Department of Medical Laboratory Science and Biotechnology

Research output

Research output per year 1987 2005 2006 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 876 Article
• 49 Review article
• 35 Conference contribution
• 27 Patent
• 30 More
  • 15 Comment/debate
  • 7 Letter
  • 5 Chapter
  • 2 Short survey
  • 1 Book

Research output per year

Research output per year

Search results

• 2019

  An Aptamer Based Sandwich Assay for Simultaneous Detection of Multiple Cardiovascular Biomarkers on A Multilayered Integrated Microfluidic System

  Sinha, A., Gopinathan, P., Chung, Y. D., Shiesh, S. C. & Lee, G. B., 2019 Jun, 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII. Institute of Electrical and Electronics Engineers Inc., p. 1075-1077 3 p. 8808551. (2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Microfluidics 100%
  • Cardiovascular Disease 95%
  • biomarkers 84%
  • Biomarkers 78%
  • Sandwich 76%
  6 Citations (Scopus)

• Improvement of Maturation State of Human Induced Pluripotent Stem Cell-Derived 3D Cardiac Microtissues by Defined Chemical Factors

  Huang, C-Y., Joca, R., Ong, C. S., Wilson, I., Teuben, R., Tomaselli, G. F. & Reich, D. H., 2019 Feb, 63 th BPS annual meeting. Baltimore

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2018

  A fibrinogen assay using specific aptamer on an integrated microfluidic chip

  Chung, Y. D., Sinha, A., Gopinathan, P., Lin, H. Y., Shiesh, S. C. & Lee, G. B., 2018 Jan 1, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 1882-1885 4 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 4).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Assays 100%
  • Microfluidics 90%
  • Antibodies 54%
  • Biomarkers 53%
  • Reagents 51%

• Effects of maturation factors on the mechanics and electrophysiology of 3D engineered cardiac microtissues

  Huang, C-Y., Ong, C. S., Wilson, I., Disilvestre, D., Tomaselli, G. F., Reich, D. H. & Joca, R., 2018 Mar, APS March Meeting 2018. Los Angeles, California. Maryland

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Integrated microfluidic platform for utilizing aptamer-based ELISA-like assay for simultaneous detection of multiple cardiovascular clinical samples

  Sinha, A., Gopinathan, P., Chung, Y. D., Shieh, S. C. & Lee, G. B., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 1181-1184 4 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 2).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Natriuretic Peptides 100%
  • Assays 81%
  • Microfluidics 74%
  • Antibodies 59%
  • Chemiluminescence 32%
• 2017

  Cardiac Remuscularization using 3D Bioprinted Cardiac Patches

  Ong, C. S., Fukunishi, T., Pitaktong, I., Samantha, H., Zhang, H., Huang, C-Y., Vricella, L., Tomaselli, G. F. & Hibino, N., 2017 Nov, American Heart Association's 2017 Scientific Sessions and Resuscitation Science Symposium, November 11–15, 2017. Anaheim, California

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Improvement of Mechanical Properties of Human Induced Pluripotent Stem Cell-Derived 3D Cardiac Microtissues by Defined Chemical Factors

  Huang, C-Y., Joca, R., Ong, C. S., Nashed, A., Disilvestre, D., Tomaselli, G. F. & Reich, D. H., 2017 Nov, American Heart Association's 2017 Scientific Sessions and Resuscitation Science Symposium, November 11–15, 2017. Anaheim, California

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Microfluidic platform capable of performing automatic tissue slide-based selex and phage display for rapid screening of affinity reagents specific to ovarian cancer

  Hung, L. Y., Fu, C. Y., Wang, C. H., Chuang, Y. J., Tsai, Y. C., Lo, Y. L., Lee, W. B., Shiesh, S. C., Chang, H. Y., Hsu, K. F. & Lee, G. B., 2017 Jul 26, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., p. 568-571 4 p. 7994112. (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Phage display 100%
  • Reagents 62%
  • reagents 59%
  • affinity 57%
  • Microfluidics 55%
  2 Citations (Scopus)
• 2016

  Integrated microfluidic systems for screening of aptamers specific to cardiovascular biomarkers

  Sinha, A., Chung, Y. D., Gopinathan, P., Hung, L. Y., Yang, C. H., Shiesh, S. C. & Lee, G. B., 2016, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 67-68 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Antibodies 95%
  • Biomarkers 93%
  • Natriuretic Peptides 80%
  • Microfluidics 79%
  • Screening 70%
  3 Citations (Scopus)

• New Approach for Quantitative Single-Cell Analysis of Magnetic Labelling Efficacy

  Huang, C-Y., Jing-Ci, S., Te-Ho, W., Peng, Y. H. & Wei, Z. H., 2016 Aug, 2016 International Conference of Asian Union of Magnetics Societies. Tainan , Taiwan

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2015

  Rotating magnetic field induced mechanical stress and cell death on magnetically labeled cell

  Huang, C-Y. & Wei, Z. H., 2015 May, 2015 IEEE International Magnetics Conference. Beijing, China

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2014

  Cell culture array using micron ferromagnetic ring-shaped thin films

  Huang, C-Y., Ger, T. R., Wei, Z. H. & Lai, M. F., 2014 Nov, 59th Conference on Magnetism and Magnetic Materials. Honolulu, Hawaii

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Linear Cell Patterning using Concentric Magnetic Structure

  Huang, C-Y., Ger, T. R., Wei, Z. H. & Lai, M. F., 2014 Nov, 6th International Symposium on Microchemistry and Microsystems. Singapore

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Magnetic cantilever actuator with magnetic thin films structures

  Huang, C-Y., Ger, T. R., Huang, H. T. & Wei, Z. H., 2014 Nov, 59th Conference on Magnetism and Magnetic Materials. Honolulu, Hawaii

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Measurement of glycated hemoglobin using an aptamer/antibody assay on an integrated microfluidic system

  Chang, K. W., Li, J. L., Yang, C. H., Shiesh, S. C. & Lee, G. B., 2014 Sept 23, 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014. Institute of Electrical and Electronics Engineers Inc., p. 647-650 4 p. 6908895. (9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Hemoglobin 100%
  • Antibodies 90%
  • Assays 82%
  • Microfluidics 75%
  • Medical problems 31%
  6 Citations (Scopus)

• Nanotoxicity of carcinoma cells with different amounts of endocytic magnetic nanoparticles

  Huang, C-Y., Ger, T. R., Fu, P. W., Hu, K. H., Peng, Y. H. & Lai, M. F., 2014 Jul, 10th European Conference on Magnetic Sensors and Actuators. Vienna, Austria

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• On-Chip HbA_1C detection utlizing a compact surface pla-smon grating sensor integrated on a microfldic system

  Chang, K. W., Chou, H. T., Yang, C. H., Shiesh, S. C., Lee, M. C. & Lee, G. B., 2014 Jan 1, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 2076-2078 3 p. (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Medical problems 100%
  • Surface plasmon resonance 71%
  • Hemoglobin 64%
  • Monitoring 50%
  • Microfluidics 48%

• On-Chip HbA_1C detection utlizing a compact surface pla-smon grating sensor integrated on a microfldic system

  Chang, K. W., Chou, H. T., Yang, C. H., Shiesh, S. C., Lee, M. C. & Lee, G. B., 2014 Jan 1, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 2076-2078 3 p. (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Medical problems 100%
  • Surface plasmon resonance 71%
  • Hemoglobin 64%
  • Monitoring 50%
  • Microfluidics 48%

• Rapid and sensitive measurement of glycated hemoglobin for diabetes monitoring by using a two-aptamer assay on an integrated microfluidic system

  Li, J., Chang, K. W., Yang, C. H., Shiesh, S-C. & Lee, G. B., 2014, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 1951-1953 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Hemoglobin 100%
  • Assays 82%
  • Medical problems 78%
  • Microfluidics 75%
  • Nucleic acids 51%
  3 Citations (Scopus)

• The measurement of magnetic force of micro/nano thin film by inclined surface

  Huang, C-Y., Yang, K. C. & Wei, Z. H., 2014 Oct, 3rd International conference of Asian Union of Magnetics Societies. Haikou, China

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2013

  An integrated microfluidic system for rapid HbA1c measurement

  Wu, C. C., Chang, K. W., Lin, H. I., Shiesh, S-C. & Lee, G. B., 2013 Jan 1, 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013. Chemical and Biological Microsystems Society, p. 684-686 3 p. (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; vol. 1).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Medical problems 100%
  • Microfluidics 96%
  • Hemoglobin 42%
  • Biomarkers 37%
  • Assays 35%
  1 Citation (Scopus)

• Comparative analysis of endocytic capacities to superparamagnetic iron oxide nanoparticles between different carcinoma cells via magnetophoresis

  Huang, C-Y., Ger, T. R., Lai, M. F., Hu, K. H., Peng, Y. H. & Fu, P. W., 2013 Nov, 58th Conference on Magnetism and Magnetic Materials. Denver, Colorado

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Cytotoxicity effects of cervical cancer cells mediated by intracellular magnetic hyperthermia

  Huang, C-Y., Hu, K. H., Ger, T. R., Fu, P. W., Peng, Y. H. & Lai, M. F., 2013 Jul, 2013 International Symposium on Advanced Magnetic Materials and Applications. Taichung, Taiwan

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Simple strategy for magnetic labeling of living cells with magnetic nanoparticles and collagen

  Huang, C-Y., Ger, T. R. & Lai, M. F., 2013 Jan, The 12th Joint MMM/Intermag Conference. Chicago, USA

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2012

  A rapid screening for hemoglobin-specific aptamers by using a continuous microfluidic system

  Wu, C. C., Lin, H. I., Weng, C. H., Shiesh, S. C. & Lee, G. B., 2012 Jan 1, Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, p. 353-355 3 p. (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Hemoglobin 100%
  • Microfluidics 75%
  • Screening 65%
  • Oligonucleotides 52%
  • Biomarkers 44%
  3 Citations (Scopus)

• Rapid measurement of AFP using AFP-specific aptamer on a microfluidic chip

  Huang, C. J., Lin, H. I., Shiesh, S. C. & Lee, G. B., 2012, 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012. p. 874-877 4 p. 6170325. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Microfluidics 100%
  • beads 94%
  • chips 74%
  • suction 52%
  • modules 38%
  1 Citation (Scopus)
• 2011

  An integrated microfluidic system for automating on-chip selex process to screen tumor cell-specific aptamers

  Weng, C. H., Hung, L. Y., Lin, H. I., Hsieh, I. S., Shiesh, S. C., Chen, Y. L. & Lee, G. B., 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. Vol. 3. p. 2086-2088 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Microfluidics 79%
  • Tumors 77%
  • Cells 73%
  • Nucleic acids 36%
  • Microsystems 30%
  1 Citation (Scopus)

• An integrated microfluidic system for rapid screening of alpha-fetoprotein aptamers

  Huang, C. J., Lin, H. I., Shiesh, S-C. & Lee, G. B., 2011 Apr 13, 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011. p. 185-188 4 p. 5734392. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Microfluidics 79%
  • ligands 75%
  • Screening 70%
  • screening 65%
  • Amplification 38%
• 2010

  A magnetic-bead based microfluidic system for automatic C-reactive protein detection

  Lee, W. B., Lin, H. I., Shiesh, S-C. & Lee, G. B., 2010 Jul 12, Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. p. 257-260 4 p. (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009; vol. 1).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Microfluidics 100%
  • Proteins 86%
  • Protein 39%
  • Risk Assessment 28%
  • Risk assessment 23%
  1 Citation (Scopus)

• A microfluidic system integrated with optical detection devices for automatic detection of C-reactive protein

  Lee, W. B., Chen, Y. H., Lin, H. I., Huang, C. J., Shiesh, S. C. & Lee, G. B., 2010 Jun 1, MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest. p. 979-982 4 p. 5442372. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Microfluidics 100%
  • Proteins 86%
  • proteins 75%
  • Protein 39%
  • chips 21%
  2 Citations (Scopus)
• 2009

  A DEP chip with arc-shape microelectrode arrays for the separation of different-size particles

  Chunag, C. H., Chen, Y. C., Hsu, Y. M., Huang, H-S., Hsiao, F. B. & Wang, C. H., 2009 Oct 12, 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009. p. 854-857 4 p. 5068709. (4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Microelectrodes 100%
  • Particle size 70%
  • Electrodes 57%
  • Microchannels 32%
  • Electrophoresis 9%
  4 Citations (Scopus)

• Impedance sensing of bladder cancer cells based on a single-cell-based DEP microchip

  Chuang, C. H., Wei, C. H., Hsu, Y. M., Huang, H. S. & Hsiao, F. B., 2009 Dec 1, IEEE Sensors 2009 Conference - SENSORS 2009. p. 943-947 5 p. 5398183. (Proceedings of IEEE Sensors).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Electrophoresis 100%
  • Cells 74%
  • Acoustic impedance 56%
  • Microcavities 30%
  • Electrodes 22%
  8 Citations (Scopus)

• Integrated microfluidic system for rapid selection of CRP aptamers utilizing systematic evolution of ligands by exponentail enrichment

  Huang, C. J., Lin, H. I., Shiesh, S. C. & Lee, G. B., 2009, Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, p. 150-152 3 p. (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Microfluidics 79%
  • Oligonucleotides 56%
  • Oligomers 54%
  • Biomolecules 53%
  • Biomarkers 46%
  1 Citation (Scopus)
• 2007

  Molecular mimicry between SARS coronavirus spike protein and human protein

  Hwa, K. Y., Lin, W. M., Hou, Y. I. & Yeh, T. M., 2007, Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007. p. 294-298 5 p. 4524122. (Proceedings of the Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Proteins 100%
  • Pathogens 73%
  • Pulmonary diseases 37%
  • Peptides 35%
  • Viruses 32%
  4 Citations (Scopus)
• 2006

  3D microstructures array single-cell-based DEP chip for studying apoptosis of U937 & A431 cells

  Chuang, C. H., Lee, Y. C., Huang, H. S., Hsiao, F. B., Hsu, Y. M., Wang, K. H., Ding, L. & Hsu, H. J., 2006, Proceedings of 1st IEEE International Conference on Nano Micro Engineered and Molecular Systems, 1st IEEE-NEMS. p. 1207-1210 4 p. 4135163. (Proceedings of 1st IEEE International Conference on Nano Micro Engineered and Molecular Systems, 1st IEEE-NEMS).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Cell death 100%
  • Dielectrophoresis 89%
  • Electrophoresis 87%
  • U937 Cells 85%
  • Electrodes 51%
  3 Citations (Scopus)