Research Output 1990 2019

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2019

An effective and accurate identification system of Mycobacterium tuberculosis using convolution neural networks

Kuok, C. P., Horng, M. H., Liao, Y. M., Chow, N-H. & Sun, Y-N., 2019 Jun 1, In : Microscopy Research and Technique. 82, 6, p. 709-719 11 p.

Research output: Contribution to journalArticle

tuberculosis
system identification
Convolution
Mycobacterium tuberculosis
convolution integrals

Comprehensive assessment of HER2 alteration in a colorectal cancer cohort: From next-generation sequencing to clinical significance

Yeh, Y. M., Lee, C. H., Chen, S. H., Lee, C. T., Lin, B. W., Lin, S. C., Chan, R. H., Lee, J. C., Shen, M. R. & Lin, P. C., 2019 Jan 1, In : Cancer Management and Research. 11, p. 7867-7875 9 p.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
oxaliplatin
human ERBB2 protein
Fluorescence In Situ Hybridization
Therapeutics

Fully galactosyl-fucosyl-bisected IgG 1 reduces anti-HBV efficacy and liver histological improvement

Ho, C. H., Chen, S-H., Tsai, H-W., Wu, I-C. & Chang, T-T., 2019 Mar 1, In : Antiviral Research. 163, p. 1-10 10 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Immunoglobulin G
Liver
Hepatitis B e Antigens
Acetylglucosamine

H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer

Yeh, Y. C., Kuo, H. Y., Chang, W. L., Yang, H. B., Lu, C. C., Cheng, H. C., Wu, M. S. & Sheu, B. S., 2019 Jan 5, In : Journal of biomedical science. 26, 1, 4.

Research output: Contribution to journalArticle

Pylorus
Polymorphism
Stomach Neoplasms
Amino Acid Sequence
Amino Acids

Hematoxylin and Eosin (H&E) Stained Liver Portal Area Segmentation Using Multi-Scale Receptive Field Convolutional Neural Network

Xiao, Q. E., Chung, P. C., Tsai, H. W., Cheng, K. S., Chow, N. H., Juang, Y. Z., Tsai, H. H., Wang, C. H. & Hsieh, T. A., 2019 Jan 1, (Accepted/In press) In : IEEE Journal on Emerging and Selected Topics in Circuits and Systems.

Research output: Contribution to journalArticle

Liver
Neural networks
Ducts
Feature extraction
Entropy
Aplastic Anemia
Databases
Incidence
Population
Survival

Liquid biopsy for detection of EGFR T790M mutation in nonsmall cell lung cancer: An experience of proficiency testing in Taiwan

Ho, H. L., Huang, C. C., Ku, W. H., Ho, C-L., Lin, C. H., Yu, S. L. & Chou, T. Y., 2019 Jan 1, In : Journal of the Chinese Medical Association. 82, 6, p. 473-476 4 p.

Research output: Contribution to journalArticle

Taiwan
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Biopsy
Mutation
2 Citations (Scopus)

MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway

Chu, C. A., Lee, C. T., Lee, J. C., Wang, Y. W., Huang, C. T., Lan, S. H., Lin, P. C., Lin, B. W., Tian, Y. F., Liu, H. S. & Chow, N. H., 2019 May, In : EBioMedicine. 43, p. 270-281 12 p.

Research output: Contribution to journalArticle

Open Access
Class III Phosphatidylinositol 3-Kinases
Autophagy
Tumors
Colorectal Neoplasms
Genes

Plasma proteome plus site-specific N-glycoprofiling for hepatobiliary carcinomas

Chang, T-T., Cheng, J. H., Tsai, H-W., Young, K-C., Hsieh, S-Y. & Ho, C. H., 2019 Jul 1, In : Journal of Pathology: Clinical Research. 5, 3, p. 199-212 14 p.

Research output: Contribution to journalArticle

Open Access
Proteome
Complement C3
Carcinoma
Hepatocellular Carcinoma
Cholangiocarcinoma

Pulmonary alveolar proteinosis with upper-lobe predominance in a non-smoking female

Er, H. P., Lee, C-T. & Huang, T-H., 2019 Aug 1, In : Respirology Case Reports. 7, 6, e00445.

Research output: Contribution to journalArticle

Open Access
Pulmonary Alveolar Proteinosis
Lung
Glass
Spirometry
Immune System Diseases

Real-world outcomes of NSCLC patients receiving tissue or circulating tumor DNA-guided osimertinib treatment

Su, P. L., Yang, S. C., Chen, Y. L., Wu, Y. L., Lin, C. Y., Chang, W. Y., Tseng, Y. L., Lai, W. W., Ho, C. L., Lin, C. C. & Su, W. C., 2019 Oct 1, In : Cancer medicine. 8, 13, p. 5939-5947 9 p.

Research output: Contribution to journalArticle

Open Access
DNA
Neoplasms
Mutation
Disease-Free Survival
Therapeutics
1 Citation (Scopus)
Metaplasia
Helicobacter pylori
Stomach Neoplasms
MicroRNAs
spasmolytic polypeptide

The differential distributions of ASPM isoforms and their roles in Wnt signaling, cell cycle progression, and pancreatic cancer prognosis

Hsu, C. C., Liao, W. Y., Chan, T. S., Chen, W. Y., Lee, C. T., Shan, Y. S., Huang, P. J., Hou, Y. C., Li, C. R. & Tsai, K. K., 2019 Dec 1, In : Journal of Pathology. 249, 4, p. 498-508 11 p.

Research output: Contribution to journalArticle

Open Access
Microcephaly
Pancreatic Neoplasms
Cell Cycle
Protein Isoforms
Adenocarcinoma
2018
1 Citation (Scopus)

A Newly Recognized Histologic Pattern of IgG4-related Lymphadenopathy: Expanding the Morphologic Spectrum

Chen, Y. R., Chen, Y. J., Wang, M. C., Medeiros, L. J. & Chang, K. C., 2018 Jan 1, In : American Journal of Surgical Pathology. 42, 7, p. 977-982 6 p.

Research output: Contribution to journalArticle

Immunoglobulin G
Lymphocytes
Plasma Cell Granuloma
Infectious Mononucleosis
Histiocytes

Cutaneous lymphomas in Taiwan: A review of 118 cases from a medical center in southern Taiwan

Lee, C. N., Hsu, C-K., Chang, K-C., Wu, C. L., Chen, T-Y. & Lee, Y-Y., 2018 Mar 1, In : Dermatologica Sinica. 36, 1, p. 16-24 9 p.

Research output: Contribution to journalArticle

Mycosis Fungoides
Taiwan
Lymphoma
Skin
Extranodal NK-T-Cell Lymphoma
3 Citations (Scopus)
Pulmonary Hypertension
Pulmonary Artery
Glucagon-Like Peptides
Heart Ventricles
Lung
2 Citations (Scopus)
Cholangiocarcinoma
Immunoglobulin G
Macrophages
Neoplasm Metastasis
Recurrence

Ground glass hepatocytes provide targets for therapy or prevention of hepatitis B virus-related hepatocellular carcinoma

Chang, H., Tsai, H., Teng, C., Hui-ching Wang, L., Huang, W. & Su, I., 2018 Mar 1, In : AIMS Medical Science. 5, 2, p. 90-101

Research output: Contribution to journalArticle

5 Citations (Scopus)

Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C. J., Ai, Y. L., Tsai, H. W., Chan, S. H., Yen, C. S., Cheng, K. H., Lee, Y. P., Kao, C. W., Wang, Y. C., Chen, Y. L., Lin, C. H., Liu, T., Tsai, H. P., Wang, J. R., Su, I. J. & Huang, W., 2018 Sep, In : Hepatology. 68, 3, p. 815-826 12 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Biomarkers
Recurrence
Surface Antigens
3 Citations (Scopus)

Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis

Li, T. N., Wu, Y. J., Tsai, H. W., Sun, C. P., Wu, Y. H., Wu, H. L., Pei, Y. N., Lu, K. Y., Yen, T. T. C., Chang, C. W., Chan, H. L., Tao, M. H., Liou, J. Y., Chang, M. D. T., Su, I. J. & Wang, L. H. C., 2018 Aug, In : Journal of Pathology. 245, 4, p. 502-513 12 p.

Research output: Contribution to journalArticle

Cytokinesis
Surface Antigens
Hepatitis B virus
Hepatocytes
DNA Damage
2 Citations (Scopus)

Liver regeneration accelerates hepatitis B virus-related tumorigenesis of hepatocellular carcinoma

Teng, C. F., Chang, H. Y., Tsai, H-W., Hsieh, W. C., Kuo, Y. H., Su, I. J. & Lin, Y-J., 2018 Jun 1, In : Molecular Oncology. 12, 7, p. 1175-1187 13 p.

Research output: Contribution to journalArticle

Liver Regeneration
Hepatectomy
Hepatitis B virus
Hepatocellular Carcinoma
Carcinogenesis
Mixed Connective Tissue Disease
Interstitial Lung Diseases
Idiopathic Interstitial Pneumonias
Autoimmune Diseases
10 Citations (Scopus)

Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway

Chu, P. C., Lin, P-C., Wu, H. Y., Lin, K. T., Wu, C., Bekaii-Saab, T., Lin, Y-J., Lee, C-T., Lee, J-C. & Chen, C. S., 2018 Jun 1, In : Oncogene. 37, 25, p. 3440-3455 16 p.

Research output: Contribution to journalArticle

Y-Box-Binding Protein 1
IGF Type 1 Receptor
Mitogen-Activated Protein Kinase Kinases
Colorectal Neoplasms
Neoplasm Metastasis
1 Citation (Scopus)
Aortic Valve
3 Citations (Scopus)
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Neoplasm Metastasis
Mutation
Brain
1 Citation (Scopus)
Progesterone Receptors
Hepatocellular Carcinoma
Biomarkers
Membranes
Atlases
2 Citations (Scopus)
Systemic Lupus Erythematosus
Hemorrhage
Extracorporeal Membrane Oxygenation
Plasmapheresis
Methylprednisolone

The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes

Wang, Y. C., Chang, K-C., Lin, P-W., Lee, J-C., Lai, C. H., Lin, L. J., Yen, Y., Lin, C. S., Yang, S. J., Lin, P-C., Lee, C-T. & Hung, L-Y., 2018 Jun 1, In : Experimental and Molecular Medicine. 50, 6, 70.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
cdc Genes
Epidermal Growth Factor
Carcinogenesis
Genes
2017
22 Citations (Scopus)

ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma

Lee, J. C., Li, C. F., Huang, H. Y., Zhu, M. J., Mariño-Enríquez, A., Lee, C. T., Ou, W. B., Hornick, J. L. & Fletcher, J. A., 2017 Feb 1, In : Journal of Pathology. 241, 3, p. 316-323 8 p.

Research output: Contribution to journalArticle

Oncogene Proteins
Sarcoma
Neoplasms
Immunoprecipitation
Electrophoresis
4 Citations (Scopus)
Term Birth
Neuroendocrine Carcinoma
Small Cell Carcinoma
Cervix Uteri
Fertility

CD68-negative nonlipidized juvenile xanthogranuloma

Lo, T. K., Chang, K-C., Chu, C-B. & Lee, Y-Y., 2017 Sep 1, In : Dermatologica Sinica. 35, 3, p. 142-144 3 p.

Research output: Contribution to journalArticle

Juvenile Xanthogranuloma
Factor XIIIa
Non-Langerhans-Cell Histiocytosis
Foam Cells
Forehead
7 Citations (Scopus)

Epstein–Barr virus latent membrane protein-1 up-regulates cytokines and correlates with older age and poorer prognosis in Hodgkin lymphoma

Chang, K-C., Chen, P. C. H., Chang, Y., Wu, Y. H., Chen, Y-P., Lai, C. H., Jeffrey Medeiros, L., Su, I. J. & Wang, H. W., 2017 Feb 1, In : Histopathology. 70, 3, p. 442-455 14 p.

Research output: Contribution to journalArticle

Macrophage Inflammatory Proteins
Hodgkin Disease
Membrane Proteins
Up-Regulation
Cytokines
1 Citation (Scopus)
Hepatitis B e Antigens
Immunoglobulin G
Hepatitis B virus
Serum
Therapeutics
3 Citations (Scopus)

Hepatocellular carcinoma-associated single-nucleotide variants and deletions identified by the use of genome-wide high-throughput analysis of hepatitis B virus

Liu, W. C., Wu, I. C., Lee, Y. C., Lin, C. P., Cheng, J. H., Lin, Y. J., Yen, C. J., Cheng, P. N., Li, P. F., Cheng, Y. T., Cheng, P. W., Sun, K. T., Yan, S. L., Lin, J. J., Yang, J. C., Chang, K. C., Ho, C. H., Tseng, V. S., Chang, B. C. H., Wu, J. C. & 1 others, Chang, T. T., 2017 Oct 1, In : Journal of Pathology. 243, 2, p. 176-192 17 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Nucleotides
Genome
Meta-Analysis
2 Citations (Scopus)

Immunohistochemical studies and fluorodeoxyglucose uptake on positron emission tomography in pharyngeal cancer for predicting radiotherapy-based treatment outcomes

Lin, Y. C., Chen, R. Y., Chen, S. W., Hsieh, T. C., Yen, K. Y., Liang, J. A., Yang, S. N., Wang, Y. C., Chen, Y. H., Chow, N-H. & Kao, C. H., 2017 Jun 1, In : Clinical Otolaryngology. 42, 3, p. 608-619 12 p.

Research output: Contribution to journalArticle

Pharyngeal Neoplasms
Positron-Emission Tomography
Vascular Endothelial Growth Factor A
Radiotherapy
Tumor Burden
21 Citations (Scopus)

Liquid biopsy genotyping in lung cancer: Ready for clinical utility?

Huang, W. L., Chen, Y. L., Yang, S. C., Ho, C. L., Wei, F., Wong, D. T., Su, W. C. & Lin, C. C., 2017 Jan 1, In : Oncotarget. 8, 11, p. 18590-18608 19 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Lung Neoplasms
Biopsy
DNA
Hematologic Tests

Low-cell-number, single-tube amplification (STA) of total RNA revealed transcriptome changes from pluripotency to endothelium

Lee, Y. H., Hsueh, Y. W., Peng, Y. H., Chang, K. C., Tsai, K. J., Sun, H. S., Su, I. J. & Chiang, P. M., 2017 Mar 21, In : BMC Biology. 15, 1, 22.

Research output: Contribution to journalArticle

endothelium
Transcriptome
transcriptome
Endothelium
Amplification
1 Citation (Scopus)
Pylorus
Medical problems
Type 2 Diabetes Mellitus
Stomach
Inflammation
10 Citations (Scopus)

Oleic acid-induced ANGPTL4 enhances head and neck squamous cell carcinoma anoikis resistance and metastasis via up-regulation of fibronectin

Shen, C. J., Chan, S-H., Lee, C-T., Huang, W. C., Tsai, J. P. & Chen, B-K., 2017 Feb 1, In : Cancer Letters. 386, p. 110-122 13 p.

Research output: Contribution to journalArticle

Anoikis
Oleic Acid
Fibronectins
Up-Regulation
Neoplasm Metastasis
2 Citations (Scopus)

Osteopontin polymorphism increases gastric precancerous intestinal metaplasia susceptibility in Helicobacter pylori infected male

Chang, W-L., Lin, M-Y., Kuo, H. Y., Yang, H. B., Cheng, H-C., Lu, C-C. & Sheu, B-S., 2017 Jul 1, In : Future Oncology. 13, 16, 0006.

Research output: Contribution to journalArticle

Osteopontin
Metaplasia
Helicobacter pylori
Stomach
Haplotypes
1 Citation (Scopus)
Ankylosing Spondylitis
Inflammatory Bowel Diseases
Colitis
Sulfasalazine
Hip Joint
6 Citations (Scopus)
Mucinous Adenocarcinoma
Adenocarcinoma
CpG Islands
Survival
Phenotype
4 Citations (Scopus)

Serum Level of Trefoil Factor 2 can Predict the Extent of Gastric Spasmolytic Polypeptide-Expressing Metaplasia in the H. pylori-Infected Gastric Cancer Relatives

Kuo, H. Y., Chang, W. L., Yeh, Y. C., Tsai, Y. C., Wu, C. T., Cheng, H. C., Yang, H. B., Lu, C. C. & Sheu, B. S., 2017 Feb 1, In : Helicobacter. 22, 1, e12320.

Research output: Contribution to journalArticle

Pylorus
Metaplasia
Stomach Neoplasms
Stomach
Serum
1 Citation (Scopus)

Squamoid morules in the pseudoinvasive foci of colonic polyp morphologically mimic invasive carcinoma

Lee, H. E., Chandan, V. S., Lee, C-T. & Wu, T. T., 2017 Oct 1, In : Human Pathology. 68, p. 54-60 7 p.

Research output: Contribution to journalArticle

Colonic Polyps
Polyps
Keratin-6
Keratin-5
Adenoma

StemTextSearch: Stem cell gene database with evidence from abstracts

Chen, C. C. & Ho, C. L., 2017 May 1, In : Journal of Biomedical Informatics. 69, p. 150-159 10 p.

Research output: Contribution to journalArticle

Stem cells
Stem Cells
Genes
Databases
Data Mining
5 Citations (Scopus)
Levofloxacin
Helicobacter pylori
Type 2 Diabetes Mellitus
Clarithromycin
Helicobacter Infections
4 Citations (Scopus)

TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1

Huang, P. H., Lu, P. J., Ding, L. Y., Chu, P. C., Hsu, W. Y., Chen, C. S., Tsao, C. C., Chen, B. H., Lee, C. T., Shan, Y. S. & Chen, C. S., 2017 Apr 20, In : Oncogene. 36, 16, p. 2202-2214 13 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Epigenomics
Phenotype
Epithelial-Mesenchymal Transition
gemcitabine
5 Citations (Scopus)

The corpus-predominant gastritis index can be an early and reversible marker to identify the gastric cancer risk of Helicobacter pylori-infected nonulcer dyspepsia

Cheng, H. C., Tsai, Y. C., Yang, H. B., Yeh, Y. C., Chang, W. L., Kuo, H. Y., Lu, C. C. & Sheu, B. S., 2017 Aug, In : Helicobacter. 22, 4, e12385.

Research output: Contribution to journalArticle

Dyspepsia
Gastritis
Helicobacter pylori
Stomach Neoplasms
Metaplasia
4 Citations (Scopus)

The role of Lutheran/basal cell adhesion molecule in human bladder carcinogenesis

Chang, H. Y., Chang, H. M., Wu, T. J., Chaing, C. Y., Tzai, T. S., Cheng, H-L., Raghavaraju, G., Chow, N-H. & Liu, H-S., 2017 Aug 26, In : Journal of biomedical science. 24, 1, 61.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Carcinogenesis
Urinary Bladder
Cell adhesion
Cell Adhesion
6 Citations (Scopus)

Translational upregulation of Aurora-A by hnRNP Q1 contributes to cell proliferation and tumorigenesis in colorectal cancer

Lai, C. H., Huang, Y. C., Lee, J-C., Tseng, T-C., Chang, K-C., Chen, Y. J., Ding, N. J., Huang, P. H., Chang, W. C., Lin, P-W., Chen, R. Y., Wang, Y. C., Lai, Y. C. & Hung, L-Y., 2017 Jan 1, In : Cell Death and Disease. 8, 1, e2555.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
Colorectal Neoplasms
Carcinogenesis
Up-Regulation
Cell Proliferation