Research Output 1972 2019

2019

Acrofolione A and B, acetophenone dimers from Acronychia pendunculata, induce an apoptotic effect on human NALM-6 pre-B cell leukaemia cells

Matsui, T., Ito, C., Kato, A., Wu, T. S. & Itoigawa, M., 2019 Mar, In : Journal of Pharmacy and Pharmacology. 71, 3, p. 348-361 14 p.

Research output: Contribution to journalArticle

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Rutaceae
Caspase 7
Caspase 3
Annexin A5

Bioassay-guided purification of sesquiterpenoids from the fruiting bodies of: Fomitopsis pinicola and their anti-inflammatory activity

Tai, S. H., Kuo, P. C., Hung, C. C., Lin, Y. H., Hwang, T. L., Lam, S. H., Kuo, D. H., Wu, J. B., Hung, H. Y. & Wu, T. S., 2019 Jan 1, In : RSC Advances. 9, 59, p. 34184-34195 12 p.

Research output: Contribution to journalArticle

Open Access
Bioassay
Fungi
Purification
Anti-Inflammatory Agents
Negative ions

Characterization of Cytochalasins and Steroids from the Ascomycete Daldinia concentrica and Their Cytotoxicity

Van Trung, H., Kuo, P. C., Tuan, N. N., Ngan, N. T., Trung, N. Q., Thanh, N. T., Hai, H. V., Phuong, D. L., Giang, B. L., Li, Y. C., Wu, T. S. & Thang, T. D., 2019 May, In : Natural Product Communications. 14, 5

Research output: Contribution to journalArticle

Open Access
Cytochalasins
cytochalasins
Ascomycota
steroids
cytotoxicity
Open Access
Orchidaceae
Phalaenopsis
flavone
extracts
flavones

Chemical constituents from the stems of Machilus philippinensis Merr. and the neuroprotective activity of cinnamophilin

Tai, S. H., Kuo, P. C., Lam, S. H., Huang, S. C., Kuo, Y. Z., Hung, H. Y., Liou, M. J., Shieh, P. C., Lee, E. J. & Wu, T. S., 2019 Jan 1, In : RSC Advances. 9, 38, p. 21616-21625 10 p.

Research output: Contribution to journalArticle

Open Access
Acids
Bioactivity
Neurons
Medicine
Methanol
2 Citations (Scopus)

Chemical Constituents of the Leaves of Peltophorum pterocarpum and Their Bioactivity

Li, Y. C., Kuo, P. C., Yang, M. L., Chen, T. Y., Hwang, T. L., Chiang, C. C., Thang, T. D., Tuan, N. N. & Tzen, J. T. C., 2019 Jan 10, In : Molecules. 24, 2, 240.

Research output: Contribution to journalArticle

inorganic peroxides
Pancreatic Elastase
Bioactivity
Superoxides
leaves
1 Citation (Scopus)

Chemical constituents of vigna luteola and their anti-inflammatory bioactivity

Lam, S. H., Li, Y. C., Kuo, P. C., Hwang, T. L., Yang, M. L., Wang, C. C. & Tzen, J. T. C., 2019 Jan 1, In : Molecules. 24, 7, 1371.

Research output: Contribution to journalArticle

Open Access
inorganic peroxides
Pancreatic Elastase
Bioactivity
Superoxides
Methanol

Comparative risk evaluation for cardiovascular events associated with dapagliflozin vs. empagliflozin in real-world type 2 diabetes patients: A multi-institutional cohort study

Shao, S. C., Chang, K. C., Hung, M. J., Yang, N. I., Chan, Y. Y., Chen, H. Y., Kao Yang, Y. H. & Lai, E. C. C., 2019 Sep 24, In : Cardiovascular Diabetology. 18, 1, 120.

Research output: Contribution to journalArticle

Open Access
Type 2 Diabetes Mellitus
Sodium-Glucose Transporter 2
Cohort Studies
Symporters
Heart Failure

Composition of Fatty Acids, Tocopherols, Sterols, Total Phenolics, and Antioxidant Activity of Seed Oils of Afzelia xylocarpa and Cassia fistula

Phuong, D. L., Thuy, N. T., Long, P. Q., Kuo, P-C. & Thang, T. D., 2019 Mar 15, In : Chemistry of Natural Compounds. 55, 2, p. 242-246 5 p.

Research output: Contribution to journalArticle

Afzelia
Cassia fistula
seed oils
tocopherols
sterols

Constituents and anti-multidrug resistance activity of taiwanofungus camphoratus on human cervical cancer cells

Hung, H. Y., Hung, C. C., Liang, J. W., Chen, C. F., Chen, H. Y., Shieh, P. C., Kuo, P. C. & Wu, T. S., 2019 Oct 16, In : Molecules. 24, 20, 3730.

Research output: Contribution to journalArticle

Open Access
Multiple Drug Resistance
P-Glycoprotein
Uterine Cervical Neoplasms
cancer
Cells
7 Citations (Scopus)

Detecting potential adverse drug reactions using a deep neural network model

Wang, C. S., Lin, P. J., Cheng, C-L., Tai, S. H., Kao, Y-H. & Chiang, J-H., 2019 Feb 1, In : Journal of medical Internet research. 21, 2, e11016.

Research output: Contribution to journalArticle

Neural Networks (Computer)
Drug-Related Side Effects and Adverse Reactions
Pharmaceutical Preparations
Pharmacovigilance
ROC Curve
Kaurane Diterpenes
Croton
Diterpenes
Euphorbiaceae
Euphorbia
Open Access
Taiwan
Non-Small Cell Lung Carcinoma
Therapeutics
National Health Programs
Interrupted Time Series Analysis

Effects of sodium-glucose co-transporter-2 inhibitors on serum alanine aminotransferase levels in people with type 2 diabetes: A multi-institutional cohort study

Shao, S. C., Chang, K. C., Chien, R. N., Lin, S. J., Hung, M. J., Chan, Y. Y., Kao Yang, Y. H. & Lai, E. C. C., 2019 Jan 1, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

Sodium-Glucose Transporter 2
Symporters
Alanine Transaminase
Type 2 Diabetes Mellitus
Cohort Studies

Elucidating metal and ligand redox activities of a copper-benzoquinoid coordination polymer as the cathode for lithium-ion batteries

Chang, C. H., Li, A. C., Popovs, I., Kaveevivitchai, W., Chen, J. L., Chou, K. C., Kuo, T. S. & Chen, T. H., 2019 Jan 1, In : Journal of Materials Chemistry A. 7, 41, p. 23770-23774 5 p.

Research output: Contribution to journalArticle

Redox reactions
Energy storage
Copper
Polymers
Cathodes

High resolution/accurate mass tandem MS of isotopically complex cluster ions from the artists’ pigment lead white

Napolitano, M. P., Conaway, M. C. P., Kuo, P-C., Arslanoglu, J. & Yost, R. A., 2019 May 1, In : International Journal of Mass Spectrometry. 439, p. 19-26 8 p.

Research output: Contribution to journalArticle

pigments
Pigments
Lead
Ions
high resolution

Identification of two teaghrelins in Shy-jih-chuen oolong tea

Li, Y. C., Wu, C. J., Lin, Y. C., Wu, R. H., Chen, W. Y., Kuo, P-C. & Tzen, J. T. C., 2019 Apr 1, In : Journal of Food Biochemistry. 43, 4, e12810.

Research output: Contribution to journalArticle

Tea
Chin
Flavonoids
flavonoids
tea (beverage)
2 Citations (Scopus)

Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: Population based cohort study

Wei, L., Lai, E. C. C., Kao-Yang, Y. H., Walker, B. R., MacDonald, T. M. & Andrew, R., 2019 Jan 1, In : BMJ (Online). 365, l1204.

Research output: Contribution to journalArticle

Open Access
tamsulosin
Finasteride
Type 2 Diabetes Mellitus
Oxidoreductases
Cohort Studies
Myositis
Taiwan
Coronary Disease
Population
Cohort Studies
1 Citation (Scopus)

Letter: contraindicated drug-drug interactions before and after initiation of direct-acting anti-viral agents in chronic hepatitis C patients in Taiwan

Shao, S. C., Lai, E. C. C., Chang, K. C., Chan, Y. Y., Chen, H. Y. & Chien, R. N., 2019 Jul, In : Alimentary Pharmacology and Therapeutics. 50, 1, p. 113-115 3 p.

Research output: Contribution to journalLetter

Open Access

Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors

Hsueh, Y. S., Chang, H. H., Shan, Y. S., Sun, H. S., Fletcher, J. A., Li, C. F. & Chen, L. T., 2019 Sep 19, In : Oncogene. 38, 38, p. 6550-6565 16 p.

Research output: Contribution to journalArticle

Open Access
Gastrointestinal Stromal Tumors
Stromal Cells
Chromatin Immunoprecipitation
Valproic Acid
Carcinogenesis
7 Citations (Scopus)

Taiwan’s national health insurance research database: Past and future

Hsieh, C. Y., Su, C. C., Shao, S. C., Sung, S. F., Lin, S. J., Kao, Y-H. & Lai, E., 2019 Jan 1, In : Clinical Epidemiology. 11, p. 349-358 10 p.

Research output: Contribution to journalReview article

Open Access
National Health Programs
Databases
Research
Health
Information Storage and Retrieval
4 Citations (Scopus)

The Chang Gung Research Database—A multi-institutional electronic medical records database for real-world epidemiological studies in Taiwan

Shao, S. C., Chan, Y. Y., Kao, Y-H., Lin, S. J., Hung, M. J., Chien, R. N., Lai, C. C. & Lai, E., 2019 May 1, In : Pharmacoepidemiology and drug safety. 28, 5, p. 593-600 8 p.

Research output: Contribution to journalArticle

Electronic Health Records
Taiwan
Epidemiologic Studies
Databases
Research

Triterpenoids and steroids from the fruiting bodies of Hexagonia tenuis and their cytotoxicity

Hung, D. X., Kuo, P-C., Tuan, N. N., Van Trung, H., Tan Thanh, N., Thi Ha, N., Long Giang, B., Quang Trung, N., Thi Ngan, N., Hai, H. V., Lan Phuong, D., Quang, D. N. & Thang, T. D., 2019 Jan 1, In : Natural Product Research.

Research output: Contribution to journalArticle

Hexagonia tenuis
Cytotoxicity
fruiting bodies
Tumor Cell Line
triterpenoids

Use of hydrochlorothiazide and risk of skin cancer: a nationwide Taiwanese case–control study

Pottegård, A., Pedersen, S. A., Schmidt, S. A. J., Lee, C. N., Hsu, C. K., Liao, T. C., Shao, S. C. & Lai, E. C. C., 2019 Jan 1, (Accepted/In press) In : British Journal of Cancer.

Research output: Contribution to journalArticle

Hydrochlorothiazide
Skin Neoplasms
Lip Neoplasms
Melanoma
Odds Ratio
2018
4 Citations (Scopus)

A feasible and practical 1H NMR analytical method for the quality control and quantification of bioactive principles in Lycii Fructus

Hsieh, L. Y., Chan, H. H., Kuo, P-C., Hung, H-Y., Li, Y. C., Kuo, C. L., Peng, Y., Zhao, Z. Z., Kuo, D. H., Sun, I-W. & Wu, T-S., 2018 Jul 1, In : Journal of Food and Drug Analysis. 26, 3, p. 1105-1112 8 p.

Research output: Contribution to journalArticle

Quality Control
quality control
analytical methods
Betaine
betaine
3 Citations (Scopus)

Anti-cell proliferation effect of naphthoquinone dimers isolated from Plumbago zeylanica

Ito, C., Matsui, T., Takano, M., Wu, T-S. & Itoigawa, M., 2018 Sep 17, In : Natural Product Research. 32, 18, p. 2127-2132 6 p.

Research output: Contribution to journalArticle

Plumbaginaceae
Plumbago zeylanica
Naphthoquinones
naphthoquinones
Cell proliferation
2 Citations (Scopus)

Applying a common data model to asian databases for multinational pharmacoepidemiologic studies: Opportunities and challenges

Lai, E., Ryan, P., Zhang, Y., Schuemie, M., Hardy, N. C., Kamijima, Y., Kimura, S., Kubota, K., Man, K. K. C., Cho, S. Y., Park, R. W., Stang, P., Su, C. C., Wong, I. C. K., Kao, Y-H. & Setoguchi, S., 2018 Jan 1, In : Clinical Epidemiology. 10, p. 875-885 11 p.

Research output: Contribution to journalArticle

RxNorm
Databases
Terminology
Pharmacoepidemiology
Pharmaceutical Preparations
14 Citations (Scopus)
clopidogrel
Taiwan
Myocardial Infarction
Hemorrhage
Safety
2 Citations (Scopus)

Characterization of vasorelaxant principles from the needles of pinus morrisonicola hayata

Chen, G. H., Li, Y. C., Lin, N. H., Kuo, P-C. & Tzen, J. T. C., 2018 Jan 1, In : Molecules. 23, 1, 86.

Research output: Contribution to journalArticle

Pinus
Taiwan
Vasodilator Agents
needles
Needles

Chemical constituents from the fruiting bodies of Phellinus igniarius

Thanh, N. T., Tuan, N. N., Kuo, P-C., Dung, D. M., Phuong, D. L., Giang, D. T. T., Wu, T-S. & Thang, T. D., 2018 Oct 18, In : Natural Product Research. 32, 20, p. 2392-2397 6 p.

Research output: Contribution to journalArticle

Phellinus igniarius
Ergosterol
ergosterol
Cytotoxicity
fruiting bodies
2 Citations (Scopus)

Chemical constituents from the stems of tinospora sinensis and their bioactivity

Lam, S. H., Chen, P. H., Hung, H. Y., Hwang, T. L., Chiang, C. C., Thang, T. D., Kuo, P. C. & Wu, T. S., 2018 Oct 5, In : Molecules. 23, 10, 2541.

Research output: Contribution to journalArticle

Tinospora
N-Formylmethionine Leucyl-Phenylalanine
Lignans
Cytochalasin B
Pyrroles

Comparative safety of NSAIDs for gastrointestinal events in Asia-Pacific populations: A multi-database, international cohort study

Lai, E., Shin, J. Y., Kubota, K., Man, K. K. C., Park, B. J., Pratt, N., Roughead, E. E., Wong, I. C. K., Kao, Y-H. & Setoguchi, S., 2018 Nov 1, In : Pharmacoepidemiology and drug safety. 27, 11, p. 1223-1230 8 p.

Research output: Contribution to journalArticle

Gastrointestinal Agents
Korea
Mefenamic Acid
Cohort Studies
Anti-Inflammatory Agents
1 Citation (Scopus)

Detection of lithospermate B in rat plasma at the nanogram level by LC/MS in multi reaction monitoring mode

Chung, T. Y., Lin, N. H., Li, Y. C., Chen, T. Y., Kuo, P-C., Chen, W. Y. & Tzen, J. T. C., 2018 Jan 1, In : Journal of Food and Drug Analysis. 26, 1, p. 353-361 9 p.

Research output: Contribution to journalArticle

caffeic acid
blood proteins
bioavailability
monitoring
formic acid
3 Citations (Scopus)

Disease and economic burden for rare diseases in Taiwan: A longitudinal study using Taiwan’s National Health Insurance Research Database

Hsu, J. C., Wu, H. C., Feng, W. C., Chou, C. H., Lai, E. & Lu, C. Y., 2018 Sep 1, In : PloS one. 13, 9, e0204206.

Research output: Contribution to journalArticle

Health insurance
health care costs
health insurance
Cost of Illness
National Health Programs
16 Citations (Scopus)

Dissecting Porosity in Molecular Crystals: Influence of Geometry, Hydrogen Bonding, and [π···π] Stacking on the Solid-State Packing of Fluorinated Aromatics

Hashim, M. I., Le, H. T. M., Chen, T. H., Chen, Y. S., Daugulis, O., Hsu, C. W., Jacobson, A. J., Kaveevivitchai, W., Liang, X., Makarenko, T., Miljanić, O., Popovs, I., Tran, H. V., Wang, X., Wu, C. H. & Wu, J. I., 2018 May 9, In : Journal of the American Chemical Society. 140, 18, p. 6014-6026 13 p.

Research output: Contribution to journalArticle

Molecular crystals
Porosity
Hydrogen Bonding
Hydrogen bonds
Electrons
1 Citation (Scopus)

Effectiveness and safety of immune checkpoint inhibitors: A retrospective study in Taiwan

Hsu, J. C., Lin, J. Y., Hsu, M. Y. & Lin, P-C., 2018 Aug 1, In : PloS one. 13, 8, e0202725.

Research output: Contribution to journalArticle

Taiwan
retrospective studies
lung neoplasms
Non-Small Cell Lung Carcinoma
Oncology
2 Citations (Scopus)

Effect of teapot materials on the chemical composition of oolong tea infusions

Liao, Z. H., Chen, Y. J., Tzen, J. T. C., Kuo, P-C., Lee, M. R., Mai, F. D., Rairat, T. & Chou, C. C., 2018 Jan 30, In : Journal of the Science of Food and Agriculture. 98, 2, p. 751-757 7 p.

Research output: Contribution to journalArticle

Tea
tea
chemical composition
ceramics
stainless steel
Major Depressive Disorder
Body Mass Index
Homeostasis
Fingers
Insulin Resistance
2 Citations (Scopus)

Fatty acid, tocopherol, sterol compositions and antioxidant activity of three Garcinia seed oils

Phương, D. L., Thuy, N. T., Long, P. Q., Quan, P. M., Thuy, T. T. T., Minh, P. T. H., Kuo, P. C. & Thang, T. D., 2018 Jan 1, In : Records of Natural Products. 12, 4, p. 323-331 9 p.

Research output: Contribution to journalArticle

Garcinia
Oilseeds
Tocopherols
Sterols
seed oils
3 Citations (Scopus)
Valproic Acid
Bipolar Disorder
Therapeutics
Depression
Body Weight
1 Citation (Scopus)

Fractures and the increased risk of suicide: A population-based case-control study

Chang, C. F., Lai, E. & Yeh, M. K., 2018 Jun 1, In : Bone and Joint Journal. 100B, 6, p. 780-786 7 p.

Research output: Contribution to journalArticle

Suicide
Case-Control Studies
Population
Odds Ratio
Confidence Intervals
1 Citation (Scopus)

Hepatoprotective Principles and Other Chemical Constituents from the Mycelium of Phellinus linteus

Huang, S. C., Wang, P. W., Kuo, P. C., Hung, H. Y. & Pan, T. L., 2018 Jul 12, In : Molecules (Basel, Switzerland). 23, 7

Research output: Contribution to journalArticle

fibrosis
Mycelium
rats
Rats
Norisoprenoids
2 Citations (Scopus)

Look-Alike Medication Packages and Patient Safety

Shao, S. C., Lai, E., Owang, K. L., Chen, H. Y. & Chan, Y. Y., 2018 Sep 1, In : Journal of Patient Safety. 14, 3, p. e47-e48

Research output: Contribution to journalArticle

Product Packaging
Patient Safety
Medication Errors
Pharmacists
Industry
11 Citations (Scopus)

Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress

Lin, Y. W., Chen, T. Y., Hung, C. Y., Tai, S-H., Huang, S. Y., Chang, C-C., Hung, H-Y. & Lee, E-J., 2018 Jul 1, In : International journal of molecular medicine. 42, 1, p. 182-192 11 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Melatonin
Reperfusion Injury
Brain Ischemia
Eukaryotic Initiation Factor-2

Methotrexate-induced pancytopenia in a patient with ectopic pregnancy

Shao, S. C., Yang, Y. H. K., Chien, P. S. & Lai, E. C. C., 2018 Mar, In : Archives of Medical Science. 14, 2, p. 475-476 2 p.

Research output: Contribution to journalLetter

Pancytopenia
Ectopic Pregnancy
Methotrexate
1 Citation (Scopus)
Dendritic Spines
Transient Ischemic Attack
Brain Ischemia
Neuronal Plasticity
Stroke
1 Citation (Scopus)

Pay for performance program reduces treatment needed diabetic retinopathy - A nationwide matched cohort study in Taiwan

Sheu, S. J., Lin, W. L., Kao, Y-H., Hwu, C. M. & Cheng, C-L., 2018 Aug 15, In : BMC Health Services Research. 18, 1, 638.

Research output: Contribution to journalArticle

Incentive Reimbursement
Diabetic Retinopathy
Taiwan
Cohort Studies
Therapeutics

Penetration of new antidiabetic medications in East Asian countries and the United States: A cross-national comparative study

Kubota, K., Kamijima, Y., Kao, Y-H., Kimura, S., Lai, E., Man, K. K. C., Ryan, P., Schuemie, M., Stang, P., Su, C. C., Wong, I. C. K., Zhang, Y. & Setoguchi, S., 2018 Dec 1, In : PloS one. 13, 12, e0208796.

Research output: Contribution to journalArticle

hypoglycemic agents
Dipeptidyl-Peptidase IV Inhibitors
Hong Kong
East Asia
Hypoglycemic Agents