Research Output

1998

Lamotrigine inhibits depolarization-evoked Ca++ influx in dissociated amygdala neurons

Wang, S. J., Tsai, J. J. & Gean, P-W., 1998 Aug 1, In : Synapse. 29, 4, p. 355-362 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Potentiation of N-methyl-D-aspartate currents by isoproterenol in the acutely dissociated rat amygdalar neurons

Huang, C. C., Lin, C. H. & Gean, P. W., 1998 Aug 28, In : Neuroscience Letters. 253, 1, p. 9-12 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Selective enhancement of P-type calcium currents by isoproterenol in the rat amygdala

Huang, C. C., Wang, S. J. & Gean, P. W., 1998 Mar 15, In : Journal of Neuroscience. 18, 6, p. 2276-2282 7 p.

Research output: Contribution to journalArticle

Open Access
39 Citations (Scopus)
94 Citations (Scopus)

Synthesis of 1-(2-Carboxyethylbenzyl)-2-benzenesulfonamidobicyclo[2.2.1]heptane: A Novel Potent Thromboxane Antagonist

Kan, W. M., Chern, C. Y. & Su, S. F., 1998 Jan 1, In : Journal of the Chinese Chemical Society. 45, 6, p. 711-712 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Vanadate-dependent FAK activation is accomplished by the sustained FAK Tyr-576/577 phosphorylation

Maa, M. C. & Leu, T. H., 1998 Oct 9, In : Biochemical and Biophysical Research Communications. 251, 1, p. 344-349 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
1999

Asymmetric cyclization and microbial transformation for steroid synthesis+

Kan, W-M., 1999 Feb, In : Chinese Pharmaceutical Journal. 51, 1, p. 1-14 14 p.

Research output: Contribution to journalReview article

Cross-modulation of synaptic plasticity by β-adrenergic and 5-HT(1A) receptors in the rat basolateral amygdala

Wang, S. J., Cheng, L. L. & Gean, P. W., 1999 Jan 15, In : Journal of Neuroscience. 19, 2, p. 570-577 8 p.

Research output: Contribution to journalArticle

Open Access
37 Citations (Scopus)

C-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

Biscardi, J. S., Maa, M. C., Tice, D. A., Cox, M. E., Leu, T. H. & Parsons, S. J., 1999 Mar 19, In : Journal of Biological Chemistry. 274, 12, p. 8335-8343 9 p.

Research output: Contribution to journalArticle

532 Citations (Scopus)

Enhancement of tyrosyl phosphorylation and protein expression of eps8 by v-Src

Maa, M. C., Lai, J. R., Lin, R. W. & Leu, T. H., 1999 Jul 8, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1450, 3, p. 341-351 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Induction of 12-lipoxygenase expression by transforming growth factor-α in human epidermoid carcinoma A431 cells

Chen, L. C., Chen, B. K., Liu, Y. W. & Chang, W. C., 1999 Jul 16, In : FEBS Letters. 455, 1-2, p. 105-110 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Influence of polymorphism at p53, CYP1A1 and GSTM1 loci on p53 mutation and association of p53 mutation with prognosis in lung cancer

Wang, Y. C., Chen, C. Y., Wang, H. J., Chen, S. K., Chang, Y. Y. & Lin, P., 1999 Jul, In : Chinese Medical Journal (Taipei). 62, 7, p. 395-403 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Involvement of mitogen-activated protein kinase in hippocampal long-term potentiation

Wu, S. P., Lu, K. T., Chang, W. C. & Gean, P. W., 1999 Jan 1, In : Journal of biomedical science. 6, 6, p. 409-417 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Long-term depression of excitatory synaptic transmission the rat amygdala

Wang, S. J. & Gean, P. W., 1999 Dec 15, In : Journal of Neuroscience. 19, 24, p. 10656-10663 8 p.

Research output: Contribution to journalArticle

Open Access
56 Citations (Scopus)

Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampus

Lu, K. T. & Gean, P. W., 1999 Jan 1, In : Neuroscience. 88, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
32 Citations (Scopus)

Overexpression of c-Fos enhances the transcription of human arachidonate 12-lipoxygenase in A431 cells

Chen, B. K. & Chang, W. C., 1999 Aug 11, In : Biochemical and Biophysical Research Communications. 261, 3, p. 848-852 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

p53 Codon 72 polymorphism in Taiwanese lung cancer patients: Association with lung cancer susceptibility and prognosis

Wang, Y-C., Chen, C. Y., Chen, S. K., Chang, Y. Y. & Lin, P., 1999 Jan 28, In : Clinical Cancer Research. 5, 1, p. 129-134 6 p.

Research output: Contribution to journalArticle

164 Citations (Scopus)

Prognostic significance of p53 codon 72 polymorphism in lung carcinomas

Wang, Y. C., Lee, H. S., Chen, S. K., Chang, Y. Y. & Chen, C. Y., 1999 Feb 1, In : European Journal of Cancer. 35, 2, p. 226-230 5 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Promotion of forskolin-induced long-term potentiation of synaptic transmission by caffeine in area CA1 of the rat hippocampus

Lu, K. T., Wu, S. P. & Gean, P-W., 1999 Dec 31, In : Chinese Journal of Physiology. 42, 4, p. 249-253 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2000

Activation of group II metabotropic glutamate receptors induces long-term depression of synaptic transmission in the rat amygdala

Wang, H. C., Lin, S. J., Luo, M. Z. & Gean, P. W., 2000 Dec 15, In : Journal of Neuroscience. 20, 24, p. 9017-9024 8 p.

Research output: Contribution to journalArticle

Open Access
51 Citations (Scopus)

Correlation of genetic instability with mismatch repair protein expression and p53 mutations in non-small cell lung cancer

Chang, J. W., Chen, Y. C., Chen, C. Y., Chen, J. T., Chen, S. K. & Wang, Y-C., 2000 May 1, In : Clinical Cancer Research. 6, 5, p. 1639-1646 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells

Shen, M. R., Droogmans, G., Eggermont, J., Voets, T., Ellory, J. C. & Nilius, B., 2000 Dec 1, In : Journal of Physiology. 529, 2, p. 385-394 10 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus

Young, C., Gean, P. W., Chiou, L. C. & Shen, Y. Z., 2000 Jul 22, In : Synapse. 37, 2, p. 90-94 5 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Essential role of mitogen-activated protein kinase pathway and c-Jun induction in epidermal growth factor-induced gene expression of human 12- lipoxygenase

Chen, B. K., Kung, H. C., Tsai, T. Y. & Chang, W. C., 2000 Jan 1, In : Molecular Pharmacology. 57, 1, p. 153-161 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
62 Citations (Scopus)

Lack of evidence of association of p21(WAF1/CIP1) polymorphism with lung cancer susceptibility and prognosis in Taiwan

Shih, C. M., Lin, P. T., Wang, H. C., Huang, W. C. & Wang, Y. C., 2000 Jan, In : Japanese Journal of Cancer Research. 91, 1, p. 9-15 7 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Volume-sensitive KCl cotransport associated with human cervical carcinogenesis

Shen, M. R., Chou, C. Y. & Ellory, J. C., 2000 Jan 1, In : Pflugers Archiv European Journal of Physiology. 440, 5, p. 751-760 10 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
2001

A Role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala

Lin, C. H., Yeh, S. H., Lin, C. H., Lu, K. T., Leu, T. H., Chang, W. C. & Gean, P. W., 2001 Sep 13, In : Neuron. 31, 5, p. 841-851 11 p.

Research output: Contribution to journalArticle

297 Citations (Scopus)

Dissociation between synaptic depression and block of long-term depression induced by raising the temperature in rat hippocampal slices

Young, C., Luo, M. Z., Shen, Y. Z. & Gean, P-W., 2001 Mar 10, In : Synapse. 40, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Effect of hydroxyzine on the transport of etoposide in rat small intestine

Kan, W. M., Liu, Y. T., Hsiao, C. L., Shieh, C. Y., Kuo, J. H., Huang, J. D. & Su, S. F., 2001 Apr 17, In : Anti-Cancer Drugs. 12, 3, p. 267-273 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Human cervical cancer cells use Ca2+ signalling, protein tyrosine phosphorylation and MAP kinase in regulatory volume decrease

Shen, M. R., Chou, C. Y., Browning, J. A., Wilkins, R. J. & Clive Ellory, J., 2001 Dec 1, In : Journal of Physiology. 537, 2, p. 347-362 16 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Lamotrigine inhibition of glutamate release from isolated cerebrocortical nerve terminals (synaptosomes) by suppression of voltage-activated calcium channel activity

Wang, S. J., Sihra, T. S. & Gean, P. W., 2001 Jul 20, In : NeuroReport. 12, 10, p. 2255-2258 4 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Loss of p16 and/or pRb protein expression in NSCLC: An immunohistochemical and prognostic study

Chen, J. T., Chen, Y. C., Chen, C. Y. & Wang, Y. C., 2001 Feb 10, In : Lung Cancer. 31, 2-3, p. 163-170 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Modulation of voltage-dependent calcium currents by serotonin in acutely isolated rat amygdala neurons

Lin, C. H., Huang, Y. C., Tsai, J. J. & Gean, P. W., 2001 Sep 15, In : Synapse. 41, 4, p. 351-359 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Novel lead generation through hypothetical pharmacophore three-dimensional database searching: Discovery of isoflavonoids as nonsteroidal inhibitors of rat 5α-reductase

Chen, G. S., Chang, C. S., Kan, W-M., Chang, C. L., Wang, K. C. & Chern, J. W., 2001 Nov 8, In : Journal of Medicinal Chemistry. 44, 23, p. 3759-3763 5 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Overexpression of p97Eps8 leads to cellular transformatioan: Implication of pleckstrin homology domain in p97Eps8-mediated ERK activation

Maa, M. C., Hsieh, C. Y. & Leu, T. H., 2001 Jan 1, In : Oncogene. 20, 1, p. 106-112 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Selective enhancement of L-type calcium currents by corticotropin in acutely isolated rat amygdala neurons

Young, C., Huang, Y. C., Lin, C. H., Shen, Y. Z. & Gean, P. W., 2001 Jan 1, In : Molecular Pharmacology. 59, 3, p. 604-611 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
30 Citations (Scopus)

The KCI cotransporter isoform KCC3 can play an important role in cell growth regulation

Shen, M. R., Chou, C. Y., Hsu, K. F., Liu, H. S., Dunham, P. B., Holtzman, E. J. & Ellory, J. C., 2001 Dec 4, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 25, p. 14714-14719 6 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)
2002

Alterations of the p16INK4a gene in resected nonsmall cell lung tumors and exfoliated cells within sputum

Chen, J. T., Chen, Y. C., Wang, Y. C., Tseng, R. C., Chen, C. Y. & Wang, Y-C., 2002 Apr 10, In : International Journal of Cancer. 98, 5, p. 724-731 8 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Anion exchanger isoform 2 operates in parallel with Na+/H+ exchanger isoform 1 during regulatory volume decrease of human cervical cancer cells

Shen, M. R., Wilkins, R. J., Chou, C. Y. & Ellory, J. C., 2002 Feb 13, In : FEBS Letters. 512, 1-3, p. 52-58 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
27 Citations (Scopus)

A requirement of nuclear factor-κB activation in fear-potentiated startle

Yeh, S. H., Lin, C. H., Lee, C. F. & Gean, P. W., 2002 Nov 29, In : Journal of Biological Chemistry. 277, 48, p. 46720-46729 10 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Association of L-myc polymorphism with lung cancer susceptibility and prognosis in relation to age-selected controls and stratified cases

Shih, C. M., Kuo, Y. Y., Wang, Y. C., Jian, S. L., Hsu, Y. T., Wu, H. Y., Guo, M. W. & Wang, Y. C., 2002 Jan 1, In : Lung Cancer. 36, 2, p. 125-132 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Caspase activation of Mammalian Sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis

Huang, C. Y. F., Wu, Y. M., Hsu, C. Y., Lee, W. S., Lai, M. D., Lu, T. J., Huang, C. L., Leu, T. H., Shih, H. M., Fang, H. I., Robinson, D. R., Kungand, H. J. & Yuan, C. J., 2002 Sep 13, In : Journal of Biological Chemistry. 277, 37, p. 34367-34374 8 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Design and synthesis of 1,2,4-oxadiazole derivatives as non-steroidal 5α-reductase inhibitors

Chang, C. S., Kan, W. M., Chen, C. L., Wang, K. C. & Chern, J. W., 2002 Jan 1, In : Journal of the Chinese Chemical Society. 49, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Functional role of extracellular signal-regulated kinase activation and c-Jun induction in phorbol ester-induced promoter activation of human 12(S)-lipoxygenase gene

Chen, B-K., Tsai, T. Y., Huang, H-S., Chen, L. C., Chang, W. C., Tsai, S. B. & Chang, W. C., 2002 Apr 6, In : Journal of biomedical science. 9, 2, p. 156-165 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Gene regulation of human 12(S)-lipoxygenase

Chang, W. C. & Chen, B. K., 2002 Nov 1, In : International Congress Series. 1233, C, p. 329-335 7 p.

Research output: Contribution to journalArticle