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Research Output 2004 2019

  • 822 Citations
  • 16 h-Index
  • 43 Article
  • 5 Patent
  • 3 Conference contribution
  • 2 Review article
2019
5 Citations (Scopus)
Fibroblast Growth Factor 9
Corpus Striatum
Huntington Disease
Oxidative stress
Oxidative Stress

Regeneration of rete ridges in Lanyu pig (Sus scrofa): Insights for human skin wound healing

Lin, C. H., Chiu, P. Y., Hsueh, Y-Y., Shieh, S-J., Wu, C-C., Wong, T-W., Chuong, C. M. & Hughes, M. W., 2019 Apr 1, In : Experimental Dermatology. 28, 4, p. 472-479 8 p.

Research output: Contribution to journalArticle

Sus scrofa
Proliferating Cell Nuclear Antigen
Wound Healing
Alkaline Phosphatase
Regeneration
2018
6 Citations (Scopus)

Bioadhesive Polymersome for Localized and Sustained Drug Delivery at Pathological Sites with Harsh Enzymatic and Fluidic Environment via Supramolecular Host–Guest Complexation

Zhu, M., Wei, K., Lin, S., Chen, X., Wu, C-C., Li, G. & Bian, L., 2018 Feb 15, In : Small. 14, 7, 1702288.

Research output: Contribution to journalArticle

Polycaprolactone
Cyclodextrins
Fluidics
Complexation
Drug delivery
8 Citations (Scopus)

FGF9/FGFR2 increase cell proliferation by activating ERK1/2, Rb/E2F1, and cell cycle pathways in mouse Leydig tumor cells

Chang, M. M., Lai, M. S., Hong, S. Y., Pan, B. S., Huang, H., Yang, S. H., Wu, C. C., Sun, H. S., Chuang, J. I., Wang, C. Y. & Huang, B. M., 2018 Nov 1, In : Cancer Science. 109, 11, p. 3503-3518 16 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 9
Leydig Cell Tumor
Fibroblast Growth Factor Receptors
Retinoblastoma
Fibroblast Growth Factor 2
3 Citations (Scopus)

Fibroblast Growth Factor 9 Suppresses Striatal Cell Death Dominantly Through ERK Signaling in Huntington's Disease

Yusuf, I. O., Cheng, P. H., Chen, H. M., Chang, Y. F., Chang, C. Y., Yang, H. I., Lin, C. W., Tsai, S. J., Chuang, J. I., Wu, C. C., Huang, B. M., Sun, H. S. & Yang, S. H., 2018 Aug 1, In : Cellular Physiology and Biochemistry. 48, 2, p. 605-617 13 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 9
Corpus Striatum
Huntington Disease
Cell Death
MAP Kinase Signaling System
3 Citations (Scopus)

Hypoxia-Preconditioned Human Umbilical Vein Endothelial Cells Protect Against Neurovascular Damage After Hypoxic Ischemia in Neonatal Brain

Lee, Y. C., Chang, Y. C., Wu, C-C. & Huang, C-C., 2018 Oct 1, In : Molecular Neurobiology. 55, 10, p. 7743-7757 15 p.

Research output: Contribution to journalArticle

Human Umbilical Vein Endothelial Cells
Ischemia
Brain
Hypoxia
Genes
2017
6 Citations (Scopus)

Endothelial differentiation of bone marrow mesenchyme stem cells applicable to hypoxia and increased migration through Akt and NFκB signals

Liu, C., Tsai, A. L., Li, P. C., Huang, C. W. & Wu, C-C., 2017 Feb 7, In : Stem Cell Research and Therapy. 8, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Endothelial cells
Mesoderm
Stem cells
Mesenchymal Stromal Cells
Bone
2 Citations (Scopus)

Interaction of Zap70 and CXCR4 receptor at lamellipodia that determines the directionality during Jurkat T cells chemotaxis

Wu, C. Y., Tsai, Y. Y., Chen, S. Y., Lin, Y. P., Shin, J-W., Wu, C-C. & Yang, B-C., 2017 Oct 1, In : Molecular Immunology. 90, p. 245-254 10 p.

Research output: Contribution to journalArticle

CXCR4 Receptors
Pseudopodia
Jurkat Cells
Chemotaxis
T-Lymphocytes
18 Citations (Scopus)

Mussel-mimetic hydrogels with defined cross-linkers achieved: Via controlled catechol dimerization exhibiting tough adhesion for wet biological tissues

Zhao, P., Wei, K., Feng, Q., Chen, H., Wong, D. S. H., Chen, X., Wu, C-C. & Bian, L., 2017 Jan 1, In : Chemical Communications. 53, 88, p. 12000-12003 4 p.

Research output: Contribution to journalArticle

Hydrogels
Dimerization
Adhesion
Tissue
Nucleophiles
2016
12 Citations (Scopus)

Assembling Composite Dermal Papilla Spheres with Adipose-derived Stem Cells to Enhance Hair Follicle Induction

Huang, C. F., Chang, Y. J., Hsueh, Y-Y., Huang, C. W., Wang, D. H., Huang, T. C., Wu, Y. T., Su, F., Hughes, M. W., Chuong, C. M. & Wu, C-C., 2016 May 23, In : Scientific reports. 6, 26436.

Research output: Contribution to journalArticle

Hair Follicle
Stem Cells
Skin
Hair
Peroxisome Proliferator-Activated Receptors

Cross-Sectional Nakagami Images in Passive Stretches Reveal Damage of Injured Muscles

Lin, S. P., Lin, Y. H., Fan, S. C., Huang, B-M., Lin, W. Y., Wang, S-H., Shung, K. K., Su, F. & Wu, C-C., 2016 Jan 1, In : BioMed research international. 2016, 6893712.

Research output: Contribution to journalArticle

Muscle
Muscles
Muscle Stretching Exercises
Ultrasonics
Ultrasonography
9 Citations (Scopus)

Cyclic stretch facilitates myogenesis in C2C12 myoblasts and rescues Thiazolidinedione-Inhibited Myotube Formation

Chang, Y. J., Chen, Y. J., Huang, C. W., Fan, S. C., Huang, B-M., Chang, W-T., Tsai, Y-S., Su, F. & Wu, C-C., 2016 Mar 21, In : Frontiers in Bioengineering and Biotechnology. 4, MAR, 27.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Muscle Development
Myoblasts
Skeletal Muscle Fibers
Response Elements
10 Citations (Scopus)

Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse leydig tumor cells

So, E. C., Chen, Y. C., Wang, S. C., Wu, C-C., Huang, M. C., Lai, M. S., Pan, B. S., Kang, F. C. & Huang, B-M., 2016 Apr 27, In : OncoTargets and Therapy. 9, p. 2519-2533 15 p.

Research output: Contribution to journalArticle

Leydig Cell Tumor
Endoplasmic Reticulum Stress
Midazolam
Autophagy
Caspases
4 Citations (Scopus)

Novel skin chamber for rat ischemic flap studies in regenerative wound repair

Hsueh, Y-Y., Wang, D. H., Huang, T. C., Chang, Y. J., Shao, W. C., Tuan, T. L., Hughes, M. W. & Wu, C-C., 2016 May 17, In : Stem Cell Research and Therapy. 7, 1, 72.

Research output: Contribution to journalArticle

Rats
Skin
Repair
Wounds and Injuries
Necrosis
5 Citations (Scopus)

Role of Excessive Autophagy Induced by Mechanical Overload in Vein Graft Neointima Formation: Prediction and Prevention

Chang, Y. J., Huang, H. C., Hsueh, Y. Y., Wang, S. W., Su, F. C., Chang, C. H., Tang, M. J., Li, Y. S., Wang, S. H., Shung, K. K., Chien, S. & Wu, C. C., 2016 Feb 26, In : Scientific reports. 6, 22147.

Research output: Contribution to journalArticle

Neointima
Autophagy
Veins
Transplants
Ultrasonics
3 Citations (Scopus)

The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes

Lai, M. S., Wang, C-Y., Yang, S-H., Wu, C-C., Sun, H-F., Tsai, S-J., Chuang, J-I., Chen, Y. C. & Huang, B-M., 2016 Apr 2, In : Organogenesis. 12, 2, p. 61-77 17 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 9
Fibroblasts
Testis
Spermatids
Leydig Cells
2015
1 Citation (Scopus)

Diagnostic value of methylated human telomerase reverse transcriptase in human cancers: A meta-analysis

Gao, W., Shi, Y., Liu, W., Lin, W. Y., Wu, J. C. C., Chan, J. Y. W. & Wong, T. S., 2015 Jan 1, In : Frontiers in Oncology. 5, DEC, 296.

Research output: Contribution to journalArticle

Meta-Analysis
Neoplasms
Methylation
human TERT protein
CpG Islands
4 Citations (Scopus)
Neuropilin-1
Vascular Endothelial Growth Factor Receptor-2
Endothelial cells
Shear stress
Brain
13 Citations (Scopus)

Synergy of endothelial and neural progenitor cells from adipose-derived stem cells to preserve neurovascular structures in rat hypoxic-ischemic brain injury

Hsueh, Y-Y., Chang, Y. J., Huang, C. W., Handayani, F., Chiang, Y. L., Fan, S. C., Ho, C. J., Kuo, Y-M., Yang, S-H., Chen, Y-L., Lin, S. C., Huang, C-C. & Wu, C-C., 2015 Oct 8, In : Scientific reports. 5, 14985.

Research output: Contribution to journalArticle

Brain Injuries
Stem Cells
Neuropilin-1
Receptor, Fibroblast Growth Factor, Type 1
CXC Chemokines
2014
47 Citations (Scopus)

Functional recoveries of sciatic nerve regeneration by combining chitosan-coated conduit and neurosphere cells induced from adipose-derived stem cells

Hsueh, Y-Y., Chang, Y. J., Huang, T. C., Fan, S. C., Wang, D. H., Chen, J-J., Wu, C-C. & Lin, S. C., 2014 Feb 1, In : Biomaterials. 35, 7, p. 2234-2244 11 p.

Research output: Contribution to journalArticle

Nerve Regeneration
Chitosan
Sciatic Nerve
Stem cells
Stem Cells
6 Citations (Scopus)
Osteoblasts
Ultrasonics
Phosphatases
Bone
Cells
9 Citations (Scopus)

Monitoring tissue inflammation and responses to drug treatments in early stages of mice bone fracture using 50 MHz ultrasound

Chen, Y. C., Lin, Y. H., Wang, S. H., Lin, S. P., Shung, K. K. & Wu, C. C., 2014 Jan 1, In : Ultrasonics. 54, 1, p. 177-186 10 p.

Research output: Contribution to journalArticle

bones
mice
drugs
death
staining
14 Citations (Scopus)

Radiation sensitization of tumor cells induced by shear stress: The roles of integrins and FAK

Luo, C. W., Wu, C-C. & Ch'ang, H. J., 2014 Jan 1, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 9, p. 2129-2137 9 p.

Research output: Contribution to journalArticle

Integrins
Radiation
Colonic Neoplasms
Neoplasms
Extracellular Fluid
2013
25 Citations (Scopus)

Enhancement of renal epithelial cell functions through microfluidic-based coculture with adipose-derived stem cells

Huang, H. C., Chang, Y. J., Chen, W. C., Harn, H. I. C., Tang, M. J. & Wu, C. C., 2013 Sep 1, In : Tissue Engineering - Part A. 19, 17-18, p. 2024-2034 11 p.

Research output: Contribution to journalArticle

Microfluidics
Coculture Techniques
Stem cells
Stem Cells
Collagen
16 Citations (Scopus)

Human umbilical vein endothelial cells protect against hypoxic-ischemic damage in neonatal brain via stromal cell-derived factor 1/C-X-C chemokine receptor type 4

Wu, C-C., Chen, Y. C., Chang, Y. C., Wang, L. W., Lin, Y-C., Chiang, Y. L., Ho, C. J. & Huang, C-C., 2013 May 1, In : Stroke. 44, 5, p. 1402-1409 8 p.

Research output: Contribution to journalArticle

Chemokine CXCL12
CXC Chemokines
Chemokine Receptors
Human Umbilical Vein Endothelial Cells
Brain
8 Citations (Scopus)

The role of RhoA kinase inhibition in human placenta-derived multipotent cells on neural phenotype and cell survival

Wang, C. H., Wu, C-C., Hsu, S. H., Liou, J. Y., Li, Y. W., Wu, K. K., Lai, Y. K. & Yen, B. L., 2013 Apr 1, In : Biomaterials. 34, 13, p. 3223-3230 8 p.

Research output: Contribution to journalArticle

Stem cells
Placenta
Cell Survival
Phosphotransferases
Cells
2012
12 Citations (Scopus)

Facilitation of human osteoblast apoptosis by sulindac and indomethacin under hypoxic injury

Liu, C., Tsai, A. L., Chen, Y. C., Fan, S. C., Huang, C. H., Wu, C. C. & Chang, C. H., 2012 Jan 1, In : Journal of Cellular Biochemistry. 113, 1, p. 148-155 8 p.

Research output: Contribution to journalArticle

Sulindac
Osteoblasts
Indomethacin
Apoptosis
Anti-Inflammatory Agents
4 Citations (Scopus)

Inhibitory effect of botulinum toxin type A on the NANC system in rat respiratory models of neurogenic inflammation

Chien, C. T., Lee, H. M., Wu, C-C. & Li, P. C., 2012 Aug 15, In : Archives of Biochemistry and Biophysics. 524, 2, p. 106-113 8 p.

Research output: Contribution to journalArticle

Neurogenic Inflammation
Type A Botulinum Toxins
Rats
Cerebral Arteries
Synaptosomal-Associated Protein 25
10 Citations (Scopus)
Mechanical properties
Foam Cells
Cellular Structures
Cytoskeleton
Joints
16 Citations (Scopus)

Mediation of the migration of endothelial cells and fibroblasts on polyurethane nanocomposites by the activation of integrin-focal adhesion kinase signaling

Hung, H. S., Chu, M. Y., Lin, C. H., Wu, C-C. & Hsu, S. H., 2012 Jan 1, In : Journal of Biomedical Materials Research - Part A. 100 A, 1, p. 26-37 12 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Polyurethanes
Endothelial cells
Fibroblasts
Integrins
13 Citations (Scopus)

PTEN overexpression attenuates angiogenic processes of endothelial cells by blockade of endothelin-1/endothelin B receptor signaling

Kuo, H. M., Lin, C. Y., Lam, H. C., Lin, P. R., Chan, H. H., Tseng, J. C., Sun, C. K., Hsu, T. F., Wu, C-C., Yang, C. Y., Hsu, C. M. & Tai, M. H., 2012 Apr 1, In : Atherosclerosis. 221, 2, p. 341-349 9 p.

Research output: Contribution to journalArticle

Endothelin B Receptors
Endothelin-1
Endothelial Cells
Transplants
Thrombosis
16 Citations (Scopus)

Spheroid formation and neural induction in human adipose-derived stem cells on a chitosan-coated surface

Hsueh, Y-Y., Chiang, Y. L., Wu, C-C. & Lin, S. C., 2012 Jun 1, In : Cells Tissues Organs. 196, 2, p. 117-128 12 p.

Research output: Contribution to journalArticle

Chitosan
Stem Cells
Nerve Regeneration
Multipotent Stem Cells
Nestin
4 Citations (Scopus)

The inhibition effect of low-intensity pulsed ultrasound on osteoclasts progenitor cells

Chen, S. H., Wu, C-C., Wang, S-H. & Li, W. T., 2012 Dec 1, 2012 IEEE International Ultrasonics Symposium, IUS 2012. p. 607-610 4 p. 6562529. (IEEE International Ultrasonics Symposium, IUS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

cells
phosphatases
bones
polymerase chain reaction
osteoblasts

The optimal vibrational shear stress for bovine endothelial cell proliferation

Li, C. W., Chen, J. L., Wu, C-C. & Wang, G. J., 2012 Jun 1, 2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012. p. 716-720 5 p. 6196875. (2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Endothelial cells
Cell proliferation
Shear stress
Lead
Scaffolds
2011
46 Citations (Scopus)

DDR1 triggers epithelial cell differentiation by promoting cell adhesion through stabilization of E-cadherin

Yeh, Y. C., Wu, C-C., Wang, Y-G. & Tang, M-J., 2011 Apr 1, In : Molecular Biology of the Cell. 22, 7, p. 940-953 14 p.

Research output: Contribution to journalArticle

Cadherins
Cell Adhesion
Cell Differentiation
Epithelial Cells
Discoidin Domain Receptor 1
23 Citations (Scopus)

Review: Roles of microenvironment and mechanical forces in cell and tissue remodeling

Su, F., Wu, C-C. & Chien, S., 2011 Oct 3, In : Journal of Medical and Biological Engineering. 31, 4, p. 233-244 12 p.

Research output: Contribution to journalReview article

Tissue
Biomedical Engineering
Cellular Microenvironment
Signal transduction
Biochemistry
2010
9 Citations (Scopus)
Focal Adhesions
cytoskeleton
Cytoskeleton
adhesion
Struts
2009

Involvement of focal adhesion kinase in cell adhesion force on different substrate rigidity

Su, F. C., Shao, F. Y., Wu, C. C., Yeh, M. L. & Tang, M. J., 2009 Sep 21, NEBEC 2009 - Proceedings of the IEEE 35th Annual Northeast Bioengineering Conference. 4967781. (Bioengineering, Proceedings of the Northeast Conference).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Focal Adhesion Protein-Tyrosine Kinases
Cell adhesion
Rigidity
Adhesion
Substrates
26 Citations (Scopus)

Shear Stress Inhibits Homocysteine-Induced Stromal Cell-Derived Factor-1 Expression in Endothelial Cells

Sung, M. L., Wu, C. C., Chang, H. I., Yen, C. K., Chen, H. J., Cheng, J. C., Chien, S. & Chen, C. N., 2009 Oct 1, In : Circulation Research. 105, 8, p. 755-763 9 p.

Research output: Contribution to journalArticle

Chemokine CXCL12
Homocysteine
Endothelial Cells
JNK Mitogen-Activated Protein Kinases
Transcription Factor AP-1
52 Citations (Scopus)

The behavior of endothelial cells on polyurethane nanocomposites and the associated signaling pathways

Hung, H. S., Wu, C-C., Chien, S. & Hsu, S. H., 2009 Mar 1, In : Biomaterials. 30, 8, p. 1502-1511 10 p.

Research output: Contribution to journalArticle

Nanocomposites
Polyurethanes
Endothelial cells
Endothelial Cells
Focal Adhesion Protein-Tyrosine Kinases
2008
33 Citations (Scopus)

Nonsteroidal anti-inflammatory drugs induced endothelial apoptosis by perturbing peroxisome proliferator-activated receptor-δ transcriptional pathway

Liou, J. Y., Wu, C. C., Chen, B. R., Yen, L. B. & Wu, K. K., 2008 Nov 1, In : Molecular Pharmacology. 74, 5, p. 1399-1406 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Anti-Inflammatory Agents
Apoptosis
Sulfides
Pharmaceutical Preparations
74 Citations (Scopus)

Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells

Wu, C-C., Chao, Y. C., Chen, C. N., Chien, S., Chen, Y. C., Chien, C. C., Chiu, J. J. & Linju Yen, B., 2008 Jan 10, In : Journal of Biomechanics. 41, 4, p. 813-821 9 p.

Research output: Contribution to journalArticle

Endothelial cells
Placenta
Shear stress
Endothelial Cells
Endothelial Growth Factors
2007
66 Citations (Scopus)

Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry

Wu, C. C., Li, Y. S., Haga, J. H., Kaunas, R., Chiu, J. J., Su, F. C., Usami, S. & Chien, S., 2007 Jan 23, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 4, p. 1254-1259 6 p.

Research output: Contribution to journalArticle

Endothelial Cells
Apoptosis
Stress Fibers
Focal Adhesion Protein-Tyrosine Kinases
Human Umbilical Vein Endothelial Cells
2006
42 Citations (Scopus)

Roles of MAP kinases in the regulation of bone matrix gene expressions in human osteoblasts by oscillatory fluid flow

Wu, C-C., Li, Y. S., Haga, J. H., Wang, N., Lian, I. Y. Z., Su, F., Usami, S. & Chien, S., 2006 Jun 1, In : Journal of Cellular Biochemistry. 98, 3, p. 632-641 10 p.

Research output: Contribution to journalArticle

Bone Matrix
Osteoblasts
Gene expression
Flow of fluids
Bone
92 Citations (Scopus)

Shear stress regulation of Krüppel-like factor 2 expression is flow pattern-specific

Wang, N., Miao, H., Li, Y. S., Zhang, P., Haga, J. H., Hu, Y., Young, A., Yuan, S., Nguyen, P., Wu, C-C. & Chien, S., 2006 Mar 24, In : Biochemical and Biophysical Research Communications. 341, 4, p. 1244-1251 8 p.

Research output: Contribution to journalArticle

Endothelial cells
Flow patterns
Shear stress
Endothelial Cells
Blood Vessels
2005
31 Citations (Scopus)
Focal Adhesion Protein-Tyrosine Kinases
Adhesion
Hepatocyte Growth Factor
Optical Tweezers
Madin Darby Canine Kidney Cells
2004
3 Citations (Scopus)

Kinematics of lower extremity in tennis flat and spin serve

Lo, K. C., Wang, L. H., Wu, C. C. & Su, F. C., 2004 Dec 1, In : Journal of Medical and Biological Engineering. 24, 4, p. 209-212 4 p.

Research output: Contribution to journalArticle

Kinematics
Biomechanics
Sports
Teaching
Motion analysis
13 Citations (Scopus)

The Technique for Measurement of Cell Adhesion Force

Lee, C. C., Wu, C. C. & Su, F. C., 2004 Mar 1, In : Journal of Medical and Biological Engineering. 24, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

Cell adhesion
Fibroblasts
Microscopes
Adhesion
Optical tweezers
1800

Biaxial tissue-stretched device

Su, F. & Wu, C-C., 1800, Patent No. I424059

Research output: Patent