Department of Medical Laboratory Science and Biotechnology

Research Output 1987 2019

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Conference contribution
2019

An Aptamer Based Sandwich Assay for Simultaneous Detection of Multiple Cardiovascular Biomarkers on A Multilayered Integrated Microfluidic System

Sinha, A., Gopinathan, P., Chung, Y. D., Shiesh, S. C. & Lee, G. B., 2019 Jun, 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII. Institute of Electrical and Electronics Engineers Inc., p. 1075-1077 3 p. 8808551. (2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

biomarkers
Sandwich
Microfluidics
Biomarkers
Assays
2017
2 Citations (Scopus)

Microfluidic platform capable of performing automatic tissue slide-based selex and phage display for rapid screening of affinity reagents specific to ovarian cancer

Hung, L. Y., Fu, C. Y., Wang, C. H., Chuang, Y. J., Tsai, Y. C., Lo, Y. L., Lee, W. B., Shiesh, S-C., Chang, H. Y., Hsu, K-F. & Lee, G. B., 2017 Jul 26, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., p. 568-571 4 p. 7994112. (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bacteriophages
chutes
Microfluidics
reagents
affinity
2016
1 Citation (Scopus)

Integrated microfluidic systems for screening of aptamers specific to cardiovascular biomarkers

Sinha, A., Chung, Y. D., Gopinathan, P., Hung, L. Y., Yang, C. H., Shiesh, S-C. & Lee, G. B., 2016 Jan 1, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 67-68 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomarkers
Microfluidics
Antibodies
Screening
Ligands
2014
3 Citations (Scopus)

Measurement of glycated hemoglobin using an aptamer/antibody assay on an integrated microfluidic system

Chang, K. W., Li, J. L., Yang, C. H., Shiesh, S. C. & Lee, G. B., 2014 Sep 23, 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014. Institute of Electrical and Electronics Engineers Inc., p. 647-650 4 p. 6908895. (9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hemoglobin
Microfluidics
Antibodies
Assays
Medical problems

On-Chip HbA1C detection utlizing a compact surface pla-smon grating sensor integrated on a microfldic system

Chang, K. W., Chou, H. T., Yang, C. H., Shiesh, S. C., Lee, M. C. & Lee, G. B., 2014 Jan 1, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 2076-2078 3 p. (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Medical problems
Monitoring
Hemoglobin
Sensors
Surface plasmon resonance
1 Citation (Scopus)

Rapid and sensitive measurement of glycated hemoglobin for diabetes monitoring by using a two-aptamer assay on an integrated microfluidic system

Li, J., Chang, K. W., Yang, C. H., Shiesh, S-C. & Lee, G. B., 2014, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 1951-1953 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hemoglobin
Medical problems
Microfluidics
Assays
Monitoring
2013
1 Citation (Scopus)

An integrated microfluidic system for rapid HbA1c measurement

Wu, C. C., Chang, K. W., Lin, H. I., Shiesh, S-C. & Lee, G. B., 2013 Jan 1, 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. Chemical and Biological Microsystems Society, p. 684-686 3 p. (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Medical problems
Microfluidics
Monitoring
Hemoglobin
Glycosylated Hemoglobin A
2012
3 Citations (Scopus)

A rapid screening for hemoglobin-specific aptamers by using a continuous microfluidic system

Wu, C. C., Lin, H. I., Weng, C. H., Shiesh, S. C. & Lee, G. B., 2012 Jan 1, Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, p. 353-355 3 p. (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hemoglobin
Microfluidics
Screening
Hemoglobins
Ligands
1 Citation (Scopus)

Rapid measurement of AFP using AFP-specific aptamer on a microfluidic chip

Huang, C. J., Lin, H. I., Shiesh, S. C. & Lee, G. B., 2012 May 7, 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012. p. 874-877 4 p. 6170325. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

alpha-Fetoproteins
Microfluidics
beads
chips
suction
2011
1 Citation (Scopus)

An integrated microfluidic system for automating on-chip selex process to screen tumor cell-specific aptamers

Weng, C. H., Hung, L. Y., Lin, H. I., Hsieh, I. S., Shiesh, S. C., Chen, Y. L. & Lee, G. B., 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. Vol. 3. p. 2086-2088 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Tumors
Ligands
Cells
Microsystems

An integrated microfluidic system for rapid screening of alpha-fetoprotein aptamers

Huang, C. J., Lin, H. I., Shiesh, S-C. & Lee, G. B., 2011 Apr 13, 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011. p. 185-188 4 p. 5734392. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

alpha-Fetoproteins
Microfluidics
Screening
screening
Ligands
2010

A magnetic-bead based microfluidic system for automatic C-reactive protein detection

Lee, W. B., Lin, H. I., Shiesh, S-C. & Lee, G. B., 2010 Jul 12, Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. p. 257-260 4 p. (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
C-Reactive Protein
Proteins
Risk assessment
2 Citations (Scopus)

A microfluidic system integrated with optical detection devices for automatic detection of C-reactive protein

Lee, W. B., Chen, Y. H., Lin, H. I., Huang, C. J., Shiesh, S. C. & Lee, G. B., 2010 Jun 1, MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest. p. 979-982 4 p. 5442372. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
C-Reactive Protein
proteins
Proteins
chips
2009
4 Citations (Scopus)

A DEP chip with arc-shape microelectrode arrays for the separation of different-size particles

Chunag, C. H., Chen, Y. C., Hsu, Y. M., Huang, H-S., Hsiao, F. B. & Wang, C. H., 2009 Oct 12, 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009. p. 854-857 4 p. 5068709. (4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microelectrodes
Particle size
Electrodes
Microchannels
Electrophoresis
7 Citations (Scopus)

Impedance sensing of bladder cancer cells based on a single-cell-based DEP microchip

Chuang, C. H., Wei, C. H., Hsu, Y. M., Huang, H. S. & Hsiao, F. B., 2009 Dec 1, IEEE Sensors 2009 Conference - SENSORS 2009. p. 943-947 5 p. 5398183. (Proceedings of IEEE Sensors).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Electrophoresis
Cells
Microcavities
Electrodes
Time delay
1 Citation (Scopus)

Integrated microfluidic system for rapid selection of CRP aptamers utilizing systematic evolution of ligands by exponentail enrichment

Huang, C. J., Lin, H. I., Shiesh, S-C. & Lee, G. B., 2009 Jan 1, Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, p. 150-152 3 p. (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Ligands
Oligonucleotides
Microsystems
Biomolecules
2007

Molecular mimicry between SARS coronavirus spike protein and human protein

Hwa, K. Y., Lin, W. M., Hou, Y. I. & Yeh, T-M., 2007 Dec 1, Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007. p. 294-298 5 p. 4524122. (Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Proteins
Pathogens
Pulmonary diseases
Bioinformatics
Viruses
2006
2 Citations (Scopus)

3D microstructures array single-cell-based DEP chip for studying apoptosis of U937 & A431 cells

Chuang, C. H., Lee, Y-C., Huang, H-S., Hsiao, F. B., Hsu, Y. M., Wang, K. H., Ding, L. & Hsu, H. J., 2006 Dec 1, Proceedings of 1st IEEE International Conference on Nano Micro Engineered and Molecular Systems, 1st IEEE-NEMS. p. 1207-1210 4 p. 4135163. (Proceedings of 1st IEEE International Conference on Nano Micro Engineered and Molecular Systems, 1st IEEE-NEMS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Cell death
Electrophoresis
Apoptosis
Microstructure
Electrodes