Chao-Kai Hsu

Associate Professor

  • 931 Citations
  • 15 h-Index
20052022
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Research Output 2005 2019

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Article
2019

Adjuvant Radiotherapy After Keloid Excision: Preliminary Experience in Taiwan

Hsueh, W-T., Hung, K. S., Chen, Y. C., Huang, Y. T., Hsu, C-K., Ogawa, R. & Hsueh, Y-Y., 2019 Jan 1, In : Annals of plastic surgery. 82, 1S Suppl 1, p. S39-S44

Research output: Contribution to journalArticle

Keloid
Adjuvant Radiotherapy
Taiwan
Cicatrix
Recurrence

Recalcitrant extragenital giant condyloma acuminatum: A need for combination therapy

Lee, C-N., Hsu, C-K. & Lee, Y-Y., 2019 May 1, In : Dermatologic Therapy. 32, 3, e12867.

Research output: Contribution to journalArticle

Buschke-Lowenstein Tumor
Podophyllotoxin
Axilla
imiquimod
Cryotherapy
7 Citations (Scopus)

The Medication Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Asians: The Major Drug Causality and Comparison With the US FDA Label

for the Asian Severe Cutaneous Adverse Reaction Consortium, 2019 Jan 1, In : Clinical Pharmacology and Therapeutics. 105, 1, p. 112-120 9 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
United States Food and Drug Administration
Causality
Pharmaceutical Preparations
terbinafine

Tumor Endothelial Marker 1 (TEM1/Endosialin/CD248) Enhances Wound Healing by Interacting with Platelet-Derived Growth Factor Receptors

Hong, Y. K., Lee, Y-C., Cheng, T. L., Lai, C-H., Hsu, C-K., Kuo, C. H., Hsu, Y. Y., Li, J. T., Chang, B. I., Ma, C. Y., Lin, S. W., Wang, K. C., Shi, G. Y. & Wu, H-L., 2019 Jan 1, In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

Platelet-Derived Growth Factor Receptors
Tumor Biomarkers
Wound Healing
Tumors
Fibroblasts
2018
15 Citations (Scopus)

Beneficial effect of ustekinumab in familial pityriasis rubra pilaris with a new missense mutation in CARD14

Lwin, S. M., Hsu, C-K., Liu, L., Huang, H. Y., Levell, N. J. & McGrath, J. A., 2018 Apr 1, In : British Journal of Dermatology. 178, 4, p. 969-972 4 p.

Research output: Contribution to journalArticle

Missense Mutation
Pityriasis Rubra Pilaris
Nuclear Family
Proteins
Palmoplantar Keratoderma
7 Citations (Scopus)

Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts

Hsu, C-K., Lin, H. H., Harn, H. I., Ogawa, R., Wang, Y-G., Ho, Y. T., Chen, W. R., Lee, Y. C., Lee, Y-Y., Shieh, S-J., Cheng, C. M., McGrath, J. A. & Tang, M-J., 2018 Jan 1, In : Journal of Investigative Dermatology. 138, 1, p. 208-218 11 p.

Research output: Contribution to journalArticle

Caveolin 1
Keloid
Fibroblasts
Chemical activation
trichostatin A

Cutaneous lymphomas in Taiwan: A review of 118 cases from a medical center in southern Taiwan

Lee, C. N., Hsu, C-K., Chang, K-C., Wu, C. L., Chen, T-Y. & Lee, Y-Y., 2018 Mar 1, In : Dermatologica Sinica. 36, 1, p. 16-24 9 p.

Research output: Contribution to journalArticle

Mycosis Fungoides
Taiwan
Lymphoma
Skin
Extranodal NK-T-Cell Lymphoma
1 Citation (Scopus)
1 Citation (Scopus)

Primary scarring alopecia: A retrospective study of 89 patients in Taiwan

Su, H. J., Cheng, A. Y., Liu, C. H., Chu, C-B., Lee, C-N., Hsu, C-K., Lee, Y-Y. & Yang, C-C., 2018 Apr 1, In : Journal of Dermatology. 45, 4, p. 450-455 6 p.

Research output: Contribution to journalArticle

Alopecia
Taiwan
Cicatrix
Retrospective Studies
Discoid Lupus Erythematosus
1 Citation (Scopus)

Prognostic role of tumoral PDL1 expression and peritumoral FoxP3+ lymphocytes in vulvar melanomas

Chłopik, A., Selim, M. A., Peng, Y., Wu, C. L., Tell-Marti, G., Paral, K. M., Shalin, S. C., Kraft, S., Hsu, C-K., Shea, C. R., Puig, S., Fernandez-Figueras, M. T., Biernat, W., Ryś, J., Marszalek, A. & Hoang, M. P., 2018 Mar 1, In : Human Pathology. 73, p. 176-183 8 p.

Research output: Contribution to journalArticle

Melanoma
Lymphocytes
Survival
Disease-Free Survival
Neoplasms
3 Citations (Scopus)

Time Series Integrative Analysis of RNA Sequencing and MicroRNA Expression Data Reveals Key Biologic Wound Healing Pathways in Keloid-Prone Individuals

Onoufriadis, A., Hsu, C-K., Ainali, C., Ung, C. Y., Rashidghamat, E., Yang, H. S., Huang, H. Y., Niazi, U., Tziotzios, C., Yang, J. C., Nuamah, R., Tang, M-J., Saxena, A., de Rinaldis, E. & McGrath, J. A., 2018 Dec 1, In : Journal of Investigative Dermatology. 138, 12, p. 2690-2693 4 p.

Research output: Contribution to journalArticle

Time series analysis
MicroRNAs
RNA
1 Citation (Scopus)
Paronychia
Betaxolol
Pyogenic Granuloma
Epidermal Growth Factor Receptor
2017
6 Citations (Scopus)

Congenital Anonychia and Uncombable Hair Syndrome: Coinheritance of Homozygous Mutations in RSPO4 and PADI3

Hsu, C-K., Romano, M. T., Nanda, A., Rashidghamat, E., Lee, J. Y. W., Huang, H. Y., Songsantiphap, C., Lee, Y-Y., Al-Ajmi, H., Betz, R. C., Simpson, M. A., McGrath, J. A. & Tziotzios, C., 2017 May 1, In : Journal of Investigative Dermatology. 137, 5, p. 1176-1179 4 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23

Lee, J. Y. W., Hsu, C-K., Michael, M., Nanda, A., Liu, L., McMillan, J. R., Pourreyron, C., Takeichi, T., Tolar, J., Reid, E., Hayday, T., Blumen, S. C., Abu-Mouch, S., Straussberg, R., Basel-Vanagaite, L., Barhum, Y., Zouabi, Y., Al-Ajmi, H., Huang, H. Y., Lin, T. C. & 6 others, Akiyama, M., Lee, Y-Y., McLean, W. H. I., Simpson, M. A., Parsons, M. & McGrath, J. A., 2017 Feb 2, In : American Journal of Human Genetics. 100, 2, p. 364-370 7 p.

Research output: Contribution to journalArticle

Spastic Paraparesis
Protein-Serine-Threonine Kinases
Protein-Tyrosine Kinases
Pedigree
Keratinocytes
15 Citations (Scopus)

Mutations in KLHL24 Add to the Molecular Heterogeneity of Epidermolysis Bullosa Simplex

Lee, J. Y. W., Liu, L., Hsu, C-K., Aristodemou, S., Ozoemena, L., Ogboli, M., Moss, C., Martinez, A. E., Mellerio, J. E. & McGrath, J. A., 2017 Jun 1, In : Journal of Investigative Dermatology. 137, 6, p. 1378-1380 3 p.

Research output: Contribution to journalArticle

Repressor Proteins
Immunohistochemistry
4 Citations (Scopus)

Novel homozygous missense mutation in NT5C2 underlying hereditary spastic paraplegia SPG45

Straussberg, R., Onoufriadis, A., Konen, O., Zouabi, Y., Cohen, L., Lee, J. Y. W., Hsu, C-K., Simpson, M. A. & McGrath, J. A., 2017 Nov 1, In : American Journal of Medical Genetics, Part A. 173, 11, p. 3109-3113 5 p.

Research output: Contribution to journalArticle

Hereditary Spastic Paraplegia
Missense Mutation
Mutation
Exome
Islam
35 Citations (Scopus)

Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians

For the Taiwan Severe Cutaneous Adverse Reaction Consortium, 2017 Jan 3, In : Neurology. 88, 1, p. 78-86 9 p.

Research output: Contribution to journalArticle

Stevens-Johnson Syndrome
HLA-B15 Antigen
Skin
Carbamazepine
Taiwan
1 Citation (Scopus)

Systematised naevus sebaceus resulting from post-zygotic mutation in HRAS

Hsu, C-K., Saito, R., Nanda, A., Rashidghamat, E., Al-Ajmi, H., Lee, Y-Y., Hide, M. & McGrath, J. A., 2017 Feb 1, In : Australasian Journal of Dermatology. 58, 1, p. 58-60 3 p.

Research output: Contribution to journalArticle

Nevus
Mutation
Newborn Infant
Skin
DNA
2016
2 Citations (Scopus)

Improved molecular diagnosis of the common recurrent intragenic deletion mutation in IKBKG in a Filipino family with incontinentia pigmenti

Guevara, B. E. K., Hsu, C-K., Liu, L., Feast, A., Alabado, K. L. P., Lacuesta, M. P. M., Lee, Y-Y. & McGrath, J. A., 2016 May 1, In : Australasian Journal of Dermatology. 57, 2, p. 150-153 4 p.

Research output: Contribution to journalArticle

Incontinentia Pigmenti
Sequence Deletion
Siblings
Exons
Polymerase Chain Reaction
2 Citations (Scopus)

Portable handheld diffuse reflectance spectroscopy system for clinical evaluation of skin: A pilot study in psoriasis patients

Tzeng, S. Y., Guo, J. Y., Yang, C-C., Hsu, C-K., Huang, H. J., Chou, S. J., Hwang, C. H. & Tseng, S-H., 2016 Jan 21, In : Biomedical Optics Express. 7, 2, p. 616-628 13 p., 254728.

Research output: Contribution to journalArticle

Psoriasis
Spectrum Analysis
reflectance
Skin
evaluation
2 Citations (Scopus)

Spatial distribution of filament elasticity determines the migratory behaviors of a cell

Harn, H. I. C., Hsu, C-K., Wang, Y-G., Huang, Y. W., Chiu, W-T., Lin, H. H., Cheng, C. M. & Tang, M-J., 2016 Jul 3, In : Cell Adhesion and Migration. 10, 4, p. 368-377 10 p.

Research output: Contribution to journalArticle

Elasticity
Actin Cytoskeleton
Focal Adhesions
Atomic Force Microscopy
Research
4 Citations (Scopus)

Toward reliable retrieval of functional information of papillary dermis using spatially resolved diffuse reflectance spectroscopy

Chen, Y. W., Guo, J. Y., Tzeng, S. Y., Chou, T. C., Lin, M. J., Huang, L. L-H., Yang, C-C., Hsu, C-K. & Tseng, S-H., 2016 Jan 19, In : Biomedical Optics Express. 7, 2, p. 542-558 17 p., 252734.

Research output: Contribution to journalArticle

Information Storage and Retrieval
Dermis
retrieval
Spectrum Analysis
reflectance
2015

Bowen's disease with features resembling myrmecia wart

Hsu, C-K., Chen, Y. C., Yang, W. L., Hsu, K-F., Chao, S-C. & Lee, Y-Y., 2015 Jan 1, In : Journal of Dermatology. 42, 1, p. 90-93 4 p.

Research output: Contribution to journalArticle

Bowen's Disease
Warts
Papillomavirus Infections
Keratinocytes
Electron Microscopy
4 Citations (Scopus)
Lighting
spectrum analysis
broadband
Skin
illumination
1 Citation (Scopus)

Conjunctival geographic ulcer: An overlooked sign of herpes simplex virus infection

Hung, J-H., Chu, C. Y., Lee, C. N., Hsu, C-K., Lee, Y-Y., Wang, J-R., Chang, K-C. & Huang, F-C., 2015 Mar 1, In : Journal of Clinical Virology. 64, p. 40-44 5 p.

Research output: Contribution to journalArticle

Virus Diseases
Simplexvirus
Ulcer
Blepharitis
Corneal Ulcer

Excimer lamp as an effective alternative treatment for severe alopecia areata

Hsu, T. C., Lin, T. K., Hsu, C-K., Jou, H. J. & Yang, C-C., 2015 Jan 1, In : Dermatologica Sinica. 33, 3, p. 151-153 3 p.

Research output: Contribution to journalArticle

Alopecia Areata
Therapeutics
Therapeutic Uses
2 Citations (Scopus)

Insect bite-like reaction in association with chronic lymphocytic leukemia

Liu, K. C., Hsu, C-K. & Lee, Y-Y., 2015 Oct 1, In : International Journal of Dermatology. 54, 10, p. 1191-1193 3 p.

Research output: Contribution to journalArticle

Vesiculobullous Skin Diseases
Insect Bites and Stings
B-Cell Chronic Lymphocytic Leukemia
14 Citations (Scopus)

Mechanical coupling of cytoskeletal elasticity and force generation is crucial for understanding the migrating nature of keloid fibroblasts

Harn, H. I. C., Wang, Y-G., Hsu, C-K., Ho, Y. T., Huang, Y. W., Chiu, W-T., Lin, H. H., Cheng, C. M. & Tang, M-J., 2015 Aug 1, In : Experimental Dermatology. 24, 8, p. 579-584 6 p.

Research output: Contribution to journalArticle

Keloid
Elasticity
Fibroblasts
Spatial distribution
Actins
13 Citations (Scopus)

Non-invasive evaluation of therapeutic response in keloid scar using diffuse reflectance spectroscopy

Hsu, C-K., Tzeng, S. Y., Yang, C-C., Lee, Y-Y., Huang, L. L-H., Chen, W. R., Hughes, M. W., Chen, Y. W., Liao, Y. K. & Tseng, S-H., 2015 Jan 1, In : Biomedical Optics Express. 6, 2, p. 390-404 15 p.

Research output: Contribution to journalArticle

Keloid
scars
Cicatrix
Spectrum Analysis
reflectance
10 Citations (Scopus)

Progressive hyperpigmentation in a Taiwanese child due to an inborn error of vitamin B12 metabolism (cblJ)

Takeichi, T., Hsu, C-K., Yang, H. S., Chen, H. Y., Wong, T-W., Tsai, W. L., Chao, S. C., Lee, Y-Y., Akiyama, M., Simpson, M. A. & McGrath, J. A., 2015 Apr 1, In : British Journal of Dermatology. 172, 4, p. 1111-1115 5 p.

Research output: Contribution to journalArticle

Hyperpigmentation
Vitamin B 12
Mutation
Skin
Homocystinuria
9 Citations (Scopus)

Thrombomodulin promotes diabetic wound healing by regulating toll-like receptor 4 expression

Cheng, T. L., Lai, C-H., Chen, P. K., Cho, C. F., Hsu, Y. Y., Wang, K. C., Lin, W. L., Chang, B. I., Liu, S. K., Wu, Y. T., Hsu, C-K., Shi, G. Y. & Wu, H-L., 2015 Jan 1, In : Journal of Investigative Dermatology. 135, 6, p. 1668-1675 8 p.

Research output: Contribution to journalArticle

Thrombomodulin
Toll-Like Receptor 4
Keratinocytes
Wound Healing
Glucose
2014
119 Citations (Scopus)

Genetic variants associated with phenytoin-related severe cutaneous adverse reactions

Chung, W. H., Chang, W. C., Lee, Y. S., Wu, Y. Y., Yang, C. H., Ho, H. C., Chen, M. J., Lin, J. Y., Hui, R. C. Y., Ho, J. C., Wu, W. M., Chen, T. J., Wu, T., Wu, Y. R., Hsih, M. S., Tu, P. H., Chang, C. N., Hsu, C. N., Wu, T. L., Choon, S. E. & 16 others, Hsu, C-K., Chen, D. Y., Liu, C. S., Lin, C. Y., Kaniwa, N., Saito, Y., Takahashi, Y., Nakamura, R., Azukizawa, H., Shi, Y., Wang, T. H., Chuang, S. S., Tsai, S. F., Chang, C. J., Chang, Y. S. & Hung, S. I., 2014 Jan 1, In : JAMA - Journal of the American Medical Association. 312, 5, p. 525-535 11 p.

Research output: Contribution to journalArticle

Phenytoin
Skin
Taiwan
Population Control
Stevens-Johnson Syndrome
21 Citations (Scopus)
Alopecia
Taiwan
Body Mass Index
Cross-Sectional Studies
Obesity
1 Citation (Scopus)

Lymphomatoid papulosis in association with mycosis fungoides: A clinical and histopathologic review of five Taiwanese cases

Huang, C. H., Hsu, C-K. & Lee, Y-Y., 2014 Jan 1, In : Dermatologica Sinica. 32, 2, p. 75-81 7 p.

Research output: Contribution to journalArticle

Lymphomatoid Papulosis
Mycosis Fungoides
Skin
Lymphoma
Biopsy
60 Citations (Scopus)

Paper-based ELISA for the detection of autoimmune antibodies in body fluid-the case of bullous pemphigoid

Hsu, C-K., Huang, H. Y., Chen, W. R., Nishie, W., Ujiie, H., Natsuga, K., Fan, S. T., Wang, H. K., Lee, Y-Y., Tsai, W. L., Shimizu, H. & Cheng, C. M., 2014 May 6, In : Analytical Chemistry. 86, 9, p. 4605-4610 6 p.

Research output: Contribution to journalArticle

Immunosorbents
Body fluids
Assays
Antibodies
Enzymes
7 Citations (Scopus)

Rapid detection of dermatophytes and Candida albicans in onychomycosis specimens by an oligonucleotide array

Han, H. W., Hsu, M. M. L., Choi, J. S., Hsu, C-K., Hsieh, H. Y., Li, H. C., Chang, H-C. & Chang, T. C., 2014 Nov 7, In : BMC Infectious Diseases. 14, 1, 581.

Research output: Contribution to journalArticle

Onychomycosis
Arthrodermataceae
Oligonucleotide Array Sequence Analysis
Candida albicans
Nails
3 Citations (Scopus)

Recurrent Scedosporium apiospermum mycetoma successfully treated by surgical excision and voriconazole

Chiang, C. H., Hsu, C-K., Lee, Y-Y., Chang, T. C., Hsueh, Y-Y., Shieh, S-J., Chen, H. M. & Hsu, M. M. L., 2014 Mar 1, In : Dermatologica Sinica. 32, 1, p. 29-32 4 p.

Research output: Contribution to journalArticle

Scedosporium
Mycetoma
Fungi
Intralesional Injections
Skin
23 Citations (Scopus)

Treatment of hereditary epidermolysis bullosa: Updates and future prospects

Hsu, C-K., Wang, S. P., Lee, Y-Y. & McGrath, J. A., 2014 Feb 1, In : American Journal of Clinical Dermatology. 15, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Epidermolysis Bullosa
Skin Diseases
Epidermolysis Bullosa Dystrophica
Biomedical Engineering
Pluripotent Stem Cells
2013
2 Citations (Scopus)
Amelanotic Melanoma
Melanoma
Melanocytes
Neoplasms
Epidermis
11 Citations (Scopus)

Early intervention with high-dose steroid pulse therapy prolongs disease-free interval of severe alopecia areata: A retrospective study

Yang, C-C., Lee, C. T., Hsu, C-K., Lee, Y. P., Wong, T-W., Chao, S-C., Lee, Y-Y., Sheu, H. M. & Chen, W. C., 2013 Nov 1, In : Annals of Dermatology. 25, 4, p. 471-474 4 p.

Research output: Contribution to journalArticle

Alopecia Areata
Retrospective Studies
Steroids
Alopecia
Therapeutics
10 Citations (Scopus)
Azepines
Amyloid Precursor Protein Secretases
Psoriasis
Alanine
Alzheimer Disease
2 Citations (Scopus)

The evolution of clinicopathologic features in eruptive lichen planus: A case report and review of literature

Liu, K. C., Lee, Y-Y., Hsu, M. M. L. & Hsu, C-K., 2013 Jan 1, In : Dermatology Online Journal. 19, 1, 1 p.

Research output: Contribution to journalArticle

Lichen Planus
Prednisolone
Inflammation
Skin
2012
41 Citations (Scopus)
Adult-Onset Still's Disease
Dermatomyositis
Exanthema
Prurigo
Lymphocytes
19 Citations (Scopus)
Lupus Erythematosus Panniculitis
Alopecia
Scalp
Mucins
Hydroxychloroquine

Lipodystrophia centrifugalis abdominalis infantilis: Report of four cases

Wu, M. C., Hsu, C-K. & Lee, Y-Y., 2012 May 1, In : Pediatric Dermatology. 29, 3, p. 308-310 3 p.

Research output: Contribution to journalArticle

Groin
Abdomen
Skin
25 Citations (Scopus)
scars
Hemoglobin
hemoglobin
collagens
Collagen
2 Citations (Scopus)
Human Milk
Zinc
Breast
Genes
Zinc Sulfate
2009
28 Citations (Scopus)

Analysis of Taiwanese ichthyosis vulgaris families further demonstrates differences in FLG mutations between European and Asian populations

Hsu, C-K., Akiyama, M., Nemoto-Hasebe, I., Nomura, T., Sandilands, A., Chao, S-C., Lee, Y-Y., Sheu, H. M., McLean, W. H. I. & Shimizu, H., 2009 Dec 1, In : British Journal of Dermatology. 161, 2, p. 448-451 4 p.

Research output: Contribution to journalArticle

Ichthyosis Vulgaris
Mutation
Population
Population Genetics
filaggrin
9 Citations (Scopus)

Clinicopathological study of Fox-Fordyce disease

Kao, P. H., Hsu, C-K. & Lee, Y-Y., 2009 Sep 1, In : Journal of Dermatology. 36, 9, p. 485-490 6 p.

Research output: Contribution to journalArticle

Fox-Fordyce Disease
Apocrine Glands
Pituitary Gland
Syringoma
Neurodermatitis