Chi-Wu Chiang

Personal profile

Education

1998 PhD, Department of Biology and Division of Geographic Medicine University of Alabama at Birmingham,USA

Research Interests

Protein phosphatase
Signal transduction
Tumor biology
訊息傳遞

Experience

1992-1993 Research assistant, Dr. Chen-Kung Chou’s lab Endocrinology Laboratory, Taipei Veterans General Hospital, Taiwan. Studies on the regulation of Hepatitis B Virus gene expression by retinoids
1993-1998 Graduate assistant, Department of Biology and Division of Geographic Medicine University of Alabama at Birmingham Birmingham, Alabama, U.S.A.
1998-2003 Postdoctoral Research Fellow, Department of Pediatrics and Vanderbilt-Ingram Cancer center, Vanderbilt University, Nashville, TN, U.S.A.
2003~2010 Assistant Professor, Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan
2010-present Associate Professor, Institute of Molecular Medicine, National Cheng Kung University Medical College

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2 Similar Profiles

Protein Phosphatase 2 Medicine & Life Sciences

Apoptosis Medicine & Life Sciences

Phosphorylation Medicine & Life Sciences

Phosphoprotein Phosphatases Medicine & Life Sciences

Cell proliferation Chemical Compounds

Caspase 2 Medicine & Life Sciences

Vidarabine Medicine & Life Sciences

Adenosine Kinase Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2004 2017

9 Finished

探討PP2A-B56γ3調控p70S6K1及p70S6K1調節的負回饋環路及其在大腸癌轉移的角色

Chiang, C.

16-08-01 → 17-07-31

Project: Research project

探討磷酸水解?PP2A-B56gamma 3複合體位於酪蛋白激?及腺?單磷酸活化激?下游的調節機制及在細胞中的角色

Chiang, C.

13-08-01 → 14-07-31

Project: Research project

功能性分析磷酸酵素PP2A 的B56 gamma 3調節次單元的抑癌機制

Chiang, C.

09-08-01 → 10-07-31

Project: Research project

功能性分析磷酸酵素PP2A 的B56 gamma 3調節次單元的抑癌機制

Chiang, C.

08-08-01 → 09-07-31

Project: Research project

功能性分析磷酸酵素PP2A 的B56 gamma 3調節次單元的抑癌機制

Chiang, C.

07-08-01 → 08-07-31

Project: Research project

Research Output 1999 2019

1027 Citations
15 h-Index
26 Article
1 Chapter
1 Comment/debate
1 Review article

1 Citation (Scopus)

A novel proteotoxic combination therapy for EGFR+ and HER2+ cancers

Wang, M., Ferreira, R. B., Law, M. E., Davis, B. J., Yaaghubi, E., Ghilardi, A. F., Sharma, A., Avery, B. A., Rodriguez, E., Chiang, C-W., Narayan, S., Heldermon, C. D., Castellano, R. K. & Law, B. K., 2019 May 30, In : Oncogene. 38, 22, p. 4264-4282 19 p.

Research output: Contribution to journal › Article

Disulfides

Neoplasms

Cyclosporine

Protein Folding

Therapeutics

Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway

Wang, M., Law, M. E., Davis, B. J., Yaaghubi, E., Ghilardi, A. F., Ferreira, R. B., Chiang, C. W., Guryanova, O. A., Kopinke, D., Heldermon, C. D., Castellano, R. K. & Law, B. K., 2019 Dec 1, In : Cell Death Discovery. 5, 1, 153.

Research output: Contribution to journal › Article

Open Access

TNF-Related Apoptosis-Inducing Ligand Receptors

Disulfides

Necrosis

Apoptosis

Ligands

Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation

Wang, C. H., Hung, P. W., Chiang, C. W., Lombès, M., Chen, C. H., Lee, K. H., Lo, Y. C., Wu, M. H., Chang, W. C. & Lin, D. Y., 2019 Aug, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 8, p. 1282-1297 16 p.

Research output: Contribution to journal › Article

Mineralocorticoid Receptors

Ubiquitin

Catenins

Aldosterone

Transcriptional Activation

1 Citation (Scopus)

Regulation of septin phosphorylation: SEPT12 phosphorylation in sperm septin assembly

Lin, C. H., Shen, Y. R., Wang, H. Y., Chiang, C-W., Wang, C-Y. & Kuo, P-L., 2019 Jan 1, In : Cytoskeleton. 76, 1, p. 137-142 6 p.

Research output: Contribution to journal › Review article

Septins

Spermatozoa

Phosphorylation

Sumoylation

Sperm Motility

5 Citations (Scopus)

CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression

Liao, S. Y., Chiang, C-W., Hsu, C. H., Chen, Y. T., Jen, J., Juan, H. F., Lai, W-W. & Wang, Y-C., 2017 Oct 12, In : Oncogene. 36, 41, p. 5722-5733 12 p.

Research output: Contribution to journal › Article

Oncogene Proteins

Zinc Fingers

Lung Neoplasms

Serine

Phosphorylation