Research Output 1986 2020

2020

A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study

Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., 2020 Jan, In : European Journal of Cancer. 124, p. 123-130 8 p.

Research output: Contribution to journalArticle

oxaliplatin
gemcitabine
Leucovorin
Adenocarcinoma
irinotecan
Open Access
neurons
Neurons
Current density
Chemical activation
Clamping devices

Effects of neural stem cell transplantation in Alzheimer's disease models

Hayashi, Y., Lin, H. T., Lee, C. C. & Tsai, K. J., 2020 Jan 27, In : Journal of biomedical science. 27, 1, 29.

Research output: Contribution to journalReview article

Open Access
Neural Stem Cells
Stem Cell Transplantation
Stem cells
Alzheimer Disease
Neurodegenerative diseases

High fat diet suppresses peroxisome proliferator-activated receptors and reduces dopaminergic neurons in the substantia nigra

Kao, Y. C., Wei, W. Y., Tsai, K. J. & Wang, L. C., 2020 Jan 1, In : International journal of molecular sciences. 21, 1, 207.

Research output: Contribution to journalArticle

Open Access
diets
Peroxisome Proliferator-Activated Receptors
Dopaminergic Neurons
fats
High Fat Diet

How mycobacteria take advantage of the weakness in human immune system in the modern world

Chao, W. C., Yen, C. L., Wu, C. H. & Shieh, C. C., 2020 Jan 1, (Accepted/In press) In : Journal of Microbiology, Immunology and Infection.

Research output: Contribution to journalReview article

Open Access
Mycobacterium
Immune System
Tuberculosis
Infection
Diabetes Mellitus

Il-20 in acute kidney injury: Role in pathogenesis and potential as a therapeutic target

Lin, T. Y. & Hsu, Y. H., 2020 Feb 1, In : International journal of molecular sciences. 21, 3, 1009.

Research output: Contribution to journalReview article

Open Access
kidney diseases
pathogenesis
kidneys
Acute Kidney Injury
Chronic Renal Insufficiency

Neuroinflammation and neurogenesis in alzheimer’s disease and potential therapeutic approaches

Sung, P. S., Lin, P. Y., Liu, C. H., Su, H. C. & Tsai, K. J., 2020 Feb 1, In : International journal of molecular sciences. 21, 3, 701.

Research output: Contribution to journalReview article

Open Access
Neurogenesis
Alzheimer Disease
Modulation
modulation
brain

The Impact of Antiplatelet Use on the Risk of Intracerebral Hemorrhage in Patients with Alzheimer's Disease: A Nationwide Cohort Study

Lee, T. L., Liu, C. H., Chang, Y. M., Lin, T. Y., Chien, C. Y., Chen, C. H., Tsai, K. J., Lin, S. H. & Sung, P. S., 2020 Jan 1, In : Journal of Alzheimer's Disease. 73, 1, p. 297-306 10 p.

Research output: Contribution to journalArticle

Cerebral Hemorrhage
Alzheimer Disease
Cohort Studies
Therapeutics
Propensity Score
2019
1 Citation (Scopus)

4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin

Lin, M. S., Hong, T. M., Chou, T. H., Yang, S. C., Chung, W. C., Weng, C. W., Tsai, M. L., Cheng, T. J. R., Chen, J. J. W., Lee, T. C., Wong, C. H., Chein, R. J. & Yang, P. C., 2019 Nov 1, In : European Journal of Medicinal Chemistry. 181, 111584.

Research output: Contribution to journalArticle

4-Quinolones
Quinolones
Colchicine
Tubulin
Microtubules

A DNA Aptamer Targeting Galectin-1 as a Novel Immunotherapeutic Strategy for Lung Cancer

Tsai, Y. T., Liang, C. H., Yu, J. H., Huang, K. C., Tung, C. H., Wu, J. E., Wu, Y. Y., Chang, C. H., Hong, T. M. & Chen, Y. L., 2019 Dec 6, In : Molecular Therapy - Nucleic Acids. 18, p. 991-998 8 p.

Research output: Contribution to journalArticle

Open Access
Galectin 1
Nucleotide Aptamers
Lung Neoplasms
T-Lymphocytes
Neoplasms

Alpha-1 adrenergic-antagonist use increases the risk of sleep apnea: A nationwide population-based cohort study

Su, P. L., Lin, W. K., Lin, C. Y. & Lin, S. H., 2019 Nov 15, In : Journal of Clinical Sleep Medicine. 15, 11, p. 1571-1579 9 p.

Research output: Contribution to journalArticle

Adrenergic alpha-1 Receptor Antagonists
Adrenergic Antagonists
Sleep Apnea Syndromes
Cohort Studies
Hypertension
Stomach Neoplasms
Liver
Robotics
Punctures
Lymph Node Excision
1 Citation (Scopus)

Bidirectional relationship between systemic lupus erythematosus and non-Hodgkin's lymphoma: A nationwide population-based study

Wang, L. H., Wang, W. M., Lin, S-H. & Shieh, C-C., 2019 Jul 1, In : Rheumatology (United Kingdom). 58, 7, p. 1245-1249 5 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Non-Hodgkin's Lymphoma
Population
Incidence
Taiwan

Bronchoscopy-guided bronchial epithelium sampling as a tool for selecting the optimal biologic treatment in a patient with severe asthma: A case report

Kuo, C. W., Liao, X. M., Huang, Y. C., Chang, H. Y. & Shieh, C. C., 2019 Nov 27, In : Allergy, Asthma and Clinical Immunology. 15, 1, 76.

Research output: Contribution to journalArticle

Open Access
Bronchoscopy
Asthma
Epithelium
Biological Products
Biological Factors
1 Citation (Scopus)
Open Access
Photosensitizing Agents
Membranes
Lighting
verteporfin
Dithiothreitol
1 Citation (Scopus)

Comparison of Home and Ambulatory Blood Pressure Measurements in Association With Preclinical Hypertensive Cardiovascular Damage

Lin, T. T., Juang, J. J. M., Lee, J. K., Tsai, C. T., Chen, C. H., Yu, W. C., Cheng, H. M., Wu, Y. W., Chiu, Y. W., Kuo, C. T., Chen, J. J., Chen, Z. C., Chang, W. T., Liu, P. Y., Chen, P. W., Yen, H. W., Chen, Y. C., Tseng, W. K., Chiang, F. T. & Wu, C. K., 2019 Mar 1, In : Journal of Cardiovascular Nursing. 34, 2, p. 106-114 9 p.

Research output: Contribution to journalArticle

Ambulatory Blood Pressure Monitoring
Blood Pressure
Pulse Wave Analysis
Hypertension
Prehypertension
5 Citations (Scopus)
ivabradine
Neurons
linopirdine
Endocrine Cells
Reducing Agents
Open Access
Inflammasomes
Clostridium difficile
Adenosine Triphosphate
Medicine
corrigendum
Postal Service
Taiwan
Nursing
Medicine
Neoplasms

Downregulated salt-inducible kinase 3 expression promotes chemoresistance in serous ovarian cancer via the ATP‐binding cassette protein ABCG2

Liang, Y. L., Wu, C. H., Kang, C. Y., Lin, C. N., Shih, N. Y., Lin, S. H., Chen, Y. C. & Hsu, K. F., 2019 Jan 1, In : Journal of Cancer. 10, 24, p. 6025-6036 12 p.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Phosphotransferases
Down-Regulation
Salts
ATP Binding Cassette Transporter, Sub-Family G, Member 2
1 Citation (Scopus)
Open Access
pioglitazone
Diet
Hepatic Stellate Cells
Insulin Resistance
Autophagy
Open Access
Galectin 3
rho-Associated Kinases
Medical problems
Platelets
Protein Kinases

Enhanced risk of traumatic brain injury in patients with chronic obstructive pulmonary disease

Huang, T. H., Chen, C. Z., Kuo, H. I., Er, H. P. & Lin, S. H., 2019 Jan 1, (Accepted/In press) In : Journal of Investigative Medicine.

Research output: Contribution to journalArticle

Open Access
Pulmonary diseases
Chronic Obstructive Pulmonary Disease
Brain
Obstructive Lung Diseases
Propensity Score
Ficus
Gastrointestinal Stromal Tumors
Sequence Deletion
Codon
Exons

Erythropoietin prevents dementia in hemodialysis patients: A nationwide population-based study

Hung, P. H., Yeh, C. C., Sung, F. C., Hsiao, C. Y., Muo, C. H., Hung, K. Y. & Tsai, K. J., 2019 Sep 1, In : Aging. 11, 17, p. 6941-6950 10 p.

Research output: Contribution to journalArticle

Erythropoietin
Dementia
Renal Dialysis
Population
Vascular Dementia

Exercise alleviates osteoporosis in rats with mild chronic kidney disease by decreasing sclerostin production

Liao, H. W., Huang, T. H., Chang, Y. H., Liou, H. H., Chou, Y. H., Sue, Y. M., Hung, P. H., Chang, Y. T., Ho, P. C. & Tsai, K. J., 2019 Apr 2, In : International journal of molecular sciences. 20, 8, 2044.

Research output: Contribution to journalArticle

Open Access
kidney diseases
osteoporosis
physical exercise
Chronic Renal Insufficiency
bones

Experience of applying cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian teratoma with malignant transformation and peritoneal dissemination

Yu, H. H., Yonemura, Y., Hsieh, M. C., Lu, C. Y., Wu, S. Y. & Shan, Y. S., 2019 Jan 1, In : Therapeutics and Clinical Risk Management. 15, p. 129-136 8 p.

Research output: Contribution to journalArticle

Open Access
Chemotherapy
Teratoma
Surgery
surgery
Drug Therapy
1 Citation (Scopus)

Gastroesophageal reflux disease and atrial fibrillation: Insight from autonomic cardiogastric neural interaction

Huang, T. C., Lo, L. W., Yamada, S., Chou, Y. H., Lin, W. L., Chang, S. L., Lin, Y. J., Liu, S. H., Cheng, W. H., Tsai, T. Y., Liu, P. Y. & Chen, S. A., 2019 Nov 1, In : Journal of Cardiovascular Electrophysiology. 30, 11, p. 2262-2270 9 p.

Research output: Contribution to journalArticle

Gastroesophageal Reflux
Atrial Fibrillation
Electrophysiology
Acids
Muscarinic Antagonists

Group A Streptococcus Subcutaneous Infection-Induced Central Nervous System Inflammation Is Attenuated by Blocking Peripheral TNF

Liu, Y., Wu, P., Kang, C., Tsai, Y., Chou, C., Liang, C., Wu, J. & Tsai, P., 2019, In : Frontiers in Microbiology. 10

Research output: Contribution to journalArticle

High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma

Lin, C. H., Li, H. Y., Liu, Y. P., Kuo, P. F., Wang, W. C., Lin, F. C., Chang, W. L., Sheu, B. S., Wang, Y. C., Hung, W. C., Cheng, H. C., Yao, Y. C., Calkins, M. J., Hsiao, M. & Lu, P. J., 2019 Jan 1, In : Therapeutic Advances in Medical Oncology. 11

Research output: Contribution to journalArticle

Open Access
Stem Cells
Fursultiamin
Neoplasms
Therapeutics
Neoplastic Stem Cells

High effectiveness in actions of carfilzomib on delayed-rectifier K+ current and on spontaneous action potentials

So, E. C., Liu, P. Y., Lee, C. C. & Wu, S. N., 2019 Jan 1, In : Frontiers in Pharmacology. 10, 1163.

Research output: Contribution to journalArticle

Open Access
Action Potentials
Vascular Smooth Muscle
Smooth Muscle Myocytes
Neuroendocrine Cells
Proteasome Inhibitors
3 Citations (Scopus)

Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology

Hung, P. F., Hong, T. M., Chang, C. C., Hung, C. L., Hsu, Y. L., Chang, Y. L., Wu, C. T., Chang, G. C., Chan, N. L., Yu, S. L., Yang, P. C. & Pan, S. H., 2019 Jan 6, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 5.

Research output: Contribution to journalArticle

Open Access
Sumoylation
Gastropoda
Biological Science Disciplines
Biochemistry
Cell Biology

IL-29 promoted obesity-induced inflammation and insulin resistance

Lin, T. Y., Chiu, C. J., Kuan, C. H., Chen, F. H., Shen, Y. C., Wu, C-H. & Hsu, Y-H., 2019 Jan 1, In : Cellular and Molecular Immunology.

Research output: Contribution to journalArticle

Interleukins
Insulin Resistance
Obesity
Inflammation
Macrophages

Impact of platelet volume on the clinical outcomes of patients with acute coronary syndrome

Chang, H. Y., Hsu, L. W., Lee, C. H., Lin, C. C., Huang, C. W., Chen, P. W., Yang, P. K., Hsueh, Y. C. & Liu, P. Y., 2019 Jan 1, In : Acta Cardiologica Sinica. 35, 6, p. 563-570 8 p.

Research output: Contribution to journalArticle

Mean Platelet Volume
Acute Coronary Syndrome
Blood Platelets
clopidogrel
Platelet Aggregation Inhibitors
Open Access
cardiac arrest
rating scales
Heart Arrest
Retrospective Studies
Emergency rooms
1 Citation (Scopus)
Aplastic Anemia
Databases
Incidence
Population
Survival

Increased ILC3s associated with higher levels of IL‐1β aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase

Chan, T., Yen, C., Huang, Y., Lo, P., Nigrovic, P. A., Cheng, C., Wang, W., Wu, S. & Shieh, C-C., 2019 Jul 26, In : European Journal of Immunology.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer

Weng, C. C., Hsieh, M. J., Wu, C. C., Lin, Y. C., Shan, Y. S., Hung, W. C., Chen, L. T. & Cheng, K. H., 2019 May 20, In : Molecular cancer. 18, 1, 96.

Research output: Contribution to journalArticle

Open Access
Pancreatic Neoplasms
Adenocarcinoma
Epithelial-Mesenchymal Transition
Neoplasm Metastasis
Epigenomics
4 Citations (Scopus)
Open Access
Death Domain Receptors
Neoplastic Stem Cells
Pancreatic Neoplasms
Ligands
T-Lymphocytes

Male patients on peritoneal dialysis have a higher risk of sleep apnea

Lee, Y. C., Hung, S. Y., Wang, H. K., Lin, C. W., Wang, H. H., Chang, M. Y., Wu, C. F., Sung, J. M., Chiou, Y. Y. & Lin, S. H., 2019 Jan 1, In : Journal of Clinical Sleep Medicine. 15, 7, p. 937-945 9 p.

Research output: Contribution to journalArticle

Sleep Apnea Syndromes
Peritoneal Dialysis
Renal Dialysis
Uremia
Databases

MicroRNA-150-5p promotes cell motility by inhibiting c-Myb-mediated Slug suppression and is a prognostic biomarker for recurrent ovarian cancer

Tung, C. H., Kuo, L. W., Huang, M. F., Wu, Y. Y., Tsai, Y. T., Wu, J. E., Hsu, K. F., Chen, Y. L. & Hong, T. M., 2019 Jan 1, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Gastropoda
MicroRNAs
Ovarian Neoplasms
Cell Movement
Biomarkers

Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors

Hsueh, Y. S., Chang, H. H., Shan, Y. S., Sun, H. S., Fletcher, J. A., Li, C. F. & Chen, L. T., 2019 Sep 19, In : Oncogene. 38, 38, p. 6550-6565 16 p.

Research output: Contribution to journalArticle

Open Access
Gastrointestinal Stromal Tumors
Stromal Cells
Chromatin Immunoprecipitation
Valproic Acid
Carcinogenesis

Pancreatic stellate cells activated by mutant KRAS-mediated PAI-1 upregulation foster pancreatic cancer progression via IL-8

Wang, H. C., Lin, Y. L., Hsu, C. C., Chao, Y. J., Hou, Y. C., Chiu, T. J., Huang, P. H., Tang, M. J., Chen, L. T. & Shan, Y. S., 2019 Jan 1, In : Theranostics. 9, 24, p. 7168-7183 16 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Stellate Cells
Plasminogen Activator Inhibitor 1
Interleukin-8
Pancreatic Neoplasms
Up-Regulation
1 Citation (Scopus)

Postoperative Mycobacteroides abscessus subsp. abscessus endophthalmitis: Clinical analysis of 12 clustered adults and a proposed therapeutic algorithm

Hung, J-H., Ko, W-C., Chen, C. Y., Lin, S-H., Wu, C. L., Hsu, S-M., Teng, Y. T., Wang, S. H., Tseng, S. H., Huang, F-C., Lai, C. C., Chen, C. L., Lai, C. H., Chen, P-L. & Jou-Chen Huang, E., 2019 Jan 1, (Accepted/In press) In : Journal of Microbiology, Immunology and Infection.

Research output: Contribution to journalArticle

Endophthalmitis
Temazepam
Vitrectomy
Taiwan
Nontuberculous Mycobacteria

Postpartum deep vein thrombosis resolved by catheter-directed thrombolysis: A case report

Chen, P. W. & Liu, P. Y., 2019 Jun 1, In : Medicine (United States). 98, 24, e16052.

Research output: Contribution to journalArticle

Open Access
Venous Thrombosis
Postpartum Period
Catheters
Iliac Vein
Femoral Vein
5 Citations (Scopus)

Protein arginine methyltransferase 3 enhances chemoresistance in pancreatic cancer by methylating hnRNPA1 to increase ABCG2 expression

Hsu, M. C., Pan, M. R., Chu, P. Y., Tsai, Y. L., Tsai, C. H., Shan, Y. S., Chen, L. T. & Hung, W. C., 2019 Jan 1, In : Cancers. 11, 1, 8.

Research output: Contribution to journalArticle

Open Access
Protein-Arginine N-Methyltransferases
Pancreatic Neoplasms
gemcitabine
Adenosine Triphosphate
Drug Resistance

Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer

Hsu, M. C., Tsai, Y. L., Lin, C. H., Pan, M. R., Shan, Y-S., Cheng, T. Y., Cheng, S. H. C., Chen, L. T. & Hung, W. C., 2019 Jul 19, In : Journal of Hematology and Oncology. 12, 1, 79.

Research output: Contribution to journalArticle

Open Access
Protein-Arginine N-Methyltransferases
Glyceraldehyde-3-Phosphate Dehydrogenases
Pancreatic Neoplasms
Respiration
Oxidative Phosphorylation

Regeneration of rete ridges in Lanyu pig (Sus scrofa): Insights for human skin wound healing

Lin, C. H., Chiu, P. Y., Hsueh, Y-Y., Shieh, S-J., Wu, C-C., Wong, T-W., Chuong, C. M. & Hughes, M. W., 2019 Apr 1, In : Experimental Dermatology. 28, 4, p. 472-479 8 p.

Research output: Contribution to journalArticle

Sus scrofa
Proliferating Cell Nuclear Antigen
Wound Healing
Alkaline Phosphatase
Regeneration
1 Citation (Scopus)
Metaplasia
Helicobacter pylori
Stomach Neoplasms
MicroRNAs
spasmolytic polypeptide

Subsequent thyroid disorders associated with treatment strategy in head and neck cancer patients: A nationwide cohort study

Lin, C. L., Wu, S. Y., Huang, W. T., Feng, Y. H., Yiu, C. Y., Chiang, W. F., Ho, S. Y. & Lin, S. H., 2019 May 16, In : BMC cancer. 19, 1, 461.

Research output: Contribution to journalArticle

Open Access
Head and Neck Neoplasms
Thyroid Gland
Cohort Studies
Radiotherapy
Neoplasms