Research Output

Article

Mechanosensing machinery for cells under low substratum rigidity

Wei, W. C., Lin, H. H., Shen, M. R. & Tang, M. J., 2008 Dec 1, In : American Journal of Physiology - Cell Physiology. 295, 6, p. C1579-C1589

Research output: Contribution to journalArticle

47 Citations (Scopus)

Mechanosensitive store-operated calcium entry regulates the formation of cell polarity

Huang, Y. W., Chang, S. J., I-Chen Harn, H., Huang, H. T., Lin, H. H., Shen, M. R., Tang, M. J. & Chiu, W. T., 2015 Sep 1, In : Journal of Cellular Physiology. 230, 9, p. 2086-2097 12 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Mediation of Amphetamine-Induced Long-Term Depression of Synaptic Transmission by CB1 Cannabinoid Receptors in the Rat Amygdala

Huang, Y. C., Wang, S. J., Chiou, L. C. & Gean, P. W., 2003 Nov 12, In : Journal of Neuroscience. 23, 32, p. 10311-10320 10 p.

Research output: Contribution to journalArticle

Open Access
59 Citations (Scopus)

MicroRNA-206 Regulates Stress-Provoked Aggressive Behaviors in Post-weaning Social Isolation Mice

Chang, C. H., Kuek, E. J. W., Su, C. L. & Gean, P. W., 2020 Jun 5, In : Molecular Therapy - Nucleic Acids. 20, p. 812-822 11 p.

Research output: Contribution to journalArticle

Open Access

Microtubule-associated histone deacetylase 6 supports the calcium store sensor STIM1 in mediating malignant cell behaviors

Chen, Y. T., Chen, Y. F., Chiu, W. T., Liu, K. Y., Liu, Y. L., Chang, J. Y., Chang, H. C. & Shen, M. R., 2013 Jul 15, In : Cancer Research. 73, 14, p. 4500-4509 10 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
11 Citations (Scopus)
21 Citations (Scopus)

Minocycline inhibits the growth of glioma by inducing autophagy

Liu, W. T., Lin, C. H., Hsiao, M. & Gean, P. W., 2011 Feb, In : Autophagy. 7, 2, p. 166-175 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy

Chen, Y. F., Chen, L. H., Yeh, Y. M., Wu, P. Y., Chen, Y. F., Chang, L. Y., Chang, J. Y. & Shen, M. R., 2017 Mar 28, In : Scientific reports. 7, 45366.

Research output: Contribution to journalArticle

8 Citations (Scopus)

MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma

Lin, C. H., Tsai, C. H., Yeh, C. T., Liang, J. L., Hung, W. C., Lin, F. C., Chang, W. L., Li, H. Y., Yao, Y. C., Hsu, T. I., Lee, Y. C., Wang, Y. C., Sheu, B. S., Lai, W. W., Calkins, M. J., Hsiao, M. & Lu, P. J., 2016, In : Oncotarget. 7, 26, p. 39680-39693 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells

Lin, R. K., Hsu, C. H. & Wang, Y-C., 2007 Nov 1, In : Anti-Cancer Drugs. 18, 10, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Mitochondrial apoptosis and FAK signaling disruption by a novel histone deacetylase inhibitor, HTPB, in antitumor and antimetastatic mouse models

Shieh, J. M., Wei, T. T., Tang, Y. A., Huang, S. M., Wen, W. L., Chen, M. Y., Cheng, H. C., Salunke, S. B., Chen, C. S., Lin, P., Chen, C. T. & Wang, Y. C., 2012 Jan 18, In : PloS one. 7, 1, e30240.

Research output: Contribution to journalArticle

17 Citations (Scopus)

MJ-66 induces malignant glioma cells G2/M phase arrest and mitotic catastrophe through regulation of cyclin B1/Cdk1 complex

Liu, W. T., Chen, C., Lu, I. C., Kuo, S. C., Lee, K. H., Chen, T. L., Song, T. S., Lu, Y. L., Gean, P. W. & Hour, M. J., 2014 Aug 19, In : Neuropharmacology. 86, p. 219-227 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer

Ma, L., Qiao, H., He, C., Yang, Q., Cheung, C. H. A., Kanwar, J. R. & Sun, X., 2012 Apr 1, In : Investigational New Drugs. 30, 2, p. 508-517 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Modulation of voltage-dependent calcium currents by serotonin in acutely isolated rat amygdala neurons

Lin, C. H., Huang, Y. C., Tsai, J. J. & Gean, P. W., 2001 Sep 15, In : Synapse. 41, 4, p. 351-359 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
32 Citations (Scopus)

Molecular and functional identification of the Na + /H + exchange isoforms NHE1 and NHE3 in isolated bovine articular chondrocytes

Tattersall, A. L., Meredith, D., Furla, P., Shen, M-R., Ellory, J. C. & Wilkins, R. J., 2003 Jan 1, In : Cellular Physiology and Biochemistry. 13, 4, p. 215-222 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
3 Citations (Scopus)

Most vesicles in a central nerve terminal participate in recycling

Xue, L., Sheng, J., Wu, X. S., Wu, W., Luo, F., Shin, W., Chiang, H. C. & Wu, L. G., 2013 May 15, In : Journal of Neuroscience. 33, 20, p. 8820-8826 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Motor protein-dependent membrane trafficking of KCl cotransporter-4 is important for cancer cell invasion

Chen, Y. F., Chou, C. Y., Wilkins, R. J., Ellory, J. C., Mount, D. B. & Shen, M. R., 2009 Nov 15, In : Cancer Research. 69, 22, p. 8585-8593 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Multiple genetic and epigenetic biomarkers for lung cancer detection in cytologically negative sputum and a nested case-control study for risk assessment

Hsu, H. S., Chen, T. P., Wen, C. K., Hung, C. H., Chen, C. Y., Chen, J. T. & Wang, Y. C., 2007 Dec 1, In : Journal of Pathology. 213, 4, p. 412-419 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Multiple origins of replication in the dihydrofolate reductase amplicons of a methotrexate-resistant Chinese hamster cell line

Ma, C., Leu, T-H. & Hamlin, J. L., 1990 Jan 1, In : Molecular and Cellular Biology. 10, 4, p. 1338-1346 9 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Muscarinic depression of excitatory synaptic transmission mediated by the presynaptic M3 receptors in the rat neostriatum

Hsu, K. S., Huang, C. C. & Gean, P. W., 1995 Sep 8, In : Neuroscience Letters. 197, 2, p. 141-144 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Mushroom body glycolysis is required for olfactory memory in Drosophila

Wu, C. L., Chang, C. C., Wu, J. K., Chiang, M. H., Yang, C. H. & Chiang, H. C., 2018 Apr, In : Neurobiology of Learning and Memory. 150, p. 13-19 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Mutation of the PTCH1 gene predicts recurrence of breast cancer

Wang, C. Y., Chang, Y. C., Kuo, Y. L., Lee, K. T., Chen, P. S., Cheung, C. H. A., Chang, C. P., Phan, N. N., Shen, M. R. & Hsu, H. P., 2019 Nov 8, In : Scientific reports. 9, 1, 1 p., 16359.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Myosin light chain kinase modulates hypotonicity-induced Ca2+ entry and Cl- channel activity in human cervical cancer cells

Shen, M-R., Furla, P., Chou, C-Y. & Ellory, C. J., 2002 May 22, In : Pflugers Archiv European Journal of Physiology. 444, 1-2, p. 276-285 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Myostatin Is Associated With Cognitive Decline in an Animal Model of Alzheimer’s Disease

Lin, Y. S., Lin, F. Y. & Hsiao, Y. H., 2019 Mar 1, In : Molecular Neurobiology. 56, 3, p. 1984-1991 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
16 Citations (Scopus)

Network-based analysis identifies epigenetic biomarkers of esophageal squamous cell carcinoma progression

Cheng, C. P., Kuo, I. Y., Alakus, H., Frazer, K. A., Harismendy, O., Wang, Y. C. & Tseng, V. S., 2014 May 28, In : Bioinformatics. 30, 21, p. 3054-3061 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Neuroprotective effect of N-acetylcysteine on neuronal apoptosis induced by a synthetic gingerdione compound: Involvement of ERK and p38 phosphorylation

Lin, C. H., Kuo, S. C., Huang, L. J. & Gean, P-W., 2006 Nov 15, In : Journal of Neuroscience Research. 84, 7, p. 1485-1494 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Neuroprotective effects of furopyrazole derivative of benzylindazole analogs on C2 ceramide-induced apoptosis in cultured cortical neurons

Lin, Y. C., Chou, L. C., Chen, S. C., Kuo, S. C., Huang, L. J. & Gean, P. W., 2009 Jun 15, In : Bioorganic and Medicinal Chemistry Letters. 19, 12, p. 3225-3228 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Neuroprotective Effects of Ugonin K on Hydrogen Peroxide-Induced Cell Death in Human Neuroblastoma SH-SY5Y Cells

Lin, Y. C., Huang, Y. C., Chen, S. C., Liaw, C. C., Kuo, S. C., Huang, L. J. & Gean, P-W., 2009 May 1, In : Neurochemical Research. 34, 5, p. 923-930 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
15 Citations (Scopus)

Novel 2-step synthetic indole compound 1,1,3-tri(3-indolyl)cyclohexane inhibits cancer cell growth in lung cancer cells and xenograft models

Lee, C. H., Yao, C. F., Huang, S. M., Ko, S., Tan, Y. H., Lee-Chen, G. J. & Wang, Y. C., 2008 Aug 15, In : Cancer. 113, 4, p. 815-825 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Novel lead generation through hypothetical pharmacophore three-dimensional database searching: Discovery of isoflavonoids as nonsteroidal inhibitors of rat 5α-reductase

Chen, G. S., Chang, C. S., Kan, W-M., Chang, C. L., Wang, K. C. & Chern, J. W., 2001 Nov 8, In : Journal of Medicinal Chemistry. 44, 23, p. 3759-3763 5 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2α in phorbol ester-treated non-small cell lung cancer A549 cells

Tsou, J. H., Chang, K. Y., Wang, W. C., Tseng, J. T., Su, W. C., Hung, L. Y., Chang, W. C. & Chen, B. K., 2008 Jan 1, In : Nucleic acids research. 36, 1, p. 217-227 11 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

O6-methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma

Chen, S. H., Kuo, C. C., Li, C. F., Cheung, C. H. A., Tsou, T. C., Chiang, H. C., Yang, Y. N., Chang, S. L., Lin, L. C., Pan, H. Y., Chang, K. Y. & Chang, J. Y., 2015 Sep 1, In : International Journal of Cancer. 137, 6, p. 1291-1305 15 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression

Jen, J., Tang, Y. A., Lu, Y. H., Lin, C. C., Lai, W. W. & Wang, Y. C., 2017 Jan 1, In : Molecular cancer. 16, 1, 104.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Oleate-induced PTX3 promotes head and neck squamous cell carcinoma metastasis through the up-regulation of vimentin

Chan, S. H., Tsai, J. P., Shen, C. J., Liao, Y. H. & Chen, B. K., 2017, In : Oncotarget. 8, 25, p. 41364-41378 15 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Oleic acid-induced ANGPTL4 enhances head and neck squamous cell carcinoma anoikis resistance and metastasis via up-regulation of fibronectin

Shen, C. J., Chan, S-H., Lee, C-T., Huang, W. C., Tsai, J. P. & Chen, B-K., 2017 Feb 1, In : Cancer Letters. 386, p. 110-122 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Oleic acid-induced NOX4 is dependent on ANGPTL4 expression to promote human colorectal cancer metastasis

Shen, C. J., Chang, K. Y., Lin, B. W., Lin, W. T., Su, C. M., Tsai, J. P., Liao, Y. H., Hung, L. Y., Chang, W. C. & Chen, B. K., 2020, In : Theranostics. 10, 16, p. 7083-7099 17 p.

Research output: Contribution to journalArticle

Open Access

Oncogenic MCT-1 activation promotes YY1-EGFR-MnSOD signaling and tumor progression

Tseng, H., Chen, Y., Jen, J., Shen, P., Chen, L., Lin, T., Wang, Y-C. & Hsu, H., 2017 Apr 1, In : Oncogenesis. 6, 4, p. e313-e313

Research output: Contribution to journalArticle

11 Citations (Scopus)
3 Citations (Scopus)

Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer

Jen, J., Lin, L. L., Chen, H. T., Liao, S. Y., Lo, F. Y., Tang, Y. A., Su, W. C., Salgia, R., Hsu, C. L., Huang, H. C., Juan, H. F. & Wang, Y. C., 2016 May 5, In : Oncogene. 35, 18, p. 2357-2369 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

One-pot synthesis of ene-lactams via N-debenzylation of keto-containing N-2,4-dimethoxylbenzylamides

Kan, W. M., Cheng, C. L. & Chern, C. Y., 2004 Dec 30, In : Synthetic Communications. 34, 23, p. 4257-4264 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Organization and genesis of dihydrofolate reductase amplicons in the genome of a methotrexate-resistant Chinese hamster ovary cell line

Ma, C., Looney, J. E., Leu, T-H. & Hamlin, J. L., 1988 Jan 1, In : Molecular and Cellular Biology. 8, 6, p. 2316-2327 12 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Origins of replication: timing and chromosomal position

Hamlin, J. L., Vaughn, J. P., Dijkwel, P. A., Leu, T. H. & Ma, C., 1991 Jun, In : Current Opinion in Cell Biology. 3, 3, p. 414-421 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
18 Citations (Scopus)

Overexpression of c-Fos enhances the transcription of human arachidonate 12-lipoxygenase in A431 cells

Chen, B. K. & Chang, W. C., 1999 Aug 11, In : Biochemical and Biophysical Research Communications. 261, 3, p. 848-852 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)