Institute of Clinical Pharmacy and Pharmaceutical Sciences

Research Output 1991 2019

2019

Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population

Zheng, C. M., Wang, J. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Chiu, S. P., Chang, T. J., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M-C., Hsu, Y. H. & 4 others, Chiou, H. Y., Kao, S., Wu, M. Y. & Lin, Y. F., 2019 Dec 1, In : Scientific reports. 9, 1, 2694.

Research output: Contribution to journalArticle

Open Access
Angiotensin Receptor Antagonists
Chronic Renal Insufficiency
Angiotensin-Converting Enzyme Inhibitors
Angiotensins
Kidney
1 Citation (Scopus)

Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure

Taylor, P., Yan-Jye, S., Momper, J., Hou, W., Camacho-Hernandez, G. A., Radic', Z., Rosenberg, Y., Kovarik, Z., Sit, R. & Sharpless, K. B., 2019 Aug 1, In : Chemico-Biological Interactions. 308, p. 194-197 4 p.

Research output: Contribution to journalReview article

Antidotes
Oximes
Organophosphates
Acetylcholinesterase
Fasciculation
2 Citations (Scopus)
Open Access
ovaries
Polycystic Ovary Syndrome
Metformin
polymorphism
Polymorphism

Bioassay-guided purification of sesquiterpenoids from the fruiting bodies of: Fomitopsis pinicola and their anti-inflammatory activity

Tai, S. H., Kuo, P. C., Hung, C. C., Lin, Y. H., Hwang, T. L., Lam, S. H., Kuo, D. H., Wu, J. B., Hung, H. Y. & Wu, T. S., 2019 Jan 1, In : RSC Advances. 9, 59, p. 34184-34195 12 p.

Research output: Contribution to journalArticle

Open Access
Bioassay
Fungi
Purification
Anti-Inflammatory Agents
Negative ions

Budget impact analysis of osteoporosis medications for primary prevention of fractures in Taiwan

Wu, K. L., Wu, C. H., Chang, Y. F., Lin, Y. T. & Hsu, J. C., 2019 Jan 1, (Accepted/In press) In : Journal of Bone and Mineral Metabolism.

Research output: Contribution to journalArticle

Budgets
Primary Prevention
Taiwan
Osteoporosis
Costs and Cost Analysis

By protecting against cutaneous inflammation, epidermal pigmentation provided an additional advantage for ancestral humans

Lin, T. K., Man, M. Q., Abuabara, K., Wakefield, J. S., Sheu, H. M., Tsai, J. C., Lee, C. H. & Elias, P. M., 2019 Dec 1, In : Evolutionary Applications. 12, 10, p. 1960-1970 11 p.

Research output: Contribution to journalArticle

Open Access
Pigmentation
pigmentation
skin
inflammation
Inflammation
Open Access
Orchidaceae
Phalaenopsis
flavone
extracts
flavones
7 Citations (Scopus)

Detecting potential adverse drug reactions using a deep neural network model

Wang, C. S., Lin, P. J., Cheng, C-L., Tai, S. H., Kao, Y-H. & Chiang, J-H., 2019 Feb 1, In : Journal of medical Internet research. 21, 2, e11016.

Research output: Contribution to journalArticle

Neural Networks (Computer)
Drug-Related Side Effects and Adverse Reactions
Pharmaceutical Preparations
Pharmacovigilance
ROC Curve
1 Citation (Scopus)
Propensity Score
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Cohort Studies
Confidence Intervals

Health-related quality of life associated with different cancer treatments in Chinese breast cancer survivors in Taiwan

Ou, H. T., Chung, W. P., Su, P. F., Lin, T. H., Lin, J. Y., Wen, Y. C. & Fang, W. T., 2019 Jul, In : European Journal of Cancer Care. 28, 4, e13069.

Research output: Contribution to journalArticle

Taiwan
Survivors
Quality of Life
Breast Neoplasms
Neoplasms
Open Access
Fertilization in Vitro
Pregnancy Outcome
Longitudinal Studies
Cohort Studies
Quality of Life

Semiparametric additive rates model for recurrent events data with intermittent gaps

Su, P-F., Zhong, J. & Ou, H-T., 2019 Apr 15, In : Statistics in Medicine. 38, 8, p. 1343-1356 14 p.

Research output: Contribution to journalArticle

Recurrent Events
National Health Programs
Biased Estimation
Taiwan
Hypoglycemia
Open Access
Peritoneal Dialysis
Bone Density
Cross-Sectional Studies
Serum
Chronic Kidney Disease-Mineral and Bone Disorder
4 Citations (Scopus)
Thrombomodulin
Hydrogels
Hydrogel
Hyaluronic Acid
Gelatin
2018
4 Citations (Scopus)

A feasible and practical 1H NMR analytical method for the quality control and quantification of bioactive principles in Lycii Fructus

Hsieh, L. Y., Chan, H. H., Kuo, P. C., Hung, H. Y., Li, Y. C., Kuo, C. L., Peng, Y., Zhao, Z. Z., Kuo, D. H., Sun, I. W. & Wu, T. S., 2018 Jul, In : Journal of Food and Drug Analysis. 26, 3, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

Quality Control
quality control
analytical methods
Betaine
betaine

Calcium phosphate particles stimulate exosome secretion from phagocytes for the enhancement of drug delivery

Shyong, Y. J., Chang, K. C. & Lin, F. H., 2018 Nov 1, In : Colloids and Surfaces B: Biointerfaces. 171, p. 391-397 7 p.

Research output: Contribution to journalArticle

Exosomes
secretions
calcium phosphates
Calcium phosphate
Phagocytes
14 Citations (Scopus)
clopidogrel
Taiwan
Myocardial Infarction
Hemorrhage
Safety
4 Citations (Scopus)

Characterization of CRISPR-Cas systems in clinical Klebsiella pneumoniae isolates uncovers its potential association with antibiotic susceptibility

Li, H. Y., Kao, C. Y., Lin, W. H., Zheng, P. X., Yan, J. J., Wang, M. C., Teng, C. H., Tseng, C. C. & Wu, J. J., 2018 Jul 16, In : Frontiers in Microbiology. 9, JUL, 1595.

Research output: Contribution to journalArticle

CRISPR-Cas Systems
Klebsiella pneumoniae
Anti-Bacterial Agents
Genome
Microbial Drug Resistance
Peritoneal Dialysis
Peritonitis
Taiwan
Escherichia coli
Treatment Failure
Long-Acting Insulin
Insulins
Diabetes Complications
Type 1 Diabetes Mellitus
Taiwan
3 Citations (Scopus)
Dipeptidyl-Peptidase IV Inhibitors
Type 2 Diabetes Mellitus
Cohort Studies
Population
Confidence Intervals
Polycystic Ovary Syndrome
Metformin
Quality of Life
Health

Heart rate variability among women undergoing in vitro fertilization treatment: Its predictive ability for pregnancy

Wu, M-H., Su, P-F., Chen, K. Y., Tie, T. H., Ke, H. C., Chen, H., Su, Y. C., Su, Y. C. & Ou, H-T., 2018 Mar 1, In : PloS one. 13, 3, e0193899.

Research output: Contribution to journalArticle

in vitro fertilization
Fertilization in Vitro
heart rate
Heart Rate
pregnancy
13 Citations (Scopus)

Lower risk of dementia with pioglitazone, compared with other second-line treatments, in metformin-based dual therapy: a population-based longitudinal study

Lu, C. H., Yang, C. Y., Li, C. Y., Hsieh, C. Y. & Ou, H. T., 2018 Mar 1, In : Diabetologia. 61, 3, p. 562-573 12 p.

Research output: Contribution to journalArticle

pioglitazone
Metformin
Longitudinal Studies
Dementia
Population
11 Citations (Scopus)

Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress

Lin, Y. W., Chen, T. Y., Hung, C. Y., Tai, S. H., Huang, S. Y., Chang, C. C., Hung, H. Y. & Lee, E. J., 2018 Jul, In : International journal of molecular medicine. 42, 1, p. 182-192 11 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Melatonin
Reperfusion Injury
Brain Ischemia
Eukaryotic Initiation Factor-2
1 Citation (Scopus)

Pay for performance program reduces treatment needed diabetic retinopathy - A nationwide matched cohort study in Taiwan

Sheu, S. J., Lin, W. L., Kao, Y-H., Hwu, C. M. & Cheng, C-L., 2018 Aug 15, In : BMC Health Services Research. 18, 1, 638.

Research output: Contribution to journalArticle

Incentive Reimbursement
Diabetic Retinopathy
Taiwan
Cohort Studies
Therapeutics
7 Citations (Scopus)

Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques

Rosenberg, Y. J., Wang, J., Ooms, T., Rajendran, N., Mao, L., Jiang, X., Lees, J., Urban, L., Momper, J. D., Sepulveda, Y., Shyong, Y-J. & Taylor, P., 2018 Sep 1, In : Toxicology Letters. 293, p. 229-234 6 p.

Research output: Contribution to journalArticle

Paraoxon
Oximes
Macaca
Acetylcholinesterase
Insecticides
1 Citation (Scopus)

Relationship between body mass index and renal function deterioration among the Taiwanese chronic kidney disease population

Chang, T. J., Zheng, C. M., Wu, M. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M. C., Hsu, Y. H., Chiou, H. Y. & 2 others, Kao, S. & Lin, Y. F., 2018 Dec 1, In : Scientific reports. 8, 1, 6908.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Body Mass Index
Kidney
Population
Thinness
1 Citation (Scopus)
Escherichia coli Infections
Cytokines
Kidney
Urinary Bladder
Infection
1 Citation (Scopus)

The constituents of the stems of cissus assamica and their bioactivities

Chan, Y. Y., Wang, C. Y., Hwang, T. L., Juang, S. H., Hung, H. Y., Kuo, P. C., Chen, P. J. & Wu, T. S., 2018 Oct 28, In : Molecules. 23, 11, 23112799.

Research output: Contribution to journalArticle

Cissus
Bioactivity
stems
Inhibitory Concentration 50
acids
11 Citations (Scopus)

Validation of the 5-item medication adherence report scale in older stroke patients in Iran

Lin, C. Y., Ou, H. T., Nikoobakht, M., Broström, A., Årestedt, K. & Pakpour, A. H., 2018 Nov 1, In : Journal of Cardiovascular Nursing. 33, 6, p. 536-543 8 p.

Research output: Contribution to journalArticle

Medication Adherence
Iran
Stroke
Psychometrics
Health Personnel
2017
12 Citations (Scopus)

10-year trends in statin utilization in Taiwan: A retrospective study using Taiwan's National Health Insurance Research Database

Hsieh, H. C., Hsu, J. C. & Lu, C. Y., 2017 May 1, In : BMJ open. 7, 5, e014150.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
National Health Programs
Taiwan
Retrospective Studies
Databases
9 Citations (Scopus)
Dipeptidyl-Peptidase IV Inhibitors
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Heart Failure
Metformin
1 Citation (Scopus)
scoparone
fruits
Citrus
inorganic peroxides
Pancreatic Elastase
6 Citations (Scopus)
Quality of Life
Statistical Factor Analysis
Aptitude
Taiwan
Psychometrics
4 Citations (Scopus)
Polycystic Ovary Syndrome
Metformin
Insulin Resistance
Insulin
Sensitivity and Specificity
3 Citations (Scopus)

Effects of chronic hepatitis C infection on arterial stiffness

Chou, C. H., Ho, C. S., Tsai, W-C., Wang, M-C., Tsai, Y-S. & Chen, Z-Y., 2017 Nov 1, In : Journal of the American Society of Hypertension. 11, 11, p. 716-723 8 p.

Research output: Contribution to journalArticle

Vascular Stiffness
Chronic Hepatitis C
Hepacivirus
Virus Diseases
Infection

Effects of sebum on drug transport across the human stratum corneum

Tsai, J-C., Lan, C. C. E. & Sheu, H. M., 2017 Apr 28, Agache's Measuring the Skin: Non-invasive Investigations, Physiology, Normal Constants: Second Edition. Springer International Publishing, p. 389-395 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sebum
Cornea
Pharmaceutical Preparations
3 Citations (Scopus)

Endoplasmic reticulum stress-triggered autophagy and lysosomal dysfunction contribute to the cytotoxicity of amine-modified silver nanoparticles in NIH 3T3 cells

Lee, Y-H., Fang, C. Y., Chiu, H. W., Cheng, F. Y., Tsai, J-C., Chen, C. W. & Wang, Y-J., 2017 Jul 1, In : Journal of Biomedical Nanotechnology. 13, 7, p. 778-794 17 p.

Research output: Contribution to journalArticle

NIH 3T3 Cells
Endoplasmic Reticulum Stress
Autophagy
Biological systems
Cytotoxicity
5 Citations (Scopus)
Diabetes Complications
Type 1 Diabetes Mellitus
Taiwan
Diabetic Ketoacidosis
Longitudinal Studies
7 Citations (Scopus)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Longitudinal Studies
Cohort Studies
Cardiovascular Diseases
HIV
5 Citations (Scopus)
leisure time
health status
Taiwan
quality of life
Group
8 Citations (Scopus)

Mesoporous hydroxyapatite as a carrier of olanzapine for long-acting antidepression treatment in rats with induced depression

Shyong, Y-J., Wang, M. H., Kuo, L. W., Su, C. F., Kuo, W. T., Chang, K. C. & Lin, F. H., 2017 Jun 10, In : Journal of Controlled Release. 255, p. 62-72 11 p.

Research output: Contribution to journalArticle

olanzapine
Durapatite
Aptitude
Locomotion
Depression
5 Citations (Scopus)

Mortality prediction using CHADS2 /CHA2 DS2 -VASc/R2 CHADS2 scores in systolic heart failure patients with or without atrial fibrillation

Chen, Y. L., Cheng, C. L., Huang, J. L., Yang, N. I., Chang, H. C., Chang, K. C., Sung, S. H., Shyu, K. G., Wang, C. C., Yin, W. H., Lin, J. L. & Chen, S. M., 2017 Oct 1, In : Medicine (United States). 96, 43, e8338.

Research output: Contribution to journalArticle

Systolic Heart Failure
Atrial Fibrillation
Mortality
Taiwan
Cardiology
5 Citations (Scopus)

Pharmacoeconomic analysis of antifungal therapy for primary treatment of invasive candidiasis caused by Candida albicans and non-albicans Candida species

Ou, H-T., Lee, T. Y., Chen, Y. C. & Charbonneau, C., 2017 Jul 10, In : BMC Infectious Diseases. 17, 1, 481.

Research output: Contribution to journalArticle

Invasive Candidiasis
Echinocandins
Pharmaceutical Economics
Candida albicans
Candida
14 Citations (Scopus)

Recent trends in the use of antidiabetic medications from 2008 to 2013: A nation-wide population-based study from Taiwan

Ou, H-T., Chang, K. C., Liu, Y. & Wu, J-S., 2017 Mar 1, In : Journal of Diabetes. 9, 3, p. 256-266 11 p.

Research output: Contribution to journalArticle

Taiwan
Hypoglycemic Agents
Dipeptidyl-Peptidase IV Inhibitors
Population
Delivery of Health Care
9 Citations (Scopus)

Renoprotective Effect of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers in Diabetic Patients with Proteinuria

Hsu, F. Y., Lin, F. J., Ou, H-T., Huang, S. H. & Wang, C. C., 2017 Jun 1, In : Kidney and Blood Pressure Research. 42, 2, p. 358-368 11 p.

Research output: Contribution to journalArticle

Angiotensin Receptor Antagonists
Proteinuria
Angiotensin-Converting Enzyme Inhibitors
irbesartan
Kidney

Risks of newly onset hemorrhagic stroke in patients with neovascular age-related macular degeneration

Lee, W. J. A., Cheng, C-L., Lee, C-H., Kao, Y-H., Lin, S. J. & Hsieh, C. Y., 2017 Oct 1, In : Pharmacoepidemiology and drug safety. 26, 10, p. 1277-1285 9 p.

Research output: Contribution to journalArticle

Macular Degeneration
Stroke
International Classification of Diseases
Myocardial Infarction
Mortality
1 Citation (Scopus)

rs2841277 (PLD4) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis

Chen, W. C., Wang, W. C., Lu, H. F., Okada, Y., Chang, W. P., Chou, Y. H., Chang, H. H., Huang, J. D., Chen, D. Y. & Chang, W. C., 2017 Jan 1, In : Oncotarget. 8, 38, p. 64180-64190 11 p.

Research output: Contribution to journalArticle

Phospholipase D
Rheumatoid Arthritis
Ankylosing Spondylitis
Single Nucleotide Polymorphism
Genome-Wide Association Study