Research Output

2017

Oleate-induced PTX3 promotes head and neck squamous cell carcinoma metastasis through the up-regulation of vimentin

Chan, S. H., Tsai, J. P., Shen, C. J., Liao, Y. H. & Chen, B. K., 2017, In : Oncotarget. 8, 25, p. 41364-41378 15 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Oleic acid-induced ANGPTL4 enhances head and neck squamous cell carcinoma anoikis resistance and metastasis via up-regulation of fibronectin

Shen, C. J., Chan, S-H., Lee, C-T., Huang, W. C., Tsai, J. P. & Chen, B-K., 2017 Feb 1, In : Cancer Letters. 386, p. 110-122 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Oncogenic MCT-1 activation promotes YY1-EGFR-MnSOD signaling and tumor progression

Tseng, H., Chen, Y., Jen, J., Shen, P., Chen, L., Lin, T., Wang, Y-C. & Hsu, H., 2017 Apr 1, In : Oncogenesis. 6, 4, p. e313-e313

Research output: Contribution to journalArticle

12 Citations (Scopus)

p53 modulates the effect of ribosomal protein S6 kinase1 (S6K1) on cisplatin toxicity in chronic myeloid leukemia cells

Xiao, L. Y. & Kan, W-M., 2017 May 1, In : Pharmacological Research. 119, p. 443-462 20 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Phosphorylation of Rab37 by protein kinase C alpha inhibits the exocytosis function and metastasis suppression activity of Rab37

Tzeng, H. T., Li, T. H., Tang, Y. A., Tsai, C. H., Lu, P. J. F., Lai, W. W., Chiang, C. W. & Wang, Y. C., 2017, In : Oncotarget. 8, 65, p. 108556-108570 15 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Poly ADP-ribose polymerase inhibition suppresses cisplatin toxicity in chronic myeloid leukemia cells

Xiao, L. Y. & Kan, W. M., 2017 Jan 1, In : Anti-Cancer Drugs. 28, 3, p. 316-321 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Prediction for Intravenous Immunoglobulin Resistance by Using Weighted Genetic Risk Score Identified from Genome-Wide Association Study in Kawasaki Disease

Kuo, H. C., Wong, H. S. C., Chang, W. P., Chen, B. K., Wu, M. S., Yang, K. D., Hsieh, K. S., Hsu, Y. W., Liu, S. F., Liu, X. & Chang, W. C., 2017 Oct 1, In : Circulation: Cardiovascular Genetics. 10, 5, e001625.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Selective serotonin reuptake inhibitor, fluoxetine, impairs E-cadherin-mediated cell adhesion and alters calcium homeostasis in pancreatic beta cells

Chang, H. Y., Chen, S. L., Shen, M. R., Kung, M. L., Chuang, L. M. & Chen, Y. W., 2017 Dec 1, In : Scientific reports. 7, 1, 3515.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Silver decorated copper oxide (Ag@CuO) nanocomposite enhances ROS-mediated bacterial architecture collapse

Kung, M., Tai, M., Lin, P., Wu, D., Wu, W., Yeh, B., Hung, H., Kuo, C., Chen, Y., Hsieh, S. & Hsieh, S., 2017 Jul 1, In : Colloids and Surfaces B: Biointerfaces. 155, p. 399-407

Research output: Contribution to journalArticle

STIM1-dependent Ca2+ signaling regulates podosome formation to facilitate cancer cell invasion

Chen, Y-W., Chen, Y. F., Chiu, W. T., Chen, H. C. & Shen, M. R., 2017 Dec 1, In : Scientific reports. 7, 1, 11523.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells

Chang, C. H., Liu, W. T., Hung, H. C., Gean, C. Y., Tsai, H. M., Su, C. L. & Gean, P. W., 2017 Dec 29, In : BMC cancer. 17, 1, 905.

Research output: Contribution to journalArticle

8 Citations (Scopus)

TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1

Huang, P. H., Lu, P. J., Ding, L. Y., Chu, P. C., Hsu, W. Y., Chen, C. S., Tsao, C. C., Chen, B. H., Lee, C. T., Shan, Y. S. & Chen, C. S., 2017 Apr 20, In : Oncogene. 36, 16, p. 2202-2214 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
7 Citations (Scopus)

Topical ophthalmic formulation of trichostatin A and SurR9-C84A for quick recovery post-alkali burn of corneal haze

Roy, K., Cheung, C. H. A., Kanwar, R. K., Sandhir, R. & Kanwar, J. R., 2017 May 5, In : Frontiers in Pharmacology. 8, MAY, 223.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

Wang, Y. T., Chen, J., Chang, C. W., Jen, J., Huang, T. Y., Chen, C. M., Shen, R., Liang, S. Y., Cheng, I. C., Yang, S. C., Lai, W. W., Cheng, K. H., Hsieh, T. S., Lai, M. Z., Cheng, H. C., Wang, Y. C. & Chen, R. H., 2017 Aug 1, In : Journal of Clinical Investigation. 127, 8, p. 2982-2997 16 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Vibrio vulnificus MARTX cytotoxin causes inactivation of phagocytosis-related signaling molecules in macrophages

Chen, C. L., Chien, S. C., Leu, T. H., Harn, H. I. C., Tang, M. J. & Hor, L. I., 2017 Aug 19, In : Journal of biomedical science. 24, 1, 58.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2018

Bcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis

Chiu, W. T., Chang, H. A., Lin, Y. H., Lin, Y. S., Chang, H. T., Lin, H. H., Huang, S. C., Tang, M. J. & Shen, M. R., 2018 Dec 1, In : Cell Death Discovery. 4, 1, 37.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Bcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis

Chiu, W., Chang, H., Lin, Y., Lin, Y., Chang, H., Lin, H., Huang, S., Tang, M. & Shen, M., 2018 Dec 1, In : Cell Death Discovery. 4, 1

Research output: Contribution to journalArticle

3 Citations (Scopus)

Dysfunction of different cellular degradation pathways contributes to specific β-amyloid42-induced pathologies

Ji, X. R., Cheng, K. C., Chen, Y. R., Lin, T. Y., Cheung, C. H. A., Wu, C. L. & Chiang, H. C., 2018 Mar, In : FASEB Journal. 32, 3, p. 1375-1387 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Functional engineered mesenchymal stem cells with fibronectin-gold composite coated catheters for vascular tissue regeneration

Chen, Y., Hsieh, S., Yang, Y., Hsu, S., Kung, M., Lin, P., Hsieh, H., Lin, C., Tang, C. & Hung, H., 2018 Apr 1, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 3, p. 699-711

Research output: Contribution to journalArticle

4 Citations (Scopus)

High-fat diet suppresses the astrocytic process arborization and downregulates the glial glutamate transporters in the hippocampus of mice

Tsai, S. F., Wu, H. T., Chen, P. C., Chen, Y. W., Yu, M., Wang, T. F., Wu, S. Y., Tzeng, S. F. & Kuo, Y. M., 2018 Dec 1, In : Brain Research. 1700, p. 66-77 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

High-fat diet suppresses the astrocytic process arborization and downregulates the glial glutamate transporters in the hippocampus of mice.

Tsai, SF., Wu, HT., Chen, PC. & Chen, Y-W., 2018 Jul 13, In : Brain Research. 18, p. 30401 3 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Integrative genomic analysis for the functional roles of ITPKC in bone mineral density

Lu, H. F., Wong, H. S. C., Chen, B. K., Liao, H. T., Hsu, Y. W., Ikegawa, S., Cho, E. C., Hung, K. S. & Chang, W. C., 2018 Nov 30, In : Bioscience Reports. 38, 6, BSR20181481.

Research output: Contribution to journalArticle

Mechanism underlying NMDA blockade-induced inhibition of aggression in post-weaning socially isolated mice

Chang, C. H., Su, C. L. & Gean, P. W., 2018 Dec, In : Neuropharmacology. 143, p. 95-105 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Medical Applications of Collagen and Hyaluronan in Regenerative Medicine

Huang, L. L. H., Chen, Y. H. A., Zhuo, Z. Y., Hsieh, Y. T., Yang, C. L., Chen, W. T., Lin, J. Y., Lin, Y. X., Jiang, J. T., Zhuang, C. H., Wang, Y. C., Nguyendac, H., Lin, K. W. & Liu, W. L., 2018 Jan 1, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 285-306 22 p. (Advances in Experimental Medicine and Biology; vol. 1077).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Mushroom body glycolysis is required for olfactory memory in Drosophila

Wu, C. L., Chang, C. C., Wu, J. K., Chiang, M. H., Yang, C. H. & Chiang, H. C., 2018 Apr, In : Neurobiology of Learning and Memory. 150, p. 13-19 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
5 Citations (Scopus)

Rab37 in lung cancer mediates exocytosis of soluble ST2 and thus skews macrophages toward tumor-suppressing phenotype

Tzeng, H. T., Su, C. C., Chang, C. P., Lai, W. W., Su, W. C. & Wang, Y-C., 2018 Oct 1, In : International Journal of Cancer. 143, 7, p. 1753-1763 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
4 Citations (Scopus)

VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function

Wang, Y., Tzeng, H., Tsai, C., Cheng, H., Lai, W., Liu, H. & Wang, Y., 2018 Nov 1, In : Cancer Letters. 437, p. 79-88

Research output: Contribution to journalArticle

3 Citations (Scopus)

Visualization of Membrane Pore in Live Cells Reveals a Dynamic-Pore Theory Governing Fusion and Endocytosis

Shin, W., Ge, L., Arpino, G., Villarreal, S. A., Hamid, E., Liu, H., Zhao, W. D., Wen, P. J., Chiang, H. C. & Wu, L. G., 2018 May 3, In : Cell. 173, 4, p. 934-945.e12

Research output: Contribution to journalArticle

47 Citations (Scopus)

XBP1 and PERK Have Distinct Roles in Aβ-Induced Pathology

Cheng, K. C. & Chiang, H. C., 2018 Sep 1, In : Molecular Neurobiology. 55, 9, p. 7523-7532 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

Aging-induced Akt activation involves in aging-related pathologies and Aβ-induced toxicity

Chen, Y. R., Li, Y. H., Hsieh, T. C., Wang, C. M., Cheng, K. C., Wang, L., Lin, T. Y., Cheung, C. H. A., Wu, C. L. & Chiang, H. C., 2019 Aug, In : Aging Cell. 18, 4, e12989.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

AKT-mediated phosphorylation enhances protein stability and transcription activity of ZNF322A to promote lung cancer progression

Liao, S. Y., Kuo, I. Y., Chen, Y. T., Liao, P. C., Liu, Y. F., Wu, H. Y., Lai, W. W. & Wang, Y. C., 2019 Oct 10, In : Oncogene. 38, 41, p. 6723-6736 14 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Association of gout and colorectal cancer in Taiwan: A nationwide population-based cohort study

Chuang, J. P., Lee, J. C., Leu, T. H., Hidajah, A. C., Chang, Y. H. & Li, C. Y., 2019 Oct 1, In : BMJ open. 9, 10, e028892.

Research output: Contribution to journalArticle

Open Access
Open Access

Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli

Tsai, S. L., Chang, Y. C., Sarvagalla, S., Wang, S., Coumar, M. S. & Cheung, C. H. A., 2019 Aug, In : Protein Expression and Purification. 160, p. 73-83 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2 Citations (Scopus)
Open Access

Electrical synapses between mushroom body neurons are critical for consolidated memory retrieval in Drosophila

Shyu, W. H., Lee, W. P., Chiang, M. H., Chang, C. C., Fu, T. F., Chiang, H. C., Wu, T. & Wu, C. L., 2019, In : PLoS genetics. 15, 5, e1008153.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Functional effects of let-7g expression in colon cancer metastasis

Chang, C. M., Wong, H. S. C., Huang, C. Y., Hsu, W. L., Maio, Z. F., Chiu, S. J., Tsai, Y. T., Chen, B. K., Wan, Y. J. Y., Wang, J. Y. & Chang, W. C., 2019 Apr, In : Cancers. 11, 4, 489.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
6 Citations (Scopus)

High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma

Lin, C. H., Li, H. Y., Liu, Y. P., Kuo, P. F., Wang, W. C., Lin, F. C., Chang, W. L., Sheu, B. S., Wang, Y. C., Hung, W. C., Cheng, H. C., Yao, Y. C., Calkins, M. J., Hsiao, M. & Lu, P. J., 2019, In : Therapeutic Advances in Medical Oncology. 11

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

LncRNA NORAD is repressed by the YAP pathway and suppresses lung and breast cancer metastasis by sequestering S100P

Tan, B. S., Yang, M. C., Singh, S., Chou, Y. C., Chen, H. Y., Wang, M. Y., Wang, Y. C. & Chen, R. H., 2019 Jul 11, In : Oncogene. 38, 28, p. 5612-5626 15 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca2+ entry

Lin, H. H., Chen, S. J., Shen, M. R., Huang, Y. T., Hsieh, H. P., Lin, S. Y., Lin, C. C., Chang, W. S. W. & Chang, J. Y., 2019 Dec, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 12, 118517.

Research output: Contribution to journalArticle

1 Citation (Scopus)