Chao-Kai Hsu

Associate Professor

  • 967 Citations
  • 15 h-Index
20052022
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Research Output 2005 2019

2019

Adjuvant Radiotherapy After Keloid Excision: Preliminary Experience in Taiwan

Hsueh, W-T., Hung, K. S., Chen, Y. C., Huang, Y. T., Hsu, C-K., Ogawa, R. & Hsueh, Y-Y., 2019 Jan 1, In : Annals of plastic surgery. 82, 1S Suppl 1, p. S39-S44

Research output: Contribution to journalArticle

Keloid
Adjuvant Radiotherapy
Taiwan
Cicatrix
Recurrence

Exertional plantar blistering as an easily overlooked clue for epidermolysis bullosa simplex

Yang, H. S., Yang, C. C., Hsu, C. K., Lee, J., Chao, S. C. & Tu, W. T., 2019 Jul 1, In : Dermatologica Sinica. 37, 3, p. 170-171 2 p.

Research output: Contribution to journalLetter

Open Access

Late-onset comedonal Darier's disease caused by a recurrent ATP2A2 mutation

Guevara, B. E. K., Hou, P. C., Huang, H. Y., Chen, W. R., Wen, Y. K., Chen, W. C., Lee, Y-Y. & Hsu, C-K., 2019 Jun 1, In : Journal of Dermatology. 46, 6, p. e211-e212

Research output: Contribution to journalLetter

Darier Disease
Mutation

Pterygium and thinning of nails as an unusual manifestation in Clouston syndrome

Sukakul, T., Yang, H. S., Onoufriadis, A., Hsu, C-K. & McGrath, J. A., 2019 Jan 1, In : Journal of Dermatology. 46, 9, p. e329-e330

Research output: Contribution to journalLetter

Ectodermal Dysplasia
Pterygium
Nails

Recalcitrant extragenital giant condyloma acuminatum: A need for combination therapy

Lee, C-N., Hsu, C-K. & Lee, Y-Y., 2019 May 1, In : Dermatologic Therapy. 32, 3, e12867.

Research output: Contribution to journalArticle

Buschke-Lowenstein Tumor
Podophyllotoxin
Axilla
imiquimod
Cryotherapy
8 Citations (Scopus)

The Medication Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Asians: The Major Drug Causality and Comparison With the US FDA Label

for the Asian Severe Cutaneous Adverse Reaction Consortium, 2019 Jan 1, In : Clinical Pharmacology and Therapeutics. 105, 1, p. 112-120 9 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
United States Food and Drug Administration
Causality
Pharmaceutical Preparations
terbinafine
5 Citations (Scopus)

The tension biology of wound healing

Harn, H. I. C., Ogawa, R., Hsu, C-K., Hughes, M. W., Tang, M-J. & Chuong, C. M., 2019 Apr 1, In : Experimental Dermatology. 28, 4, p. 464-471 8 p.

Research output: Contribution to journalReview article

Open Access
Wound Healing
Cicatrix
Skin
Keloid
Regeneration

Tumor Endothelial Marker 1 (TEM1/Endosialin/CD248) Enhances Wound Healing by Interacting with Platelet-Derived Growth Factor Receptors

Hong, Y. K., Lee, Y-C., Cheng, T. L., Lai, C-H., Hsu, C-K., Kuo, C. H., Hsu, Y. Y., Li, J. T., Chang, B. I., Ma, C. Y., Lin, S. W., Wang, K. C., Shi, G. Y. & Wu, H-L., 2019 Oct 1, In : Journal of Investigative Dermatology. 139, 10, p. 2204-2214.e7

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Tumor Biomarkers
Wound Healing
Tumors
Fibroblasts
2018
15 Citations (Scopus)

Beneficial effect of ustekinumab in familial pityriasis rubra pilaris with a new missense mutation in CARD14

Lwin, S. M., Hsu, C-K., Liu, L., Huang, H. Y., Levell, N. J. & McGrath, J. A., 2018 Apr 1, In : British Journal of Dermatology. 178, 4, p. 969-972 4 p.

Research output: Contribution to journalArticle

Missense Mutation
Pityriasis Rubra Pilaris
Nuclear Family
Proteins
Palmoplantar Keratoderma
9 Citations (Scopus)

Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts

Hsu, C. K., Lin, H. H., Harn, H. I., Ogawa, R., Wang, Y. K., Ho, Y. T., Chen, W. R., Lee, Y. C., Lee, J. Y. Y., Shieh, S. J., Cheng, C. M., McGrath, J. A. & Tang, M. J., 2018 Jan, In : Journal of Investigative Dermatology. 138, 1, p. 208-218 11 p.

Research output: Contribution to journalArticle

Caveolin 1
Keloid
Fibroblasts
Chemical activation
trichostatin A

Cutaneous lymphomas in Taiwan: A review of 118 cases from a medical center in southern Taiwan

Lee, C. N., Hsu, C-K., Chang, K-C., Wu, C. L., Chen, T-Y. & Lee, Y-Y., 2018 Mar 1, In : Dermatologica Sinica. 36, 1, p. 16-24 9 p.

Research output: Contribution to journalArticle

Mycosis Fungoides
Taiwan
Lymphoma
Skin
Extranodal NK-T-Cell Lymphoma
1 Citation (Scopus)
2 Citations (Scopus)

Homozygous acceptor splice site mutation in DSG1 disrupts plakoglobin localization and results in keratoderma and skin fragility

Lee, J. Y. W., Farag, A., Tawdy, A., Liu, L., Michael, M., Rashidghamat, E., Aristodemou, S., Hsu, C-K., Simpson, M. A., Parsons, M. & McGrath, J. A., 2018 Feb 1, In : Journal of Dermatological Science. 89, 2, p. 198-201 4 p.

Research output: Contribution to journalLetter

Desmoglein 1
gamma Catenin
RNA Splice Sites
Biopsy
Skin
12 Citations (Scopus)

Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis

Tziotzios, C., Lee, J. Y. W., Brier, T., Saito, R., Hsu, C-K., Bhargava, K., Stefanato, C. M., Fenton, D. A. & McGrath, J. A., 2018 Nov 1, In : Journal of the American Academy of Dermatology. 79, 5, p. 789-804 16 p.

Research output: Contribution to journalReview article

Lichen Planus
Skin Diseases
Bryophyta
Continuing Medical Education
Skin
4 Citations (Scopus)

Lichen planus and lichenoid dermatoses: Conventional and emerging therapeutic strategies

Tziotzios, C., Brier, T., Lee, J. Y. W., Saito, R., Hsu, C-K., Bhargava, K., Stefanato, C. M., Fenton, D. A. & McGrath, J. A., 2018 Nov 1, In : Journal of the American Academy of Dermatology. 79, 5, p. 807-818 12 p.

Research output: Contribution to journalReview article

Lichen Planus
Skin Diseases
Continuing Medical Education
Translational Medical Research
Inflammation
12 Citations (Scopus)

Mechanical forces in skin disorders

Hsu, C. K., Lin, H. H., Harn, H. I. C., Hughes, M. W., Tang, M. J. & Yang, C. C., 2018 Jun, In : Journal of Dermatological Science. 90, 3, p. 232-240 9 p.

Research output: Contribution to journalReview article

Skin
Skin Diseases
Wound Healing
Collagen
Epidermolysis Bullosa Simplex
1 Citation (Scopus)

Primary scarring alopecia: A retrospective study of 89 patients in Taiwan

Su, H. J., Cheng, A. Y., Liu, C. H., Chu, C-B., Lee, C-N., Hsu, C-K., Lee, Y-Y. & Yang, C-C., 2018 Apr 1, In : Journal of Dermatology. 45, 4, p. 450-455 6 p.

Research output: Contribution to journalArticle

Alopecia
Taiwan
Cicatrix
Retrospective Studies
Discoid Lupus Erythematosus
2 Citations (Scopus)

Prognostic role of tumoral PDL1 expression and peritumoral FoxP3+ lymphocytes in vulvar melanomas

Chłopik, A., Selim, M. A., Peng, Y., Wu, C. L., Tell-Marti, G., Paral, K. M., Shalin, S. C., Kraft, S., Hsu, C-K., Shea, C. R., Puig, S., Fernandez-Figueras, M. T., Biernat, W., Ryś, J., Marszalek, A. & Hoang, M. P., 2018 Mar 1, In : Human Pathology. 73, p. 176-183 8 p.

Research output: Contribution to journalArticle

Melanoma
Lymphocytes
Survival
Disease-Free Survival
Neoplasms
3 Citations (Scopus)

Time Series Integrative Analysis of RNA Sequencing and MicroRNA Expression Data Reveals Key Biologic Wound Healing Pathways in Keloid-Prone Individuals

Onoufriadis, A., Hsu, C-K., Ainali, C., Ung, C. Y., Rashidghamat, E., Yang, H. S., Huang, H. Y., Niazi, U., Tziotzios, C., Yang, J. C., Nuamah, R., Tang, M-J., Saxena, A., de Rinaldis, E. & McGrath, J. A., 2018 Dec 1, In : Journal of Investigative Dermatology. 138, 12, p. 2690-2693 4 p.

Research output: Contribution to journalArticle

Time series analysis
MicroRNAs
RNA
1 Citation (Scopus)
Paronychia
Betaxolol
Pyogenic Granuloma
Epidermal Growth Factor Receptor
2017
6 Citations (Scopus)

Congenital Anonychia and Uncombable Hair Syndrome: Coinheritance of Homozygous Mutations in RSPO4 and PADI3

Hsu, C. K., Romano, M. T., Nanda, A., Rashidghamat, E., Lee, J. Y. W., Huang, H. Y., Songsantiphap, C., Lee, J. Y. Y., Al-Ajmi, H., Betz, R. C., Simpson, M. A., McGrath, J. A. & Tziotzios, C., 2017 May, In : Journal of Investigative Dermatology. 137, 5, p. 1176-1179 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Further evidence for genotype–phenotype disparity in Griscelli syndrome

Lee, J. Y. W., Eldeeb, M. S., Hsu, C-K., Saito, R., Abouzeid, S. A. & McGrath, J. A., 2017 Apr 1, In : British Journal of Dermatology. 176, 4, p. 1086-1089 4 p.

Research output: Contribution to journalLetter

Genotype
Phenotype
9 Citations (Scopus)

Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23

Lee, J. Y. W., Hsu, C. K., Michael, M., Nanda, A., Liu, L., McMillan, J. R., Pourreyron, C., Takeichi, T., Tolar, J., Reid, E., Hayday, T., Blumen, S. C., Abu-Mouch, S., Straussberg, R., Basel-Vanagaite, L., Barhum, Y., Zouabi, Y., Al-Ajmi, H., Huang, H. Y., Lin, T. C. & 6 others, Akiyama, M., Lee, J. Y. Y., McLean, W. H. I., Simpson, M. A., Parsons, M. & McGrath, J. A., 2017 Feb 2, In : American Journal of Human Genetics. 100, 2, p. 364-370 7 p.

Research output: Contribution to journalArticle

Spastic Paraparesis
Protein-Serine-Threonine Kinases
Protein-Tyrosine Kinases
Pedigree
Keratinocytes
16 Citations (Scopus)

Mutations in KLHL24 Add to the Molecular Heterogeneity of Epidermolysis Bullosa Simplex

Lee, J. Y. W., Liu, L., Hsu, C-K., Aristodemou, S., Ozoemena, L., Ogboli, M., Moss, C., Martinez, A. E., Mellerio, J. E. & McGrath, J. A., 2017 Jun 1, In : Journal of Investigative Dermatology. 137, 6, p. 1378-1380 3 p.

Research output: Contribution to journalArticle

Repressor Proteins
Immunohistochemistry
4 Citations (Scopus)

Novel homozygous missense mutation in NT5C2 underlying hereditary spastic paraplegia SPG45

Straussberg, R., Onoufriadis, A., Konen, O., Zouabi, Y., Cohen, L., Lee, J. Y. W., Hsu, C-K., Simpson, M. A. & McGrath, J. A., 2017 Nov 1, In : American Journal of Medical Genetics, Part A. 173, 11, p. 3109-3113 5 p.

Research output: Contribution to journalArticle

Hereditary Spastic Paraplegia
Missense Mutation
Mutation
Exome
Islam
2 Citations (Scopus)

PLACK syndrome resulting from a new homozygous insertion mutation in CAST

Alkhalifah, A., Chiaverini, C., Del Giudice, P., Supsrisunjai, C., Hsu, C-K., Liu, L., Charlesworth, A., McGrath, J. A. & Lacour, J. P., 2017 Nov 1, In : Journal of Dermatological Science. 88, 2, p. 256-258 3 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Predictive phenotyping of inherited ichthyosis by next-generation DNA sequencing

Saito, R., Boyce, A., Hsu, C-K., Rashidghamat, E., Hide, M., Wedgeworth, E. K., Flohr, C., Mellerio, J. E. & McGrath, J. A., 2017 Jan 1, In : British Journal of Dermatology. 176, 1, p. 249-251 3 p.

Research output: Contribution to journalLetter

39 Citations (Scopus)

Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians

For the Taiwan Severe Cutaneous Adverse Reaction Consortium, 2017 Jan 3, In : Neurology. 88, 1, p. 78-86 9 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
HLA-B15 Antigen
Skin
Carbamazepine
Taiwan
7 Citations (Scopus)

Syndromic inherited poikiloderma due to a de novo mutation in FAM111B

Takeichi, T., Nanda, A., Yang, H. S., Hsu, C-K., Lee, Y-Y., Al-Ajmi, H., Akiyama, M., Simpson, M. A. & McGrath, J. A., 2017 Feb 1, In : British Journal of Dermatology. 176, 2, p. 534-536 3 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Systematised naevus sebaceus resulting from post-zygotic mutation in HRAS

Hsu, C-K., Saito, R., Nanda, A., Rashidghamat, E., Al-Ajmi, H., Lee, Y-Y., Hide, M. & McGrath, J. A., 2017 Feb 1, In : Australasian Journal of Dermatology. 58, 1, p. 58-60 3 p.

Research output: Contribution to journalArticle

Nevus
Mutation
Newborn Infant
Skin
DNA
2016

Ectodermal dysplasia–skin fragility syndrome resulting from a new atypical homozygous cryptic acceptor splice site mutation in PKP1

Hsu, C-K., Liu, L., Can, P. K., Kocatürk, E., McMillan, J. R., Güngör, Ş., Hürdoğan, Ö., Sargan, A., Degirmentepe, E. N., Lee, J. Y. W., Simpson, M. A. & McGrath, J. A., 2016 Nov 1, In : Journal of Dermatological Science. 84, 2, p. 210-212 3 p.

Research output: Contribution to journalLetter

Erythrokeratoderma variabilis caused by p.Gly45Glu in connexin 31: Importance of the first extracellular loop glycine residue for gap junction function

Takeichi, T., Sugiura, K., Hsu, C-K., Nomura, T., Takama, H., Simpson, M. A., Shimizu, H., McGrath, J. A. & Akiyama, M., 2016 Jan 1, In : Acta Dermato-Venereologica. 96, 4, p. 557-559 3 p.

Research output: Contribution to journalComment/debate

DNA Mutational Analysis
Erythrokeratodermia Variabilis
Connexin 43
Protein Conformation
Gap Junctions
1 Citation (Scopus)

Ichthyosis prematurity syndrome: From fetus to adulthood

Lwin, S. M., Hsu, C-K., McMillan, J. R., Mellerio, J. E. & McGrath, J. A., 2016 Sep 1, In : JAMA Dermatology. 152, 9, p. 1055-1058 4 p.

Research output: Contribution to journalLetter

Fetus
Ichthyosis prematurity syndrome
2 Citations (Scopus)

Improved molecular diagnosis of the common recurrent intragenic deletion mutation in IKBKG in a Filipino family with incontinentia pigmenti

Guevara, B. E. K., Hsu, C-K., Liu, L., Feast, A., Alabado, K. L. P., Lacuesta, M. P. M., Lee, Y-Y. & McGrath, J. A., 2016 May 1, In : Australasian Journal of Dermatology. 57, 2, p. 150-153 4 p.

Research output: Contribution to journalArticle

Incontinentia Pigmenti
Sequence Deletion
Siblings
Exons
Polymerase Chain Reaction
3 Citations (Scopus)

Incontinentia pigmenti in a father and daughter

Rashidghamat, E., Hsu, C. K., Nanda, A., Liu, L., Al-Ajmi, H. & McGrath, J. A., 2016 Jan 1, In : British Journal of Dermatology. 175, 5, p. 1059-1060 2 p.

Research output: Contribution to journalLetter

I-kappa B Kinase
Incontinentia Pigmenti
Mosaicism
Gene Deletion
Genetic Predisposition to Disease

Mechanobiology and Mechanotherapy for Skin Disorders

Hsu, C-K. & Ogawa, R., 2016 Nov 7, Mechanobiology: Exploitation for Medical Benefit. wiley, p. 221-237 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biophysics
Skin
Cutis Laxa
Skin Ulcer
Ehlers-Danlos Syndrome

Pigmented hidroacanthoma simplex of the scalp mimicking clonal seborrheic keratosis

Hsu, T. C., Liu, C. H., Hsu, C-K., Wong, T-W. & Lee, Y-Y., 2016 Mar 1, In : Dermatologica Sinica. 34, 1, p. 64-65 2 p.

Research output: Contribution to journalLetter

Seborrheic Keratosis
Scalp
2 Citations (Scopus)

Portable handheld diffuse reflectance spectroscopy system for clinical evaluation of skin: A pilot study in psoriasis patients

Tzeng, S. Y., Guo, J. Y., Yang, C-C., Hsu, C-K., Huang, H. J., Chou, S. J., Hwang, C. H. & Tseng, S-H., 2016 Jan 21, In : Biomedical Optics Express. 7, 2, p. 616-628 13 p., 254728.

Research output: Contribution to journalArticle

Psoriasis
Spectrum Analysis
reflectance
Skin
evaluation
2 Citations (Scopus)

Spatial distribution of filament elasticity determines the migratory behaviors of a cell

Harn, H. I. C., Hsu, C-K., Wang, Y-G., Huang, Y. W., Chiu, W-T., Lin, H. H., Cheng, C. M. & Tang, M-J., 2016 Jul 3, In : Cell Adhesion and Migration. 10, 4, p. 368-377 10 p.

Research output: Contribution to journalArticle

Elasticity
Actin Cytoskeleton
Focal Adhesions
Atomic Force Microscopy
Research
4 Citations (Scopus)

Toward reliable retrieval of functional information of papillary dermis using spatially resolved diffuse reflectance spectroscopy

Chen, Y. W., Guo, J. Y., Tzeng, S. Y., Chou, T. C., Lin, M. J., Huang, L. L-H., Yang, C-C., Hsu, C-K. & Tseng, S-H., 2016 Jan 19, In : Biomedical Optics Express. 7, 2, p. 542-558 17 p., 252734.

Research output: Contribution to journalArticle

Information Storage and Retrieval
Dermis
retrieval
Spectrum Analysis
reflectance
2015

Bowen's disease with features resembling myrmecia wart

Hsu, C-K., Chen, Y. C., Yang, W. L., Hsu, K-F., Chao, S-C. & Lee, Y-Y., 2015 Jan 1, In : Journal of Dermatology. 42, 1, p. 90-93 4 p.

Research output: Contribution to journalArticle

Bowen's Disease
Warts
Papillomavirus Infections
Keratinocytes
Electron Microscopy
4 Citations (Scopus)
Lighting
spectrum analysis
broadband
Skin
illumination
1 Citation (Scopus)

Conjunctival geographic ulcer: An overlooked sign of herpes simplex virus infection

Hung, J-H., Chu, C. Y., Lee, C. N., Hsu, C-K., Lee, Y-Y., Wang, J-R., Chang, K-C. & Huang, F-C., 2015 Mar 1, In : Journal of Clinical Virology. 64, p. 40-44 5 p.

Research output: Contribution to journalArticle

Virus Diseases
Simplexvirus
Ulcer
Blepharitis
Corneal Ulcer
1 Citation (Scopus)

Excimer lamp as an effective alternative treatment for severe alopecia areata

Hsu, T. C., Lin, T. K., Hsu, C-K., Jou, H. J. & Yang, C-C., 2015 Jan 1, In : Dermatologica Sinica. 33, 3, p. 151-153 3 p.

Research output: Contribution to journalArticle

Alopecia Areata
Therapeutics
Therapeutic Uses
2 Citations (Scopus)

Insect bite-like reaction in association with chronic lymphocytic leukemia

Liu, K. C., Hsu, C-K. & Lee, Y-Y., 2015 Oct 1, In : International Journal of Dermatology. 54, 10, p. 1191-1193 3 p.

Research output: Contribution to journalArticle

Vesiculobullous Skin Diseases
Insect Bites and Stings
B-Cell Chronic Lymphocytic Leukemia
14 Citations (Scopus)

Mechanical coupling of cytoskeletal elasticity and force generation is crucial for understanding the migrating nature of keloid fibroblasts

Harn, H. I. C., Wang, Y. K., Hsu, C. K., Ho, Y. T., Huang, Y. W., Chiu, W. T., Lin, H. H., Cheng, C. M. & Tang, M. J., 2015 Aug 1, In : Experimental Dermatology. 24, 8, p. 579-584 6 p.

Research output: Contribution to journalArticle

Keloid
Elasticity
Fibroblasts
Spatial distribution
Actins
13 Citations (Scopus)

Non-invasive evaluation of therapeutic response in keloid scar using diffuse reflectance spectroscopy

Hsu, C-K., Tzeng, S. Y., Yang, C-C., Lee, Y-Y., Huang, L. L-H., Chen, W. R., Hughes, M. W., Chen, Y. W., Liao, Y. K. & Tseng, S-H., 2015 Jan 1, In : Biomedical Optics Express. 6, 2, p. 390-404 15 p.

Research output: Contribution to journalArticle

Keloid
scars
Cicatrix
Spectrum Analysis
reflectance
3 Citations (Scopus)

Novel indel mutation of STS underlies a new phenotype of self-healing recessive X-linked ichthyosis

Takeichi, T., Sugiura, K., Hsu, C. K., Tanahashi, K., Takama, H., Simpson, M. A., McGrath, J. A. & Akiyama, M., 2015 Sep, In : Journal of Dermatological Science. 79, 3, p. 317-319 3 p.

Research output: Contribution to journalLetter

Steryl-Sulfatase

Primäre humane Demodikose: Eine Erkrankung sui generis

Translated title of the contribution: Primary human demodicosis: A disease sui generisHsu, C-K., Zink, A., Wei, K. J., Dzika, E., Plewig, G. & Chen, W., 2015 Mar 19, In : Hautarzt. 66, 3, p. 189-194 6 p.

Research output: Contribution to journalReview article

Mites
Skin Diseases
Perioral Dermatitis
Acaricides
Folliculitis