin, C. H., Wang, Y. J. & Wang, B. J., 2014 Sep 23, In : PloS one. 9, 9, e108317.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Monascus secondary metabolites monascin and ankaflavin inhibit activation of RBL-2H3 Cells

Chang, Y. Y., Hsu, W-H. & Pan, T. M., 2015 Jan 14, In : Journal of Agricultural and Food Chemistry. 63, 1, p. 192-199 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Monascuspiloin induces apoptosis and autophagic cell death in human prostate cancer cells via the akt and AMPK signaling pathways

Chen, R-J., Hung, C. M., Chen, Y. L., Wu, M. D., Yuan, G. F. & Wang, Y-J., 2012 Jul 25, In : Journal of Agricultural and Food Chemistry. 60, 29, p. 7185-7193 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Monascus-fermented metabolite monascin suppresses inflammation via PPAR-γ regulation and JNK inactivation in THP-1 monocytes

Hsu, W. H., Lee, B. H., Liao, T. H., Hsu, Y. W. & Pan, T. M., 2012 May 1, In : Food and Chemical Toxicology. 50, 5, p. 1178-1186 9 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Monascin improves diabetes and dyslipidemia by regulating PPARγ and inhibiting lipogenesis in fructose-rich diet-induced C57BL/6 mice

Lee, B. H., Hsu, W. H., Huang, T., Chang, Y. Y., Hsu, Y. W. & Pan, T. M., 2013 Jun, In : Food and Function. 4, 6, p. 950-959 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
20 Citations (Scopus)

Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice

Hsu, W-H., Chen, T. H., Lee, B. H., Hsu, Y. W. & Pan, T. M., 2014 Jan 1, In : Food and Chemical Toxicology. 64, p. 94-103 10 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)
15 Citations (Scopus)

Monacolin K and monascin attenuated pancreas impairment and hyperglycemia induced by advanced glycation endproducts in BALB/c mice

Hsu, W-H., Lu, S. S., Lee, B. H., Hsu, Y. W. & Pan, T. M., 2013 Dec 1, In : Food and Function. 4, 12, p. 1742-1750 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Modification of silicone elastomer with zwitterionic silane for durable antifouling properties

Yeh, S. B., Chen, C-S., Chen, W. Y. & Huang, C. J., 2014 Sep 30, In : Langmuir. 30, 38, p. 11386-11393 8 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Miracle fruit (Synsepalum dulcificum) exhibits as a novel anti-hyperuricaemia agent

Shi, Y. C., Lin, K. S., Jhai, Y. F., Lee, B. H., Han, Y., Cui, Z., Hsu, W. H. & Wu, S. C., 2016 Feb, In : Molecules. 21, 2, 140.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Mechanisms of apoptosis induction and cell cycle regulation in irradiated leukemia U937 cells and enhancement by arsenic trioxide

Ho, S. Y., Huang, P. C., Guo, H-R., Chang, W. H., Chen, R-J., Wei, B. L., Wu, W. J., Tai, C. & Wang, Y-J., 2006 Apr 1, In : Radiation Research. 165, 4, p. 390-399 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
55 Citations (Scopus)

Liposome encapsulation of fluorescent nanoparticles: Quantum dots and silica nanoparticles

Chen, C. S., Yao, J. & Durst, R. A., 2006 Dec 1, In : Journal of Nanoparticle Research. 8, 6, p. 1033-1038 6 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Lipid peroxidation and oxidative status compared in workers at a bottom ash recovery plant and fly ash treatment plants

Liu, H. H., Shih, T. S., Chen, I. J. & Chen, H. L., 2008 Dec 1, In : Journal of Occupational Health. 50, 6, p. 492-497 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Lipid peroxidation and antioxidant status in workers exposed to PCDD/Fs of metal recovery plants

Chen, H. L., Hsu, C. Y., Hung, D. Z. & Hu, M. L., 2006 Dec 15, In : Science of the Total Environment. 372, 1, p. 12-19 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Leptin-induced mitochondrial fusion mediates hepatic lipid accumulation

Hsu, W. H., Lee, B. H. & Pan, T. M., 2015 Dec 1, In : International Journal of Obesity. 39, 12, p. 1750-1756 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Lactoferricin B inhibits the phosphorylation of the two-component system response regulators BasR and CreB

Ho, Y. H., Sung, T. C. & Chen, C. S., 2012 Apr 1, In : Molecular and Cellular Proteomics. 11, 4

Research output: Contribution to journalArticle

28 Citations (Scopus)

Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice

Wang, Y. J., Jeng, J. H., Chen, R. J., Tseng, H., Chen, L. C., Liang, Y. C., Lin, C. H., Chen, C. H., Chu, J. S., Ho, W. L. & Ho, Y. S., 2002 Aug 14, In : Molecular Carcinogenesis. 34, 4, p. 199-210 12 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Ketoconazole induces G0/G1 arrest in human colorectal and hepatocellular carcinoma cell lines

Chen, R. J., Lee, W. S., Liang, Y. C., Lin, J. K., Wang, Y. J., Lin, C. H., Hsieh, J. Y., Chaing, C. C. & Ho, Y. S., 2000 Dec 1, In : Toxicology and Applied Pharmacology. 169, 2, p. 132-141 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Ketoconazole-induced apoptosis through P53-dependent pathway in human colorectal and hepatocellular carcinoma cell lines

Ho, Y. S., Tsai, P. W., Yu, C. F., Liu, H. L., Chen, R. J. & Lin, J. K., 1998 Nov, In : Toxicology and Applied Pharmacology. 153, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

In vitro and in vivo studies of the anticancer action of terbinafine in human cancer cell lines: G0/G1 p53-associated cell cycle arrest

Lee, W. S., Chen, R-J., Wang, Y-J., Tseng, H., Jeng, J. H., Lin, S. Y., Liang, Y. C., Chen, C. H., Lin, C. H., Lin, J. K., Ho, P. Y., Chu, J. S., Ho, W. L., Chen, L. C. & Ho, Y. S., 2003 Aug 10, In : International Journal of Cancer. 106, 1, p. 125-137 13 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

In vitro and in vivo anticancer activity of pardaxin against proliferation and growth of oral squamous cell carcinoma

Han, Y., Cui, Z., Li, Y. H., Hsu, W. H. & Lee, B. H., 2016 Jan, In : Marine Drugs. 14, 1, 2.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Intestinal fungi contribute to development of alcoholic liver disease

Yang, A. M., Inamine, T., Hochrath, K., Chen, P., Wang, L., Llorente, C., Bluemel, S., Hartmann, P., Xu, J., Koyama, Y., Kisseleva, T., Torralba, M. G., Moncera, K., Beeri, K., Chen, C. S., Freese, K., Hellerbrand, C., Lee, S. M. L., Hoffman, H. M., Mehal, W. Z. & 9 others, Garcia-Tsao, G., Mutlu, E. A., Keshavarzian, A., Brown, G. D., Ho, S. B., Bataller, R., Stärkel, P., Fouts, D. E. & Schnabl, B., 2017 Jun 30, In : Journal of Clinical Investigation. 127, 7, p. 2829-2841 13 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)
20 Citations (Scopus)

Interleukin 10 promoter haplotype is associated with alcoholic liver cirrhosis in Taiwanese patients

Yang, A. M., Wen, L. L., Yang, C. S., Wang, S. C., Chen, C. S. & Bair, M. J., 2014 Jun, In : Kaohsiung Journal of Medical Sciences. 30, 6, p. 291-298 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2 Citations (Scopus)

Inhibitory effects of dioscorea polysaccharide on TNF-α-induced insulin resistance in mouse FL83B cells

Lee, B. H., Hsu, W-H. & Pan, T. M., 2011 May 25, In : Journal of Agricultural and Food Chemistry. 59, 10, p. 5279-5285 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Inhibition of Th2 cytokine production in T cells by monascin via PPAR-γ activation

Hsu, W. H., Lee, B. H., Hsu, Y. W. & Pan, T. M., 2013 Aug 28, In : Journal of Agricultural and Food Chemistry. 61, 34, p. 8126-8133 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Inhibition of leukemia proliferation by a novel polysaccharide identified from Monascus-fermented dioscorea via inducing differentiation

Lee, B. H., Hsu, W-H., Liao, T. H. & Pan, T. M., 2012 Jul 1, In : Food and Function. 3, 7, p. 758-764 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Influences of beehive firework displays on ambient fine particles during the lantern festival in the YanShuei area of Southern Taiwan

Lin, C. C., Huang, K. L., Chen, H. L., Tsai, J. H., Chiu, Y. P., Lee, J. T. & Chen, S. J., 2014 Dec 1, In : Aerosol and Air Quality Research. 14, 7, p. 1998-2009 12 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Induction of Autophagy by Pterostilbene Contributes to the Prevention of Renal Fibrosis via Attenuating NLRP3 Inflammasome Activation and Epithelial-Mesenchymal Transition

Wang, Y. J., Chen, Y. Y., Hsiao, C. M., Pan, M. H., Wang, B. J., Chen, Y. C., Ho, C. T., Huang, K. C. & Chen, R. J., 2020 Jun 3, In : Frontiers in Cell and Developmental Biology. 8, 436.

Research output: Contribution to journalArticle

Open Access

Induction of apoptosis by S-nitrosoglutathione and Cu2+ or Ni2+ ion through modulation of bax, bad, and bcl-2 proteins in human colon adenocarcinoma cells

Ho, Y. S., Liu, H. L., Duh, J. S., Chen, R-J., Ho, W. L., Jeng, J. H., Wang, Y-J. & Lin, J. K., 1999 Nov 22, In : Molecular Carcinogenesis. 26, 3, p. 201-211 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Indium Acetate Toxicity in Male Reproductive System in Rats

Lee, K. H., Chen, H-L., Leung, C. M., Chen, H. P. & Hsu, P. C., 2016 Jan 1, In : Environmental Toxicology. 31, 1, p. 68-76 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Immunomodulatory and antioxidant potential of Lactobacillus exopolysaccharides

Liu, C. F., Tseng, K. C., Chiang, S. S., Lee, B. H., Hsu, W-H. & Pan, T. M., 2011 Sep 1, In : Journal of the Science of Food and Agriculture. 91, 12, p. 2284-2291 8 p.

Research output: Contribution to journalArticle

122 Citations (Scopus)

Identification of novel serological biomarkers for inflammatory bowel disease using Escherichia coli proteome chip

Chen, C. S., Sullivan, S., Anderson, T., Tan, A. C., Alex, P. J., Brant, S. R., Cuffari, C., Bayless, T. M., Talor, M. V., Burek, C. L., Wang, H., Li, R., Datta, L. W., Wu, Y., Winslow, R. L., Zhu, H. & Li, X., 2009 Dec 8, In : Molecular and Cellular Proteomics. 8, 8, p. 1765-1776 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Identification of lactoferricin B intracellular targets using an escherichia coli proteome chip

Tu, Y. H., Ho, Y. H., Chuang, Y. C., Chen, P. C. & Chen, C. S., 2011 Dec 2, In : PloS one. 6, 12, e28197.

Research output: Contribution to journalArticle

25 Citations (Scopus)