Research Output

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

Cai, Z., Jitkaew, S., Zhao, J., Chiang, H. C., Choksi, S., Liu, J., Ward, Y., Wu, L. G. & Liu, Z. G., 2014 Jan 1, In : Nature Cell Biology. 16, 1, p. 55-65 11 p.

Research output: Contribution to journalArticle

457 Citations (Scopus)

Poly ADP-ribose polymerase inhibition suppresses cisplatin toxicity in chronic myeloid leukemia cells

Xiao, L. Y. & Kan, W. M., 2017 Jan 1, In : Anti-Cancer Drugs. 28, 3, p. 316-321 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Polymorphism in the hMSH2 gene (gISV12-6T > C) is a prognostic factor in non-small cell lung cancer

Hsu, H. S., Lee, I. H., Hsu, W. H., Kao, W. T. & Wang, Y. C., 2007 Oct 1, In : Lung Cancer. 58, 1, p. 123-130 8 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Polymorphisms of p53 and p21 genes in chronic obstructive pulmonary disease

Lee, Y. L., Chen, W., Tsai, W. K., Lee, J. C., Chiou, H. L., Shih, C. M. & Wang, Y-C., 2006 May 1, In : Journal of Laboratory and Clinical Medicine. 147, 5, p. 228-233 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Post-fusion structural changes and their roles in exocytosis and endocytosis of dense-core vesicles

Chiang, H. C., Shin, W., Zhao, W. D., Hamid, E., Sheng, J., Baydyuk, M., Wen, P. J., Jin, A., Momboisse, F. & Wu, L. G., 2014 Feb 24, In : Nature communications. 5, 3356.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: Implications for the etiology of multiple human cancers

Maa, M. C., Leu, T. H., Mccarley, D. J., Schatzman, R. C. & Parsons, S. J., 1995 Jul 18, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 15, p. 6981-6985 5 p.

Research output: Contribution to journalArticle

268 Citations (Scopus)

Potentiation of N-methyl-D-aspartate currents by isoproterenol in the acutely dissociated rat amygdalar neurons

Huang, C. C., Lin, C. H. & Gean, P. W., 1998 Aug 28, In : Neuroscience Letters. 253, 1, p. 9-12 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells

Chen, B. K., Huang, C. C., Chang, W. C., Chen, Y. J., Kikkawa, U., Nakahama, K. I., Morita, I. & Chang, W. C., 2007 Mar 1, In : Molecular Biology of the Cell. 18, 3, p. 1118-1127 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Prediction for Intravenous Immunoglobulin Resistance by Using Weighted Genetic Risk Score Identified from Genome-Wide Association Study in Kawasaki Disease

Kuo, H. C., Wong, H. S. C., Chang, W. P., Chen, B. K., Wu, M. S., Yang, K. D., Hsieh, K. S., Hsu, Y. W., Liu, S. F., Liu, X. & Chang, W. C., 2017 Oct 1, In : Circulation: Cardiovascular Genetics. 10, 5, e001625.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Prenatal sonographic diagnosis of single umbilical artery

Wu, M. H., Chang, F. M., Shen, M. R., Yao, B. L., Chang, C. H., Yu, C. H., Hsu, C. C. & Huang, K. E., 1997 Oct, In : Journal of Clinical Ultrasound. 25, 8, p. 425-430 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Presynaptic D2 dopaminergic receptors mediate inhibition of excitatory synaptic transmission in rat neostriatum

Hsu, K-S., Huang, C. C., Yang, C. H. & Gean, P-W., 1995 Sep 4, In : Brain Research. 690, 2, p. 264-268 5 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Presynaptic inhibition of excitatory neurotransmission by lamotrigine in the rat amygdalar neurons

Wang, S. J., Huang, C. C., Hsu, K-S., Tsai, J. J. & Gean, P-W., 1996 Nov 1, In : Synapse. 24, 3, p. 248-255 8 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Prognostic CpG methylation biomarkers identified by methylation array in esophageal squamous cell carcinoma patients

Kuo, I. Y., Chang, J. M., Jiang, S. S., Chen, C. H., Chang, I. S., Sheu, B. S., Lu, P. J., Chang, W. L., Lai, W. W. & Wang, Y. C., 2014 May 30, In : International Journal of Medical Sciences. 11, 8, p. 779-787 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Prognostic significance of p53 codon 72 polymorphism in lung carcinomas

Wang, Y. C., Lee, H. S., Chen, S. K., Chang, Y. Y. & Chen, C. Y., 1999 Feb 1, In : European Journal of Cancer. 35, 2, p. 226-230 5 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Proliferative and protective effects of SurR9-C84A on differentiated neural cells

Baratchi, S., Kanwar, R. K., Cheung, C. H. A. & Kanwar, J. R., 2010 Oct 1, In : Journal of Neuroimmunology. 227, 1-2, p. 120-132 13 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Prominent Vascularization Capacity of Mesenchymal Stem Cells in Collagen–Gold Nanocomposites

Hsieh, S., Chen, H., Hsu, S., Yang, Y., Tang, C., Chu, M., Lin, P., Fu, R., Kung, M., Chen, Y., Yeh, B. & Hung, H., 2016 Oct 26, In : ACS applied materials & interfaces. 8, 42, p. 28982-29000

Research output: Contribution to journalArticle

Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer

Hsu, H. S., Wen, C. K., Tang, Y. A., Lin, R. K., Li, W. Y., Hsu, W. H. & Wang, Y. C., 2005 Aug 1, In : Clinical Cancer Research. 11, 15, p. 5410-5416 7 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Promoter methylation of the hMLH1 gene and protein expression of human mutL homolog 1 and human mutS homolog 2 in resected esophageal squamous cell carcinoma

Tzao, C., Hsu, H. S., Sun, G. H., Lai, H. L., Wang, Y. C., Tung, H. J., Yu, C. P., Cheng, Y. L. & Lee, S. C., 2005 Nov, In : Journal of Thoracic and Cardiovascular Surgery. 130, 5, p. 1371.e1-1371.e8

Research output: Contribution to journalArticle

34 Citations (Scopus)

Promotion of forskolin-induced long-term potentiation of synaptic transmission by caffeine in area CA1 of the rat hippocampus

Lu, K. T., Wu, S. P. & Gean, P-W., 1999 Dec 31, In : Chinese Journal of Physiology. 42, 4, p. 249-253 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Protein Glycation by Glyoxal Promotes Amyloid Formation by Islet Amyloid Polypeptide

Hsu, Y. H., Chen, Y. W., Wu, M. H. & Tu, L. H., 2019 Jun 18, In : Biophysical Journal. 116, 12, p. 2304-2313 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

PTX3 gene activation in EGF-induced head and neck cancer cell metastasis

Chang, W. C., Wu, S. L., Huang, W. C., Hsu, J. Y., Chan, S. H., Wang, J. M., Tsai, J. P. & Chen, B. K., 2015, In : Oncotarget. 6, 10, p. 7741-7757 17 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Rab37 in lung cancer mediates exocytosis of soluble ST2 and thus skews macrophages toward tumor-suppressing phenotype

Tzeng, H. T., Su, C. C., Chang, C. P., Lai, W. W., Su, W. C. & Wang, Y-C., 2018 Oct 1, In : International Journal of Cancer. 143, 7, p. 1753-1763 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
4 Citations (Scopus)

Rab-mediated vesicle trafficking in cancer

Tzeng, H. T. & Wang, Y. C., 2016 Jan 1, In : Journal of biomedical science. 23, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Rapid growth of a fetal abdominal mass: A case report of congenital neuroblastoma

Shen, M. R., Lin, Y. S., Huang, S. C. & Chou, C. Y., 1997 Jan 1, In : Journal of Clinical Ultrasound. 25, 1, p. 39-42 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Reactive oxygen species and nuclear factor-kappa B pathway mediate high glucose-induced Pax-2 gene expression in mouse embryonic mesenchymal epithelial cells and kidney explants

Chen, Y. W., Liu, F., Tran, S., Zhu, Y., Hébert, M. J., Ingelfinger, J. R. & Zhang, S. L., 2006 Nov 1, In : Kidney international. 70, 9, p. 1607-1615 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Reactive oxygen species in the presence of high glucose alter ureteric bud morphogenesis

Zhang, S. L., Chen, Y. W., Tran, S., Chenier, I., Hébert, M. J. & Ingelfinger, J. R., 2007 Jul, In : Journal of the American Society of Nephrology. 18, 7, p. 2105-2115 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Recent advances in anti-survivin treatments for cancer

Kanwar, R. K., Cheung, C-H., Chang, J-Y. & Kanwar, J. R., 2010 Jun 18, In : Current Medicinal Chemistry. 17, 15, p. 1509-1515 7 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Reduced Acetylated Histone H4 is Associated With Promoter Methylation of the Fragile Histidine Triad Gene in Resected Esophageal Squamous Cell Carcinoma

Tzao, C., Sun, G. H., Tung, H. J., Hsu, H. S., Hsu, W. H., Wang, Y. C., Cheng, Y. L. & Lee, S. C., 2006 Aug, In : Annals of Thoracic Surgery. 82, 2, p. 396-401 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Reduced axin protein expression is associated with a poor prognosis in patients with squamous cell carcinoma of esophagus

Li, A. F. Y., Hsu, P. K., Tzao, C., Wang, Y-C., Hung, I. C., Huang, M. H. & Hsu, H. S., 2009 Sep 1, In : Annals of Surgical Oncology. 16, 9, p. 2486-2493 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Reduced membranous β-catenin protein expression is associated with metastasis and poor prognosis in squamous cell carcinoma of the esophagus

Hsu, P. K., Li, A. F. Y., Wang, Y. C., Hsieh, C. C., Huang, M. H., Hsu, W. H. & Hsu, H. S., 2008 May 1, In : Journal of Thoracic and Cardiovascular Surgery. 135, 5, p. 1029-1035 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Refined-mapping of the novel TSG within the 17q24.3 chromosomal region in non-small cell lung cancer samples

Huang, W., Wang, Y., Chu, W. & Tseng, R., 2016 Sep, In : Oncology Letters. 12, 3, p. 1975-1980 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Regulation of 12-lipoxygenase expression by epidermal growth factor in human epidermoid carcinoma A431 cells

Chang, W. C., Liu, Y. W., Chen, B-K. & Chen, C. J., 1996 Dec 1, In : Advances in Experimental Medicine and Biology. 407, p. 33-40 8 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Relative D3 vitamin deficiency and consequent cognitive impairment in an animal model of Alzheimer's disease: Potential involvement of collapsin response mediator protein-2

Lin, F. Y., Lin, Y. F., Lin, Y. S., Yang, C. M., Wang, C. C. & Hsiao, Y. H., 2020 Mar 1, In : Neuropharmacology. 164, 107910.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Remodeling of calcium signaling in tumor progression

Chen, Y. F., Chen, Y. T., Chiu, W. T. & Shen, M. R., 2013 Apr 19, In : Journal of biomedical science. 20, 1, 23.

Research output: Contribution to journalReview article

112 Citations (Scopus)

Repetitive sequence elements in an initiation locus of the amplified dihydrofolate reductase domain in CHO cells

Leu, T. H., Anachkova, B. & Hamlin, J. L., 1990 Jul, In : Genomics. 7, 3, p. 428-433 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Requirement of inducible nitric-oxide synthase in lipopolysaccharide- mediated Src induction and macrophage migration

Maa, M. C., Miao, Y. C., Chen, Y. J., Lin, C. H., Chih, J. Y., Yi, L. Y., Li, J., Chen, P. R., Tang, C. H., Lei, H. Y. & Leu, T-H., 2008 Nov 14, In : Journal of Biological Chemistry. 283, 46, p. 31408-31416 9 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Role of transcriptional factors Sp1, c-Rel, and c-Jun in LPS-induced C/EBPd gene expression of mouse macrophages

Liu, Y. W., Chen, C. C., Wang, J-M., Chang, W. C., Huang, Y. C., Chung, S. Y., Chen, B-K. & Hung, J-J., 2007 Dec 1, In : Cellular and Molecular Life Sciences. 64, 24, p. 3282-3294 13 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Roles of testosterone and amygdaloid LTP induction in determining sex differences in fear memory magnitude

Chen, L. S., Tzeng, W. Y., Chuang, J. Y., Cherng, C. G., Gean, P. W. & Yu, L., 2014 Aug, In : Hormones and Behavior. 66, 3, p. 498-508 11 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Seeking new surgical predictors of mesh exposure after transvaginal mesh repair

Wu, P. Y., Chang, C. H., Shen, M. R., Chou, C. Y., Yang, Y. C. & Huang, Y. F., 2016 Oct 1, In : International Urogynecology Journal. 27, 10, p. 1547-1555 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Selective enhancement of L-type calcium currents by corticotropin in acutely isolated rat amygdala neurons

Young, C., Huang, Y. C., Lin, C. H., Shen, Y. Z. & Gean, P. W., 2001 Jan 1, In : Molecular Pharmacology. 59, 3, p. 604-611 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Selective enhancement of P-type calcium currents by isoproterenol in the rat amygdala

Huang, C. C., Wang, S. J. & Gean, P. W., 1998 Mar 15, In : Journal of Neuroscience. 18, 6, p. 2276-2282 7 p.

Research output: Contribution to journalArticle

Open Access
39 Citations (Scopus)

Selective inhibition of early-but not late-expressed HIF-1α is neuroprotective in rats after focal ischemic brain damage

Yeh, S. H., Ou, L. C., Gean, P-W., Hung, J-J. & Chang, W. C., 2011 May 1, In : Brain Pathology. 21, 3, p. 249-262 14 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Selective N-debenzylation of amides with p-TsOH

Chern, C. Y., Huang, Y. P. & Kan, W. M., 2003 Jan 27, In : Tetrahedron Letters. 44, 5, p. 1039-1041 3 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Selective serotonin reuptake inhibitor, fluoxetine, impairs E-cadherin-mediated cell adhesion and alters calcium homeostasis in pancreatic beta cells

Chang, H. Y., Chen, S. L., Shen, M. R., Kung, M. L., Chuang, L. M. & Chen, Y. W., 2017 Dec 1, In : Scientific reports. 7, 1, 3515.

Research output: Contribution to journalArticle

6 Citations (Scopus)
94 Citations (Scopus)

Significance of migration-related genes (S100A9, MAGED4, C8orf30A, IL-8) in esophageal squamous cell carcinoma

Huang, C. T., Huang, G. C., Wu, P. S., Wu, L. W., Lin, S. H., Lai, W. W., Wang, Y. C. & Liu, H. S., 2012 Mar 1, In : Genomic Medicine, Biomarkers, and Health Sciences. 4, 1-2, p. 16-18 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)