Research Output

hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing

Lee, C. F., Ou, D. S. C., Lee, S. B., Chang, L. H., Lin, R. K., Li, Y. S., Upadhyay, A. K., Cheng, X., Wang, Y. C., Hsu, H. S., Hsiao, M., Wu, C. W. & Juan, L. J., 2010 Aug 2, In : Journal of Clinical Investigation. 120, 8, p. 2920-2930 11 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Human cervical cancer cells use Ca2+ signalling, protein tyrosine phosphorylation and MAP kinase in regulatory volume decrease

Shen, M. R., Chou, C. Y., Browning, J. A., Wilkins, R. J. & Clive Ellory, J., 2001 Dec 1, In : Journal of Physiology. 537, 2, p. 347-362 16 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer

Kuo, Y. Z., Fang, W. Y., Huang, C. C., Tsai, S. T., Wang, Y. C., Yang, C. L. & Wu, L. W., 2017 Jan 1, In : Oncotarget. 8, 9, p. 15563-15583 21 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Hypoxia-inducible factor-1α protects cultured cortical neurons from lipopolysaccharide-induced cell death via regulation of NR1 expression

Yeh, S. H., Hung, J. J., Gean, P. W. & Chang, W., 2008 Dec 24, In : Journal of Neuroscience. 28, 52, p. 14259-14270 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60(src) substrate

Flynn, D. C., Leu, T. H., Reynolds, A. B. & Parsons, J. T., 1993, In : Molecular and Cellular Biology. 13, 12, p. 7892-7900 9 p.

Research output: Contribution to journalArticle

104 Citations (Scopus)

IDENTIFICATION OF ADENOSINE RECEPTORS IN HUMAN SPERMATOZOA

Shen, MR. R., Linden, J., Chen, SS. S. & Wu, SN. N., 1993 Aug, In : Clinical and Experimental Pharmacology and Physiology. 20, 7-8, p. 527-534 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Identification of calcineurin as a key signal in the extinction of fear memory

Lin, C. H., Yeh, S. H., Leu, T. H., Chang, W. C., Wang, S. T. & Gean, P. W., 2003 Mar 1, In : Journal of Neuroscience. 23, 5, p. 1574-1579 6 p.

Research output: Contribution to journalArticle

Open Access
136 Citations (Scopus)

Identifying the factors and signal pathways necessary for anchorage-independent growth of Ha-ras oncogene-transformed NIH/3T3 cells

Chang, T. Y., Tsai, W. J., Chou, C. K., Chow, N. H., Leu, T. H. & Liu, H. S., 2003 Jul 25, In : Life Sciences. 73, 10, p. 1265-1274 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

IGF-1 upregulates electroneutral K-Cl cotransporter KCC3 and KCC4 which are differentially required for breast cancer cell proliferation and invasiveness

Hsu, Y. M., Chou, C-Y., Chen, H. H. W., Lee, W. Y., Chen, Y. F., Lin, P. W., Alper, S. L., Ellory, J. C. & Shen, M-R., 2007 Mar 1, In : Journal of Cellular Physiology. 210, 3, p. 626-636 11 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
16 Citations (Scopus)
2 Citations (Scopus)

Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples

Wang, Y. C., Lu, Y. P., Tseng, R. C., Lin, R. K., Chang, J. W., Chen, J. T., Shih, C. M. & Chen, C. Y., 2003 Mar, In : Journal of Clinical Investigation. 111, 6, p. 887-895 9 p.

Research output: Contribution to journalArticle

117 Citations (Scopus)
27 Citations (Scopus)

Induction of 12-lipoxygenase expression by phorbol 12-myristate 13-acetate in human epidermoid carcinoma A431 cells

Liaw, Y. W., Liu, Y. W., Chen, B. K. & Chang, W. C., 1998 Jan 5, In : Biochimica et Biophysica Acta - Lipids and Lipid Metabolism. 1389, 1, p. 23-33 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Induction of 12-lipoxygenase expression by transforming growth factor-α in human epidermoid carcinoma A431 cells

Chen, L. C., Chen, B. K., Liu, Y. W. & Chang, W. C., 1999 Jul 16, In : FEBS Letters. 455, 1-2, p. 105-110 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Influence of polymorphism at p53, CYP1A1 and GSTM1 loci on p53 mutation and association of p53 mutation with prognosis in lung cancer

Wang, Y. C., Chen, C. Y., Wang, H. J., Chen, S. K., Chang, Y. Y. & Lin, P., 1999 Jul, In : Chinese Medical Journal (Taipei). 62, 7, p. 395-403 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST

Lu, T. J., Lai, W. Y., Huang, C. Y. F., Hsieh, W. J., Yu, J. S., Hsieh, Y. J., Chang, W. T., Leu, T. H., Chang, W. C., Chuang, W. J., Tang, M. J., Chen, T. Y., Lu, T. L. & Lai, M. D., 2006 Dec 15, In : Journal of Biological Chemistry. 281, 50, p. 38405-38417 13 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Inhibition of glioma growth by minocycline is mediated through endoplasmic reticulum stress-induced apoptosis and autophagic cell death

Liu, W. T., Huang, C. Y., Lu, I. C. & Gean, P. W., 2013 Sep 1, In : Neuro-Oncology. 15, 9, p. 1127-1141 15 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Inhibition of HDAC3- and HDAC6-promoted survivin expression plays an important role in SAHA-induced autophagy and viability reduction in breast cancer cells

Lee, J. Y. C., Kuo, C. W., Tsai, S. L., Cheng, S. M., Chen, S. H., Chan, H. H., Lin, C. H., Lin, K. Y., Li, C. F., Kanwar, J. R., Leung, E. Y., Cheung, C. C. H., Huang, W. J., Wang, Y. C. & Cheung, C. H. A., 2016 Mar 31, In : Frontiers in Pharmacology. 7, MAR, 81.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Inhibition of initiation of simian virus 40 DNA replication during acute response of cells irradiated by ultraviolet light

Wang, Y. C. & Hsu, M. T., 1996, In : Nucleic acids research. 24, 16, p. 3149-3157 9 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Inhibition of N-type calcium currents by lamotrigine in rat amygdalar neurones

Wang, S. J., Huang, C. C., Hsu, K-S., Tsai, J. J. & Gean, P-W., 1996 Jan 1, In : NeuroReport. 7, 18, p. 3037-3040 4 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Inhibition of Spontaneous Recovery of Fear by mGluR5 after Prolonged Extinction Training

Mao, S. C., Chang, C. H., Wu, C. C., Orejanera, M. J., Manzoni, O. J. & Gean, P. W., 2013 Mar 21, In : PloS one. 8, 3, e59580.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Inhibition of synaptic transmission and epileptiform activity in central neurones by fluspirilene

Wang, S. J., Lu, K. T. & Gean, P. W., 1997, In : British Journal of Pharmacology. 120, 6, p. 1114-1118 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
71 Citations (Scopus)

Insulin-like growth factor 1 stimulates KCl cotransport, which is necessary for invasion and proliferation of cervical cancer and ovarian cancer cells

Shen, M. R., Lin, A. C., Hsu, Y. M., Chang, T. J., Tang, M. J., Alper, S. L., Ellory, J. C. & Chou, C. Y., 2004 Sep 17, In : Journal of Biological Chemistry. 279, 38, p. 40017-40025 9 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)
11 Citations (Scopus)

Integrative genomic analysis for the functional roles of ITPKC in bone mineral density

Lu, H. F., Wong, H. S. C., Chen, B. K., Liao, H. T., Hsu, Y. W., Ikegawa, S., Cho, E. C., Hung, K. S. & Chang, W. C., 2018 Nov 30, In : Bioscience Reports. 38, 6, BSR20181481.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Investigations of survivin: The past, present and future

Cheung, C. H. A., Cheng, L. T., Chang, K. Y., Chen, H. H. & Chang, J. Y., 2011 Jan 1, In : Frontiers in Bioscience. 16, 3, p. 952-961 10 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Investigations on the mechanism of tetrahydro-9-aminoacridine-induced presynaptic inhibition in the rat amygdala

Wang, S. J., Huang, C. C. & Gean, P. W., 1996 Jan 1, In : Neuroscience. 70, 2, p. 409-415 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Involvement of a calcineurin cascade in amygdala depotentiation and quenching of fear memory

Lin, C. H., Lee, C. C. & Gean, P-W., 2003 Jan 1, In : Molecular Pharmacology. 63, 1, p. 44-52 9 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

Involvement of aryl hydrocarbon receptor nuclear translocato in EGF-induced c-Jun/Sp1-mediated gene expression

Huang, W. C., Chen, S. T., Chang, W. C., Chang, K. Y., Chang, W. C. & Chen, B-K., 2010 Oct 1, In : Cellular and Molecular Life Sciences. 67, 20, p. 3523-3533 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Involvement of extracellular signal regulated kinases in traumatic brain injury-induced depression in rodents

Kuo, J. R., Cheng, Y. H., Chen, Y. S., Chio, C. C. & Gean, P. W., 2013 Jul 15, In : Journal of Neurotrauma. 30, 14, p. 1223-1231 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Involvement of intracellular calcium mobilization in IL-8 activation in human retinal pigment epithelial cells

Yang, I. H., Wong, J. H., Chang, C. M., Chen, B. K., Tsai, Y. T., Chen, W. C., Wang, E. T., Hsu, W. L. & Chang, W. C., 2015, In : Investigative Ophthalmology and Visual Science. 56, 2, p. 761-769 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Involvement of L-type Ca2+ Channel and Toll-Like Receptor-4 in Nickel-Induced Interleukin-8 Gene Expression

Lin, C. H., Chung, C. A., Wong, J. H., Chen, B-K., Chiu, S. J., Klahan, S., Lee, Y. C. & Chang, W. C., 2016 Jan 1, In : Environmental Toxicology. 31, 1, p. 5-12 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
3 Citations (Scopus)

Involvement of mitogen-activated protein kinase in hippocampal long-term potentiation

Wu, S. P., Lu, K. T., Chang, W. C. & Gean, P. W., 1999 Jan 1, In : Journal of biomedical science. 6, 6, p. 409-417 9 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
31 Citations (Scopus)

Involvement of protein phosphatases in the destabilization of methamphetamine-Associated contextual memory

Yu, Y. J., Huang, C. H., Chang, C. H. & Gean, P. W., 2016 Sep, In : Learning and Memory. 23, 9, p. 486-493 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Involvement of STIM1 and Orai1 in EGF-mediated cell growth in retinal pigment epithelial cells

Yang, I. H., Tsai, Y. T., Chiu, S. J., Liu, L. T., Lee, H. H., Hou, M. F., Hsu, W. L., Chen, B. K. & Chang, W. C., 2013 Jun 27, In : Journal of biomedical science. 20, 1, 41.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells

Wang, J. Y., Chen, B. K., Wang, Y. S., Tsai, Y. T., Chen, W. C., Chang, W. C., Hou, M. F., Wu, Y. C. & Chang, W. C., 2012 Jan 1, In : Cellular Signalling. 24, 1, p. 162-169 8 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)
Open Access
91 Citations (Scopus)

K+-Cl- cotransport mediates the bactericidal activity of neutrophils by regulating NADPH oxidase activation

Sun, Y. T., Shieh, C. C., Delpire, E. & Shen, M. R., 2012 Jul 1, In : Journal of Physiology. 590, 14, p. 3231-3243 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2 Citations (Scopus)

KCl cotransporter-3 down-regulates E-cadherin/β-catenin complex to promote epithelial-mesenchymal transition

Hsu, Y. M., Chen, Y. F., Chou, C. Y., Tang, M. J., Chen, J. H., Wilkins, R. J., Clive Ellory, J. & Shen, M. R., 2007 Nov 15, In : Cancer Research. 67, 22, p. 11064-11073 10 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

KCl cotransport is an important modulator of human cervical cancer growth and invasion

Shen, M. R., Chou, C. Y., Hsu, K. F., Hsu, Y. M., Chiu, W. T., Tang, M. J., Alper, S. L. & Ellory, J. C., 2003 Oct 10, In : Journal of Biological Chemistry. 278, 41, p. 39941-39950 10 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Ketamine suppresses synchronized discharges in the disinhibited amygdala slice

Gean, P-W. & Fang-Chia, C., 1991 Jan 1, In : Brain Research Bulletin. 26, 6, p. 923-927 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)