Research Output

Lamotrigine inhibition of glutamate release from isolated cerebrocortical nerve terminals (synaptosomes) by suppression of voltage-activated calcium channel activity

Wang, S. J., Sihra, T. S. & Gean, P. W., 2001 Jul 20, In : NeuroReport. 12, 10, p. 2255-2258 4 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Lamotrigine inhibits depolarization-evoked Ca++ influx in dissociated amygdala neurons

Wang, S. J., Tsai, J. J. & Gean, P-W., 1998 Aug 1, In : Synapse. 29, 4, p. 355-362 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Lamotrigine inhibits tetraethylammonium-induced synaptic plasticity in the rat amygdala

Wang, S. J., Tsai, J. J. & Gean, P. W., 1997 Sep 26, In : Neuroscience. 81, 3, p. 667-671 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Late expression of brain-derived neurotrophic factor in the amygdala is required for persistence of fear memory

Ou, L. C., Yeh, S. H. & Gean, P. W., 2010 Mar 1, In : Neurobiology of Learning and Memory. 93, 3, p. 372-382 11 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
8 Citations (Scopus)

Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFα secretion in macrophages

Leu, T. H., Charoenfuprasert, S., Yen, C. K., Fan, C. W. & Maa, M. C., 2006 Feb 1, In : Molecular Immunology. 43, 4, p. 308-316 9 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Lipopolysaccharide-promoted proliferation of Caco-2 cells is mediated by c-Src induction and ERK activation

Lin, T. Y., Fan, C. W., Maa, M. C. & Leu, T. H., 2015 Mar 1, In : BioMedicine (Netherlands). 5, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

LncRNA NORAD is repressed by the YAP pathway and suppresses lung and breast cancer metastasis by sequestering S100P

Tan, B. S., Yang, M. C., Singh, S., Chou, Y. C., Chen, H. Y., Wang, M. Y., Wang, Y. C. & Chen, R. H., 2019 Jul 11, In : Oncogene. 38, 28, p. 5612-5626 15 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Locked nucleic acid modified bi-specific aptamer-targeted nanoparticles carrying survivin antagonist towards effective colon cancer therapy

Roy, K., Kanwar, R. K., Antonio Cheung, C. H., Lee Fleming, C., Veedu, R. N., Krishnakumar, S. & Kanwar, J. R., 2015 Jan 1, In : RSC Advances. 5, 37, p. 29008-29016 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Long-term depression of excitatory synaptic transmission the rat amygdala

Wang, S. J. & Gean, P. W., 1999 Dec 15, In : Journal of Neuroscience. 19, 24, p. 10656-10663 8 p.

Research output: Contribution to journalArticle

Open Access
56 Citations (Scopus)

Long-term enhancement of EPSP and NMDA receptor-mediated synaptic transmission in the amygdala

Po-wu, G., Fang-Chia, C., Chiung-Chun, H., Jju-Home, L. & Long-Joy, W., 1993, In : Brain Research Bulletin. 31, 1-2, p. 7-11 5 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

Cai, H., Lin, X., Xie, C., Laird, F. M., Lai, C., Wen, H., Chiang, H. C., Shim, H., Farah, M. H., Hoke, A., Price, D. L. & Wong, P. C., 2005 Aug 17, In : Journal of Neuroscience. 25, 33, p. 7567-7574 8 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Loss of heterozygosity at loci of candidate tumor suppressor genes in microdissected primary non-small cell lung cancer

Ho, W. L., Chang, J. W., Tseng, R. C., Chen, J. T., Chen, C. Y., Jou, Y. S. & Wang, Y. C., 2002 Dec 1, In : Cancer Detection and Prevention. 26, 5, p. 343-349 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Loss of p16 and/or pRb protein expression in NSCLC: An immunohistochemical and prognostic study

Chen, J. T., Chen, Y. C., Chen, C. Y. & Wang, Y. C., 2001 Feb 10, In : Lung Cancer. 31, 2-3, p. 163-170 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression

Kuo, I. Y., Wu, C. C., Chang, J. M., Huang, Y. L., Lin, C. H., Yan, J. J., Sheu, B. S., Lu, P. J., Chang, W. L., Lai, W. W. & Wang, Y. C., 2014 Aug 1, In : International Journal of Cancer. 135, 3, p. 563-573 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Low substratum rigidity of collagen gel promotes ERK phosphorylation via lipid raft to augment cell migration

Wei, W. C., Hsu, Y. C., Chiu, W. T., Wang, C. Z., Wu, C. M., Wang, Y. K., Shen, M. R. & Tang, M. J., 2008 Mar 1, In : Journal of Cellular Biochemistry. 103, 4, p. 1111-1124 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Lung cancer susceptibility and prognosis associated with polymorphisms in the nonhomologous end-joining pathway genes: A multiple genotype-phenotype study

Tseng, R. C., Hsieh, F. J., Shih, C. M., Hsu, H. S., Chen, C. Y. & Wang, Y-C., 2009 Jul 1, In : Cancer. 115, 13, p. 2939-2948 10 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca2+ entry

Lin, H. H., Chen, S. J., Shen, M. R., Huang, Y. T., Hsieh, H. P., Lin, S. Y., Lin, C. C., Chang, W. S. W. & Chang, J. Y., 2019 Dec, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 12, 118517.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Magnetite nanoparticle interactions with insulin amyloid fibrils

Chen, Y., Chang, C., Hung, H., Kung, M., Yeh, B. & Hsieh, S., 2016 Oct 14, In : Nanotechnology. 27, 41, p. 415702

Research output: Contribution to journalArticle

Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampus

Lu, K. T. & Gean, P. W., 1999 Jan 1, In : Neuroscience. 88, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Maternal diabetes modulates renal morphogenesis in offspring

Tran, S., Chen, Y. W., Chenier, I., Chan, J. S. D., Quaggin, S., Hébert, M. J., Ingelfinger, J. R. & Zhang, S. L., 2008 May 1, In : Journal of the American Society of Nephrology. 19, 5, p. 943-952 10 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Maternal diabetes programs hypertension and kidney injury in offspring

Chen, Y-W., Chenier, I., Tran, S., Scotcher, M., Chang, S. Y. & Zhang, S. L., 2010 Jul 1, In : Pediatric Nephrology. 25, 7, p. 1319-1329 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

MDM2 overexpression deregulates the transcriptional control of RB/E2F leading to DNA methyltransferase 3A overexpression in lung cancer

Tang, Y. A., Lin, R. K., Tsai, Y. T., Hsu, H. S., Yang, Y. C., Chen, C. Y. & Wang, Y. C., 2012 Aug 15, In : Clinical Cancer Research. 18, 16, p. 4325-4333 9 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Mechanical phenotype of cancer cells: Cell softening and loss of stiffness sensing

Lin, H. H., Lin, H. K., Lin, I. H., Chiou, Y. W., Chen, H. W., Liu, C. Y., Harn, H. I. C., Chiu, W. T., Wang, Y. K., Shen, M. R. & Tang, M. J., 2015 Jan 1, In : Oncotarget. 6, 25, p. 20946-20958 13 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Mechanisms underlying Benzyl alcohol cytotoxicity (triamcinolone acetonide preservative) in human retinal pigment epithelial cells

Chang, Y-S., Lin, C. F., Wu, C-L., Kuo, P. Y., Wu, F. S., Shieh, C-C., Gean, P-W., Chen, S. T., Chen, M. S., Wu, W. C., Tai, M. H. & Tseng, S. H., 2011 Jun 1, In : Investigative Ophthalmology and Visual Science. 52, 7, p. 4214-4222 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Mechanism underlying NMDA blockade-induced inhibition of aggression in post-weaning socially isolated mice

Chang, C. H., Su, C. L. & Gean, P. W., 2018 Dec, In : Neuropharmacology. 143, p. 95-105 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Mechanistic Study of Tetrahydrofuran-acetogenins In Triggering Endoplasmic Reticulum Stress Response-apotoposis in Human Nasopharyngeal Carcinoma

Juang, S. H., Chiang, C. Y., Liang, F. P., Chan, H. H., Yang, J. S., Wang, S. H., Lin, Y. C., Kuo, P. C., Shen, M. R., Thang, T. D., Nguyet, B. T. M., Kuo, S. C. & Wu, T. S., 2016 Dec 21, In : Scientific reports. 6, 39251.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Mechanosensing machinery for cells under low substratum rigidity

Wei, W. C., Lin, H. H., Shen, M. R. & Tang, M. J., 2008 Dec 1, In : American Journal of Physiology - Cell Physiology. 295, 6, p. C1579-C1589

Research output: Contribution to journalArticle

47 Citations (Scopus)

Mechanosensitive store-operated calcium entry regulates the formation of cell polarity

Huang, Y. W., Chang, S. J., I-Chen Harn, H., Huang, H. T., Lin, H. H., Shen, M. R., Tang, M. J. & Chiu, W. T., 2015 Sep 1, In : Journal of Cellular Physiology. 230, 9, p. 2086-2097 12 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Mediation of Amphetamine-Induced Long-Term Depression of Synaptic Transmission by CB1 Cannabinoid Receptors in the Rat Amygdala

Huang, Y. C., Wang, S. J., Chiou, L. C. & Gean, P. W., 2003 Nov 12, In : Journal of Neuroscience. 23, 32, p. 10311-10320 10 p.

Research output: Contribution to journalArticle

Open Access
59 Citations (Scopus)

Medical Applications of Collagen and Hyaluronan in Regenerative Medicine

Huang, L. L. H., Chen, Y. H. A., Zhuo, Z. Y., Hsieh, Y. T., Yang, C. L., Chen, W. T., Lin, J. Y., Lin, Y. X., Jiang, J. T., Zhuang, C. H., Wang, Y. C., Nguyendac, H., Lin, K. W. & Liu, W. L., 2018 Jan 1, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 285-306 22 p. (Advances in Experimental Medicine and Biology; vol. 1077).

Research output: Chapter in Book/Report/Conference proceedingChapter

MicroRNA-206 Regulates Stress-Provoked Aggressive Behaviors in Post-weaning Social Isolation Mice

Chang, C. H., Kuek, E. J. W., Su, C. L. & Gean, P. W., 2020 Jun 5, In : Molecular Therapy - Nucleic Acids. 20, p. 812-822 11 p.

Research output: Contribution to journalArticle

Open Access

Microtubule-associated histone deacetylase 6 supports the calcium store sensor STIM1 in mediating malignant cell behaviors

Chen, Y. T., Chen, Y. F., Chiu, W. T., Liu, K. Y., Liu, Y. L., Chang, J. Y., Chang, H. C. & Shen, M. R., 2013 Jul 15, In : Cancer Research. 73, 14, p. 4500-4509 10 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
11 Citations (Scopus)
21 Citations (Scopus)

Minocycline inhibits the growth of glioma by inducing autophagy

Liu, W. T., Lin, C. H., Hsiao, M. & Gean, P. W., 2011 Feb, In : Autophagy. 7, 2, p. 166-175 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy

Chen, Y. F., Chen, L. H., Yeh, Y. M., Wu, P. Y., Chen, Y. F., Chang, L. Y., Chang, J. Y. & Shen, M. R., 2017 Mar 28, In : Scientific reports. 7, 45366.

Research output: Contribution to journalArticle

8 Citations (Scopus)

MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma

Lin, C. H., Tsai, C. H., Yeh, C. T., Liang, J. L., Hung, W. C., Lin, F. C., Chang, W. L., Li, H. Y., Yao, Y. C., Hsu, T. I., Lee, Y. C., Wang, Y. C., Sheu, B. S., Lai, W. W., Calkins, M. J., Hsiao, M. & Lu, P. J., 2016, In : Oncotarget. 7, 26, p. 39680-39693 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells

Lin, R. K., Hsu, C. H. & Wang, Y-C., 2007 Nov 1, In : Anti-Cancer Drugs. 18, 10, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Mitochondrial apoptosis and FAK signaling disruption by a novel histone deacetylase inhibitor, HTPB, in antitumor and antimetastatic mouse models

Shieh, J. M., Wei, T. T., Tang, Y. A., Huang, S. M., Wen, W. L., Chen, M. Y., Cheng, H. C., Salunke, S. B., Chen, C. S., Lin, P., Chen, C. T. & Wang, Y. C., 2012 Jan 18, In : PloS one. 7, 1, e30240.

Research output: Contribution to journalArticle

17 Citations (Scopus)

MJ-66 induces malignant glioma cells G2/M phase arrest and mitotic catastrophe through regulation of cyclin B1/Cdk1 complex

Liu, W. T., Chen, C., Lu, I. C., Kuo, S. C., Lee, K. H., Chen, T. L., Song, T. S., Lu, Y. L., Gean, P. W. & Hour, M. J., 2014 Aug 19, In : Neuropharmacology. 86, p. 219-227 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer

Ma, L., Qiao, H., He, C., Yang, Q., Cheung, C. H. A., Kanwar, J. R. & Sun, X., 2012 Apr 1, In : Investigational New Drugs. 30, 2, p. 508-517 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Modulation of voltage-dependent calcium currents by serotonin in acutely isolated rat amygdala neurons

Lin, C. H., Huang, Y. C., Tsai, J. J. & Gean, P. W., 2001 Sep 15, In : Synapse. 41, 4, p. 351-359 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
32 Citations (Scopus)

Molecular and functional identification of the Na + /H + exchange isoforms NHE1 and NHE3 in isolated bovine articular chondrocytes

Tattersall, A. L., Meredith, D., Furla, P., Shen, M-R., Ellory, J. C. & Wilkins, R. J., 2003 Jan 1, In : Cellular Physiology and Biochemistry. 13, 4, p. 215-222 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Molecular diagnostic markers for lung cancer in sputum and plasma

Wang, Y. C., Hsu, H. S., Chen, T. P. & Chen, J. T., 2006 Sep, Circulating Nucleic Acids in Plasma and Serum IV. Blackwell Publishing Inc., p. 179-184 6 p. (Annals of the New York Academy of Sciences; vol. 1075).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

46 Citations (Scopus)
3 Citations (Scopus)

Most vesicles in a central nerve terminal participate in recycling

Xue, L., Sheng, J., Wu, X. S., Wu, W., Luo, F., Shin, W., Chiang, H. C. & Wu, L. G., 2013 May 15, In : Journal of Neuroscience. 33, 20, p. 8820-8826 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Motor protein-dependent membrane trafficking of KCl cotransporter-4 is important for cancer cell invasion

Chen, Y. F., Chou, C. Y., Wilkins, R. J., Ellory, J. C., Mount, D. B. & Shen, M. R., 2009 Nov 15, In : Cancer Research. 69, 22, p. 8585-8593 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Multiple genetic and epigenetic biomarkers for lung cancer detection in cytologically negative sputum and a nested case-control study for risk assessment

Hsu, H. S., Chen, T. P., Wen, C. K., Hung, C. H., Chen, C. Y., Chen, J. T. & Wang, Y. C., 2007 Dec 1, In : Journal of Pathology. 213, 4, p. 412-419 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)