Department of Internal Medicine

Research Output 1987 2019

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Review article
2019

A performance guide for major risk factors control in patients with atherosclerotic cardiovascular disease in Taiwan

Li, Y-H., Chen, J. W., Lin, T. H., Wang, Y. C., Wu, C. C., Yeh, H. I., Huang, C. C., Chang, K. C., Wu, C. K., Chen, P-W., Huang, C-W., Chen, Z. C., Chang, W. T., Huang, W. C., Wang, C. Y., Lee, M. Y., Chao, A. C., Fu, W. R., Tsai, L. K., Tang, S. C. & 5 others, Chan, H. L., Yang, Y-C., Wu, Y. W., Hwang, J. J. & Lin, J. L., 2019 Jan 1, In : Journal of the Formosan Medical Association.

Research output: Contribution to journalReview article

Open Access
Taiwan
Cardiovascular Diseases
Cerebrovascular Disorders
Peripheral Arterial Disease
Hypercholesterolemia

Bortezomib therapy in a real-world setting in patients with relapsed or refractory multiple myeloma

Huang, S. Y., Chen, T-Y., Kuo, C. Y., Chen, Y. C., Lin, S. F., Chang, M. C., Lv, X., Yang, B. & Chang, C. S., 2019 Jan 14, In : Oncology Reviews. 13, 1, p. 15-22 8 p.

Research output: Contribution to journalReview article

Open Access
Multiple Myeloma
Therapeutics
Bortezomib
Safety
Proteasome Inhibitors

Dialysis therapy: Concept evolution and update

Kuo, Y. T., Lee, C-C. & Sung, J-M., 2019 Apr 1, In : Journal of Internal Medicine of Taiwan. 30, 2, p. 86-95 10 p.

Research output: Contribution to journalReview article

Peritoneal Dialysis
Renal Dialysis
Dialysis
Dialysis Solutions
Quality of Life

Store-Operated Ca2+ entry in tumor progression: From molecular mechanisms to clinical implications

Chen, Y. F., Lin, P-C., Yeh, Y. M., Chen, L. H. & Shen, M-R., 2019 Jul 1, In : Cancers. 11, 7, 899.

Research output: Contribution to journalReview article

Open Access
Neoplasms
Endoplasmic Reticulum
Neoplasm Metastasis
Cellular Microenvironment
Tumor Microenvironment
Head and Neck Neoplasms
Alcohols
Surveys and Questionnaires
Alleles
Validation Studies
2018
2 Citations (Scopus)

2018 expert consensus on the management of adverse effects of antiplatelet therapy for acute coronary syndrome in Taiwan

Li, Y-H., Fang, C. Y., Hsieh, I. C., Huang, W. C., Lin, T. H., Sung, S. H., Chiu, C. Z., Wu, C. J., Shyu, K. G., Chang, P. Y., Fang, C. C., Lu, T. M., Chen, C. P., Tai, W. C., Sheu, C. C., Wei, K. C., Huang, Y. H., Wu, H. M. & Hwang, J. J., 2018 May 1, In : Acta Cardiologica Sinica. 34, 3, p. 201-210 10 p.

Research output: Contribution to journalReview article

Acute Coronary Syndrome
Taiwan
Platelet Aggregation Inhibitors
Ecchymosis
Hemorrhage
3 Citations (Scopus)
Satellite Viruses
Viruses
Hepatitis B virus
Hepatocellular Carcinoma
Nucleotides
2 Citations (Scopus)

Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan?

Lu, P. L., Liu, W. L., Lo, H. J., Wang, F. D., Ko, W-C., Hsueh, P. R., Ho, M. W., Liu, C. E., Chen, Y. H., Chen, Y. C., Chuang, Y. C. & Chang, S. C., 2018 Jun 1, In : Journal of the Formosan Medical Association. 117, 6, p. 462-470 9 p.

Research output: Contribution to journalReview article

Taiwan
Candida
Disease Outbreaks
Delivery of Health Care
Hospital Laboratories

Comparison of the 2017 Taiwan lipid guidelines and the Western lipid guidelines for high risk patients

Li, Y-H., Yeh, H. I., Jeng, J. S. & Charng, M. J., 2018 Oct 1, In : Journal of the Chinese Medical Association. 81, 10, p. 853-859 7 p.

Research output: Contribution to journalReview article

Taiwan
Guidelines
Lipids
Cardiovascular Diseases
Dyslipidemias
1 Citation (Scopus)
Acute Coronary Syndrome
Taiwan
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Coronary Artery Disease
Guidelines
4 Citations (Scopus)

The impacts of H. pylori virulence factors on the development of gastroduodenal diseases

Chang, W-L., Yeh, Y. C. & Sheu, B-S., 2018 Sep 11, In : Journal of biomedical science. 25, 1, 68.

Research output: Contribution to journalReview article

Pylorus
Virulence Factors
Stomach
Genes
Cytotoxins
6 Citations (Scopus)

Therapeutic opportunities of targeting histone deacetylase isoforms to eradicate cancer stem cells

Lin, P-C., Hsieh, H. Y., Chu, P. C. & Chen, C. S., 2018 Jul 2, In : International journal of molecular sciences. 19, 7, 1939.

Research output: Contribution to journalReview article

Histone Deacetylases
Neoplastic Stem Cells
stem cells
Stem cells
Protein Isoforms
4 Citations (Scopus)

The Taiwan Heart Registries: Its Influence on Cardiovascular Patient Care

Wu, C. K., Juang, J. M. J., Chiang, J. Y., Li, Y-H., Tsai, C. T. & Chiang, F. T., 2018 Mar 20, In : Journal of the American College of Cardiology. 71, 11, p. 1273-1283 11 p.

Research output: Contribution to journalReview article

National Health Programs
Patient Education
Taiwan
Registries
Patient Care
2017
40 Citations (Scopus)

2017 Taiwan lipid guidelines for high risk patients

The Writing Group of 2017 Taiwan Lipid Guidelines for High Risk Patients, 2017 Apr 1, In : Journal of the Formosan Medical Association. 116, 4, p. 217-248 32 p.

Research output: Contribution to journalReview article

Taiwan
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Guidelines
Lipids
Hyperlipoproteinemia Type II
3 Citations (Scopus)

Role of rifampin for the treatment of bacterial infections other than mycobacteriosis

Lee, C. Y., Huang, C. H., Lu, P. L., Ko, W-C., Chen, Y. H. & Hsueh, P. R., 2017 Nov 1, In : Journal of Infection. 75, 5, p. 395-408 14 p.

Research output: Contribution to journalReview article

Rifampin
Bacterial Infections
Infection
Bacteremia
Endocarditis
8 Citations (Scopus)

Treatment of Pneumocystis jirovecii pneumonia in HIV-infected patients: a review

Huang, Y. S., Yang, J. J., Lee, N-Y., Chen, G. J., Ko, W-C., Sun, H. Y. & Hung, C. C., 2017 Sep 2, In : Expert Review of Anti-Infective Therapy. 15, 9, p. 873-892 20 p.

Research output: Contribution to journalReview article

Pneumocystis carinii
Pneumocystis Pneumonia
HIV
Sulfamethoxazole Drug Combination Trimethoprim
Dihydropteroate Synthase
2016
17 Citations (Scopus)

Aeromonas dhakensis, an increasingly recognized human pathogen

Chen, P-L., Lamy, B. & Ko, W-C., 2016 Jan 1, In : Frontiers in Microbiology. 7, MAY, 793.

Research output: Contribution to journalReview article

Aeromonas
Bacteremia
Virulence
Virulence Factors
Infection
7 Citations (Scopus)

Development of nanoliposomal irinotecan (nal-IRI, MM-398, PEP02) in the management of metastatic pancreatic cancer

Chiang, N. J., Chang, J-Y., Shan, Y-S. & Chen, L. T., 2016 Jul 2, In : Expert Opinion on Pharmacotherapy. 17, 10, p. 1413-1420 8 p.

Research output: Contribution to journalReview article

irinotecan
gemcitabine
Leucovorin
Pancreatic Neoplasms
Fluorouracil
80 Citations (Scopus)

Helicobacter pylori infection: An overview of bacterial virulence factors and pathogenesis

Kao, C. Y., Sheu, B-S. & Wu, J. J., 2016 Jan 1, In : Biomedical Journal. 39, 1, p. 14-23 10 p.

Research output: Contribution to journalReview article

Helicobacter Infections
Virulence Factors
Helicobacter pylori
Stomach
Bacterial Adhesins
5 Citations (Scopus)

Recent developments in antibiotic agents for the treatment of complicated intra-abdominal infections

Lin, S. Y., Huang, C. H., Ko, W-C., Chen, Y. H. & Hsueh, P. R., 2016 Feb 11, In : Expert Opinion on Pharmacotherapy. 17, 3, p. 339-354 16 p.

Research output: Contribution to journalReview article

Intraabdominal Infections
Anti-Bacterial Agents
Therapeutics
Quinolones
Aminoglycosides
7 Citations (Scopus)

Salmonella infective endocarditis

Cheng, W. L., Li, C-W., Li, M-C., Lee, N-Y., Lee, C. C. & Ko, W-C., 2016 Jun 1, In : Journal of Microbiology, Immunology and Infection. 49, 3, p. 313-320 8 p.

Research output: Contribution to journalReview article

Endocarditis
Salmonella
Abscess
Literature
Bacterial Endocarditis
26 Citations (Scopus)

The emerging landscape of salivary diagnostics

Zhang, Y., Sun, J., Lin, C-C., Abemayor, E., Wang, M. B. & Wong, D. T. W., 2016 Feb 1, In : Periodontology 2000. 70, 1, p. 38-52 15 p.

Research output: Contribution to journalReview article

Saliva
Biomarkers
Untranslated RNA
Metabolomics
Microbiota
22 Citations (Scopus)

The Role of Wnt Signaling in Squamous Cell Carcinoma

Shiah, S. G., Shieh, Y. S. & Chang, J-Y., 2016 Feb 1, In : Journal of Dental Research. 95, 2, p. 129-134 6 p.

Research output: Contribution to journalReview article

Wnt Signaling Pathway
Squamous Cell Carcinoma
MicroRNAs
Catenins
Neoplasms
1 Citation (Scopus)

Viral Hepatitis and Diabetes: Clinical Implications of Diabetes Prevention Through Hepatitis Vaccination

Karnchanasorn, R., Ou, H-Y., Lin, J., Chuang, L. M. & Chiu, K. C., 2016 Oct 1, In : Current Diabetes Reports. 16, 10, 101.

Research output: Contribution to journalReview article

Hepatitis
Vaccination
Hepatitis B
Type 2 Diabetes Mellitus
Costs and Cost Analysis
2015
27 Citations (Scopus)

Clinical impact of Clostridium difficile colonization

Hung, Y. P., Lee, J-C., Lin, H-J., Liu, H. C., Wu, Y. H., Tsai, P-J. & Ko, W-C., 2015 Jun 1, In : Journal of Microbiology, Immunology and Infection. 48, 3, p. 241-248 8 p.

Research output: Contribution to journalReview article

Clostridium difficile
Diarrhea
Hand Disinfection
Skin
Toll-Like Receptor 4
11 Citations (Scopus)

Doxycycline and tigecycline: Two friendly drugs with a low association with Clostridium difficile infection

Hung, Y. P., Lee, J-C., Lin, H-J., Liu, H. C., Wu, Y. H., Tsai, P-J. & Ko, W-C., 2015 Jun 19, In : Antibiotics. 4, 2, p. 216-229 14 p.

Research output: Contribution to journalReview article

Clostridium Infections
Clostridium
Clostridium difficile
Doxycycline
Tetracycline
19 Citations (Scopus)

Emerging platforms using liquid biopsy to detect EGFR mutations in lung cancer

Lin, C-C., Huang, W. L., Wei, F., Su, W-C. & Wong, D. T., 2015 Nov 2, In : Expert Review of Molecular Diagnostics. 15, 11, p. 1427-1440 14 p.

Research output: Contribution to journalReview article

Lung Neoplasms
Biopsy
Mutation
Neoplasms
Hematologic Tests
Severe Acute Respiratory Syndrome
Extracorporeal Membrane Oxygenation
Adult Respiratory Distress Syndrome
Human Influenza
Pregnant Women
4 Citations (Scopus)

The role of echocardiographic study in patients with chronic kidney disease

Liu, Y-W., Su, C. T., Song, E. J., Tsai, W-C., Li, Y-H., Tsai, L-M., Chen, J. H. & Sung, J-M., 2015 Sep 1, In : Journal of the Formosan Medical Association. 114, 9, p. 797-805 9 p.

Research output: Contribution to journalReview article

Chronic Renal Insufficiency
Mortality
Morbidity
Left Ventricular Function
Cardiovascular Diseases
2014
7 Citations (Scopus)

2014 guidelines of taiwan society of cardiology (TSOC) for the management of pulmonary arterial hypertension

Hsu, C-H., Ho, W. J., Huang, W. C., Chiu, Y. W., Hsu, T. S., Kuo, P. H., Hsu, H. H., Chang, J. K., Cheng, C. C., Lai, C. L., Liang, K. W., Lin, S. L., Sung, S. H., Tsai, W-C., Weng, K. P., Hsieh, K. S., Yin, W. H., Lin, S. J. & Wang, K. Y., 2014 Sep 1, In : Acta Cardiologica Sinica. 30, 5, p. 401-444 44 p.

Research output: Contribution to journalReview article

Cardiology
Taiwan
Pulmonary Hypertension
Guidelines
Lung
35 Citations (Scopus)

Achieving glycemic control in elderly patients with type 2 diabetes: A critical comparison of current options

Du, Y-F., Ou, H-Y., Beverly, E. A. & Chiu, C-J., 2014 Nov 18, In : Clinical Interventions in Aging. 9, p. 1963-1980 18 p.

Research output: Contribution to journalReview article

Type 2 Diabetes Mellitus
Guidelines
Life Expectancy
Hypoglycemia
Hypoglycemic Agents

Diagnosis and treatment of bronchiectasis, clinical review

Han, M. Z. & Chang, H-Y., 2014 Jan 1, In : Journal of Internal Medicine of Taiwan. 25, 3, p. 176-183 8 p.

Research output: Contribution to journalReview article

Bronchiectasis
Fibrosis
Bacteria
Microbiology
Therapeutics
6 Citations (Scopus)

Pluripotent stem cell therapy in ischemic cardiovascular disease

Chao, T-H., Chen, I. C., Tseng, S. Y. & Li, Y-H., 2014 Sep 1, In : Acta Cardiologica Sinica. 30, 5, p. 365-374 10 p.

Research output: Contribution to journalReview article

Pluripotent Stem Cells
Cell- and Tissue-Based Therapy
Cardiovascular Diseases
Stem Cells
Induced Pluripotent Stem Cells
2 Citations (Scopus)

Pneumomediastinum in patients with AIDS: A case report and literature review

Cheng, W. L., Ko, W-C., Lee, N-Y., Chang, C-M., Lee, C. C., Li, M-C. & Li, C-W., 2014 Jan 1, In : International Journal of Infectious Diseases. 22, p. 31-34 4 p.

Research output: Contribution to journalReview article

Mediastinal Emphysema
Acquired Immunodeficiency Syndrome
HIV
Pneumocystis carinii
Pneumonia
Positive-Pressure Respiration
Adult Respiratory Distress Syndrome
Tidal Volume
Lung Injury
Mechanical Ventilators
15 Citations (Scopus)

Trends in the susceptibility of methicillin-resistant Staphylococcus aureus to nine antimicrobial agents, including ceftobiprole, nemonoxacin, and tyrothricin: Results from the Tigecycline in Vitro Surveillance in Taiwan (TIST) study, 2006-2010

Chen, Y. H., Liu, C. Y., Ko, W-C., Liao, C. H., Lu, P. L., Huang, C. H., Lu, C. T., Chuang, Y. C., Tsao, S. M., Chen, Y. S., Liu, Y. C., Chen, W. Y., Jang, T. N., Lin, H. C., Chen, C. M., Shi, Z. Y., Pan, S. C., Yang, J. L., Kung, H. C., Liu, C. E. & 10 others, Cheng, Y. J., Liu, J. W., Sun, W., Wang, L. S., Yu, K. W., Chiang, P. C., Lee, M. H., Lee, C. M., Hsu, G. J. & Hsueh, P. R., 2014 Feb 1, In : European Journal of Clinical Microbiology and Infectious Diseases. 33, 2, p. 233-239 7 p.

Research output: Contribution to journalReview article

Tyrothricin
Microbial Sensitivity Tests
Methicillin-Resistant Staphylococcus aureus
Anti-Infective Agents
Taiwan
8 Citations (Scopus)

What could be changed in the 2012 Taiwan ST-segment elevation myocardial infarction guideline?

Li, Y-H., Hsieh, I. C., Shyu, K. G. & Kuo, F. Y., 2014 Sep 1, In : Acta Cardiologica Sinica. 30, 5, p. 360-364 5 p.

Research output: Contribution to journalReview article

Percutaneous Coronary Intervention
Taiwan
Guidelines
Thrombectomy
Drug-Eluting Stents
2013
22 Citations (Scopus)

Emerging resistance problems and future perspectives in pharmacotherapy for complicated urinary tract infections

Chen, Y. H., Ko, W-C. & Hsueh, P. R., 2013 Apr 1, In : Expert Opinion on Pharmacotherapy. 14, 5, p. 587-596 10 p.

Research output: Contribution to journalReview article

Urinary Tract Infections
Drug Therapy
Linezolid
Polymyxins
Daptomycin
77 Citations (Scopus)

Survivin - biology and potential as a therapeutic target in oncology

Cheung, C-H., Huang, C. C., Tsai, F. Y., Lee, J. Y. C., Cheng, S. M., Chang, Y. C., Huang, Y. C., Chen, S. H. & Chang, J-Y., 2013 Oct 28, In : OncoTargets and Therapy. 6, p. 1453-1462 10 p.

Research output: Contribution to journalReview article

Inhibitor of Apoptosis Proteins
Post Translational Protein Processing
Acetylation
Drug Resistance
PubMed
6 Citations (Scopus)

Treatment of extensively drug-resistant Gram-negative infections in critically ill patients: Outcome of a consensus meeting at the 13th Asia-Pacific Congress of Clinical Microbiology and Infection, October 2012

Tambyah, P. A., Hara, G. L., Daikos, G. L., Falagas, M. E., Mazzei, T., Mouton, J. W., Novelli, A., Chen, B., Wang, M., Ko, W-C., Li, T., Fan, X. & Theuretzbacher, U., 2013 Aug 26, In : Journal of Global Antimicrobial Resistance. 1, 3, p. 117-122 6 p.

Research output: Contribution to journalReview article

Microbiology
Critical Illness
Infection
Pharmaceutical Preparations
Long-Term Care
2012
25 Citations (Scopus)

2012 Guidelines of the Taiwan Society of Cardiology (TSOC) for the management of ST-segment elevation myocardial infarction

Li, Y-H., Yeh, H. I., Tsai, C. T., Liu, P-Y., Lin, T. H., Wu, T. C., Hung, K. C., Hsieh, Y. C., Mar, G. Y., Fang, C. Y., Chiu, K. M., Cheng, J. J. & Chen, J. H., 2012 Mar 1, In : Acta Cardiologica Sinica. 28, 1, p. 63-89 27 p.

Research output: Contribution to journalReview article

Cardiology
Taiwan
Guidelines
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Angiotensin Receptor Antagonists

Adult diabetic ketoacidosis and ketosis-prone type 2 diabetes mellitus

Tseng, J. Y., Hong, H. C., Ou, H-Y. & Wu, T. J., 2012 Aug, In : Journal of Internal Medicine of Taiwan. 23, 4, p. 274-281 8 p.

Research output: Contribution to journalReview article

Diabetic Ketoacidosis
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
Insulin
Autoantibodies
4 Citations (Scopus)

Afebrile mycotic aneurysm with rupture in right coronary artery after bare-metal stent implantation

Chen, I. C., Chao, T-H., Wu, I. H., Kan, C-D. & Fang, C. C., 2012 Dec, In : Acta Cardiologica Sinica. 28, 4, p. 344-348 5 p.

Research output: Contribution to journalReview article

Infected Aneurysm
Stents
Rupture
Coronary Vessels
Metals
Fluorodeoxyglucose F18
Positron-Emission Tomography
Thyroid Gland
Autoimmune Thyroiditis
Neoplasms
29 Citations (Scopus)

Complexity of β-lactamases among clinical Aeromonas isolates and its clinical implications

Chen, P-L., Ko, W-C. & Wu, C. J., 2012 Dec 1, In : Journal of Microbiology, Immunology and Infection. 45, 6, p. 398-403 6 p.

Research output: Contribution to journalReview article

Aeromonas
Lactams
Bacillus
Therapeutics
In Vitro Techniques
12 Citations (Scopus)

Epidemiology, disease spectrum and economic burden of non-typhoidal Salmonella infections in Taiwan, 2006-2008

Chen, P-L., Li, C-Y., Hsieh, T. H., Chang, C-M., Lee, H. C., Lee, N-Y., Wu, C. J., Lee, C. C., Shih, H-I. & Ko, W-C., 2012 Dec 1, In : Epidemiology and Infection. 140, 12, p. 2256-2263 8 p.

Research output: Contribution to journalReview article

Cost of Illness
Salmonella Infections
Taiwan
Salmonella
Epidemiology

Graves' ophthalmopathy

Kung, F. P., Hung, H-C., Ou, H-Y. & Wu, T. J., 2012 Feb 1, In : Journal of Internal Medicine of Taiwan. 23, 1, p. 9-20 12 p.

Research output: Contribution to journalReview article

Graves Ophthalmopathy
Glucocorticoids
Thyroid Gland
Graves Disease
Orbital Diseases
19 Citations (Scopus)

Online sex-seeking, substance use, and risky behaviors in taiwan: Results from the 2010 Asia internet MSM sex survey

Ko, N-Y., Koe, S., Lee, H. C., Yen, C. F., Ko, W-C. & Hsu, S. T., 2012 Oct 1, In : Archives of Sexual Behavior. 41, 5, p. 1273-1282 10 p.

Research output: Contribution to journalReview article

Taiwan
Internet
Odds Ratio
Sexual Partners
Street Drugs
7 Citations (Scopus)

Role of moxifloxacin for the treatment of commmunity-acquired complicated intra-abdominal infections in Taiwan

Lau, Y. J., Chen, Y. H., Huang, C. T., Lee, W. S., Liu, C. Y., Liu, J. W., Liu, H. D., Lee, Y. J., Chen, C. W., Ko, W-C. & Hsueh, P. R., 2012 Feb 1, In : Journal of Microbiology, Immunology and Infection. 45, 1, p. 1-6 6 p.

Research output: Contribution to journalReview article

Intraabdominal Infections
Taiwan
Fluoroquinolones
Enterobacteriaceae
Guidelines
18 Citations (Scopus)
Fluoroquinolones
Urinary Tract Infections
Levofloxacin
Sulfamethoxazole Drug Combination Trimethoprim
Microbial Sensitivity Tests