Research Output

CBL is frequently altered in lung cancers: Its relationship to mutations in met and EGFR tyrosine kinases

Tan, Y. H. C., Krishnaswamy, S., Nandi, S., Kanteti, R., Vora, S., Onel, K., Hasina, R., Lo, F. Y., El-Hashani, E., Cervantes, G., Robinson, M., Kales, S. C., Lipkowitz, S., Karrison, T., Sattler, M., Vokes, E. E., Wang, Y. C. & Salgia, R., 2010 Jan 29, In : PloS one. 5, 1, e8972.

Research output: Contribution to journalArticle

81 Citations (Scopus)
36 Citations (Scopus)

Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells

Hsieh, C. C., Kuo, Y. H., Kuo, C. C., Chen, L. T., Cheung, C. H. A., Chao, T. Y., Lin, C. H., Pan, W. Y., Chang, C. Y., Chien, S. C., Chen, T. W., Lung, C. C. & Chang, J. Y., 2010 May 1, In : Biochemical Pharmacology. 79, 9, p. 1261-1271 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma

Hsu, H. S., Chen, T. P., Hung, C. H., Wen, C. K., Lin, R. K., Lee, H. C. & Wang, Y-C., 2007 Nov 1, In : Cancer. 110, 9, p. 2019-2026 8 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)

Characterization of the epileptiform activity induced by magnesium-free solution in rat amygdala slices: An intracellular study

Gean, P-W. & Shinnick-Gallagher, P., 1988 Jan 1, In : Experimental Neurology. 101, 2, p. 248-255 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Chloride-dependent inhibitory postsynaptic potentials recorded in amygdalar slices of rat

Gean, P. W. & Hung, C. R., 1992 Jan 1, In : Asia Pacific Journal of Pharmacology. 7, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

Chronic cannabinoid administration in vivo compromises extinction of fear memory

Lin, H. C., Mao, S. C., Chen, P-S. & Gean, P-W., 2008 Dec 1, In : Learning and Memory. 15, 12, p. 876-884 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
3 Citations (Scopus)

CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression

Liao, S. Y., Chiang, C-W., Hsu, C. H., Chen, Y. T., Jen, J., Juan, H. F., Lai, W-W. & Wang, Y-C., 2017 Oct 12, In : Oncogene. 36, 41, p. 5722-5733 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Clinical aspects for survivin: A crucial molecule for targeting drug-resistant cancers

Singh, N., Krishnakumar, S., Kanwar, R. K., Cheung, C. H. A. & Kanwar, J. R., 2015 May 1, In : Drug Discovery Today. 20, 5, p. 578-587 10 p.

Research output: Contribution to journalReview article

51 Citations (Scopus)
39 Citations (Scopus)

Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli

Tsai, S. L., Chang, Y. C., Sarvagalla, S., Wang, S., Coumar, M. S. & Cheung, C. H. A., 2019 Aug, In : Protein Expression and Purification. 160, p. 73-83 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Coagulation factor VII and malignant progression of hepatocellular carcinoma

Chen, K. D., Huang, K. T., Tsai, M. C., Wu, C. H., Kuo, I. Y., Chen, L. Y., Hu, T. H., Chen, C. L. & Lin, C. C., 2016, In : Cell Death and Disease. 7, 2, e2110.

Research output: Contribution to journalComment/debate

Open Access
4 Citations (Scopus)
10 Citations (Scopus)
2 Citations (Scopus)
21 Citations (Scopus)

Comparison of the rate of excision of major UV photoproducts in the strands of the human HPRT gene of normal and xeroderma pigmentosum variant cells

Tung, B. S., McGregor, W. G., Wang, Y. C., Maher, V. M. & McCormick, J. J., 1996 Jan 2, In : Mutation Research - DNA Repair. 362, 1, p. 65-74 10 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model

Roy, K., Kanwar, R. K., Krishnakumar, S., Cheung, C. H. A. & Kanwar, J. R., 2015 Feb 2, In : International journal of nanomedicine. 10, p. 1019-1043 25 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
Open Access

Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy

Hsu, K. F., Wu, C. L., Huang, S. C., Hsieh, J. L., Huang, Y. S., Chen, Y. F., Shen, M. R., Chung, W. J., Chou, C. Y. & Shiau, A. L., 2008 Aug 18, In : Cancer Gene Therapy. 15, 8, p. 526-534 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Correction: Inhibition of spontaneous recovery of fear by mGlur5 after prolonged extinction training (PLoS ONE (2013) 8, 3 (e59580) DOI: 10.1371/journal.pone.0059580)

Mao, S. C., Chang, C. H., Wu, C. C., Orejanera, M. J., Manzoni, O. J. & Gean, P. W., 2013 Jun 27, In : PloS one. 8, 6

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Correction: A cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy

Cheung, C. H. A., Sun, X., Kanwar, J. R., Bai, J. Z., Cheng, L. & Krissansen, G. W., 2010 Oct 28, In : Cancer Cell International. 10, 43.

Research output: Contribution to journalComment/debate

10 Citations (Scopus)

Correlation of genetic instability with mismatch repair protein expression and p53 mutations in non-small cell lung cancer

Chang, J. W., Chen, Y. C., Chen, C. Y., Chen, J. T., Chen, S. K. & Wang, Y-C., 2000 May 1, In : Clinical Cancer Research. 6, 5, p. 1639-1646 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Cross-modulation of synaptic plasticity by β-adrenergic and 5-HT(1A) receptors in the rat basolateral amygdala

Wang, S. J., Cheng, L. L. & Gean, P. W., 1999 Jan 15, In : Journal of Neuroscience. 19, 2, p. 570-577 8 p.

Research output: Contribution to journalArticle

Open Access
37 Citations (Scopus)

C-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

Biscardi, J. S., Maa, M. C., Tice, D. A., Cox, M. E., Leu, T. H. & Parsons, S. J., 1999 Mar 19, In : Journal of Biological Chemistry. 274, 12, p. 8335-8343 9 p.

Research output: Contribution to journalArticle

532 Citations (Scopus)
10 Citations (Scopus)

Cyclic AMP (cAMP) confers drug resistance against DNA damaging agents via PKAIA in CML cells

Xiao, L. Y. & Kan, W. M., 2017 Jan 1, In : European Journal of Pharmacology. 794, p. 201-208 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cytotoxicity and proteomics analyses of OSU03013 in lung cancer

Tan, Y. H., Lee, K. H., Lin, T., Sun, Y. C., Hsieh-Li, H. M., Juan, H. F. & Wang, Y. C., 2008 Mar 15, In : Clinical Cancer Research. 14, 6, p. 1823-1830 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
19 Citations (Scopus)

Damage formation and repair efficiency in the p53 gene of cell lines and blood lymphocytes assayed by multiplex long quantitative polymerase chain reaction

Wang, Y. C., Lee, P. J., Shih, C. M., Chen, H. Y., Lee, C. C., Chang, Y. Y., Hsu, Y. T., Liang, Y. J., Wang, L. Y., Han, W. H. & Wang, Y. C., 2003 Aug 15, In : Analytical Biochemistry. 319, 2, p. 206-215 10 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Deficiency of electroneutral K+-Cl- cotransporter 3 causes a disruption in impulse propagation along peripheral nerves

Sun, Y-T., Lin, T-S., Tzeng, S-F., Delpire, E. & Shen, M-R., 2010 Oct 1, In : GLIA. 58, 13, p. 1544-1552 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Deficiency of intrarenal angiotensin II type 2 receptor impairs paired homeo box-2 and N-myc expression during nephrogenesis

Chen, Y-W., Tran, S., Chenier, I., Chan, J. S. D., Ingelfinger, J. R., Inagami, T. & Zhang, S. L., 2008 Jul 9, In : Pediatric Nephrology. 23, 10, p. 1769-1777 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Delivery of a survivin Promoter-Driven antisense Survivin-Expressing plasmid DNA as a cancer therapeutic: A proof-of-concept study

Lin, K. Y., Cheng, S. M., Tsai, S. L., Tsai, J. Y., Lin, C. H. & Cheung, C. H. A., 2016 May 3, In : OncoTargets and Therapy. 9, p. 2601-2613 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Deregulation of SLIT2-mediated Cdc42 activity is associated with esophageal cancer metastasis and poor prognosis

Tseng, R. C., Chang, J. M., Chen, J. H., Huang, W. R., Tang, Y. A., Kuo, I. Y., Yan, J. J., Lai, W. W. & Wang, Y. C., 2015 Jan 1, In : Journal of Thoracic Oncology. 10, 1, p. 189-198 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Design and synthesis of 1,2,4-oxadiazole derivatives as non-steroidal 5α-reductase inhibitors

Chang, C. S., Kan, W. M., Chen, C. L., Wang, K. C. & Chern, J. W., 2002 Jan 1, In : Journal of the Chinese Chemical Society. 49, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Design and synthesis of 3-aryl-5-alicylic-[1,2,4]-oxadiazoles as novel platelet aggregation inhibitors

Chern, C. Y., Chen, S. J. & Kan, W. M., 2005 Jan 1, In : Journal of the Chinese Chemical Society. 52, 2, p. 331-338 8 p.

Research output: Contribution to journalArticle

Differential Ca2+ mobilization and mast cell degranulation by FcεRI- and GPCR-mediated signaling

Chen, Y. C., Chang, Y. C., Chang, H. A., Lin, Y. S., Tsao, C. W., Shen, M. R. & Chiu, W. T., 2017 Nov, In : Cell Calcium. 67, p. 31-39 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
1 Citation (Scopus)

Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells

Shen, M. R., Droogmans, G., Eggermont, J., Voets, T., Ellory, J. C. & Nilius, B., 2000 Dec 1, In : Journal of Physiology. 529, 2, p. 385-394 10 p.

Research output: Contribution to journalArticle

148 Citations (Scopus)

Differential osmosensing signalling pathways and G-protein involvement in human cervical cells with different tumour potential

Shen, M. R., Chou, C. Y., Wu, M. L. & Huang, K. E., 1998 Feb 1, In : Cellular Signalling. 10, 2, p. 113-120 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Direct inhibitory effect of curcumin on Src and focal adhesion kinase activity

Leu, T. H., Su, S. L., Chuang, Y. C. & Maa, M. C., 2003 Dec 15, In : Biochemical Pharmacology. 66, 12, p. 2323-2331 9 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Direct interaction of C/EBPδ and Sp1 at the GC-enriched promoter region synergizes the IL-10 gene transcription in mouse macrophage

Chiang, B. T., Liu, Y. W., Chen, B. K., Wang, J. M. & Chang, W. C., 2006 Sep, In : Journal of biomedical science. 13, 5, p. 621-635 15 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and: In vitro testing for the anti-cancer drug target-survivin

Sarvagalla, S., Cheung, C. H. A., Tsai, J. Y., Hsieh, H. P. & Coumar, M. S., 2016 Jan 1, In : RSC Advances. 6, 38, p. 31947-31959 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Dissociation between synaptic depression and block of long-term depression induced by raising the temperature in rat hippocampal slices

Young, C., Luo, M. Z., Shen, Y. Z. & Gean, P-W., 2001 Mar 10, In : Synapse. 40, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Distinct epigenetic domains separated by a CTCF bound insulator between the tandem genes, BLU and RASSF1A

Chang, J. W., Hsu, H. S., Ni, H. J., Chuang, C. T., Hsiung, C. H., Huang, T. H. & Wang, Y. C., 2010, In : PloS one. 5, 9, p. 1-13 13 p., e12847.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients

Tseng, R. C., Lee, C. C., Hsu, H. S., Tzao, C. & Wang, Y. C., 2009 Aug, In : Neoplasia. 11, 8, p. 763-770 8 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Distinctive roles of different β-amyloid 42 aggregates in modulation of synaptic functions

Chiang, H. C., Iijima, K., Hakker, I. & Zhong, Y., 2009 Jun, In : FASEB Journal. 23, 6, p. 1969-1977 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)