Department of Microbiology and Immunology

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2011

Galectin-1 binds to influenza virus and ameliorates influenza virus pathogenesis

Yang, M. L., Chen, Y. H., Wang, S. W., Huang, Y. J., Leu, C. H., Yeh, N. C., Chu, C. Y., Lin, C. C., Shieh, G. S., Chen, Y. L., Wang, J. R., Wang, C. H., Wu, C. L. & Shiau, A. L., 2011 Oct 1, In : Journal of Virology. 85, 19, p. 10010-10020 11 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr-Abl inhibitor and cooperatively induces glycogen synthase kinase-3-regulated apoptosis

Huang, W. C., Tsai, C. C., Chen, C. L., Chen, T. Y., Chen, Y. P., Lin, Y. S., Lu, P. J., Lin, C. M., Wang, S. H., Tsao, C. W., Wang, C. Y., Cheng, Y. L., Hsieh, C. Y., Tseng, P. C. & Lin, C. F., 2011 Oct 1, In : FASEB Journal. 25, 10, p. 3661-3673 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Glycogen synthase kinase-3 facilitates con a-induced IFN-γ-mediated immune hepatic injury

Tsai, C. C., Huang, W. C., Chen, C. L., Hsieh, C. Y., Lin, Y. S., Chen, S. H., Yang, K. C. & Lin, C. F., 2011 Oct 1, In : Journal of Immunology. 187, 7, p. 3867-3877 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Immunostimulatory and antigen delivery properties of liposomes made up of total polar lipids from non-pathogenic bacteria leads to efficient induction of both innate and adaptive immune responses

Faisal, S. M., Chen, J. W., McDonough, S. P., Chang, C. F., Teng, C. H. & Chang, Y. F., 2011 Mar 16, In : Vaccine. 29, 13, p. 2381-2391 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli

Cheng, Y. L., Huang, W. C., Chen, C. L., Tsai, C. C., Wang, C. Y., Chiu, W. H., Chen, Y. L., Lin, Y. S., Chang, C. F. & Lin, C. F., 2011 Aug 26, In : Biochemical and Biophysical Research Communications. 412, 2, p. 334-340 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Inhibition of cartilage damage by pro-opiomelanocortin prohormone overexpression in a rat model of osteoarthritis

Shen, P. C., Shiau, A-L., Jou, I. M., Lee, C. H., Tai, M. H., Juan, H. Y., Lin, P. R., Liu, G. S., Wu, C-L. & Hsieh, J. L., 2011 Mar 1, In : Experimental Biology and Medicine. 236, 3, p. 334-340 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Inhibition of neutrophil apoptosis via sphingolipid signaling in acute lung injury

Lin, W. C., Lin, C. F., Chen, C. L., Chen, C. W. & Lin, Y. S., 2011 Oct 1, In : Journal of Pharmacology and Experimental Therapeutics. 339, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Kinase Gene Expression and Subcellular Protein Expression Pattern of Protein Kinase C Isoforms in Curcumin-treated Human Hepatocellular Carcinoma Hep 3B Cells

Kao, H. H., Wu, C. J., Won, S. J., Shin, J. W., Liu, H. S. & Su, C. L., 2011 Jun 1, In : Plant Foods for Human Nutrition. 66, 2, p. 136-142 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Macrophage migration inhibitory factor induced by dengue virus infection increases vascular permeability

Chuang, Y. C., Lei, H. Y., Liu, H. S., Lin, Y. S., Fu, T. F. & Yeh, T. M., 2011 May 1, In : Cytokine. 54, 2, p. 222-231 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Methylation of the CpG sites only on the sense strand of the APC gene is specific for hepatocellular carcinoma

Jain, S., Chang, T. T., Hamilton, J. P., Lin, S. Y., Lin, Y. J., Evans, A. A., Selaru, F. M., Lin, P. W., Chen, S. H., Block, T. M., Hu, C. T., Song, W., Meltzer, S. J. & Su, Y. H., 2011 Nov 2, In : PloS one. 6, 11, e26799.

Research output: Contribution to journalArticle

25 Citations (Scopus)
18 Citations (Scopus)
28 Citations (Scopus)

Prothymosin alpha interacts with C-terminal domain of histone H1 and dissociates p53-histone H1 complex

Zakharova, N. I., Sokolov, V. V., Suvorova, A. A., Shiau, A. L., Wu, C. L. & Evstafieva, A. G., 2011 Aug 1, In : Molecular Biology. 45, 4, p. 624-633 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation

Wu, S. Y., Lan, S. H., Cheng, D. E., Chen, W. K., Shen, C. H., Lee, Y. R., Zuchini, R. & Liu, H. S., 2011 Dec, In : Neoplasia. 13, 12, p. 1171-1182 12 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Structural differences between the Streptococcus agalactiae housekeeping and pilus-specific sortases: SrtA and SrtC1

Khare, B., Krishnan, V., Rajashankar, K. R., I-Hsiu, H., Xin, M., Ton-That, H. & Narayana, S. V., 2011 Sep 6, In : PloS one. 6, 8, e22995.

Research output: Contribution to journalArticle

22 Citations (Scopus)

TBK1-associated Protein in Endolysosomes (TAPE) is an innate immune regulator modulating the TLR3 and TLR4 signaling pathways

Chang, C. H., Lai, L. C., Cheng, H. C., Chen, K. R., Syue, Y. Z., Lu, H. C., Lin, W. Y., Chen, S. H., Huang, H. S., Shiau, A. L., Lei, H. Y., Qin, J. & Ling, P., 2011 Mar 4, In : Journal of Biological Chemistry. 286, 9, p. 7043-7051 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

T cell augments the antitumor activity of tumor-targeting Salmonella

Lee, C. H., Hsieh, J. L., Wu, C. L., Hsu, P. Y. & Shiau, A. L., 2011 May 1, In : Applied Microbiology and Biotechnology. 90, 4, p. 1381-1388 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

The crystal structure analysis of group B streptococcus sortase C1: A model for the "lid" movement upon substrate binding

Khare, B., Fu, Z. Q., Huang, I. H., Hung, T. T. & Narayana, S. V. L., 2011 Dec 9, In : Journal of Molecular Biology. 414, 4, p. 563-577 15 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

The deficient cleavage of M protein-bound IgG by IdeS: Insight into the escape of Streptococcus pyogenes from antibody-mediated immunity

Su, Y. F., Chuang, W. J., Wang, S. M., Chen, W. Y., Chiang-Ni, C., Lin, Y. S., Wu, J. J. & Liu, C. C., 2011 Oct 1, In : Molecular Immunology. 49, 1-2, p. 134-142 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
22 Citations (Scopus)

T helper cells promote disease progression of osteoarthritis by inducing macrophage inflammatory protein-1γ

Shen, P. C., Wu, C. L., Jou, I. M., Lee, C. H., Juan, H. Y., Lee, P. J., Chen, S. H. & Hsieh, J. L., 2011 Jun 1, In : Osteoarthritis and Cartilage. 19, 6, p. 728-736 9 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

The potential role of interferon-regulatory factor 7 among Taiwanese patients with systemic lupus erythematosus

Lin, L. H., Ling, P. & Liu, M. F., 2011 Sep 1, In : Journal of Rheumatology. 38, 9, p. 1914-1919 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer

Yeh, C. Y., Shin, S. M., Yeh, H. H., Wu, T. J., Shin, J. W., Chang, T. Y., Raghavaraju, G., Lee, C. T., Chiang, J. H., Tseng, V. S., Lee, Y. C. G., Shen, C. H., Chow, N. H. & Liu, H. S., 2011 Apr 16, In : BMC cancer. 11, 139.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2012

Acquisition of an enhanced aggressive phenotype in human lung cancer cells selected by suboptimal doses of cisplatin following cell deattachment and reattachment

Hsieh, J. L., Lu, C. S., Huang, C. L., Shieh, G. S., Su, B. H., Su, Y. C., Lee, C. H., Chang, M. Y., Wu, C. L. & Shiau, A. L., 2012 Aug 1, In : Cancer Letters. 321, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

Li, Y. T., Chen, S. Y., Wang, C. R., Liu, M. F., Lin, C. C., Jou, I. M., Shiau, A. L. & Wu, C. L., 2012 Oct 1, In : Arthritis and Rheumatism. 64, 10, p. 3240-3245 6 p.

Research output: Contribution to journalArticle

82 Citations (Scopus)
30 Citations (Scopus)

Annexin A2 silencing induces G2 arrest of non-small cell lung cancer cells through p53-dependent and -independent mechanisms

Wang, C. Y., Chen, C. L., Tseng, Y. L., Fang, Y. T., Lin, Y. S., Su, W. C., Chen, C. C., Chang, K. C., Wang, Y. C. & Lin, C. F., 2012 Sep 21, In : Journal of Biological Chemistry. 287, 39, p. 32512-32524 13 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Catenarin prevents type 1 diabetes in nonobese diabetic mice via inhibition of leukocyte migration involving the MEK6/p38 and MEK7/JNK pathways

Shen, M. Y., Lin, Y. P., Yang, B. C., Jang, Y. S., Chiang, C. K., Mettling, C., Chen, Z. W., Sheu, J. R., Chang, C. L., Lin, Y. L. & Yang, W. C., 2012 Mar 19, In : Evidence-based Complementary and Alternative Medicine. 2012, 982396.

Research output: Contribution to journalArticle

8 Citations (Scopus)

CCAAT/enhancer binding protein delta (CEBPD) elevating PTX3 expression inhibits macrophage-mediated phagocytosis of dying neuron cells

Ko, C. Y., Chang, L. H., Lee, Y. C., Sterneck, E., Cheng, C. P., Chen, S., Huang, A. M., Tseng, T-C. & Wang, J-M., 2012 Jan 1, In : Neurobiology of Aging. 33, 2, p. 422.e11-422.e25

Research output: Contribution to journalArticle

36 Citations (Scopus)

CD4 T-cell-independent antibody response reduces enterovirus 71 lethality in mice by decreasing tissue viral loads

Wang, L. C., Kao, C. M., Ling, P., Su, I. J., Chang, T. M. & Chen, S. H., 2012 Dec 3, In : Clinical and Developmental Immunology. 2012, 580696.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cell surface sialylation affects binding of enterovirus 71 to rhabdomyosarcoma and neuroblastoma cells

Su, P. Y., Liu, Y. T., Chang, H. Y., Huang, S. W., Wang, Y. F., Yu, C. K., Wang, J. R. & Chang, C. F., 2012 Aug 3, In : BMC microbiology. 12, 162.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Crystal structure of a human single domain antibody dimer formed through V H-V H non-covalent interactions

Baral, T. N., Chao, S. Y., Li, S., Tanha, J., Arbabi-Ghahroudi, M., Zhang, J. & Wang, S., 2012 Jan 12, In : PloS one. 7, 1, e30149.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Dengue virus nonstructural protein NS1 binds to prothrombin/thrombin and inhibits prothrombin activation

Lin, S. W., Chuang, Y. C., Lin, Y. S., Lei, H. Y., Liu, H. S. & Yeh, T. M., 2012 Mar 1, In : Journal of Infection. 64, 3, p. 325-334 10 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Endothelial cell surface expression of protein disulfide isomerase activates β1 and β3 integrins and facilitates dengue virus infection

Wan, S. W., Lin, C. F., Lu, Y. T., Lei, H. Y., Anderson, R. & Lin, Y. S., 2012 May 1, In : Journal of Cellular Biochemistry. 113, 5, p. 1681-1691 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Enterovirus 71 blocks selectively type I interferon production through the 3C viral protein in mice

Lee, Y. P., Wang, Y. F., Wang, J. R., Huang, S. W. & Yu, C. K., 2012 Nov 1, In : Journal of Medical Virology. 84, 11, p. 1779-1789 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Environmental pH changes, but not the LuxS signalling pathway, regulate SpeB expression in M1 group A streptococci

Chiang-Ni, C., Zheng, P. X., Tsai, P. J., Chuang, W. J., Lin, Y. S., Liu, C. C. & Wu, J. J., 2012 Jan 1, In : Journal of Medical Microbiology. 61, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Factors affecting herpes simplex virus reactivation from the explanted mouse brain

Yao, H. W., Ling, P., Chen, S. H., Tung, Y. Y. & Chen, S. H., 2012 Nov 10, In : Virology. 433, 1, p. 116-123 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Fas ligand enhances malignant behavior of tumor cells through interaction with met, hepatocyte growth factor receptor, in lipid rafts

Lin, H. C., Lai, P. Y., Lin, Y. P., Huang, J. Y. & Yang, B. C., 2012 Jun 8, In : Journal of Biological Chemistry. 287, 24, p. 20664-20673 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Hypoxia imaging predicts success of hypoxia-induced cytosine deaminase/5-fluorocytosine gene therapy in a murine lung tumor model

Lee, B. F., Lee, C. H., Chiu, N. T., Hsia, C. C., Shen, L. H. & Shiau, A. L., 2012 Apr 1, In : Cancer Gene Therapy. 19, 4, p. 255-262 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Identification of colorectal cancer recurrence-related microRNAs

Ju, J. A., Huang, Y. C., Lan, S. H., Wang, T. H., Lin, P-C., Lee, J. C., Niu, K. C., Tian, Y. F. & Liu, H-S., 2012 Mar 1, In : Genomic Medicine, Biomarkers, and Health Sciences. 4, 1-2, p. 19-20 2 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Immune response and protective efficacy of live attenuated Salmonella vaccine expressing antigens of Mycobacterium avium subsp. paratuberculosis against challenge in mice

Chandra, S., Faisal, S. M., Chen, J. W., Chen, T. T., McDonough, S. P., Liu, S., Moreira, M. A. S., Akey, B. L., Chang, C. F. & Chang, Y. F., 2012 Dec 17, In : Vaccine. 31, 1, p. 242-251 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Immunogenicity and protective efficacy of the Mycobacterium avium subsp. paratuberculosis attenuated mutants against challenge in a mouse model

Chen, J. W., Faisal, S. M., Chandra, S., McDonough, S. P., Moreira, M. A. S., Scaria, J., Chang, C. F., Bannantine, J. P., Akey, B. & Chang, Y. F., 2012 Apr 19, In : Vaccine. 30, 19, p. 3015-3025 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma

Jain, S., Chen, S., Chang, K. C., Lin, Y. J., Hu, C. T., Boldbaatar, B., Hamilton, J. P., Lin, S. Y., Chang, T. T., Chen, S. H., Song, W., Meltzer, S. J., Block, T. M. & Su, Y. H., 2012 Apr 20, In : PloS one. 7, 4, e35789.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Inhibiting glycogen synthase kinase-3 decreases 12-O-tetradecanoylphorbol- 13-acetate-induced interferon-γ-mediated skin inflammation

Hsieh, C. Y., Chen, C. L., Tsai, C. C., Huang, W. C., Tseng, P. C., Lin, Y. S., Chen, S. H., Wong, T. W., Choi, P. C. & Lin, C. F., 2012 Oct 1, In : Journal of Pharmacology and Experimental Therapeutics. 343, 1, p. 125-133 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Interferon-γ stimulates p11-dependent surface expression of annexin A2 in lung epithelial cells to enhance phagocytosis

Fang, Y. T., Lin, C. F., Wang, C. Y., Anderson, R. & Lin, Y-S., 2012 Jun 1, In : Journal of Cellular Physiology. 227, 6, p. 2775-2787 13 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation

Chuang, Y. C., Su, W. H., Lei, H. Y., Lin, Y. S., Liu, H. S., Chang, C. P. & Yeh, T. M., 2012 May 22, In : PloS one. 7, 5, e37613.

Research output: Contribution to journalArticle

43 Citations (Scopus)

MicroRNA-21-mediated regulation of Sprouty2 protein expression enhances the cytotoxic effect of 5-fluorouracil and metformin in colon cancer cells

Feng, Y. H., Wu, C. L., Shiau, A. L., Lee, J. C., Chang, J. G., Lu, P. J., Tung, C. L., Feng, L. Y., Huang, W. T. & Tsao, C. J., 2012 May 1, In : International journal of molecular medicine. 29, 5, p. 920-926 7 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Multivalent structure of galectin-1-nanogold complex serves as potential therapeutics for rheumatoid arthritis by enhancing receptor clustering

Huang, Y. J., Shiau, A. L., Chen, S. Y., Chen, Y. L., Wang, C. R., Tsai, C. Y., Chang, M. Y., Li, Y. T., Leu, C. H. & Wu, C. L., 2012 Jan, In : European Cells and Materials. 23, p. 170-181 12 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Mutations in VP2 and VP1 capsid proteins increase infectivity and mouse lethality of enterovirus 71 by virus binding and RNA accumulation enhancement

Huang, S. W., Wang, Y. F., Yu, C. K., Su, I. J. & Wang, J. R., 2012 Jan 5, In : Virology. 422, 1, p. 132-143 12 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)