Research Output 1990 2020

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2015
17 Citations (Scopus)

Proton-Pump Inhibitor Exposure Aggravates Clostridium difficile-Associated Colitis: Evidence from a Mouse Model

Hung, Y. P., Ko, W. C., Chou, P. H., Chen, Y. H., Lin, H. J., Liu, Y. H., Tsai, H. W., Lee, J. C. & Tsai, P. J., 2015 Aug 15, In : Journal of Infectious Diseases. 212, 4, p. 654-663 10 p.

Research output: Contribution to journalArticle

Clostridium difficile
Proton Pump Inhibitors
Colitis
Clostridium Infections
Pseudomembranous Enterocolitis
10 Citations (Scopus)

Ras induces experimental lung metastasis through up-regulation of RbAp46 to suppress RECK promoter activity

Yeh, H. H., Tseng, Y. F., Hsu, Y. C., Lan, S. H., Wu, S. Y., Raghavaraju, G., Cheng, D. E., Lee, Y. R., Chang, T. Y., Chow, N. H., Hung, W. C. & Liu, H-S., 2015 Mar 25, In : BMC Cancer. 15, 1, 172.

Research output: Contribution to journalArticle

Up-Regulation
Urinary Bladder Neoplasms
Neoplasm Metastasis
Lung
Genes
11 Citations (Scopus)

SH3BGRL3 Protein as a Potential Prognostic Biomarker for Urothelial Carcinoma: A Novel Binding Partner of Epidermal Growth Factor Receptor

Chiang, C. Y., Pan, C. C., Chang, H. Y., Lai, M-D., Tzai, T. S., Tsai, Y-S., Ling, P., Liu, H-S., Lee, B-F., Cheng, H-L., Ho, C-L., Chen, S-H. & Chow, N-H., 2015 Dec 15, In : Clinical Cancer Research. 21, 24, p. 5601-5611 11 p.

Research output: Contribution to journalArticle

src Homology Domains
Epidermal Growth Factor Receptor
Glutamic Acid
Biomarkers
Carcinoma
26 Citations (Scopus)

The cAMP responsive element binding protein 1 transactivates epithelial membrane protein 2, a potential tumor suppressor in the urinary bladder urothelial carcinoma

Li, C. F., Wu, W. J., Wu, W. R., Liao, Y. J., Chen, L. R., Huang, C. N., Li, C. C., Li, W. M., Huang, H. Y., Chen, Y. L., Liang, S. S., Chow, N. H. & Shiue, Y. L., 2015 Jan 1, In : Oncotarget. 6, 11, p. 9220-9239 20 p.

Research output: Contribution to journalArticle

Carrier Proteins
Urinary Bladder
Genistein
Carcinoma
Neoplasms
17 Citations (Scopus)
Transforming Growth Factors
Superoxides
Hepatocellular Carcinoma
Cells
Hep G2 Cells
2 Citations (Scopus)

TRC8 downregulation contributes to the development of non-alcoholic steatohepatitis by exacerbating hepatic endoplasmic reticulum stress

Chang, P. C., Tsai, H. W., Chiang, M. T., Huang, P. L., Shyue, S. K. & Chau, L. Y., 2015 Nov 1, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 11, p. 2339-2351 13 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Fatty Liver
Down-Regulation
Choline
Methionine
15 Citations (Scopus)

Upregulation of MicroRNA-19b predicts good prognosis in patients with hepatocellular carcinoma presenting with vascular invasion or multifocal disease

Hung, C. L., Yen, C. S., Tsai, H-W., Su, Y. C. & Yen, C-J., 2015 Oct 9, In : BMC Cancer. 15, 1, 665.

Research output: Contribution to journalArticle

MicroRNAs
Blood Vessels
Hepatocellular Carcinoma
Up-Regulation
Mitogen-Activated Protein Kinase 14
2014
23 Citations (Scopus)

A nanopatterned cell-seeded cardiac patch prevents electro-uncoupling and improves the therapeutic efficacy of cardiac repair

Lin, Y. D., Ko, M. C., Wu, S. T., Li, S. F., Hu, J. F., Lai, Y. J., Harn, H. I. C., Laio, I. C., Yeh, M. L., Yeh, H. I., Tang, M. J., Chang, K. C., Su, F. C., Wei, E. I. H., Lee, S. T., Chen, J. H., Hoffman, A. S., Wu, W. T. & Hsieh, P. C. H., 2014 Apr, In : Biomaterials Science. 2, 4, p. 567-580 14 p.

Research output: Contribution to journalArticle

Endothelial cells
Repair
Anisotropy
Medical nanotechnology
Hemodynamics
2 Citations (Scopus)

An electromagnetic thermotherapy system with a deep penetration depth for percutaneous thermal ablation

Huang, S. C., Chang, Y. Y., Kang, J. W., Tsai, H. W., Shan, Y. S., Lin, X. Z. & Lee, G. B., 2014 Jan 1, In : Annals of biomedical engineering. 42, 1, p. 86-96 11 p.

Research output: Contribution to journalArticle

Ablation
Needles
Electromagnetic fields
Animals
Tissue
8 Citations (Scopus)

Anti-apoptotic effects of osteopontin through the up-regulation of Mcl-1 in gastrointestinal stromal tumors

Hsu, K. H., Tsai, H-W., Lin, P. W., Hsu, Y. S., Lu, P-J. & Shan, Y-S., 2014 Jun 20, In : World Journal of Surgical Oncology. 12, 1, 189.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Osteopontin
Up-Regulation
Catenins
Apoptosis
5 Citations (Scopus)

CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors

Chen, Y. P., Lin, H. J., Chen, J. S., Tsai, M. Y., Hsieh, H. P., Chang, J. Y., Chen, N. F., Chang, K. C., Huang, W. T., Su, W. C., Yang, S. T., Chang, W. C., Hung, L. Y. & Chen, T. Y., 2014 Aug 1, In : International Journal of Cancer. 135, 3, p. 751-762 12 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Aurora Kinases
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Cell Line
Pharmaceutical Preparations
2 Citations (Scopus)

Detection and distribution of endogenous steroids in human stratum corneum

Tseng, S. P., Lu, C-C., Liao, P-C., Chou, C-H., Sheu, H. M. & Tsai, J-C., 2014 Mar 1, In : Dermatologica Sinica. 32, 1, p. 19-24 6 p.

Research output: Contribution to journalArticle

Cortisone
Cornea
Steroids
Hydrocortisone
Forearm
6 Citations (Scopus)

Efficacy of entecavir in chronic hepatitis B patients with persistently normal alanine aminotransferase: Randomized, double-blind, placebo-controlled study

Tseng, K. C., Chen, C. Y., Tsai, H. W., Chang, T. T., Chuang, W. L., Hsu, P. I., Liu, W. C. & Cheng, P. N., 2014, In : Antiviral Therapy. 19, 8, p. 755-764 10 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Alanine Transaminase
Placebos
DNA
Histology
2 Citations (Scopus)

Electromagnetic thermotherapy for deep organ ablation by using a needle array under a synchronized-coil system

Huang, S. C., Kang, J-W., Tsai, H-W., Shan, Y-S., Lin, X-Z. & Lee, G. B., 2014 Nov 1, In : IEEE Transactions on Biomedical Engineering. 61, 11, p. 2733-2739 7 p., 6860281.

Research output: Contribution to journalArticle

Ablation
Needles
Electromagnetic fields
Surgery
Tumors
4 Citations (Scopus)

Electromagnetic thermotherapy system with needle arrays: A practical tool for the removal of cancerous tumors

Huang, S. C., Kang, J. W., Tsai, H. W., Shan, Y. S., Lin, X. Z. & Lee, G. B., 2014 Feb 1, In : IEEE Transactions on Biomedical Engineering. 61, 2, p. 598-605 8 p., 6645388.

Research output: Contribution to journalArticle

Needles
Tumors
Oncology
Medical applications
Ablation
12 Citations (Scopus)
T-Cell Lymphoma
Human Herpesvirus 4
B-Lymphocytes
T-Lymphocytes
Virus Latency
5 Citations (Scopus)

Factors Predicting recurrence and postrecurrence survival in completely resected thymic carcinoma

Yen, Y. T., Lai, W. W., Chang, K. W., Chang, K. C., Lee, S. C., Lin, S. H., Wu, M. H. & Tseng, Y. L., 2014 Apr, In : Annals of Thoracic Surgery. 97, 4, p. 1169-1175 7 p.

Research output: Contribution to journalArticle

Thymoma
Recurrence
Survival
Superior Vena Cava
Disease-Free Survival
19 Citations (Scopus)

Ground-glass hepatocytes co-expressing hepatitis B virus X protein and surface antigens exhibit enhanced oncogenic effects and tumorigenesis

Wu, H. C., Tsai, H-W., Teng, C. F., Hsieh, W. C., Lin, Y-J., Wang, L. H. C., Yuan, Q. & Su, I. J., 2014 Jan 1, In : Human Pathology. 45, 6, p. 1294-1301 8 p.

Research output: Contribution to journalArticle

Surface Antigens
Glass
Hepatocytes
Carcinogenesis
Mitogen-Activated Protein Kinase 3
4 Citations (Scopus)
Chronic Hepatitis B
Hepatitis B Surface Antigens
Liver
Hepatitis B e Antigens
Mutation
8 Citations (Scopus)

Hematopathologic discrepancies between referral and review diagnoses: A gap between general pathologists and hematopathologists

Chang, C., Huang, S. W., Su, I. J. & Chang, K-C., 2014 Jan 1, In : Leukemia and Lymphoma. 55, 5, p. 1023-1030 8 p.

Research output: Contribution to journalArticle

Lymphoma
Referral and Consultation
Natural Killer T-Cells
Disease Management
Taiwan
13 Citations (Scopus)

High-mobility group AT-hook 2: An independent marker of poor prognosis in intrahepatic cholangiocarcinoma

Lee, C. T., Wu, T. T., Lohse, C. M. & Zhang, L., 2014 Nov 1, In : Human Pathology. 45, 11, p. 2334-2340 7 p.

Research output: Contribution to journalArticle

AT-Hook Motifs
Cholangiocarcinoma
Fetal Proteins
Survival
Neoplasms
17 Citations (Scopus)

Hypoxia promotes nuclear translocation and transcriptional function in the oncogenic tyrosine kinase RON

Chang, H. Y., Liu, H. S., Lai, M. D., Tsai, Y. S., Tzai, T. S., Cheng, H. L. & Chow, N. H., 2014 Aug 15, In : Cancer Research. 74, 16, p. 4549-4562 14 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Neoplasms
Cell Survival
Hypoxia-Inducible Factor 1
Receptor Protein-Tyrosine Kinases
49 Citations (Scopus)

MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo

Hsu, T. I., Hsu, C. H., Lee, K. H., Lin, J. T., Chen, C. S., Chang, K. C., Su, C. Y. J., Hsiao, M. & Lu, P. J., 2014 Jan 1, In : Oncogenesis. 3, 4, e99.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
MicroRNAs
Prostatic Neoplasms
Carcinogenesis
Neoplasms
74 Citations (Scopus)

MiR-320 regulates tumor angiogenesis driven by vascular endothelial cells in oral cancer by silencing neuropilin 1

Wu, Y. Y., Chen, Y. L., Jao, Y. C., Hsieh, I. S., Chang, K. C. & Hong, T. M., 2014 Jan 1, In : Angiogenesis. 17, 1, p. 247-260 14 p.

Research output: Contribution to journalArticle

Neuropilin-1
Mouth Neoplasms
Endothelial cells
Tumors
Endothelial Cells
32 Citations (Scopus)

Monoclonality and cytogenetic abnormalities in hyaline vascular Castleman disease

Chang, K-C., Wang, Y. C., Hung, L-Y., Huang, W. T., Tsou, J. H., M Jones, D., Song, H. L., Yeh, Y-M., Kao, L. Y. & Medeiros, L. J., 2014 Jan 1, In : Modern Pathology. 27, 6, p. 823-831 9 p.

Research output: Contribution to journalArticle

Giant Lymph Node Hyperplasia
Hyalin
Vascular Diseases
Chromosome Aberrations
T-Lymphocyte Gene Rearrangement
2 Citations (Scopus)
Urethral Neoplasms
Multiple Primary Neoplasms
Marginal Zone B-Cell Lymphoma
Urinary Bladder Neoplasms
Urinary Bladder
73 Citations (Scopus)

Noninvasive saliva-based EGFR gene mutation detection in patients with lung cancer

Wei, F., Lin, C. C., Joon, A., Feng, Z., Troche, G., Lira, M. E., Chia, D., Mao, M., Ho, C. L., Su, W. C. & Wong, D. T. W., 2014 Nov 15, In : American Journal of Respiratory and Critical Care Medicine. 190, 10, p. 1117-1126 10 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Saliva
Epidermal Growth Factor Receptor
Lung Neoplasms
Mutation
9 Citations (Scopus)

Overexpression of Aurora-C interferes with the spindle checkpoint by promoting the degradation of Aurora-B

Lin, B. W., Wang, Y. C., Chang-Liao, P. Y., Lin, Y. J., Yang, S. T., Tsou, J. H., Chang, K. C., Liu, Y. W., Tseng, J. T., Lee, C. T., Lee, J. C. & Hung, L. Y., 2014 Mar, In : Cell Death and Disease. 5, 3, e1106.

Research output: Contribution to journalArticle

M Phase Cell Cycle Checkpoints
Aurora Kinase B
Nocodazole
Neoplasms
Chromosome Segregation
14 Citations (Scopus)

Potential significance of EMP3 in patients with upper urinary tract urothelial carcinoma: Crosstalk with ErbB2-PI3K-Akt pathway

Wang, Y. W., Li, W. M., Wu, W. J., Chai, C. Y., Liu, H. S., Lai, M. D. & Chow, N. H., 2014 Jul, In : Journal of Urology. 192, 1, p. 242-251 10 p.

Research output: Contribution to journalArticle

Urinary Tract
Phosphatidylinositol 3-Kinases
Carcinoma
Cell Adhesion
Cell Movement
3 Citations (Scopus)

Susceptibility to pediatric Helicobacter pylori infection correlates with the host responses of regulatory and effector T cells

Yang, Y. J., Chuang, C. C., Yang, H. B., Lu, C. C. & Sheu, B. S., 2014 Jan 1, In : Pediatric Infectious Disease Journal. 33, 12, p. 1277-1282 6 p.

Research output: Contribution to journalArticle

Helicobacter Infections
Regulatory T-Lymphocytes
Helicobacter pylori
Eragrostis
Pediatrics
6 Citations (Scopus)

Verification of wild-type EGFR status in non-small cell lung carcinomas using a mutant-enriched PCR on selected cases

Chen, Y. L., Lu, C-C., Yang, S. C., Su, W-P., Lin, Y. L., Chen, W. L., Huang, W-Y., Su, W-C., Chow, N-H. & Ho, C-L., 2014 Jan 1, In : Journal of Molecular Diagnostics. 16, 5, p. 486-494 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Peptide Nucleic Acids
Polymerase Chain Reaction
Mutation
DNA
2013
28 Citations (Scopus)

A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression

Wang, W. Y., Hsu, C. C., Wang, T. Y., Li, C. R., Hou, Y. C., Chu, J. M., Lee, C. T., Liu, M. S., Su, J. J. M., Jian, K. Y., Huang, S. S., Jiang, S. S., Shan, Y. S., Lin, P. W., Shen, Y. Y., Lee, M. T. L., Chan, T. S., Chang, C. C., Chen, C. H., Chang, I. S. & 3 others, Lee, Y. L., Chen, L. T. & Tsai, K. K., 2013 Nov, In : Gastroenterology. 145, 5, p. 1110-1120 11 p.

Research output: Contribution to journalArticle

Morphogenesis
Transcriptome
Adenocarcinoma
Neoplasms
Gene Expression
3 Citations (Scopus)
Fusion Oncogene Proteins
Jejunal Diseases
Intussusception
Fatal Outcome
Lymphoma, Large B-Cell, Diffuse
9 Citations (Scopus)

Allergic colitis in infants related to cow's milk: Clinical characteristics, pathologic changes, and immunologic findings

Yu, M. C., Tsai, C. L., Yang, Y. J., Yang, S. S., Wang, L. H., Lee, C. T., Jan, R. L. & Wang, J. Y., 2013 Feb 1, In : Pediatrics and Neonatology. 54, 1, p. 49-55 7 p.

Research output: Contribution to journalArticle

Colitis
Milk
Milk Proteins
Eosinophils
Immunoglobulin E
11 Citations (Scopus)

A novel integrated microfluidic platform to perform fluorescence in situ hybridization for chromosomal analysis

Tai, C. H., Ho, C-L., Chen, Y. L., Chen, W. L. & Lee, G. B., 2013 Dec 1, In : Microfluidics and Nanofluidics. 15, 6, p. 745-752 8 p.

Research output: Contribution to journalArticle

Microfluidics
platforms
Fluorescence
fluorescence
abnormalities
12 Citations (Scopus)

Anterior gradient 2: A novel sensitive tumor marker for metastatic oral cancer

Chen, Y. T., Ho, C. L., Chen, P. K., Chen, Y. L. & Chang, C. F., 2013 Oct 10, In : Cancer Letters. 339, 2, p. 270-278 9 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Tumor Biomarkers
Biomarkers
Neoplasm Metastasis
Gene Expression Profiling
9 Citations (Scopus)
Hepatitis B e Antigens
Chronic Hepatitis B
Hepatitis B Surface Antigens
Histology
Liver
13 Citations (Scopus)
Cyclooxygenase 2
Colorectal Neoplasms
Neoplasms
Carcinogenesis
Mucous Membrane
2 Citations (Scopus)

Cystic tuberculous pericarditis

Lin, T-W., Tsai, M. D., Roan, J-N., Tsai, H-W., Yan, J. J. & Luo, C-Y., 2013 Oct 8, In : Journal of the American College of Cardiology. 62, 15, 1 p.

Research output: Contribution to journalArticle

Tuberculous Pericarditis
CA-125 Antigen
Antitubercular Agents
Pericardium
Combination Drug Therapy
21 Citations (Scopus)
Enterovirus Infections
Chemokine CXCL10
Viral Load
Interferon-gamma
Proteins
8 Citations (Scopus)

Epithelial membrane protein 2 is a prognostic indictor for patients with urothelial carcinoma of the upper urinary tract

Wang, Y. W., Li, W. M., Wu, W. J., Chai, C. Y., Chang, T. Y., Sun, Y., Cheng, C. J., Shiue, Y. L., Su, S. J., Cheng, H. L., Liu, H. S. & Chow, N. H., 2013 Sep 1, In : American Journal of Pathology. 183, 3, p. 709-719 11 p.

Research output: Contribution to journalArticle

Urinary Tract
Membrane Proteins
Carcinoma
Integrins
Severe Combined Immunodeficiency
2 Citations (Scopus)
Stomach Rupture
Quinazolines
Remission Induction
X Ray Computed Tomography
Antineoplastic Agents
9 Citations (Scopus)

High mobility group AT-hook 2 is overexpressed in hepatoblastoma

Lee, C-T., Zhang, L., Mounajjed, T. & Wu, T. T., 2013 May 1, In : Human Pathology. 44, 5, p. 802-810 9 p.

Research output: Contribution to journalArticle

AT-Hook Motifs
Hepatoblastoma
Catenins
Hepatocellular Carcinoma
Glypicans
16 Citations (Scopus)

Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis b virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients

Hsieh, Y. H., Su, I. J., Yen, C. J., Tsai, T. F., Tsai, H. W., Tsai, H. N., Huang, Y. J., Chen, Y. Y., Ai, Y. L., Kao, L. Y., Hsieh, W. C., Wu, H. C. & Huang, W., 2013 Feb 1, In : Carcinogenesis. 34, 2, p. 475-485 11 p.

Research output: Contribution to journalArticle

Hepatitis Viruses
Histone Deacetylase Inhibitors
Oncogene Proteins
Chronic Hepatitis B
Hepatitis B virus
16 Citations (Scopus)

Identification of novel tumor markers for oral squamous cell carcinoma using glycoproteomic analysis

Chen, Y. T., Chong, Y. M., Cheng, C. W., Ho, C. L., Tsai, H. W., Kasten, F. H., Chen, Y. L. & Chang, C. F., 2013 Jan 1, In : Clinica Chimica Acta. 420, p. 45-53 9 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Polysaccharides
Squamous Cell Carcinoma
Keratinocytes
Fucosyltransferases
33 Citations (Scopus)

Lin28B is an oncofetal circulating cancer stem cell-like marker associated with recurrence of hepatocellular carcinoma

Cheng, S. W., Tsai, H. W., Lin, Y. J., Cheng, P. N., Chang, Y. C., Yen, C. J., Huang, H. P., Chuang, Y. P., Chang, T. T., Lee, C. T., Chao, A., Chou, C. Y., Chan, S. H., Chow, N. H. & Ho, C. L., 2013 Nov 14, In : PloS one. 8, 11, e80053.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
hepatoma
Stem cells
stem cells
Tumors
148 Citations (Scopus)

MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway

Hsieh, I. S., Chang, K. C., Tsai, Y. T., Ke, J. Y., Lu, P. J., Lee, K. H., Yeh, S. D., Hong, T. M. & Chen, Y. L., 2013 Mar 1, In : Carcinogenesis. 34, 3, p. 530-538 9 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
MicroRNAs
Prostatic Neoplasms
Stem Cells
Down-Regulation
1 Citation (Scopus)

Partial nephrectomy without renal ischemia using an electromagnetic thermal surgery system in a porcine model

Ou, C. H., Yang, W. H., Tsai, H. W., Lee, T. J., Chen, S. Y., Huang, S. C., Chang, Y. Y., Lee, G. B. & Lin, X. Z., 2013 May 1, In : Urology. 81, 5, p. 1101-1107 7 p.

Research output: Contribution to journalArticle

Electromagnetic Phenomena
Nephrectomy
Swine
Ischemia
Hot Temperature
13 Citations (Scopus)
Pneumocystis carinii
Pneumocystis Pneumonia
Taiwan
Systemic Lupus Erythematosus
Pneumocystis
8 Citations (Scopus)

Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphoma

Chang, K. C., Chang, W. C., Chang, Y., Hung, L. Y., Lai, C. H., Yeh, Y. M., Chou, Y. W. & Chen, C. H., 2013 Nov 6, In : PloS one. 8, 11, e79863.

Research output: Contribution to journalArticle

ran GTP-Binding Protein
GTPase-activating proteins
GTPase-Activating Proteins
Lymphoma, Large B-Cell, Diffuse
lymphoma