University Center for Bioscience and Biotechnology

Research Output 1992 2020

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2020

Continuous production of algicidal compounds against Akashiwo sanguinea via a Vibrio sp. co-culture

Wang, Y., Li, S., Liu, G., Li, X., Yang, Q., Xu, Y., Hu, Z., Chen, C. Y. & Chang, J. S., 2020 Jan, In : Bioresource technology. 295, 122246.

Research output: Contribution to journalArticle

physical method
chemical method
lysis
Antioxidants
Malondialdehyde

Enhanced production of microalgal lipids using a heterotrophic marine microalga Thraustochytrium sp. BM2

Chen, C. Y., Lee, M. H., Dong, C. D., Leong, Y. K. & Chang, J. S., 2020 Feb 15, In : Biochemical Engineering Journal. 154, 107429.

Research output: Contribution to journalArticle

Lipids
Glycerol
Zea mays
Nitrogen
Carbon

Examination of indigenous microalgal species for maximal protein synthesis

Tan, C. H., Show, P. L., Lam, M. K., Fu, X., Ling, T. C., Chen, C. Y. & Chang, J. S., 2020 Feb 15, In : Biochemical Engineering Journal. 154, 107425.

Research output: Contribution to journalArticle

Proteins
Chlorella vulgaris
Chlorella
Biomass
Productivity
2019
1 Citation (Scopus)

Analysis of ambient temperature-responsive transcriptome in shoot apical meristem of heat-tolerant and heat-sensitive broccoli inbred lines during floral head formation

Lin, C. W., Fu, S. F., Liu, Y. J., Chen, C. C., Chang, C. H., Yang, Y. W. & Huang, H. J., 2019 Jan 3, In : BMC Plant Biology. 19, 1, 3.

Research output: Contribution to journalArticle

shoot meristems
broccoli
apical meristems
transcriptome
inbred lines

Crystal Structures of the C-Terminally Truncated Endoglucanase Cel9Q from Clostridium thermocellum Complexed with Cellodextrins and Tris

Jeng, W. Y., Liu, C. I., Lu, T. J., Lin, H. J., Wang, N. C. & Wang, A. H. J., 2019 Jan 18, In : ChemBioChem. 20, 2, p. 295-307 13 p.

Research output: Contribution to journalArticle

Clostridium thermocellum
Cellobiose
Clostridium
Cellulase
Crystal structure
6 Citations (Scopus)

Enhancing lutein production with mixotrophic cultivation of Chlorella sorokiniana MB-1-M12 using different bioprocess operation strategies

Chen, J. H., Chen, C-Y., Hasunuma, T., Kondo, A., Chang, C-H., Ng, I-S. & Chang, J-S., 2019 Apr 1, In : Bioresource technology. 278, p. 17-25 9 p.

Research output: Contribution to journalArticle

Lutein
Productivity
productivity
replacement
Photobioreactors
2 Citations (Scopus)

Enterovirus A71 containing codon-deoptimized VP1 and high-fidelity polymerase as next-generation vaccine candidate

Tsai, Y. H., Huang, S. W., Hsieh, W. S., Cheng, C. K., Chang, C-F., Wang, Y. F. & Wang, J-R., 2019 Jan 1, In : Journal of Virology. 93, 13, e02308-18.

Research output: Contribution to journalArticle

Enterovirus
codons
Codon
Vaccines
vaccines
1 Citation (Scopus)

Glycoproteomic identification of novel plasma biomarkers for oral cancer

Chang, S. C., Lin, W. L., Chang, Y-F., Lee, C-T., Wu, J-S., Hsu, P. H. & Chang, C-F., 2019 Apr 1, In : Journal of Food and Drug Analysis. 27, 2, p. 483-493 11 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
biomarkers
Biomarkers
glycoproteins
Glycoproteins

Isolation and characterization of Chlorella sp. mutants with enhanced thermo- And CO2 tolerances for CO2 sequestration and utilization of flue gases

Chou, H. H., Su, H. Y., Song, X. D., Chow, T. J., Chen, C. Y., Chang, J. S. & Lee, T. M., 2019 Oct 19, In : Biotechnology for Biofuels. 12, 1, 251.

Research output: Contribution to journalArticle

Open Access
Chlorella
Flue gases
carbon sequestration
tolerance
Gases

Microbial volatile compounds-induced cytotoxicity in the yeast Saccharomyces cerevisiae: The role of MAPK signaling and proteasome regulatory pathway

Wu, P. H., Ho, Y. L., Ho, T. S., Chang, C. H., Ye, J. C., Wang, C. H., Sung, H. M., Huang, H. J. & Liu, C. C., 2019 Oct, In : Chemosphere. 233, p. 786-795 10 p.

Research output: Contribution to journalArticle

Volatile Organic Compounds
Proteasome Endopeptidase Complex
Cytotoxicity
Volatile organic compounds
Yeast

Revegetation on abandoned salt ponds relieves the seasonal fluctuation of soil microbiomes

Tran, H. T., Wang, H. C., Hsu, T. W., Sarkar, R., Huang, C. L. & Chiang, T. Y., 2019 Jun 11, In : BMC genomics. 20, 1, 478.

Research output: Contribution to journalArticle

Open Access
Microbiota
Salt-Tolerant Plants
Soil
Salts
Environmental Biodegradation
1 Citation (Scopus)

Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer

Chuang, P. K., Hsiao, M., Hsu, T. L., Chang, C-F., Wu, C. Y., Chen, B. R., Huang, H. W., Liao, K. S., Chen, C. C., Chen, C. L., Yang, S. M., Kuo, C. W., Chen, P., Chiu, P. T., Chen, I. J., Lai, J. S., Yu, C. D. T. & Wong, C. H., 2019 Feb 26, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3518-3523 6 p.

Research output: Contribution to journalArticle

Galactosyltransferases
Glycosphingolipids
Receptor-Interacting Protein Serine-Threonine Kinases
Protein Kinases
Breast Neoplasms

Targeted delivery of curcumin rescues endoplasmic reticulum-retained mutant Nox2 protein and avoids leukocyte apoptosis

Yen, C. L., Liao, Y. C., Chen, R. F., Huang, Y. F., Chung, W. C., Lo, P. C., Chang, C. F., Wu, P. C., Shieh, D. B., Jiang, S. T. & Shieh, C. C., 2019 Jun 15, In : Journal of Immunology. 202, 12, p. 3394-3403 10 p.

Research output: Contribution to journalArticle

Curcumin
Mutant Proteins
Endoplasmic Reticulum
Leukocytes
Apoptosis

Towards protein production and application by using Chlorella species as circular economy

Lai, Y. C., Chang, C-H., Chen, C-Y., Chang, J-S. & Ng, I-S., 2019 Oct 1, In : Bioresource technology. 289, 121625.

Research output: Contribution to journalArticle

Proteins
protein
Prebiotics
Essential Amino Acids
Pathogens
2018
20 Citations (Scopus)

A highly efficient two-stage cultivation strategy for lutein production using heterotrophic culture of Chlorella sorokiniana MB-1-M12

Chen, C-Y., Lu, I. C., Nagarajan, D., Chang, C-H., Ng, I-S., Lee, D. J. & Chang, J-S., 2018 Apr 1, In : Bioresource Technology. 253, p. 141-147 7 p.

Research output: Contribution to journalArticle

Lutein
Productivity
productivity
Biomass
biomass
3 Citations (Scopus)
Docosahexaenoic Acids
Fermentation
Technology
Acids
Fermenters
13 Citations (Scopus)

Combining light strategies with recycled medium to enhance the economic feasibility of phycocyanin production with Spirulina platensis

Ho, S. H., Liao, J. F., Chen, C-Y. & Chang, J-S., 2018 Jan 1, In : Bioresource Technology. 247, p. 669-675 7 p.

Research output: Contribution to journalArticle

Phycocyanin
Spirulina
Light emitting diodes
Productivity
Economics

Detection of adulterated drugs in traditional Chinese medicine and dietary supplements using hydrogen as a carrier gas

Lin, Y. P., Lee, Y. L., Hung, C. Y., Chang, C-F. & Chen, Y., 2018 Oct 1, In : PloS one. 13, 10, e0205371.

Research output: Contribution to journalArticle

Dietary supplements
Chinese Traditional Medicine
Dietary Supplements
hydrogen
Medicine
1 Citation (Scopus)

Eicosapentaenoic acid production from Nannochloropsis oceanica CY2 using deep sea water in outdoor plastic-bag type photobioreactors

Chen, C-Y., Nagarajan, D. & Cheah, W. Y., 2018 Apr 1, In : Bioresource Technology. 253, p. 1-7 7 p.

Research output: Contribution to journalArticle

Photobioreactors
Eicosapentaenoic Acid
deep sea
deep water
plastic
1 Citation (Scopus)
Coke
Waste Water
Lipids
Effluents
Biomass
8 Citations (Scopus)

Enhancing carbon capture and lipid accumulation by genetic carbonic anhydrase in microalgae

Lin, W. R., Lai, Y. C., Sung, P. K., Tan, S. I., Chang, C-H., Chen, C-Y., Chang, J-S. & Ng, I-S., 2018 Dec 1, In : Journal of the Taiwan Institute of Chemical Engineers. 93, p. 131-141 11 p.

Research output: Contribution to journalArticle

Carbonic anhydrase
Carbon capture
Carbonic Anhydrases
Lipids
Algae

Glycan-binding preferences and genetic evolution of human seasonal influenza A (H3N2) viruses during 1999-2007 in Taiwan

Wang, Y. F., Chang, C. F., Tsai, H. P., Chi, C. Y., Su, I. J. & Wang, J. R., 2018 May, In : PloS one. 13, 5, e0196727.

Research output: Contribution to journalArticle

H3N2 Subtype Influenza A Virus
Molecular Evolution
Influenza A virus
Taiwan
Viruses
3 Citations (Scopus)

Highly diverse endophytes in roots of Cycas bifida (Cycadaceae), an ancient but endangered gymnosperm

Zheng, Y., Chiang, T-Y., Huang, C-L. & Gong, X., 2018 May 1, In : Journal of Microbiology. 56, 5, p. 337-345 9 p.

Research output: Contribution to journalArticle

Cycas
Gymnosperms
Endophytes
Cyanobacteria
Hyphomicrobiaceae
3 Citations (Scopus)

Novel subunit vaccine with linear array epitope protect giant grouper against nervous necrosis virus infection

Lin, C. F., Jiang, H. K., Chen, N. C., Wang, T. Y. & Chen, T-Y., 2018 Mar 1, In : Fish and Shellfish Immunology. 74, p. 551-558 8 p.

Research output: Contribution to journalArticle

Subunit Vaccines
grouper
subunit vaccines
vaccine
Viruses
6 Citations (Scopus)

Optimization of lutein production with a two-stage mixotrophic cultivation system with Chlorella sorokiniana MB-1

Chen, C-Y. & Liu, C. C., 2018 Aug 1, In : Bioresource Technology. 262, p. 74-79 6 p.

Research output: Contribution to journalArticle

Lutein
Productivity
productivity
Biomass
biomass
2 Citations (Scopus)

Paddy-upland rotation for sustainable agriculture with regards to diverse soil microbial community

Hou, P. F., Chien, C. H., Chiang-Hsieh, Y. F., Tseng, K. C., Chow, C. N., Huang, H. J. & Chang, W. C., 2018 Dec 1, In : Scientific reports. 8, 1, 7966.

Research output: Contribution to journalArticle

alternative agriculture
microbial community
soil
disease resistance
bioassay
3 Citations (Scopus)

Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells

Chen, H. P., Lee, Y. K., Huang, S. Y., Shi, P. C., Hsu, P. C. & Chang, C. F., 2018 Jan 1, In : Oncotarget. 9, 17, p. 13167-13180 14 p.

Research output: Contribution to journalArticle

Drug Resistance
Colonic Neoplasms
P-Glycoprotein
Catenins
irinotecan
3 Citations (Scopus)

Synergistic inhibitory effects of cetuximab and curcumin on human cisplatin-resistant oral cancer CAR cells through intrinsic apoptotic process

Chen, C. F., Lu, C. C., Chiang, J. H., Chiu, H. Y., Yang, J. S., Lee, C. Y., Way, T. D. & Huang, H-J., 2018 Nov 1, In : Oncology Letters. 16, 5, p. 6323-6330 8 p.

Research output: Contribution to journalArticle

Curcumin
Mouth Neoplasms
Cisplatin
Epidermal Growth Factor Receptor
Apoptosis

Toll-like receptor 3 is involved in detection of enterovirus a71 infection and targeted by viral 2a protease

Chen, K. R., Yu, C. K., Kung, S. H., Chen, S. H., Chang, C. F., Ho, T. C., Lee, Y. P., Chang, H. C., Huang, L. Y., Lo, S. Y., Chang, J. C. & Ling, P., 2018 Dec 1, In : Viruses. 10, 12, 689.

Research output: Contribution to journalArticle

Toll-Like Receptor 3
Enterovirus Infections
Peptide Hydrolases
Antiviral Agents
Enterovirus
2 Citations (Scopus)

Ursolic acid elicits intrinsic apoptotic machinery by downregulating the phosphorylation of AKT/BAD signaling in human cisplatin-resistant oral cancer CAR cells

Chen, C. F., Yang, J. S., Chen, W. K., Lu, C. C., Chiang, J. H., Chiu, H. Y., Tsai, S. C., Juan, Y. N., Huang, H. J. & Way, T. D., 2018 Sep, In : Oncology Reports. 40, 3, p. 1752-1760 9 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Cisplatin
Down-Regulation
Phosphorylation
B-Cell Lymphoma
2017
2 Citations (Scopus)

Active extracellular substances of Bacillus thuringiensis ITRI-G1 induce microalgae self-disruption for microalgal biofuel

Bai, M. D., Wu, S. I., Chen, C-Y., Chen, J. C., Lu, W. C. & Wan, H. P., 2017 May 1, In : Engineering in Life Sciences. 17, 5, p. 561-566 6 p.

Research output: Contribution to journalArticle

Microalgae
Bacillus thuringiensis
Biofuels
Bacilli
Oils
4 Citations (Scopus)

Characterization of a heat-tolerant Chlorella sp. GD mutant with enhanced photosynthetic CO2 fixation efficiency and its implication as lactic acid fermentation feedstock

Lee, T. M., Tseng, Y. F., Cheng, C. L., Chen, Y. C., Lin, C. S., Su, H. Y., Chow, T. J., Chen, C. Y. & Chang, J. S., 2017 Sep 12, In : Biotechnology for Biofuels. 10, 1, 214.

Research output: Contribution to journalArticle

Chlorella
Lactic acid
Biomass
Fermentation
Feedstocks
4 Citations (Scopus)

Common stress transcriptome analysis reveals functional and genomic architecture differences between early and delayed response genes

Lin, C. W., Huang, L. Y., Huang, C-L., Wang, Y. C., Lai, P. H., Wang, H-V., Chang, W-C., Chiang, T-Y. & Huang, H-J., 2017 Mar 1, In : Plant and Cell Physiology. 58, 3, p. 546-559 14 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
transcriptomics
genomics
Genes
genes
3 Citations (Scopus)

Comparative phylogeography of two codistributed endemic cyprinids in southeastern Taiwan

Chiang, T. Y., Chen, Y. Y., Lee, T. W., Hsu, K. C., Lin, F. J., Wang, W. K. & Lin, H. D., 2017 Feb 1, In : Biochemical Systematics and Ecology. 70, p. 283-290 8 p.

Research output: Contribution to journalArticle

Phylogeography
cyprinid
phylogeography
Taiwan
Fish
9 Citations (Scopus)
Lutein
Nitrates
Acetates
Productivity
Antioxidants
8 Citations (Scopus)

Expression of Synthetic Phytoene Synthase Gene to Enhance β-Carotene Production in Scenedesmus sp. CPC2

Chen, C-Y., Kao, A. L., Tsai, Z. C., Shen, Y. M., Kao, P. H., Ng, I-S. & Chang, J-S., 2017 Nov 1, In : Biotechnology Journal. 12, 11, 1700204.

Research output: Contribution to journalArticle

Scenedesmus
Carotenoids
Genes
Synthetic Genes
phytoene
15 Citations (Scopus)

Feasibility of CO2 mitigation and carbohydrate production by microalga Scenedesmus obliquus CNW-N used for bioethanol fermentation under outdoor conditions: Effects of seasonal changes

Ho, S. H., Chen, Y. D., Chang, C. Y., Lai, Y. Y., Chen, C. Y., Kondo, A., Ren, N. Q. & Chang, J. S., 2017 Jan 31, In : Biotechnology for Biofuels. 10, 1, 27.

Research output: Contribution to journalArticle

Scenedesmus
Bioethanol
microalga
Carbohydrates
Fermentation
1 Citation (Scopus)

Frequent gene flow blurred taxonomic boundaries of sections in Lilium L. (Liliaceae)

Gong, X., Hung, K. H., Ting, Y. W., Hsu, T. W., Malikova, L., Tran, H. T., Huang, C-L., Liu, S. H. & Chiang, T-Y., 2017 Aug 1, In : PloS one. 12, 8, e0183209.

Research output: Contribution to journalArticle

Liliaceae
Lilium
Gene Flow
Expressed Sequence Tags
gene flow

Integrating early transcriptomic responses to rhizotoxins in rice (Oryza sativa. L.) reveals key regulators and a potential early biomarker of cadmium toxicity

Huang, L. Y., Lin, C. W., Lee, R-H., Chiang, C. Y., Wang, Y. C., Chang, C. H. & Huang, H-J., 2017 Aug 8, In : Frontiers in Plant Science. 8, 1432.

Research output: Contribution to journalArticle

transcriptomics
cadmium
biomarkers
Oryza sativa
toxicity
11 Citations (Scopus)
Lutein
Productivity
Mutagenesis
Organic carbon
Lighting
6 Citations (Scopus)

Monocytic thrombomodulin promotes cell adhesion through interacting with its ligand, Lewis y

Lin, W. L., Chen, C. C., Shi, G. Y., Ma, C. Y., Chang, C-F. & Wu, H-L., 2017 Apr 1, In : Immunology and Cell Biology. 95, 4, p. 372-379 8 p.

Research output: Contribution to journalArticle

Thrombomodulin
Cell Adhesion
Ligands
Leukocytes
Endothelium
3 Citations (Scopus)

Overexpression of exogenous kidney-specific Ngal attenuates progressive cyst development and prolongs lifespan in a murine model of polycystic kidney disease

Wang, E., Chiou, Y. Y., Jeng, W. Y., Lin, H. K., Lin, H. H., Chin, H. J., Leo Wang, C. K., Yu, S. S., Tsai, S. C., Chiang, C. Y., Cheng, P. H., Lin, H. J., Jiang, S. T., Chiu, S. T. & Hsieh-Li, H. M., 2017 Feb 1, In : Kidney international. 91, 2, p. 412-422 11 p.

Research output: Contribution to journalArticle

Polycystic Kidney Diseases
Cysts
Kidney
Caspase 3
Transgenic Mice
5 Citations (Scopus)

Serum N-glycome characterization and anti-carbohydrate antibody profiling in oral squamous cell carcinoma patients

Guu, S. Y., Lin, T. H., Chang, S. C., Wang, R. J., Hung, L. Y., Fang, P. J., Tang, W. C., Yu, P. & Chang, C. F., 2017 Jun, In : PloS one. 12, 6, e0178927.

Research output: Contribution to journalArticle

squamous cell carcinoma
Polysaccharides
Anti-Idiotypic Antibodies
Squamous Cell Carcinoma
mouth
Enterovirus
Interleukin-6
Enterovirus Infections
Encephalitis
Viruses
2 Citations (Scopus)

The negative effects of KPN00353 on glycerol kinase and microaerobic 1,3-propanediol production in klebsiella pneumoniae

Jeng, W-Y., Panjaitan, N. S. D., Horng, Y. T., Chung, W. T., Chien, C. C. & Soo, P. C., 2017 Dec 7, In : Frontiers in Microbiology. 8, DEC, 2441.

Research output: Contribution to journalArticle

Glycerol Kinase
Klebsiella pneumoniae
arginine glutamate
Glycerol
Phosphoenolpyruvate
6 Citations (Scopus)

Transcriptome and physiological analysis of a lutein-producing alga Desmodesmus sp. reveals the molecular mechanisms for high lutein productivity

Yeh, T. J., Tseng, Y. F., Chen, Y. C., Hsiao, Y., Lee, P. C., Chen, T. J., Chen, C-Y., Kao, C. Y., Chang, J-S., Chen, J. C. & Lee, T. M., 2017 Jan 1, In : Algal Research. 21, p. 103-119 17 p.

Research output: Contribution to journalArticle

algae
lutein
transcriptome
light harvesting complex
synthesis
2 Citations (Scopus)

Viral infection upregulates myostatin promoter activity in orange-spotted grouper (Epinephelus coioides)

Chen, Y. T., Lin, C. F., Chen, Y. M., Lo, C. E., Chen, W. E. & Chen, T-Y., 2017 Oct 1, In : PloS one. 12, 10, e0186506.

Research output: Contribution to journalArticle

Myostatin
Epinephelus coioides
myostatin
Virus Diseases
Up-Regulation
2016

A member of the immunoglobulin superfamily, orange-spotted grouper novel immune gene EcVig, is induced by immune stimulants and type I interferon

Yeh, Y. C., Wang, T. Y., Chou, H. Y., Lin, H. Y., Chen, T-Y., Aoki, T. & Wang, H-C., 2016 Nov 1, In : Fish and Shellfish Immunology. 58, p. 415-422 8 p.

Research output: Contribution to journalArticle

Epinephelus coioides
Interferon Type I
grouper
interferons
Viruses
7 Citations (Scopus)

Analysis of interferon gamma protein expression in zebrafish (Danio rerio)

Yoon, S., Alnabulsi, A., Wang, T. Y., Lee, P. T., Chen, T-Y., Bird, S., Zou, J. & Secombes, C. J., 2016 Oct 1, In : Fish and Shellfish Immunology. 57, p. 79-86 8 p.

Research output: Contribution to journalArticle

interferon-gamma
Danio rerio
Interferon-gamma
protein synthesis
protein
13 Citations (Scopus)

Comparative transcriptome analysis of Gastrodia elata (Orchidaceae) in response to fungus symbiosis to identify gastrodin biosynthesis-related genes

Tsai, C. C., Wu, K. M., Chiang, T-Y., Huang, C. Y., Chou, C. H., Li, S. J. & Chiang, Y. C., 2016 Mar 9, In : BMC genomics. 17, 1, 212.

Research output: Contribution to journalArticle

Gastrodia
Orchidaceae
Symbiosis
Gene Expression Profiling
Fungi