Institute of Basic Medical Sciences

Research Output 1989 2019

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Review article
2018
2 Citations (Scopus)
Oxytocin Receptors
Neuronal Plasticity
Oxytocin
Hippocampus
Cognitive Therapy
5 Citations (Scopus)

WWOX phosphorylation, signaling, and role in neurodegeneration

Liu, C. C., Ho, P. C., Lee, I. T., Chen, Y. A., Chu, C-H., Teng, C. C., Wu, S-N., Sze, C-I., Chiang, M. F. & Chang, N-S., 2018 Aug 15, In : Frontiers in Neuroscience. 12, AUG, 563.

Research output: Contribution to journalReview article

Amyloid
Phosphorylation
Genetic Suppression
Glycogen Synthase Kinase 3
Proteins
2017

Could inactivation of platelets be key to preventing thrombocytopenia in dengue virus infected patients?

Lo, Y. C., Chien, Y. W. & Perng, G. C., 2017 Jul, In : Future Virology. 12, 7, p. 321-323 3 p.

Research output: Contribution to journalReview article

2016
2 Citations (Scopus)

Novel concept on antiviral strategies to dengue

Lo, Y-C. & Perng, G-C., 2016 Jun 1, In : Current Opinion in Virology. 18, p. 97-108 12 p.

Research output: Contribution to journalReview article

Dengue
Antiviral Agents
Dengue Virus
Confounding Factors (Epidemiology)
Virus Diseases
2015
43 Citations (Scopus)

Biomarkers of severe dengue disease - A review

John, D. V., Lin, Y. S. & Perng, G. C., 2015 Oct 14, In : Journal of biomedical science. 22, 1, 191.

Research output: Contribution to journalReview article

Severe Dengue
Endothelial cells
Biomarkers
Chemical activation
Cytokines
7 Citations (Scopus)

Current neurological observations and complications of dengue virus infection

Solbrig, M. V. & Perng, G-C., 2015 Jun 1, In : Current Neurology and Neuroscience Reports. 15, 6, p. 1-8 8 p.

Research output: Contribution to journalReview article

Dengue Virus
Dengue
Virus Diseases
Flavivirus
Explosions
15 Citations (Scopus)

Pathological functions of hypoxia in endometriosis

Hsiao, K. Y., Lin, S-C., Wu, M-H. & Tsai, S-J., 2015 Jan 1, In : Frontiers in bioscience (Elite edition). 7, p. 309-321 13 p.

Research output: Contribution to journalReview article

Endometriosis
Cyclooxygenase 2
Dinoprostone
Estrogens
Genes
2014
1 Citation (Scopus)

Impacts of protease inhibitors on clathrin and fibronectin in cancer metastasis

Wu, C. I., Chang, M. M., Su, C. L., Ling, P., Chang, W. T. & Cheng, H. C., 2014 Jan 1, In : Biomarkers and Genomic Medicine. 6, 1, p. 23-31 9 p.

Research output: Contribution to journalReview article

Clathrin
Protease Inhibitors
Fibronectins
Neoplasm Metastasis
Biomarkers
2013
14 Citations (Scopus)

Challenges for the formulation of a universal vaccine against dengue

Chokephaibulkit, K. & Perng, G-C., 2013 Aug 1, In : Experimental Biology and Medicine. 238, 5, p. 566-578 13 p.

Research output: Contribution to journalReview article

Dengue Vaccines
Severe Dengue
Dengue
Vaccines
Immunity
5 Citations (Scopus)

Immunologic hypo- or non-responder in natural dengue virus infection

Perng, G-C. & Chokephaibulkit, K., 2013 Jun 5, In : Journal of biomedical science. 20, 1, 34.

Research output: Contribution to journalReview article

Dengue Virus
Dengue
Virus Diseases
Viruses
Severe Dengue
8 Citations (Scopus)

Role of cognitive parameters in dengue hemorrhagic fever and dengue shock syndrome

Tsai, J. J., Chokephaibulkit, K., Chen, P. C., Liu, L. T., Hsiao, H. M., Lo, Y. C. & Perng, G. C., 2013 Dec 5, In : Journal of biomedical science. 20, 1, 88.

Research output: Contribution to journalReview article

Geographical distribution
Severe Dengue
Dengue
Medical problems
Endotoxins
2012
15 Citations (Scopus)

The importance of hematopoietic progenitor cells in dengue

Tsai, J. J., Liu, L. T., Chang, K., Wang, S. H., Hsiao, H. M., Clark, K. B. & Perng, G-C., 2012 Jan 1, In : Therapeutic Advances in Hematology. 3, 1, p. 59-71 13 p.

Research output: Contribution to journalReview article

Dengue
Hematopoietic Stem Cells
Bone Marrow
Disease Progression
Patient Care
2010
37 Citations (Scopus)

Cells in dengue virus infection in vivo

Noisakran, S., Onlamoon, N., Songprakhon, P., Hsiao, H. M., Chokephaibulkit, K. & Perng, G. C., 2010 Dec 1, In : Advances in Virology. 2010, 164878.

Research output: Contribution to journalReview article

Severe Dengue
Dengue Virus
Virus Diseases
Dengue
Viremia
47 Citations (Scopus)

The role of insulin receptor signaling in synaptic plasticity and cognitive function

Huang, C. C., Lee, C. C. & Hsu, K. S., 2010 Mar 1, In : Chang Gung medical journal. 33, 2, p. 115-125 11 p.

Research output: Contribution to journalReview article

Neuronal Plasticity
Insulin Receptor
Cognition
Insulin
Brain
62 Citations (Scopus)

Towards an understanding of the herpes simplex virus type 1 latency-reactivation cycle

Jones, C. & Perng, G. C., 2010 Apr 22, In : Interdisciplinary Perspectives on Infectious Diseases. 2010, 262415.

Research output: Contribution to journalReview article

Virus Latency
Human Herpesvirus 1
Trigeminal Ganglion
Viral Genes
Peripheral Nervous System
2009
36 Citations (Scopus)

A re-evaluation of the mechanisms leading to dengue hemorrhagic fever

Noisakran, S., Chokephaibulkit, K., Songprakhon, P., Onlamoon, N., Hsiao, H. M., Villinger, F., Ansari, A. & Perng, G-C., 2009 Jan 1, In : Annals of the New York Academy of Sciences. 1171, SUPPL. 1

Research output: Contribution to journalReview article

Severe Dengue
Dengue Virus
Viruses
Dengue
Viremia
2007
15 Citations (Scopus)

Unravelling the neuropathogenesis of Japanese encephalitis

Myint, K. S. A., Gibbons, R. V., Perng, G-C. & Solomon, T., 2007 Oct 1, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 101, 10, p. 955-956 2 p.

Research output: Contribution to journalReview article

Japanese Encephalitis
Encephalitis
Blood-Brain Barrier
Brain Injuries
Survivors
2006
23 Citations (Scopus)

Pharmacological roles of the large-conductance calcium-activated potassium channel

Wu, S. N., Wu, A. Z. & Lin, M. W., 2006 May 1, In : Current Topics in Medicinal Chemistry. 6, 10, p. 1025-1030 6 p.

Research output: Contribution to journalReview article

Large-Conductance Calcium-Activated Potassium Channels
Pharmacology
Muscle
Acetogenins
Cells
2005
36 Citations (Scopus)

Do stress and long-term potentiation share the same molecular mechanisms?

Huang, C. C., Yang, C. H. & Hsu, K-S., 2005 Jan 1, In : Molecular Neurobiology. 32, 3, p. 223-235 13 p.

Research output: Contribution to journalReview article

Neuronal Plasticity
Long-Term Potentiation
Depression
Biological Factors
Cognition
2004
37 Citations (Scopus)

Cannabinoid-induced presynaptic inhibition at the primary afferent trigeminal synapse of juvenile rat brainstem slices

Liang, Y. C., Huang, C. C., Hsu, K-S. & Takahashi, T., 2004 Feb 15, In : Journal of Physiology. 555, 1, p. 85-96 12 p.

Research output: Contribution to journalReview article

Cannabinoids
Excitatory Postsynaptic Potentials
Synapses
Brain Stem
Cannabinoid Receptor CB1
29 Citations (Scopus)

The latency-related gene encoded by bovine herpesvirus 1 can suppress caspase 3 and caspase 9 cleavage during productive infection

Henderson, G., Perng, G-C., Nesburn, A. B., Wechsler, S. L. & Jones, C., 2004 Feb 1, In : Journal of NeuroVirology. 10, 1, p. 64-70 7 p.

Research output: Contribution to journalReview article

Bovine Herpesvirus 1
Caspase 9
Caspase 3
Infection
Genes
16 Citations (Scopus)

Therapeutic potential of cannabinoids in trigeminal neuralgia

Liang, Y. C., Huang, C. C. & Hsu, K-S., 2004 Dec 1, In : Current Drug Targets: CNS and Neurological Disorders. 3, 6, p. 507-514 8 p.

Research output: Contribution to journalReview article

Trigeminal Neuralgia
Cannabinoids
Pain
Neuralgia
Therapeutics
2003
96 Citations (Scopus)

Large-conductance Ca2+-activated K+ channels: Physiological role and pharmacology

Wu, S-N., 2003 Apr 1, In : Current Medicinal Chemistry. 10, 8, p. 649-661 13 p.

Research output: Contribution to journalReview article

Calcium-Activated Potassium Channels
Endothelial cells
Neuroendocrine Cells
Endothelial Cells
vinpocetine
2002
58 Citations (Scopus)

Alterations in the balance of protein kinase and phosphatase activities and age-related impairments of synaptic transmission and long-term potentiation

Hsu, K-S., Huang, C. C., Liang, Y. C., Wu, H. M., Chen, Y. L., Lo, S. W. & Ho, W. C., 2002 Dec 1, In : Hippocampus. 12, 6, p. 787-802 16 p.

Research output: Contribution to journalReview article

Long-Term Potentiation
Phosphoprotein Phosphatases
Synaptic Transmission
Protein Kinases
Avoidance Learning
60 Citations (Scopus)

Regulation of caspase 8- and caspase 9-induced apoptosis by the herpes simplex virus type 1 lantency-associated transcript

Henderson, G., Peng, W., Jin, L., Perng, G. C., Nesburn, A. B., Wechsler, S. L. & Jones, C., 2002 Dec 1, In : Journal of NeuroVirology. 8, SUPPL. 2, p. 103-111 9 p.

Research output: Contribution to journalReview article

Caspase 9
Caspase 8
Human Herpesvirus 1
Apoptosis
Caspases
17 Citations (Scopus)

Role for cAMP and protein phosphatase in the presynaptic expression of mouse hippocampal mossy fibre depotentiation

Huang, C. C., Chen, Y. L., Liang, Y. C. & Hsu, K-S., 2002 Sep 15, In : Journal of Physiology. 543, 3, p. 767-778 12 p.

Research output: Contribution to journalReview article

Hippocampal Mossy Fibers
Long-Term Synaptic Depression
Phosphoprotein Phosphatases
Metabotropic Glutamate Receptors
Long-Term Potentiation
2001
81 Citations (Scopus)

Progress in understanding the factors regulating reversibility of long-term potentiation

Huang, C. C. & Hsu, K-S., 2001 Jan 1, In : Reviews in the Neurosciences. 12, 1, p. 51-68 18 p.

Research output: Contribution to journalReview article

Long-Term Synaptic Depression
Long-Term Potentiation
Purinergic P1 Receptor Agonists
Phosphoprotein Phosphatases
N-Methyl-D-Aspartate Receptors