Department of Microbiology and Immunology

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[Prothymosin alpha interacts with C-terminal domain of histone H1 and dissociates p53-histone H1 complex].

Zakharova, N. I., Sokolov, V. V., Suvorova, A. A., Shiau, A. I., Wu, C. L. & Efstaf'eva, A. G., 2011 Jul 1, In : Molekuliarnaia biologiia. 45, 4, p. 679-688 10 p.

Research output: Contribution to journalArticle

6-Hydroxydopamine induces thymocyte apoptosis in mice

Tsao, C. W., Cheng, J. T., Shen, C. L. & Lin, Y. S., 1996 Apr, In : Journal of Neuroimmunology. 65, 2, p. 91-95 5 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Aberrant integrin activation induces p38 MAPK phosphorylation resulting in suppressed Fas-mediated apoptosis in T cells: Implications for rheumatoid arthritis

Lin, Y. P., Su, C. C., Huang, J. Y., Lin, H. C., Cheng, Y. J., Liu, M. F. & Yang, B. C., 2009 Oct 1, In : Molecular Immunology. 46, 16, p. 3328-3335 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Aberrant Prothymosin-alpha Expression in Human Bladder Cancer

Tsai, Y-S., Jou, Y. C., Lee, G. F., Chen, Y. C., Shiau, A-L., Tsai, H. T., Wu, C-L. & Tzai, T. S., 2009 Jan 1, In : Urology. 73, 1, p. 188-192 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

A biological strategy for fabrication of Au/EGFP nanoparticle conjugates retaining bioactivity

Tsai, C. Y., Shiau, A-L., Cheng, P. C., Shieh, D-B., Chen, D-H., Chou, C-H., Yeh, C-S. & Wu, C-L., 2004 Jul 1, In : Nano letters. 4, 7, p. 1209-1212 4 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abrogation of streptococcal pyrogenic exotoxin B-mediated suppression of phagocytosis in U937 cells by Cordyceps sinensis mycelium via production of cytokines

Kuo, C. F., Chen, C. C., Lin, C. F., Jan, M. S., Huang, R. Y., Luo, Y. H., Chuang, W. J., Sheu, C. C. & Lin, Y. S., 2007 Feb 1, In : Food and Chemical Toxicology. 45, 2, p. 278-285 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Absence of CXCL10 aggravates herpes stromal keratitis with reduced primary neutrophil influx in mice

Shen, F. H., Wang, S. W., Yeh, T. M., Tung, Y. Y., Hsu, S. M. & Chen, S. H., 2013 Jul 30, In : Journal of Virology. 87, 15, p. 8502-8510 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Acceleration time in normal fetal umbilical artery at term and its relationship to the cord blood hematocrit

Chang, FM. M., Yao, BL. L., Yu, CH. H., Huang, SC. C., Lin, YS. S. & Ko, HC. C., 1995 Jan, In : Journal of Clinical Ultrasound. 23, 1, p. 33-37 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Accumulation of viral transcripts and DNA during establishment of latency by herpes simplex virus

Kramer, M. F., Chen, S. H., Knipe, D. M. & Coen, D. M., 1998 Feb 1, In : Journal of Virology. 72, 2, p. 1177-1185 9 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

A cellular ELISA to screen lectin-like compounds for cancer cell binding

Chang, C-P., Cheng, W. C. & Lei, H. Y., 2005 May 1, In : Letters in Drug Design and Discovery. 2, 3, p. 182-188 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

A computerized management system for cell bank

Wu, C. L., Wu, P. & Shiau, A. L., 1999 Nov 15, In : Analytical Biochemistry. 275, 2, p. 260-262 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Acquisition of an enhanced aggressive phenotype in human lung cancer cells selected by suboptimal doses of cisplatin following cell deattachment and reattachment

Hsieh, J. L., Lu, C. S., Huang, C. L., Shieh, G. S., Su, B. H., Su, Y. C., Lee, C. H., Chang, M. Y., Wu, C. L. & Shiau, A. L., 2012 Aug 1, In : Cancer Letters. 321, 1, p. 36-44 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Activation of coagulation and fibrinolysis during dengue virus infection

Huang, Y. H., Liu, C-C., Wang, S-T., Lei, H. Y., Liu, H-S., Lin, Y-S., Wu, H-L. & Yeh, T-M., 2001 Feb 14, In : Journal of Medical Virology. 63, 3, p. 247-251 5 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)
36 Citations (Scopus)

Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes

Cheng, Y. L., Lin, Y. S., Chen, C. L., Tsai, T. T., Tsai, C. C., Wu, Y. W., Ou, Y. D., Chu, Y. Y., Wang, J. M., Yu, C. Y. & Lin, C. F., 2016 Aug 26, In : Scientific reports. 6, 32000.

Research output: Contribution to journalArticle

19 Citations (Scopus)
96 Citations (Scopus)

Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection

Hsieh, J. L., Shen, P. C., Shiau, A-L., Jou, I. M., Lee, C. H., Teo, M. L., Wang, C-R., Chao, J., Chao, L. & Wu, C-L., 2009 Feb 1, In : Human Gene Therapy. 20, 2, p. 147-158 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Adenovirus-mediated prothymosin α gene transfer inhibits the development of atherosclerosis in apoe-deficient mice

Chang, M. Y., Yang, Y. S., Tsai, M. L., Lee, C. H., Chang, C. J., Shiau, A. L. & Wu, C. L., 2014 Mar 15, In : International Journal of Biological Sciences. 10, 4, p. 358-366 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Adipose-Derived Stem Cells Protect Skin Flaps against Ischemia/Reperfusion Injury via IL-6 Expression

Pu, C. M., Liu, C. W., Liang, C. J., Yen, Y. H., Chen, S. H., Jiang-Shieh, Y. F., Chien, C. L., Chen, Y. C. & Chen, Y. L., 2017 Jun, In : Journal of Investigative Dermatology. 137, 6, p. 1353-1362 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

A glycine-to-arginine substitution in the triple-helical domain of type VII collagen in a family with dominant dystrophic epidermolysis bullosa pruriginosa

Lee, J. Y. Y., Pulkkinen, L., Liu, H. S., Chen, Y. F. & Uitto, J., 1997 Jan 1, In : Journal of Investigative Dermatology. 108, 6, p. 947-949 3 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Allelic loss of 14q32 in the pathogenesis of gastrointestinal and ampullary malignancies: Mapping of the target region to a 17 cM interval

Dai, Y. C., Ho, C. L., Tsai, Y. C., Hsu, Y. H., Chang, Y. C., Liu, H. S., Chen, H. H. W. & Chow, N. H., 2005 Feb 1, In : Journal of Cancer Research and Clinical Oncology. 131, 2, p. 94-100 7 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
57 Citations (Scopus)
2 Citations (Scopus)

A locked nucleic acid clamp-mediated PCR assay for detection of a p53 codon 249 hotspot mutation in urine

Lin, S. Y., Dhillon, V., Jain, S., Chang, T. T., Hu, C. T., Lin, Y. J., Chen, S. H., Chang, K. C., Song, W., Yu, L., Block, T. M. & Su, Y. H., 2011 Sep, In : Journal of Molecular Diagnostics. 13, 5, p. 474-484 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
19 Citations (Scopus)

Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

Li, Y. T., Chen, S. Y., Wang, C. R., Liu, M. F., Lin, C. C., Jou, I. M., Shiau, A. L. & Wu, C. L., 2012 Oct 1, In : Arthritis and Rheumatism. 64, 10, p. 3240-3245 6 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Amelioration of collagen-induced arthritis in rats by adenovirus-mediated PTEN gene transfer

Wang, C-R., Shiau, A-L., Chen, S. Y., Lin, L. L., Tai, M. H., Shieh, G. S., Lin, P. R., Yo, Y. T., Lee, C. H., Kuo, S. M., Liu, M-F., Jou, I. M., Yang, C-Y., Shen, P. C., Lee, H. L. & Wu, C-L., 2008 Jun 1, In : Arthritis and Rheumatism. 58, 6, p. 1650-1656 7 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Amelioration of collagen-induced arthritis in rats by Nanogold

Tsai, C. Y., Shiau, A-L., Chen, S. Y., Chen, Y-H., Cheng, P. C., Chang, M. Y., Chen, D-H., Chou, C-H., Wang, C-R. & Wu, C-L., 2007 Feb 1, In : Arthritis and Rheumatism. 56, 2, p. 544-554 11 p.

Research output: Contribution to journalArticle

139 Citations (Scopus)

Amelioration of experimental arthritis by a telomerase-dependent conditionally replicating adenovirus that targets synovial fibroblasts

Chen, S. Y., Shiau, A-L., Shieh, G. S., Su, C. H., Lee, C. H., Lee, H. L., Wang, C-R. & Wu, C-L., 2009 Nov 1, In : Arthritis and Rheumatism. 60, 11, p. 3290-3302 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
5 Citations (Scopus)

Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140-3p and 140-5p

Peng, J. S., Chen, S. Y., Wu, C. L., Chong, H. E., Ding, Y. C., Shiau, A. L. & Wang, C. R., 2016 Feb 1, In : Arthritis and Rheumatology. 68, 2, p. 370-381 12 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Amelioration of experimentally induced arthritis by reducing reactive oxygen species production through the intra-articular injection of water-soluble fullerenol

Kuo, W. S., Weng, C-T., Chen, J. H., Wu, C-L., Shiau, A-L., Hsieh, J. L., So, E. C., Wu, P-T. & Chen, S. Y., 2019 Jun, In : Nanomaterials. 9, 6, 909.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Amelioration of rat collagen-induced arthritis through CD4+ T cells apoptosis and synovial interleukin-17 reduction by indoleamine 2,3-dioxygenase gene therapy

Chen, S. Y., Wu, C. L., Lai, M. D., Lin, C. C., Yo, Y. T., Jou, I. M., Lee, C. H., Weng, C. T., Shiau, A. L. & Wang, C. R., 2011 Feb 1, In : Human Gene Therapy. 22, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
30 Citations (Scopus)

A mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infection

Wang, Y. F., Chou, C. T., Lei, H. Y., Liu, C. C., Wang, S. M., Yan, J. J., Su, I. J., Wang, J. R., Yeh, T. M., Chen, S. H. & Yu, C. K., 2004 Aug 1, In : Journal of Virology. 78, 15, p. 7916-7924 9 p.

Research output: Contribution to journalArticle

185 Citations (Scopus)

A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli

Kuo, C. J., Wang, S. T., Lin, C. M., Chiu, H. C., Huang, C. R., Lee, D. Y., Chang, G. D., Chou, T. C., Chen, J. W. & Chen, C. S., 2018 Mar 1, In : Cell Death and Disease. 9, 3, 381.

Research output: Contribution to journalArticle

3 Citations (Scopus)

A multiplex dot hybridization assay for detection and differentiation of acanthamoeba and herpes keratitis

Kuo, M. T., Fang, P. C., Yu, H. J., Chao, T. L., Chien, C. C., Chen, S. H., Wang, J. R., Tseng, S. L., Lai, Y. H., Hsiao, C. C. & Chang, T. C., 2016 Apr 1, In : Investigative Ophthalmology and Visual Science. 57, 4, p. 2158-2163 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

A murine oral enterovirus 71 infection model with central nervous system involvement

Chen, Y. C., Yu, C-K., Wang, Y. F., Liu, C-C., Su, I. J. & Lei, H. Y., 2004 Jan 1, In : Journal of General Virology. 85, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

117 Citations (Scopus)

Analysis of the expression of Fas-L in nasopharyngeal carcinoma tissues

Tsai, S. T., Fang, S. Y., Jin, Y. T., Su, I. J. & Yang, B. C., 1999 Jul 1, In : Oral Oncology. 35, 4, p. 421-424 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

An ancova approach to normalize microarray data, and its performance to existing methods

Chan, S. H., Chen, L. J., Chow, N. H. & Liu, H. S., 2005 Apr 1, In : Journal of Bioinformatics and Computational Biology. 3, 2, p. 257-268 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Angiostatin antagonizes the action of VEGF-A in human endothelial cells via two distinct pathways

Chen, Y. H., Wu, H. L., Chen, C. K., Huang, Y. H., Yang, B. C. & Wu, L. W., 2003 Oct 24, In : Biochemical and Biophysical Research Communications. 310, 3, p. 804-810 7 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

An increase in integrin-linked kinase noncanonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2

Tseng, P. C., Chen, C. L., Shan, Y. S., Chang, W. T., Liu, H. S., Hong, T. M., Hsieh, C. Y., Lin, S. H. & Lin, C. F., 2014 Jan 1, In : Cell Communication and Signaling. 12, 1, 69.

Research output: Contribution to journalArticle

7 Citations (Scopus)

An integrated microfluidic platform for rapid detection and subtyping of influenza viruses from clinical samples

Tai, C. H., Tsai, Y. C., Wang, C. H., Ho, T. S., Chang, C. P. & Lee, G. B., 2014 Mar, In : Microfluidics and Nanofluidics. 16, 3, p. 501-512 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

An iron-binding protein, Dpr, decreases hydrogen peroxide stress and protects Streptococcus pyogenes against multiple stresses

Tsou, C. C., Chiang-Ni, C., Lin, Y. S., Chuang, W. J., Lin, M. T., Liu, C. C. & Wu, J. J., 2008 Sep 1, In : Infection and Immunity. 76, 9, p. 4038-4045 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Annexin A2 on lung epithelial cell surface is recognized by severe acute respiratory syndrome-associated coronavirus spike domain 2 antibodies

Fang, Y. T., Lin, C. F., Liao, P. C., Kuo, Y. M., Wang, S., Yeh, T. M., Shieh, C. C. K., Su, I. J., Lei, H. Y. & Lin, Y. S., 2010 Feb 1, In : Molecular Immunology. 47, 5, p. 1000-1009 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Annexin A2 silencing induces G2 arrest of non-small cell lung cancer cells through p53-dependent and -independent mechanisms

Wang, C. Y., Chen, C. L., Tseng, Y. L., Fang, Y. T., Lin, Y. S., Su, W. C., Chen, C. C., Chang, K. C., Wang, Y. C. & Lin, C. F., 2012 Sep 21, In : Journal of Biological Chemistry. 287, 39, p. 32512-32524 13 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

A Non-biotin Polymerized Horseradish-peroxidase Method for the Immunohistochemical Diagnosis of Canine Distemper

Liang, C. T., Chueh, L. L., Pang, V. F., Zhuo, Y. X., Liang, S. C., Yu, C-K., Chiang, H., Lee, C. C. & Liu, C. H., 2007 Jan 1, In : Journal of Comparative Pathology. 136, 1, p. 57-64 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA

Yen, M. C., Lin, C. C., Chen, Y. L., Huang, S. S., Yang, H. J., Chang, C. P., Lei, H. Y. & Lai, M. D., 2009 Jan 15, In : Clinical Cancer Research. 15, 2, p. 641-649 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

A novel natural tautomeric pair of garcinielliptone FC suppressed nuclear factor κB and induced apoptosis in human colorectal cancer cells

Won, S. J., Lin, T. Y., Yen, C. H., Tzeng, Y. H., Liu, H. S., Lin, C. N., Yu, C. H., Wu, C. S., Chen, J. T., Chen, Y. T., Huang, C. Y. F. & Su, C. L., 2016 Jun 1, In : Journal of Functional Foods. 24, p. 568-578 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)