Organization profile

Organisation profile

Welcome to ICM, NCKU, the bridge between the gap between biomedical discovery and medical innovation. The remarkable pace of progress in biological knowledge resulting from the development of modern molecular and cell biology has made it harder for the biomedical community to incorporate this new information into medical practice. On the other hand, new fields of study, such as genomics and proteomics, have created fresh opportunities for understanding disease-related biology including cancer biology, immunology, neurobiology, stem cell biology and human metabolism. In order to translate the enormous academic achievement into applications for the treatment of disease, the faculty of at ICM, NCKU has worked tirelessly to facilitate translational medicine at many levels. The goal of this institute is to smooth the progress of understanding of human disease and thereby shorten the path to the bedside application. Through innovative research and course work, we offer academic degrees at master and PhD levels to qualified candidates, medical professionals and biological scientists alike, who are ready to develop their careers in translational medicine. Please come in and have a rewarding experience. Goals The Institute was established in August 1998. The graduate programs in the clinical medicine offers advanced research training courses of master and Ph.D. degree for the physicians and biomedical researchers. The major goals include: 1. To cultivated physician scientists (To cultivate physician scientists) 2. To solve the important clinical questions in Taiwan 3. To assist clinical research development in the University Hospital 4. To provide research service through core-laboratories Institution Highlights Our main research subjects include genetics, cancer, infectious diseases, neurology and cardiovascular diseases, and metabolism. The Institute of clinical Medicine and the Research Center are located on the 7th floor of the National Cheng Kung University Hospital. A variety of instruments are available within the institution for biomedical research and teaching. In addition to research education laboratory,we also have common instruments room, pure water room, cell culture room, photographic darkroom, isotope room, molecular medicine laboratory, flowcytometry, imaging and genetics core laboratory. Core Facility Ultra-Low Temperature Freezers, GeneAmp PCR system, inverted microscope, DNA sequencer, DNA synthesizer, Electrophoresis imager analyzer, Phosphorescence-Fluorescence analyzer, Chemiluminesence analyzer, Cryogenic Storage Systems, Ultracentrifuge, Genetic Analyzer, Slides Maker, Real-time PCR system, UV/Visible Spectorphotometer, Beta-counter, Gamma-counter, Pure Water System, Protein and DNA electrophoresis.

Fingerprint Dive into the research topics where Institute of Clinical Medicine is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Neoplasms Medicine & Life Sciences
Taiwan Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Lung Neoplasms Medicine & Life Sciences
Cells Chemical Compounds
Neoplasm Metastasis Medicine & Life Sciences
Genes Medicine & Life Sciences
gemcitabine Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2000 2021

Research Output 1986 2020

A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study

Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., 2020 Jan, In : European Journal of Cancer. 124, p. 123-130 8 p.

Research output: Contribution to journalArticle

oxaliplatin
gemcitabine
Leucovorin
Adenocarcinoma
irinotecan
1 Citation (Scopus)

4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin

Lin, M. S., Hong, T. M., Chou, T. H., Yang, S. C., Chung, W. C., Weng, C. W., Tsai, M. L., Cheng, T. J. R., Chen, J. J. W., Lee, T. C., Wong, C. H., Chein, R. J. & Yang, P. C., 2019 Nov 1, In : European Journal of Medicinal Chemistry. 181, 111584.

Research output: Contribution to journalArticle

4-Quinolones
Quinolones
Colchicine
Tubulin
Microtubules

A DNA Aptamer Targeting Galectin-1 as a Novel Immunotherapeutic Strategy for Lung Cancer

Tsai, Y. T., Liang, C. H., Yu, J. H., Huang, K. C., Tung, C. H., Wu, J. E., Wu, Y. Y., Chang, C. H., Hong, T. M. & Chen, Y. L., 2019 Dec 6, In : Molecular Therapy - Nucleic Acids. 18, p. 991-998 8 p.

Research output: Contribution to journalArticle

Open Access
Galectin 1
Nucleotide Aptamers
Lung Neoplasms
T-Lymphocytes
Neoplasms

Equipment

BD FACS Aria

Institute of Clinical Medicine

Facility/equipment: EquipmentClinical Medicine Research Center

Cells
Lasers

Bruker Autoflex III MALDI-TOF

Institute of Clinical Medicine

Facility/equipment: EquipmentClinical Medicine Research Center

Ionization
Desorption
Lasers
Molecules
Biomolecules

C-HTS

Kuen-Jer Tsai (Manager), 純瑜 郭 (Operator) & 廉筠 張 (Operator)

Instrument Development Center

Facility/equipment: EquipmentInstrument Development Center