Research Output 1989 2019

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2019
8 Citations (Scopus)

Assessment of zero-valent iron-based nanotherapeutics for ferroptosis induction and resensitization strategy in cancer cells

Huang, K. J., Wei, Y. H., Chiu, Y. C., Wu, S. R. & Shieh, D. B., 2019 Apr, In : Biomaterials Science. 7, 4, p. 1311-1322 12 p.

Research output: Contribution to journalArticle

Medical nanotechnology
Iron
Cells
Glutathione Peroxidase
Nanoparticles
1 Citation (Scopus)

Dental cement's biological and mechanical properties improved by ZnO nanospheres

Nguyen, T. M. T., Wang, P. W., Hsu, H. M., Cheng, F. Y., Shieh, D. B., Wang, D-Y. & Chang, H. J., 2019 Apr 1, In : Materials Science and Engineering C. 97, p. 116-123 8 p.

Research output: Contribution to journalArticle

Dental cement
Dental Cements
Zinc Oxide
Nanospheres
cements

Effects of pontic span and fiber reinforcement on fracture strength of multi-unit provisional fixed partial dentures

Chang, M. C., Hung, C. C., Chen, W. C., Tseng, S. C., Chen, Y. C. & Wang, J. C., 2019 Sep, In : Journal of Dental Sciences. 14, 3, p. 309-317 9 p.

Research output: Contribution to journalArticle

Open Access
Fixed Partial Denture
Polymethyl Methacrylate
Fatigue
Analysis of Variance
Open Access
Silicon Dioxide
therapy
Iron
cancer
Silica
3 Citations (Scopus)

Molecular damage and responses of oral keratinocyte to hydrogen peroxide

Lin, K. Y., Chung, C. H., Ciou, J. S., Su, P. F., Wang, P. W., Shieh, D. B. & Wang, T. C., 2019 Jan 11, In : BMC Oral Health. 19, 1, 10.

Research output: Contribution to journalArticle

Keratinocytes
Hydrogen Peroxide
Dentin Sensitivity
Tooth Bleaching
Comet Assay

Prosthetic Correction of Proclined Maxillary Incisors: A Biomechanical Analysis

He, Y., Chen, Y. C., Teng, W., Fok, A. S. L. & Chew, H. P., 2019 Jan 1, In : Computational and Mathematical Methods in Medicine. 2019, 7416076.

Research output: Contribution to journalArticle

Open Access
Incisor
Prosthetics
Bone
Bone and Bones
Tooth

Targeted delivery of curcumin rescues endoplasmic reticulum-retained mutant Nox2 protein and avoids leukocyte apoptosis

Yen, C. L., Liao, Y. C., Chen, R. F., Huang, Y. F., Chung, W. C., Lo, P. C., Chang, C. F., Wu, P. C., Shieh, D. B., Jiang, S. T. & Shieh, C. C., 2019 Jun 15, In : Journal of Immunology. 202, 12, p. 3394-3403 10 p.

Research output: Contribution to journalArticle

Curcumin
Mutant Proteins
Endoplasmic Reticulum
Leukocytes
Apoptosis

The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance

Asare-Werehene, M., Nakka, K., Reunov, A., Chiu, C. T., Lee, W. T., Abedini, M. R., Wang, P. W., Shieh, D. B., Dilworth, F. J., Carmona, E., Le, T., Mes-Masson, A. M., Burger, D. & Tsang, B. K., 2019 Jan 1, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Gelsolin
Exosomes
Ovarian Neoplasms
Recurrence
Survival
2018
4 Citations (Scopus)

Characterization of iron core-gold shell nanoparticles for anti-cancer treatments: Chemical and structural transformations during storage and use

Wu, Y. N., Shieh, D. B., Yang, L. X., Sheu, H. S., Zheng, R., Thordarson, P., Chen, D. H. & Braet, F., 2018 Dec 17, In : Materials. 11, 12, 2572.

Research output: Contribution to journalArticle

Oncology
Gold
Iron
Nanoparticles
Cells

Comparison between two post-dentin bond strength measurement methods

Zhu, L., Li, Y., Chen, Y. C., Carrera, C. A., Wu, C. & Fok, A., 2018 Dec 1, In : Scientific reports. 8, 1, 2350.

Research output: Contribution to journalArticle

Friction
Finite element method
5 Citations (Scopus)

Enhancing enterovirus A71 vaccine production yield by microcarrier profusion bioreactor culture

Liu, C. C., Wu, S. C., Wu, S. R., Lin, H. Y., Guo, M. S., Yung-Chih Hu, A., Chow, Y. H., Chiang, J. R., Shieh, D. B. & Chong, P., 2018 May 24, In : Vaccine. 36, 22, p. 3134-3139 6 p.

Research output: Contribution to journalArticle

Enterovirus
Bioreactors
bioreactors
Vaccines
vaccines

In vitro properties for bioceramics composed of silica and titanium oxide composites

Chen, I. H., Lian, M. J., Fang, W., Huang, B. R., Liu, T. H., Chen, J. A., Huang, C. L. & Lee, T. M., 2018 Dec 25, In : Applied Sciences (Switzerland). 9, 1, 66.

Research output: Contribution to journalArticle

Bioceramics
Titanium oxides
titanium oxides
Silicon Dioxide
bones
1 Citation (Scopus)

Phosphophoryn and dentin sialoprotein effects on dental pulp cell migration, proliferation, and differentiation

Chuang, S. F., Chen, Y. H., Ma, P. & Ritchie, H. H., 2018 Dec, In : Dentistry Journal. 6, 4, 70.

Research output: Contribution to journalArticle

Open Access
Dental Pulp
Cell Movement
Cell Differentiation
Cell Proliferation
phosphophoryn

The effect of plasma treatment on the osseointegration of rough titanium implant: A histo-morphometric study in rabbits

Chou, W. C., Wang, R. C. C., Huang, C. L. & Lee, T. M., 2018 Sep 1, In : Journal of Dental Sciences. 13, 3, p. 267-273 7 p.

Research output: Contribution to journalArticle

Osseointegration
Titanium
Rabbits
Bone and Bones
Hydrophobic and Hydrophilic Interactions
2017
6 Citations (Scopus)

A disease model of muscle necrosis caused by aeromonas dhakensis infection in caenorhabditis elegans

Chen, P. L., Chen, Y. W., Ou, C. C., Lee, T. M., Wu, C. J., Ko, W. C. & Chen, C. S., 2017 Jan 4, In : Frontiers in Microbiology. 7, JAN, 2058.

Research output: Contribution to journalArticle

Aeromonas
Caenorhabditis elegans
Necrosis
Muscles
RNA Interference
27 Citations (Scopus)

Effects of silane- and MDP-based primers application orders on zirconia–resin adhesion—A ToF-SIMS study

Chuang, S. F., Kang, L. L., Liu, Y. C., Lin, J. C., Wang, C. C., Chen, H. M. & Tai, C. K., 2017 Aug, In : Dental Materials. 33, 8, p. 923-933 11 p.

Research output: Contribution to journalArticle

Secondary Ion Mass Spectrometry
Silanes
Secondary ion mass spectrometry
Phosphates
Zirconia
5 Citations (Scopus)

Octahedron Iron Oxide Nanocrystals Prohibited Clostridium difficile Spore Germination and Attenuated Local and Systemic Inflammation

Lee, W. T., Wu, Y. N., Chen, Y. H., Wu, S. R., Shih, T. M., Li, T. J., Yang, L. X., Yeh, C. S., Tsai, P. J. & Shieh, D. B., 2017 Dec 1, In : Scientific reports. 7, 1, 8124.

Research output: Contribution to journalArticle

Clostridium difficile
Germination
Spores
Nanoparticles
Inflammation
9 Citations (Scopus)

Preparation and characterization of porous bioceramic layers on pure titanium surfaces obtained by micro-arc oxidation process

Chien, C. S., Hung, Y. C., Hong, T. F., Wu, C. C., Kuo, T. Y., Lee, T. M., Liao, T. Y., Lin, H. C. & Chuang, C. H., 2017 Mar 1, In : Applied Physics A: Materials Science and Processing. 123, 3, 204.

Research output: Contribution to journalArticle

Bioceramics
Titanium
Oxidation
Durapatite
Hydroxyapatite
8 Citations (Scopus)

Surface modification of Direct-Current and radio-frequency oxygen plasma treatments enhance cell biocompatibility

Chou, W. C., Wang, R. C. C., Liu, C., Yang, C. Y. & Lee, T. M., 2017 Oct 25, In : Materials. 10, 11, 1223.

Research output: Contribution to journalArticle

Biocompatibility
Surface treatment
Oxygen
Plasmas
Topography
2016
6 Citations (Scopus)

Cell response on the biomimetic scaffold of silicon nano- and micro-topography

Yang, S. P., Wen, H. S., Lee, T. M. & Lui, T. S., 2016 Mar 14, In : Journal of Materials Chemistry B. 4, 10, p. 1891-1897 7 p.

Research output: Contribution to journalArticle

Biomimetics
Silicon
Scaffolds (biology)
Topography
Scaffolds
3 Citations (Scopus)

Dietary adaptions in the ultrastructure of dinosaur dentine

Brink, K. S., Chen, Y. C., Wu, Y. N., Liu, W. M., Shieh, D. B., Huang, T. D., Sun, C. K. & Reisz, R. R., 2016 Dec 1, In : Journal of the Royal Society Interface. 13, 125, 20160626.

Research output: Contribution to journalArticle

Dinosaurs
Dentin
Tooth
Ecology
Tissue
6 Citations (Scopus)

Handheld energy-efficient magneto-optical real-time quantitative PCR device for target DNA enrichment and quantification

Li, T. J., Chang, C. M., Chang, P. Y., Chuang, Y. C., Huang, C. C., Su, W. C. & Shieh, D. B., 2016 Jun 3, In : NPG Asia Materials. 8, 6, e277.

Research output: Contribution to journalArticle

Energy Efficient
Quantification
DNA
deoxyribonucleic acid
Heat
18 Citations (Scopus)

Immunological and biochemical characterizations of coxsackievirus A6 and A10 viral particles

Liu, C. C., Guo, M. S., Wu, S. R., Lin, H. Y., Yang, Y. T., Liu, W. C., Chow, Y. H., Shieh, D. B., Wang, J. R. & Chong, P., 2016 May 1, In : Antiviral Research. 129, p. 58-66 9 p.

Research output: Contribution to journalArticle

Enterovirus
antineoplaston A10
Virion
Hand, Foot and Mouth Disease
Vaccines
1 Citation (Scopus)
Nanorods
Gold
Cells
Nanoparticles
Imaging techniques
2 Citations (Scopus)

Nonionic microemulsions as solubilizers of hydrophobic drugs: Solubilization of paclitaxel

Lo, J. T., Lee, T. M. & Chen, B. H., 2016 Sep, In : Materials. 9, 9, 761.

Research output: Contribution to journalArticle

Microemulsions
Paclitaxel
Oils
Surface-Active Agents
Pharmaceutical Preparations
11 Citations (Scopus)

Shrinkage behaviors of dental composite restorations—The experimental–numerical hybrid analysis

Chuang, S. F., Huang, P. S., Chen, T. Y. F., Huang, L. H., Su, K. C. & Chang, C. H., 2016 Dec 1, In : Dental Materials. 32, 12, p. e362-e373

Research output: Contribution to journalArticle

Dental composites
Finite Element Analysis
Polymerization
Tooth
Light
3 Citations (Scopus)

Syntheses of Platinum-Sulindac Complexes and Their Nanoparticles as Targeted Anticancer Drugs

Hwu, J. R., Tsay, S. C., Chuang, K. S., Kapoor, M., Lin, J. Y., Yeh, C. S., Su, W. C., Wu, P. C., Tsai, T. L., Wang, P. W. & Shieh, D. B., 2016 Feb 5, In : Chemistry - A European Journal. 22, 6, p. 1926-1930 5 p.

Research output: Contribution to journalArticle

Sulindac
Platinum
Cells
Nanoparticles
Pharmaceutical Preparations
2015
10 Citations (Scopus)

2-Deoxy-D-glucose can complement doxorubicin and sorafenib to suppress the growth of papillary thyroid carcinoma cells

Wang, S. Y., Wei, Y. H., Shieh, D. B., Lin, L. L., Cheng, S. P., Wang, P. W. & Chuang, J. H., 2015 Jul 2, In : PloS one. 10, 7, e0130959.

Research output: Contribution to journalArticle

doxorubicin
Deoxyglucose
Doxorubicin
carcinoma
complement
40 Citations (Scopus)

Cell surface nucleolin facilitates enterovirus 71 binding and infection

Su, P. Y., Wang, Y. F., Huang, S. W., Lo, Y. C., Wang, Y. H., Wu, S. R., Shieh, D. B., Chen, S. H., Wang, J. R., Lai, M. D. & Chang, C. F., 2015 Jan 1, In : Journal of Virology. 89, 8, p. 4527-4538 12 p.

Research output: Contribution to journalArticle

Enterovirus
Infection
infection
cells
Enterovirus Infections
15 Citations (Scopus)

Characterization of the elastic and viscoelastic properties of dentin by a nanoindentation creep test

Chuang, S. F., Lin, S. Y., Wei, P. J., Han, C. F., Lin, J. F. & Chang, H. C., 2015 Jul 16, In : Journal of Biomechanics. 48, 10, p. 2155-2161 7 p.

Research output: Contribution to journalArticle

Dentin
Nanoindentation
Creep
Nanohardness
Minerals
9 Citations (Scopus)

Imaging Endogenous Bilirubins with Two-Photon Fluorescence of Bilirubin Dimers

Shen, Y. F., Tsai, M. R., Chen, S. C., Leung, Y. S., Hsieh, C. T., Chen, Y. S., Huang, F. L., Obena, R. P., Zwulueta, M. M. L., Huang, H. Y., Lee, W. J., Tang, K. C., Kung, C. T., Chen, M. H., Shieh, D. B., Chen, Y. J., Liu, T. M., Chou, P. T. & Sun, C. K., 2015 Aug 4, In : Analytical chemistry. 87, 15, p. 7575-7582 8 p.

Research output: Contribution to journalArticle

Bilirubin
Dimers
Photons
Fluorescence
Imaging techniques
18 Citations (Scopus)

Involvement of gelsolin in TGF-beta 1 induced epithelial to mesenchymal transition in breast cancer cells

Chen, Z. Y., Wang, P. W., Shieh, D. B., Chiu, K. Y. & Liou, Y. M., 2015 Oct 20, In : Journal of biomedical science. 22, 1 p.

Research output: Contribution to journalArticle

Gelsolin
Transforming Growth Factor beta1
Epithelial-Mesenchymal Transition
Cells
Breast Neoplasms
23 Citations (Scopus)

Mitochondrial dynamics regulating chemoresistance in gynecological cancers

Kong, B., Tsuyoshi, H., Orisaka, M., Shieh, D. B., Yoshida, Y. & Tsang, B. K., 2015 Jan 1, In : Annals of the New York Academy of Sciences. 1350, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Mitochondria
Neoplasms
Fusion reactions
Cells
5 Citations (Scopus)

Surface modification of titanium substrate with a novel covalently-bound copolymer thin film for improving its platelet compatibility

Shen, C. H., Cho, Y. J., Lin, Y. C., Chien, L. C., Lee, T. M., Chuang, W. H. & Lin, J. C., 2015 Jan 1, In : Journal of Materials Science: Materials in Medicine. 26, 2, p. 1-13 13 p.

Research output: Contribution to journalArticle

Platelets
Titanium
Surface treatment
Blood Platelets
Methacrylates
13 Citations (Scopus)

Third-harmonic generation microscopy reveals dental anatomy in ancient fossils

Chen, Y. C., Lee, S. Y., Wu, Y., Brink, K., Shieh, D. B., Huang, T. D., Reisz, R. R. & Sun, C. K., 2015 Jan 1, In : Optics Letters. 40, 7, p. 1354-1357 4 p.

Research output: Contribution to journalArticle

anatomy
fossils
teeth
harmonic generations
microscopy
2014
18 Citations (Scopus)
Dentinal Fluid
Mastication
Dental Pulp
Fluid structure interaction
Pulp
12 Citations (Scopus)

Antimicrobial applications of water-dispersible magnetic nanoparticles in biomedicine

Huang, K. S., Shieh, D. B., Yeh, C. S., Wu, P. C. & Cheng, F. Y., 2014 Jan 1, In : Current Medicinal Chemistry. 21, 29, p. 3312-3322 11 p.

Research output: Contribution to journalArticle

Nanoparticles
Water
Nanostructures
Nanostructured materials
Surface treatment
19 Citations (Scopus)

Cell fate regulation by gelsolin in human gynecologic cancers

Abedini, M. R., Wang, P. W., Huang, Y. F., Cao, M., Chou, C. Y., Shieh, D. B. & Tsang, B. K., 2014 Oct 7, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 40, p. 14442-14447 6 p.

Research output: Contribution to journalArticle

Gelsolin
CASP8 and FADD-Like Apoptosis Regulating Protein
Neoplasms
Apoptosis
Down-Regulation
5 Citations (Scopus)

Design and development of solar power-assisted manual/electric wheelchair

Chien, C. S., Huang, T. Y., Liao, T. Y., Kuo, T. Y. & Lee, T. M., 2014 Jan 1, In : Journal of Rehabilitation Research and Development. 51, 9, p. 1411-1426 16 p.

Research output: Contribution to journalArticle

Solar Energy
Wheelchairs
Electric Power Supplies
Upper Extremity
Wounds and Injuries
10 Citations (Scopus)

Evaluation of dentinal fluid flow behaviours: a fluid-structure interaction simulation

Su, K. C., Chuang, S. F., Ng, E. Y. K. & Chang, C. H., 2014 Nov, In : Computer Methods in Biomechanics and Biomedical Engineering. 17, 15, p. 1716-1726 11 p.

Research output: Contribution to journalArticle

Fluid structure interaction
Flow of fluids
Pulp
Biomechanics
Flow velocity
11 Citations (Scopus)

Gelsolin regulates cisplatin sensitivity in human head-and-neck cancer

Wang, P. W., Abedini, M. R., Yang, L. X., Ding, A. A., Figeys, D., Chang, J. Y., Tsang, B. K. & Shieh, D. B., 2014 Dec 15, In : International Journal of Cancer. 135, 12, p. 2760-2769 10 p.

Research output: Contribution to journalArticle

Gelsolin
Head and Neck Neoplasms
Cisplatin
X-Linked Inhibitor of Apoptosis Protein
Apoptosis
7 Citations (Scopus)

Nanomaterial-mediated photothermal cancer treatment: The pivotal role of cellular uptake on photothermal therapeutic efficacy

Wu, P. C., Shieh, D. B. & Cheng, F. Y., 2014, In : RSC Advances. 4, 95, p. 53297-53306 10 p.

Research output: Contribution to journalArticle

Oncology
Nanostructured materials
Cells
Nanoshells
Chlorpromazine
10 Citations (Scopus)

Single domain antibody against carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) inhibits proliferation, migration, invasion and angiogenesis of pancreatic cancer cells

Cheng, T. M., Murad, Y. M., Chang, C. C., Yang, M. C., Baral, T. N., Cowan, A., Tseng, S. H., Wong, A., Mackenzie, R., Shieh, D. B. & Zhang, J., 2014 Mar 1, In : European Journal of Cancer. 50, 4, p. 713-721 9 p.

Research output: Contribution to journalArticle

Single-Domain Antibodies
gemcitabine
Carcinoembryonic Antigen
Cell Adhesion Molecules
Pancreatic Neoplasms
2013
12 Citations (Scopus)

Enhancing biological properties of porous coatings through the incorporation of manganese

Liu, Y. T., Kung, K. C., Lee, T. M. & Lui, T. S., 2013 Jan 1, In : Journal of Alloys and Compounds. 581, p. 459-467 9 p.

Research output: Contribution to journalArticle

Manganese
Coatings
Titanium
Oxidation
Topography
4 Citations (Scopus)

Integrated three-dimensional system-on-chip for direct quantitative detection of mitochondrial DNA mutation in affected cells

Chang, C. M., Chiu, L. F., Wei, Y. H., Shieh, D. B. & Lee, G. B., 2013 Oct 5, In : Biosensors and Bioelectronics. 48, p. 6-11 6 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Microfluidics
DNA
Mutation
Purification
7 Citations (Scopus)
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
Endoplasmic Reticulum Stress
Cell death
Phosphatidylinositol 3-Kinases
Surface-Active Agents
25 Citations (Scopus)

Riboflavin-ultraviolet-A-induced collagen cross-linking treatments in improving dentin bonding

Chiang, Y. S., Chen, Y. L., Chuang, S. F., Wu, C. M., Wei, P. J., Han, C. F., Lin, J. C. & Chang, H. T., 2013 Jun 1, In : Dental Materials. 29, 6, p. 682-692 11 p.

Research output: Contribution to journalArticle

Riboflavin
Dentin
Collagen
Glutaral
Electrophoresis
6 Citations (Scopus)

Synthesis of apolipoprotein B lipoparticles to deliver hydrophobic/ amphiphilic materials

Chu, H. L., Cheng, T. M., Chen, H. W., Chou, F. H., Chang, Y. C., Lin, H. Y., Liu, S. Y., Liang, Y. C., Hsu, M. H., Wu, D. S., Li, H. Y., Ho, L. P., Wu, P. C., Chen, F. R., Chen, G. S., Shieh, D. B., Chang, C. S., Su, C. H., Yao, Z. & Chang, C. C., 2013 Aug 14, In : ACS Applied Materials and Interfaces. 5, 15, p. 7509-7516 8 p.

Research output: Contribution to journalArticle

Lipoproteins
Apolipoproteins B
Iron oxides
LDL Lipoproteins
Nanoparticles
17 Citations (Scopus)

The anticancer properties of iron core-gold shell nanoparticles in colorectal cancer cells

Wu, Y. N., Wu, P. C., Yang, L. X., Ratinac, K. R., Thordarson, P., Jahn, K. A., Chen, D. H., Shieh, D. B. & Braet, F., 2013 Aug 30, In : International journal of nanomedicine. 8, p. 3321-3331 11 p.

Research output: Contribution to journalArticle

Gold
Nanoparticles
Colorectal Neoplasms
Iron
Cells
2012
10 Citations (Scopus)
Cell Nucleus Active Transport
Autophagy
Cell death
Gold
Nanoparticles