Research Output

2016
3 Citations (Scopus)

Involvement of protein phosphatases in the destabilization of methamphetamine-Associated contextual memory

Yu, Y. J., Huang, C. H., Chang, C. H. & Gean, P. W., 2016 Sep, In : Learning and Memory. 23, 9, p. 486-493 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2 Citations (Scopus)

Magnetite nanoparticle interactions with insulin amyloid fibrils

Chen, Y., Chang, C., Hung, H., Kung, M., Yeh, B. & Hsieh, S., 2016 Oct 14, In : Nanotechnology. 27, 41, p. 415702

Research output: Contribution to journalArticle

Mechanistic Study of Tetrahydrofuran-acetogenins In Triggering Endoplasmic Reticulum Stress Response-apotoposis in Human Nasopharyngeal Carcinoma

Juang, S. H., Chiang, C. Y., Liang, F. P., Chan, H. H., Yang, J. S., Wang, S. H., Lin, Y. C., Kuo, P. C., Shen, M. R., Thang, T. D., Nguyet, B. T. M., Kuo, S. C. & Wu, T. S., 2016 Dec 21, In : Scientific reports. 6, 39251.

Research output: Contribution to journalArticle

4 Citations (Scopus)

MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma

Lin, C. H., Tsai, C. H., Yeh, C. T., Liang, J. L., Hung, W. C., Lin, F. C., Chang, W. L., Li, H. Y., Yao, Y. C., Hsu, T. I., Lee, Y. C., Wang, Y. C., Sheu, B. S., Lai, W. W., Calkins, M. J., Hsiao, M. & Lu, P. J., 2016 Jan 1, In : Oncotarget. 7, 26, p. 39680-39693 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer

Jen, J., Lin, L. L., Chen, H. T., Liao, S. Y., Lo, F. Y., Tang, Y. A., Su, W. C., Salgia, R., Hsu, C. L., Huang, H. C., Juan, H. F. & Wang, Y. C., 2016 May 5, In : Oncogene. 35, 18, p. 2357-2369 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Phosphorylation of E-cadherin at threonine 790 by protein kinase Cδ reduces β-catenin binding and suppresses the function of E-cadherin

Chen, C. L., Wang, S. H., Chan, P. C., Shen, M. R. & Chen, H. C., 2016 Jan 1, In : Oncotarget. 7, 24, p. 37260-37276 17 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Prominent Vascularization Capacity of Mesenchymal Stem Cells in Collagen–Gold Nanocomposites

Hsieh, S., Chen, H., Hsu, S., Yang, Y., Tang, C., Chu, M., Lin, P., Fu, R., Kung, M., Chen, Y., Yeh, B. & Hung, H., 2016 Oct 26, In : ACS applied materials & interfaces. 8, 42, p. 28982-29000

Research output: Contribution to journalArticle

Rab-mediated vesicle trafficking in cancer

Tzeng, H. T. & Wang, Y. C., 2016 Jan 1, In : Journal of biomedical science. 23, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Refined-mapping of the novel TSG within the 17q24.3 chromosomal region in non-small cell lung cancer samples

Huang, W., Wang, Y., Chu, W. & Tseng, R., 2016 Sep, In : Oncology Letters. 12, 3, p. 1975-1980 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Seeking new surgical predictors of mesh exposure after transvaginal mesh repair

Wu, P. Y., Chang, C. H., Shen, M. R., Chou, C. Y., Yang, Y. C. & Huang, Y. F., 2016 Oct 1, In : International Urogynecology Journal. 27, 10, p. 1547-1555 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Src is required for migration, phagocytosis, and interferon beta production in Toll-like receptor-engaged macrophages

Maa, M. C. & Leu, T. H., 2016 Sep, In : BioMedicine (Netherlands). 6, 3, p. 5-9 5 p., e65.

Research output: Contribution to journalReview article

11 Citations (Scopus)

The STIM1-Orai1 pathway of store-operated Ca2+ entry controls the checkpoint in cell cycle G1/S transition

Chen, Y. W., Chen, Y. F., Chen, Y. T., Chiu, W. T. & Shen, M. R., 2016 Feb 26, In : Scientific reports. 26, 6, 22142.

Research output: Contribution to journalArticle

30 Citations (Scopus)

The store-operated Ca2+ entry-mediated signaling is important for cancer spread

Chen, Y. F., Hsu, K. F. & Shen, M. R., 2016 Jun 1, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1863, 6, p. 1427-1435 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Zinc finger proteins in cancer progression

Jen, J. & Wang, Y. C., 2016 Jul 13, In : Journal of biomedical science. 23, 1, 53.

Research output: Contribution to journalReview article

71 Citations (Scopus)

α-Carboline derivative TJY-16 inhibits tumor growth by inducing G2/M cell cycle arrest in glioma cells

Huang, H. C., Liu, W. T., Hua, K. S., Hung, H. C., Tsai, J. Y., Kuo, S. C., Huang, L. J. & Gean, P. W., 2016 Jan 19, In : Journal of biomedical science. 23, 1, 222.

Research output: Contribution to journalArticle

2 Citations (Scopus)

建立分析模組評估神經功能之方法

Shen, M-R., Chang, J-Y. & Sun, Y-T., 2016 Apr 1, Patent No. I548873

Research output: Patent

2015

Aging and exercise affect hippocampal neurogenesis via different mechanisms

Yang, T. T., Lo, C. P., Tsai, P. S., Wu, S. Y., Wang, T. F., Chen, Y. W., Jiang-Shieh, Y. F. & Kuo, Y. M., 2015 Jul 6, In : PloS one. 10, 7, e0132152.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Berberine reduces Toll-like receptor-mediated macrophage migration by suppression of Src enhancement

Cheng, W. E., Ying Chang, M., Wei, J. Y., Chen, Y. J., Maa, M. C. & Leu, T. H., 2015 Jun 15, In : European Journal of Pharmacology. 757, p. 1-10 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Clinical aspects for survivin: A crucial molecule for targeting drug-resistant cancers

Singh, N., Krishnakumar, S., Kanwar, R. K., Cheung, C. H. A. & Kanwar, J. R., 2015 May 1, In : Drug Discovery Today. 20, 5, p. 578-587 10 p.

Research output: Contribution to journalReview article

50 Citations (Scopus)

Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model

Roy, K., Kanwar, R. K., Krishnakumar, S., Cheung, C. H. A. & Kanwar, J. R., 2015 Feb 2, In : International journal of nanomedicine. 10, p. 1019-1043 25 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Deregulation of SLIT2-mediated Cdc42 activity is associated with esophageal cancer metastasis and poor prognosis

Tseng, R. C., Chang, J. M., Chen, J. H., Huang, W. R., Tang, Y. A., Kuo, I. Y., Yan, J. J., Lai, W. W. & Wang, Y. C., 2015 Jan 1, In : Journal of Thoracic Oncology. 10, 1, p. 189-198 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis

Huang, C. R., Lee, C. T., Chang, K. Y., Chang, W. C., Liu, Y. W., Lee, J. C. & Chen, B. K., 2015 Jan 1, In : Oncotarget. 6, 13, p. 11530-11546 17 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
3 Citations (Scopus)
15 Citations (Scopus)

Epidermal growth factor-induced cyclooxygenase-2 enhances head and neck squamous cell carcinoma metastasis through fibronectin up-regulation

Hsu, J. Y., Chang, K. Y., Chen, S. H., Lee, C. T., Chang, S. T., Cheng, H. C., Chang, W. C. & Chen, B. K., 2015 Jan 1, In : Oncotarget. 6, 3, p. 1723-1739 17 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Erratum: Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles (Nature Communications (2014) 5 (3356) DOI:10.1038/ncomms4356)

Chinag, H., Shin, W., Zhao, W. D., Hamid, E., Sheng, J., Baydyuk, M., Wen, P. J., Jin, A., Momboisse, F. & Wu, L. G., 2015 Jan 1, In : Nature communications. 6, 6016.

Research output: Contribution to journalComment/debate

Factor VII promotes hepatocellular carcinoma progression through ERK-TSC signaling

Tsai, M. C., Chen, K. D., Wang, C. C., Huang, K. T., Wu, C. H., Kuo, I. Y., Chen, L. Y., Hu, T. H., Goto, S., Nakano, T., Dorling, A., McVey, J. H., Chen, C. L. & Lin, C. C., 2015 Dec 21, In : Cell Death Discovery. 1, 1, 15051.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Global Oct4 target gene analysis reveals novel downstream PTEN and TNC genes required for drug-resistance and metastasis in lung cancer

Tang, Y. A., Chen, C. H., Sun, H. S., Cheng, C. P., Tseng, V. S., Hsu, H. S., Su, W. C., Lai, W. W. & Wang, Y. C., 2015 Jan 1, In : Nucleic acids research. 43, 3, p. 1593-1608 16 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Glucose regulates amyloid β production via AMPK

Yang, T. T., Shih, Y. S., Chen, Y-W., Kuo, Y-M. & Lee, C. W., 2015 Oct 1, In : Journal of Neural Transmission. 122, 10, p. 1381-1390 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Growth-arrest-specific 7C protein inhibits tumor metastasis via the N-WASP/FAK/F-actin and hnRNP U/β-TrCP/β-catenin pathways in lung cancer

Tseng, R. C., Chang, J. W., Mao, J. S., Tsai, C. D., Wu, P. C., Lin, C. J., Lu, Y. L., Liao, S. Y., Cheng, H. C., Hsu, H. S. & Wang, Y. C., 2015 Jan 1, In : Oncotarget. 6, 42, p. 44207-44221 15 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
10 Citations (Scopus)

Involvement of intracellular calcium mobilization in IL-8 activation in human retinal pigment epithelial cells

Yang, I. H., Wong, J. H., Chang, C. M., Chen, B. K., Tsai, Y. T., Chen, W. C., Wang, E. T., Hsu, W. L. & Chang, W. C., 2015 Jan 1, In : Investigative Ophthalmology and Visual Science. 56, 2, p. 761-769 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
8 Citations (Scopus)

Lipopolysaccharide-promoted proliferation of Caco-2 cells is mediated by c-Src induction and ERK activation

Lin, T. Y., Fan, C. W., Maa, M. C. & Leu, T. H., 2015 Mar 1, In : BioMedicine (Netherlands). 5, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Locked nucleic acid modified bi-specific aptamer-targeted nanoparticles carrying survivin antagonist towards effective colon cancer therapy

Roy, K., Kanwar, R. K., Antonio Cheung, C. H., Lee Fleming, C., Veedu, R. N., Krishnakumar, S. & Kanwar, J. R., 2015 Jan 1, In : RSC Advances. 5, 37, p. 29008-29016 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Mechanical phenotype of cancer cells: Cell softening and loss of stiffness sensing

Lin, H. H., Lin, H. K., Lin, I. H., Chiou, Y. W., Chen, H. W., Liu, C. Y., Harn, H. I. C., Chiu, W. T., Wang, Y. K., Shen, M. R. & Tang, M. J., 2015 Jan 1, In : Oncotarget. 6, 25, p. 20946-20958 13 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Mechanosensitive store-operated calcium entry regulates the formation of cell polarity

Huang, Y. W., Chang, S. J., I-Chen Harn, H., Huang, H. T., Lin, H. H., Shen, M. R., Tang, M. J. & Chiu, W. T., 2015 Sep 1, In : Journal of Cellular Physiology. 230, 9, p. 2086-2097 12 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

O6-methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma

Chen, S. H., Kuo, C. C., Li, C. F., Cheung, C. H. A., Tsou, T. C., Chiang, H. C., Yang, Y. N., Chang, S. L., Lin, L. C., Pan, H. Y., Chang, K. Y. & Chang, J. Y., 2015 Sep 1, In : International Journal of Cancer. 137, 6, p. 1291-1305 15 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
46 Citations (Scopus)

PTX3 gene activation in EGF-induced head and neck cancer cell metastasis

Chang, W. C., Wu, S. L., Huang, W. C., Hsu, J. Y., Chan, S. H., Wang, J. M., Tsai, J. P. & Chen, B. K., 2015 Jan 1, In : Oncotarget. 6, 10, p. 7741-7757 17 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Social isolation-induced increase in NMDA receptors in the hippocampus exacerbates emotional dysregulation in mice

Chang, C. H., Hsiao, Y. H., Chen, Y. W., Yu, Y. J. & Gean, P. W., 2015 Apr 1, In : Hippocampus. 25, 4, p. 474-485 12 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Sonic hedgehog signaling regulates amygdalar neurogenesis and extinction of fear memory

Hung, H. C., Hsiao, Y. H. & Gean, P. W., 2015 Oct, In : European Neuropsychopharmacology. 25, 10, p. 1723-1732 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers

Chi, J. Y., Hsiao, Y. W., Li, C. F., Lo, Y. C., Lin, Z. Y., Hong, J. Y., Liu, Y. M., Han, X., Wang, S. M., Chen, B. K., Tsai, K. K. & Wang, J. M., 2015 Jan 1, In : Oncotarget. 6, 27, p. 23987-24001 15 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

The iNOS/Src/FAK axis contributes to lithium chloride-mediated macrophage migration

Chen, H. C., Chien, W. C., Chang, M. Y., Hsieh, M. Y., Lai, M. D., Maa, M. C. & Leu, T. H., 2015 May 1, In : Nitric Oxide - Biology and Chemistry. 47, p. 58-64 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

TNF up-regulates Pentraxin3 expression in human airway smooth muscle cells via JNK and ERK1/2 MAPK pathways

Zhang, J., Koussih, L., Shan, L., Halayko, A. J., Chen, B. K. & Gounni, A. S., 2015 Dec 7, In : Allergy, Asthma and Clinical Immunology. 11, 1, 37.

Research output: Contribution to journalArticle

11 Citations (Scopus)

YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells

Cheng, S. M., Chang, Y. C., Liu, C. Y., Lee, J. Y. C., Chan, H. H., Kuo, C. W., Lin, K. Y., Tsai, S. L., Chen, S. H., Li, C. F., Leung, E., Kanwar, J. R., Huang, C. C., Chang, J. Y. & Cheung, C. H. A., 2015 Jan, In : British Journal of Pharmacology. 172, 1, p. 214-234 21 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2014
17 Citations (Scopus)

A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies

Huang, W. J., Tang, Y. A., Chen, M. Y., Wang, Y. J., Hu, F. H., Wang, T. W., Chao, S. W., Chiu, H. W., Yeh, Y. L., Chang, H. Y., Juan, H. F., Lin, P. & Wang, Y. C., 2014 Apr 28, In : Cancer Letters. 346, 1, p. 84-93 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)