• 2476 Citations
  • 28 h-Index
20042019
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Research Output 2004 2019

2019
3 Citations (Scopus)

A nationwide survey of adherence to analgesic drugs among cancer patients in Taiwan: prevalence, determinants, and impact on quality of life

Chou, W. C., Chen, J. S., Hung, C. Y., Lu, C. H., Shao, Y. Y., Chiou, T. J., Sung, Y. C., Rau, K. M., Yen, C-J., Yeh, S. P., Liu, T. C., Wu, M. F., Lee, M. Y., Yu, M. S., Hwang, W. L., Lai, P. Y., Chang, C. S. & Hsieh, R. K., 2019 Aug 1, In : Supportive Care in Cancer. 27, 8, p. 2857-2867 11 p.

Research output: Contribution to journalArticle

Taiwan
Analgesics
Quality of Life
Neoplasms
Pain

Differential Organ-Specific Tumor Response to Immune Checkpoint Inhibitors in Hepatocellular Carcinoma

Lu, L. C., Hsu, C., Shao, Y. Y., Chao, Y., Yen, C-J., Shih, I. L., Hung, Y. P., Chang, C. J., Shen, Y. C., Guo, J. C., Liu, T. H., Hsu, C. H. & Cheng, A. L., 2019 Jan 1, (Accepted/In press) In : Liver Cancer.

Research output: Contribution to journalArticle

Open Access
Hepatocellular Carcinoma
Liver
Neoplasms
Lung
Monoclonal Antibodies

Effect of First-line S-1 Plus Oxaliplatin With or Without Ramucirumab Followed by Paclitaxel Plus Ramucirumab on Advanced Gastric Cancer in East Asia: The Phase 2 RAINSTORM Randomized Clinical Trial

Yoshikawa, T., Muro, K., Shitara, K., Oh, D. Y., Kang, Y. K., Chung, H. C., Kudo, T., Chin, K., Kadowaki, S., Hamamoto, Y., Hironaka, S., Yoshida, K., Yen, C-J., Omuro, Y., Bai, L. Y., Maeda, K., Ozeki, A., Yoshikawa, R. & Kitagawa, Y., 2019 Aug 2, In : JAMA network open. 2, 8, p. e198243

Research output: Contribution to journalArticle

Open Access
oxaliplatin
Far East
Paclitaxel
Stomach Neoplasms
Randomized Controlled Trials

Generation of a heterozygous p53 R249S mutant human embryonic stem cell line by TALEN-mediated genome editing

Huo, Z., Tu, J., Xu, A., Li, Y., Wang, D., Liu, M., Zhou, R., Zhu, D., Lin, Y., Gingold, J. A., Yen, C-J., Xiao, H. & Zhao, R., 2019 Jan 1, In : Stem Cell Research. 34, 101360.

Research output: Contribution to journalArticle

Open Access
Cell Line
Mutation
Germ Layers
Teratoma
Liver Neoplasms

Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis

Yen, C-J., Yang, S. T., Chen, R. Y., Huang, W-Y., Chayama, K., Lee, M. H., Yang, S. J., Lai, H. S., Yen, H. Y., Hsiao, Y. W., Wang, J-M., Lin, Y-J. & Hung, L-Y., 2019 Jun 6, In : Journal of biomedical science. 26, 1, 44.

Research output: Contribution to journalArticle

Open Access
Proteins
Hepatocellular Carcinoma
Viruses
Hepatitis B virus
Cyclic AMP Response Element-Binding Protein
1 Citation (Scopus)

Maintenance avelumab versus continuation of first-line chemotherapy in gastric cancer: JAVELIN Gastric 100 study design

Moehler, M., Ryu, M. H., Dvorkin, M., Lee, K. W., Coşkun, H., Wong, R., Chung, H. C., Poltoratsky, A., Tsuji, A., Yen, C-J., Muntean, A. S., Le Sourd, S., Vaccaro, G. M., Overton, L., Boku, N., Wainberg, Z. A., Patel, M., Sharma, M., Xiong, H., Conti, I. & 2 others, Taieb, J. & Bang, Y. J., 2019 Feb 1, In : Future Oncology. 15, 6, p. 567-577 11 p.

Research output: Contribution to journalArticle

Open Access
Stomach Neoplasms
Esophagogastric Junction
Stomach
oxaliplatin
Maintenance

Multimodal exercise ameliorates exercise responses and body composition in head and neck cancer patients receiving chemotherapy

Yen, C-J., Hung, C-H., Kao, C. L., Tsai, W. M., Chan, S-H., Cheng, H. C., Jheng, W. T., Lu, Y. J. & Tsai, K-L., 2019 Jan 1, In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Body Composition
Exercise
Drug Therapy
Heart Rate

Oral hygiene and the overall survival of head and neck cancer patients

Chang, C-C., Lee, W-T., Hsiao, J-R., Ou, C-Y., Huang, C-C., Tsai, S-T., Chen, K-C., Huang, J-S., Wang, D-Y., Lai, Y-H., Wu, Y-H., Hsueh, W-T., Wu, S-Y., Yen, C-J., Chang, J-Y., Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2019 Apr 1, In : Cancer medicine. 8, 4, p. 1854-1864 11 p.

Research output: Contribution to journalArticle

Open Access
Oral Hygiene
Head and Neck Neoplasms
Survival
Confidence Intervals
Tooth

Patients with head and neck cancer may need more intensive pain management to maintain daily functioning: a multi-center study

Cho, S. F., Rau, K. M., Shao, Y. Y., Yen, C-J., Wu, M. F., Chen, J. S., Chang, C. S., Yeh, S. P., Chiou, T. J., Hsieh, R. K., Lee, M. Y., Sung, Y. C., Lee, K. D., Lai, P. Y., Yu, M. S., Hwang, W. L. & Liu, T. C., 2019 May 1, In : Supportive Care in Cancer. 27, 5, p. 1663-1672 10 p.

Research output: Contribution to journalArticle

Pain Management
Head and Neck Neoplasms
Pain
Walking
Analgesics
33 Citations (Scopus)
Fetal Proteins
Hepatocellular Carcinoma
Placebos
sorafenib
ramucirumab
1 Citation (Scopus)
Neoadjuvant Therapy
Squamous Cell Carcinoma
Clinical Trials
Staining and Labeling
Neoplasms
Head and Neck Neoplasms
Alcohol Drinking
Ethanol
Survival
Genes
Head and Neck Neoplasms
Alcohols
Surveys and Questionnaires
Alleles
Validation Studies
2018
5 Citations (Scopus)

Alpha-fetoprotein kinetics in patients with hepatocellular carcinoma receiving ramucirumab or placebo: An analysis of the phase 3 REACH study

Chau, I., Park, J. O., Ryoo, B. Y., Yen, C-J., Poon, R., Pastorelli, D., Blanc, J. F., Kudo, M., Pfiffer, T., Hatano, E., Chung, H. C., Kopeckova, K., Phelip, J. M., Brandi, G., Ohkawa, S., Li, C. P., Okusaka, T., Hsu, Y., Abada, P. B. & Zhu, A. X., 2018 Jul 3, In : British Journal of Cancer. 119, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

alpha-Fetoproteins
Hepatocellular Carcinoma
Placebos
Survival
Therapeutics
4 Citations (Scopus)

A Phase I/Randomized Phase II Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Nintedanib versus Sorafenib in Asian Patients with Advanced Hepatocellular Carcinoma

Yen, C-J., Kim, T. Y., Feng, Y. H., Chao, Y., Lin, D. Y., Ryoo, B. Y., Huang, D. C. L., Schnell, D., Hocke, J., Loembé, A. B. & Cheng, A. L., 2018 May 1, In : Liver Cancer. 7, 2, p. 165-178 14 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Pharmacokinetics
Safety
Maximum Tolerated Dose
Aspartate Aminotransferases
1 Citation (Scopus)

Corrigendum to ‘Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib: Patient-focused outcome results from the randomised phase III REACH study’ [Eur J Canc 81 (2017) 17–25] (S0959804917309334) (10.1016/j.ejca.2017.05.001))

Chau, I., Peck-Radosavljevic, M., Borg, C., Malfertheiner, P., Seitz, J. F., Park, J. O., Ryoo, B. Y., Yen, C-J., Kudo, M., Poon, R., Pastorelli, D., Blanc, J. F., Chung, H. C., Baron, A. D., Okusaka, T., Bowman, L., Cui, Z. L., Girvan, A. C., Abada, P. B., Yang, L. & 1 others, Zhu, A. X., 2018 Sep 1, In : European Journal of Cancer. 100, p. 135-136 2 p.

Research output: Contribution to journalComment/debate

Hepatocellular Carcinoma
Stomach
Emotions
Pain
Therapeutics
2 Citations (Scopus)

Exposure–response relationship of ramucirumab in East Asian patients from RAINBOW: a randomized clinical trial in second-line treatment of gastric cancer

Kim, T. Y., Yen, C-J., Al-Batran, S. E., Ferry, D., Gao, L., Hsu, Y., Cheng, R., Orlando, M. & Ohtsu, A., 2018 Mar 1, In : Gastric Cancer. 21, 2, p. 276-284 9 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Randomized Controlled Trials
Therapeutics
Esophagogastric Junction
Paclitaxel

Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C., Ai, Y., Tsai, H., Chan, S., Yen, C., Cheng, K., Lee, Y., Kao, C., Wang, Y., Chen, Y., Lin, C., Liu, T., Tsai, H., Wang, J., Su, I. & Huang, W., 2018 Sep 1, In : Hepatology. 68, 3, p. 815-826

Research output: Contribution to journalArticle

5 Citations (Scopus)

Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C-J., Ai, Y. L., Tsai, H-W., Chan, S-H., Yen, C. S., Cheng, K. H., Lee, Y. P., Kao, C. W., Wang, Y. C., Chen, Y. L., Lin, C. H., Liu, T., Tsai, H. P., Wang, J-R., Su, I. J. & Huang, W-Y., 2018 Sep 1, In : Hepatology. 68, 3, p. 815-826 12 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Biomarkers
Recurrence
Surface Antigens
9 Citations (Scopus)

Hepatocellular carcinoma–related cyclin D1 is selectively regulated by autophagy degradation system

Wu, S. Y., Lan, S. H., Wu, S-R., Chiu, Y. C., Lin, X-Z., Su, I. J., Tsai, T. F., Yen, C-J., Lu, T-H., Liang, F. W., Li, C-Y., Su, H-J., Su, C. L. & Liu, H-S., 2018 Jul 1, In : Hepatology. 68, 1, p. 141-154 14 p.

Research output: Contribution to journalArticle

Cyclin D1
Autophagy
Hepatocellular Carcinoma
Neoplasms
Carcinogenesis
1 Citation (Scopus)

NEK2 promotes hepatoma metastasis and serves as biomarker for high recurrence risk after hepatic resection

Chang, Y. Y., Yen, C-J., Chan, S-H., Chou, Y. W., Lee, Y. P., Bao, C. Y., Huang, C. J. & Huang, W-Y., 2018 Sep 1, In : Annals of Hepatology. 17, 5, p. 843-856 14 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Biomarkers
Neoplasm Metastasis
Recurrence
Liver

NEK2 Promotes Hepatoma Metastasis and Serves as Biomarker for High Recurrence Risk after Hepatic Resection

Chang, Y., Yen, C., Chan, S., Chou, Y., Lee, Y., Bao, C., Huang, C. & Huang, W., 2018 Aug 24, In : Annals of Hepatology. 17, 5, p. 843-856

Research output: Contribution to journalArticle

85 Citations (Scopus)

Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial

KEYNOTE-061 investigators, 2018 Jul 14, In : The Lancet. 392, 10142, p. 123-133 11 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Paclitaxel
Stomach
Cell Death
Survival
22 Citations (Scopus)

Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma

Abou-Alfa, G. K., Qin, S., Ryoo, B. Y., Lu, S. N., Yen, C-J., Feng, Y. H., Lim, H. Y., Izzo, F., Colombo, M., Sarker, D., Bolondi, L., Vaccaro, G., Harris, W. P., Chen, Z., Hubner, R. A., Meyer, T., Sun, W., Harding, J. J., Hollywood, E. M., Ma, J. & 7 others, Wan, P. J., Ly, M., Bomalaski, J., Johnston, A., Lin, C. C., Chao, Y. & Chen, L. T., 2018 Jun 1, In : Annals of Oncology. 29, 6, p. 1402-1408 7 p.

Research output: Contribution to journalArticle

Arginine
Hepatocellular Carcinoma
Patient Care
Placebos
Survival
2 Citations (Scopus)

Phase II studies with refametinib or refametinib plus sorafenib in patients with RAS-mutated hepatocellular Carcinoma

Lim, H. Y., Merle, P., Weiss, K. H., Yau, T., Ross, P., Mazzaferro, V., Blanc, J. F., Ma, Y. T., Yen, C-J., Kocsis, J., Choo, S. P., Sukeepaisarnjaroen, W., Gerolami, R., Dufour, J. F., Gane, E. J., Ryoo, B. Y., Peck-Radosavljevic, M., Dao, T., Yeo, W., Lamlertthon, W. & 7 others, Thongsawat, S., Teufel, M., Roth, K., Reis, D., Childs, B. H., Krissel, H. & Llovet, J. M., 2018 Oct 1, In : Clinical Cancer Research. 24, 19, p. 4650-4661 12 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Mutation
DNA
Magnetics
Disease-Free Survival
1 Citation (Scopus)

Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma

Tsai, H-W., Ho, C-L., Cheng, S. W., Lin, Y-J., Chen, C. C., Cheng, P-N., Yen, C-J., Chang, T-T., Chiang, P-M., Chan, S-H., Ho, C. H., Chen, S-H., Wang, Y. W., Chow, N-H. & Lin, J. C., 2018 Mar 14, In : World journal of gastroenterology. 24, 10, p. 1152-1166 15 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Hepatocellular Carcinoma
Biomarkers
Membranes
Atlases
2 Citations (Scopus)

Ramucirumab safety in East Asian patients: A meta-analysis of six global, randomized, double-blind, placebo-controlled, phase III clinical trials

Yen, C-J., Muro, K., Kim, T. W., Kudo, M., Shih, J. Y., Lee, K. W., Chao, Y., Kim, S. W., Yamazaki, K., Sohn, J. H., Cheng, R., Zhang, Y., Binder, P., Mi, G., Orlando, M. & Chung, H. C., 2018 Mar 1, In : Journal of Global Oncology. 2018, 4

Research output: Contribution to journalArticle

Open Access
Phase III Clinical Trials
Meta-Analysis
Placebos
Safety
ramucirumab

Satisfaction with pain management and impact of pain on quality of life in cancer patients

Lin, J., Hsieh, R. K., Chen, J. S., Lee, K. D., Rau, K. M., Shao, Y. Y., Sung, Y. C., Yeh, S. P., Chang, C. S., Liu, T. C., Wu, M. F., Lee, M. Y., Yu, M. S., Yen, C-J., Lai, P. Y., Hwang, W. L. & Chiou, T. J., 2018 Jan 1, (Accepted/In press) In : Asia-Pacific Journal of Clinical Oncology.

Research output: Contribution to journalArticle

Pain Management
Quality of Life
Pain
Neoplasms
Taiwan
4 Citations (Scopus)
Microbiota
Genetic Polymorphisms
Life Style
Squamous Cell Carcinoma
Oral Hygiene
2017
11 Citations (Scopus)

A phase I/II multicenter study of single-agent foretinib as first-line therapy in patients with advanced hepatocellular carcinoma

Yau, T. C. C., Lencioni, R., Sukeepaisarnjaroen, W., Chao, Y., Yen, C-J., Lausoontornsiri, W., Chen, P. J., Sanpajit, T., Camp, A., Cox, D. S., Gagnon, R. C., Liu, Y., Raffensperger, K. E., Kulkarni, D. A., Kallender, H., Ottesen, L. H., Poon, R. T. P. & Bottaro, D. P., 2017 May 15, In : Clinical Cancer Research. 23, 10, p. 2405-2413 9 p.

Research output: Contribution to journalArticle

Multicenter Studies
Hepatocellular Carcinoma
Maximum Tolerated Dose
Interleukin-8
Therapeutics
18 Citations (Scopus)

A randomized, open-label, Phase III clinical trial of nivolumab vs. therapy of investigator's choice in recurrent squamous cell carcinoma of the head and neck: A subanalysis of Asian patients versus the global population in checkmate 141

Kiyota, N., Hasegawa, Y., Takahashi, S., Yokota, T., Yen, C-J., Iwae, S., Shimizu, Y., Hong, R. L., Goto, M., Kang, J. H., Sum Kenneth Li, W., Ferris, R. L., Gillison, M., Namba, Y., Monga, M., Lynch, M. & Tahara, M., 2017 Oct 1, In : Oral Oncology. 73, p. 138-146 9 p.

Research output: Contribution to journalArticle

Phase III Clinical Trials
Research Personnel
Confidence Intervals
Population
Therapeutics
8 Citations (Scopus)

Cell-free methylation markers with diagnostic and prognostic potential in hepatocellular carcinoma

Lu, C. Y., Chen, S. Y., Peng, H. L., Kan, P. Y., Chang, W. C. & Yen, C-J., 2017 Jan 1, In : Oncotarget. 8, 4, p. 6406-6418 13 p.

Research output: Contribution to journalArticle

Methylation
Hepatocellular Carcinoma
MicroRNAs
alpha-Fetoproteins
Sensitivity and Specificity
3 Citations (Scopus)

Hepatocellular carcinoma-associated single-nucleotide variants and deletions identified by the use of genome-wide high-throughput analysis of hepatitis B virus

Liu, W. C., Wu, I-C., Lee, Y. C., Lin, C. P., Cheng, J. H., Lin, Y-J., Yen, C-J., Cheng, P-N., Li, P. F., Cheng, Y. T., Cheng, P. W., Sun, K. T., Yan, S. L., Lin, J. J., Yang, J. C., Chang, K-C., Ho, C. H., Tseng, V. S., Chang, B. C. H., Wu, J. C. & 1 others, Chang, T-T., 2017 Oct 1, In : Journal of Pathology. 243, 2, p. 176-192 17 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Nucleotides
Genome
Meta-Analysis
4 Citations (Scopus)

Impact of Undertreatment of Cancer Pain With Analgesic Drugs on Patient Outcomes: A Nationwide Survey of Outpatient Cancer Patient Care in Taiwan

Shen, W. C., Chen, J. S., Shao, Y. Y., Lee, K. D., Chiou, T. J., Sung, Y. C., Rau, K. M., Yen, C-J., Liao, Y. M., Liu, T. C., Wu, M. F., Lee, M. Y., Yu, M. S., Hwang, W. L., Lai, P. Y., Chang, C. S., Chou, W. C. & Hsieh, R. K., 2017 Jul 1, In : Journal of Pain and Symptom Management. 54, 1, p. 55-65.e1

Research output: Contribution to journalArticle

Taiwan
Analgesics
Patient Care
Outpatients
Pain Management
9 Citations (Scopus)

Inhibition of the EGFR/STAT3/CEBPD Axis reverses cisplatin cross-resistance with paclitaxel in the urothelial carcinoma of the urinary bladder

Wang, W. J., Li, C. F., Chu, Y. Y., Wang, Y. H., Hour, T. C., Yen, C-J., Chang, W. C. & Wang, J-M., 2017 Jan 15, In : Clinical Cancer Research. 23, 2, p. 503-513 11 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Paclitaxel
Cisplatin
Urinary Bladder
NSC 74859
10 Citations (Scopus)

Investigating the Association between Alcohol and Risk of Head and Neck Cancer in Taiwan

Huang, C-C., Hsiao, J-R., Lee, W-T., Lee, Y-C., Ou, C-Y., Chang, C-C., Lu, Y. C., Huang, J-S., Wang, D-Y., Chen, K-C., Tsai, S-T., Fang, S-Y., Wu, J-L., Wu, Y-H., Hsueh, W-T., Yen, C-J., Wu, S-Y., Chang, J-Y., Lin, C. L., Wang, Y. H. & 4 others, Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Dec 1, In : Scientific reports. 7, 1, 9701.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Taiwan
Alcohols
Hypopharyngeal Neoplasms
Oropharyngeal Neoplasms
4 Citations (Scopus)

Investigating the association between diet and risk of head and neck cancer in Taiwan

Chang, C-C., Lee, W-T., Lee, Y-C., Huang, C-C., Ou, C-Y., Lin, Y. H., Huang, J-S., Wang, D-Y., Chen, K-C., Hsiao, J-R., Lu, Y. C., Tsai, S-T., Lai, Y-H., Wu, Y-H., Hsueh, W-T., Yen, C-J., Wu, S-Y., Chang, J-Y., Fang, S-Y., Wu, J-L. & 5 others, Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Jan 1, In : Oncotarget. 8, 58, p. 98865-98875 11 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Taiwan
Vegetables
Diet
Fruit
24 Citations (Scopus)

mRECIST to predict survival in advanced hepatocellular carcinoma: Analysis of two randomised phase II trials comparing nintedanib vs sorafenib

Meyer, T., Palmer, D. H., Cheng, A. L., Hocke, J., Loembé, A. B. & Yen, C-J., 2017 Jul 1, In : Liver International. 37, 7, p. 1047-1055 9 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Survival
Confidence Intervals
nintedanib
sorafenib
7 Citations (Scopus)

Phase Ib study of codrituzumab in combination with sorafenib in patients with non-curable advanced hepatocellular carcinoma (HCC)

Abou-Alfa, G. K., Yen, C-J., Hsu, C. H., O’Donoghue, J., Beylergil, V., Ruan, S., Pandit-Taskar, N., Gansukh, B., Lyashchenko, S. K., Ma, J., Wan, P., Shao, Y. Y., Lin, Z. Z., Frenette, C., O’Neil, B., Schwartz, L., Smith-Jones, P. M., Ohtomo, T., Tanaka, T., Morikawa, H. & 10 others, Maki, Y., Ohishi, N., Chen, Y. C., Agajanov, T., Boisserie, F., Di Laurenzio, L., Lee, R., Larson, S. M., Cheng, A. L. & Carrasquilo, J. A., 2017 Feb 1, In : Cancer Chemotherapy and Pharmacology. 79, 2, p. 421-429 9 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Glypicans
Tumors
Hyponatremia
Antibodies, Monoclonal, Humanized
20 Citations (Scopus)

Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma analysis of REACH trial results by child-pugh score

Zhu, A. X., Baron, A. D., Malfertheiner, P., Kudo, M., Kawazoe, S., Pezet, D., Weissinger, F., Brandi, G., Barone, C. A., Okusaka, T., Wada, Y., Park, J. O., Ryoo, B. Y., Cho, J. Y., Chung, H. C., Li, C. P., Yen, C-J., Lee, K. D., Chang, S. C., Yang, L. & 2 others, Abada, P. B. & Chau, I., 2017 Feb 1, In : JAMA Oncology. 3, 2, p. 235-243 9 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Fetal Proteins
Therapeutics
Liver Neoplasms
Survival
18 Citations (Scopus)

Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib: Patient-focused outcome results from the randomised phase III REACH study

Chau, I., Peck-Radosavljevic, M., Borg, C., Malfertheiner, P., Seitz, J. F., Park, J. O., Ryoo, B. Y., Yen, C-J., Kudo, M., Poon, R., Pastorelli, D., Blanc, J. F., Chung, H. C., Baron, A. D., Okusaka, T., Bowman, L., Cui, Z. L., Girvan, A. C., Abada, P. B., Yang, L. & 1 others, Zhu, A. X., 2017 Aug 1, In : European Journal of Cancer. 81, p. 17-25 9 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Placebos
alpha-Fetoproteins
Quality of Life
Therapeutics

Regular recreational physical activity and risk of head and neck cancer

Lin, C. L., Lee, W-T., Ou, C-Y., Hsiao, J-R., Huang, C-C., Huang, J-S., Wang, D-Y., Chen, K-C., Tsai, S-T., Fang, S-Y., Huang, T-T., Wu, J-L., Wu, Y-H., Hsueh, W-T., Yen, C-J., Lai, Y-H., Liao, H. C., Wu, S-Y., Yang, M-W., Lin, F-C. & 6 others, Chang, J-Y., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Apr 21, In : BMC Cancer. 17, 1, 286.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Tobacco Products
Vegetables
Fruit
Logistic Models
2016
6 Citations (Scopus)

A comprehensive analysis on the association between tobacco-free betel quid and risk of head and neck cancer in Taiwanese men

Wu, Y-H., Yen, C-J., Hsiao, J-R., Ou, C-Y., Huang, J-S., Wang, D-Y., Tsai, S-T., Huang, C-C., Lee, W-T., Chen, K-C., Fang, S-Y., Wu, J-L., Hsueh, W-T., Lin, F-C., Yang, M-W., Chang, J-Y., Liao, H. C., Wu, S-Y., Lin, C. L., Wang, Y. H. & 4 others, Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2016 Oct 1, In : PLoS ONE. 11, 10, 0164937.

Research output: Contribution to journalArticle

betel
Tobacco
Head and Neck Neoplasms
Mastication
tobacco
4 Citations (Scopus)

Aligning to the sample-specific reference sequence to optimize the accuracy of next-generation sequencing analysis for hepatitis B virus

Liu, W. C., Lin, C. P., Cheng, C. P., Ho, C. H., Lan, K. L., Cheng, J. H., Yen, C-J., Cheng, P-N., Wu, I-C., Li, I. C., Chang, B. C. H., Tseng, V. S., Chiu, Y-C. & Chang, T-T., 2016 Jan 1, In : Hepatology International. 10, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Nucleotides
Genotype
Clone Cells
Nucleic Acid Databases
2 Citations (Scopus)

Allergy symptoms, serum total immunoglobulin E, and risk of head and neck cancer

Liao, H. C., Wu, S-Y., Ou, C-Y., Hsiao, J-R., Huang, J-S., Tsai, S-T., Huang, C-C., Wang, D-Y., Lee, W-T., Chen, K-C., Fang, S-Y., Wu, J-L., Huang, T-T., Wu, Y-H., Hsueh, W-T., Yen, C-J., Yang, M-W., Lin, F-C., Lai, Y-H., Chang, J-Y. & 6 others, Lin, C. L., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2016 Sep 1, In : Cancer Causes and Control. 27, 9, p. 1105-1115 11 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Immunoglobulin E
Hypersensitivity
Serum
Odds Ratio
25 Citations (Scopus)

Angiopoietin-like protein 1 antagonizes MET receptor activity to repress sorafenib resistance and cancer stemness in hepatocellular carcinoma

Chen, H. A., Kuo, T. C., Tseng, C. F., Ma, J. T., Yang, S. T., Yen, C-J., Yang, C. Y., Sung, S. Y. & Su, J. L., 2016 Nov 1, In : Hepatology. 64, 5, p. 1637-1651 15 p.

Research output: Contribution to journalArticle

Angiopoietins
Hepatocellular Carcinoma
Gastropoda
Neoplasms
Proteins
35 Citations (Scopus)

A randomized phase II study of FOLFOX with or without the MET inhibitor onartuzumab in advanced Adenocarcinoma of the stomach and Gastroesophageal junction

Shah, M. A., Cho, J. Y., Tan, I. B., Tebbutt, N. C., Yen, C-J., Kang, A., Shames, D. S., Bu, L. & Kang, Y. K., 2016 Sep 1, In : Oncologist. 21, 9, p. 1085-1090 6 p.

Research output: Contribution to journalArticle

Esophagogastric Junction
Stomach
Adenocarcinoma
Placebos
Population
15 Citations (Scopus)

HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3

Chen, J. Y., Chen, Y. J., Yen, C-J., Chen, W. S. & Huang, W. C., 2016 Jan 1, In : Oncotarget. 7, 1, p. 473-489 17 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Cell Survival
Up-Regulation
hepatitis B virus X protein
lapatinib
29 Citations (Scopus)

Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells

Chan, T. S., Hsu, C. C., Pai, V. C., Liao, W. Y., Huang, S. S., Tan, K. T., Yen, C-J., Hsu, S. C., Chen, W. Y., Shan, Y-S., Li, C. R., Lee, M. T., Jiang, K. Y., Chu, J. M., Lien, G. S., Weaver, V. M. & Tsai, K. K., 2016 Jan 1, In : Journal of Experimental Medicine. 213, 13, p. 2967-2988 22 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Drug Therapy
Neoplasms
Therapeutics
Chemokines
27 Citations (Scopus)

miR-106b promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma

Yen, C. S., Su, Z. R., Lee, Y. P., Liu, I-T. & Yen, C-J., 2016 Jun 14, In : World journal of gastroenterology. 22, 22, p. 5183-5192 10 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Neoplasms
MicroRNAs
Reverse Transcription