Chia-Yuan Chang

Assistant Professor

  • 505 Citations
  • 12 h-Index
20102019
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Research Output 2010 2019

  • 505 Citations
  • 12 h-Index
  • 28 Article
  • 13 Conference contribution
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Article
2019
1 Citation (Scopus)

A hydrolyzed chicken extract CMI-168 enhances learning and memory in middle-aged mice

Tsai, S. F., Chang, C. Y., Yong, S. M., Lim, A. L., Nakao, Y., Chen, S. J. & Kuo, Y. M., 2019 Jan, In : Nutrients. 11, 1, 27.

Research output: Contribution to journalArticle

Open Access
middle-aged adults
chicken meat
Meat
Chickens
ingredients
5 Citations (Scopus)

Pigment epithelium-derived factor inhibits lung cancer migration and invasion by upregulating exosomal thrombospondin 1

Huang, W. T., Chong, I. W., Chen, H. L., Li, C. Y., Hsieh, C. C., Kuo, H. F., Chang, C. Y., Chen, Y. H., Liu, Y. P., Lu, C. Y., Liu, Y. R. & Liu, P. L., 2019 Feb 1, In : Cancer Letters. 442, p. 287-298 12 p.

Research output: Contribution to journalArticle

Open Access
Thrombospondin 1
Exosomes
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Cell Movement

Simulation design of wide-field temporal-focusing multiphoton excitation with a tunable excitation wavelength

Lien, C. H., Lin, C. Y., Chang, C-Y. & Chien, F. C., 2019 Apr 15, In : OSA Continuum. 2, 4, p. 1174-1187 14 p.

Research output: Contribution to journalArticle

Wavelength
wavelengths
excitation
simulation
gratings
8 Citations (Scopus)

The sodium-glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats

Lee, H. C., Shiou, Y. L., Jhuo, S. J., Chang, C. Y., Liu, P. L., Jhuang, W. J., Dai, Z. K., Chen, W. Y., Chen, Y. F. & Lee, A. S., 2019 Apr 1, In : Cardiovascular Diabetology. 18, 1, 45.

Research output: Contribution to journalArticle

Open Access
Sodium-Glucose Transporter 2
Symporters
Fibrosis
Heart Failure
Hemodynamics
2018
7 Citations (Scopus)

Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

Wu, P. C., Wang, J. Y., Wang, W. L., Chang, C. Y., Huang, C. H., Yang, K. L., Chang, J. C., Hsu, C. L. L., Chen, S. Y., Chou, T. M. & Kuo, W. S., 2018 Jan 7, In : Nanoscale. 10, 1, p. 109-117 9 p.

Research output: Contribution to journalArticle

Graphite
Graphene
Semiconductor quantum dots
Luminescence
Polymers

Fast and improved bioimaging via temporal focusing multiphoton excitation microscopy with binary digital-micromirror-device holography

Sie, Y. D., Chang, C. Y., Lin, C. Y., Chang, N. S., Campagnola, P. J. & Chen, S. J., 2018 Jan 1, In : Journal of Biomedical Optics. 23, 11, 116502.

Research output: Contribution to journalArticle

Digital devices
Holography
holography
Microscopic examination
microscopy
3 Citations (Scopus)

Temporal focusing-based widefield multiphoton microscopy with spatially modulated illumination for biotissue imaging

Chang, C. Y., Lin, C. H., Lin, C. Y., Sie, Y. D., Hu, Y. Y., Tsai, S. F. & Chen, S. J., 2018 Jan, In : Journal of Biophotonics. 11, 1, e201600287.

Research output: Contribution to journalArticle

Lighting
Microscopy
Microscopic examination
Microscopes
illumination
2017
53 Citations (Scopus)

Graphene quantum dots with nitrogen-doped content dependence for highly efficient dual-modality photodynamic antimicrobial therapy and bioimaging

Kuo, W. S., Chen, H. H., Chen, S. Y., Chang, C. Y., Chen, P. C., Hou, Y. I., Shao, Y. T., Kao, H. F., Lilian Hsu, C. L., Chen, Y. C., Chen, S. J., Wu, S. R. & Wang, J. Y., 2017 Mar 1, In : Biomaterials. 120, p. 185-194 10 p.

Research output: Contribution to journalArticle

Quantum Dots
Graphite
Photochemotherapy
Graphene
Semiconductor quantum dots
2016
9 Citations (Scopus)

Fast volumetric imaging with patterned illumination via digital micro-mirror devicebased temporal focusing multiphoton microscopy

Chang, C. Y., Hu, Y. Y., Lin, C. Y., Lin, C. H., Chang, H. Y., Tsai, S. F., Lin, T. W. & Chen, S. J., 2016 May 1, In : Biomedical Optics Express. 7, 5, p. 1727-1736 10 p.

Research output: Contribution to journalArticle

Lighting
Microscopy
charge coupled devices
illumination
mirrors
1 Citation (Scopus)

Graphene oxide dot-based microstructures via dispersion and support of bovine serum albumin

Chang, H. Y., Lin, C. Y., Chang, C. Y., Teng, H., Campagnola, P. J. & Chen, S. J., 2016 Jan 1, In : Optical Materials Express. 6, 10, p. 3193-3201 9 p.

Research output: Contribution to journalArticle

Graphite
Bovine Serum Albumin
Oxides
Graphene
Microstructure
11 Citations (Scopus)

Graphene quantum dots conjugated with polymers for two-photon properties under two-photon excitation

Kuo, W. S., Hsu, C. L. L., Chen, H. H., Chang, C. Y., Kao, H. F., Chou, L. C. S., Chen, Y. C., Chen, S. J., Chang, W. T., Tseng, S. W., Wang, J. Y. & Pu, Y. C., 2016 Oct 14, In : Nanoscale. 8, 38, p. 16874-16880 7 p.

Research output: Contribution to journalArticle

Graphite
Graphene
Semiconductor quantum dots
Polymers
Photons
25 Citations (Scopus)

Two-Photon Photoexcited Photodynamic Therapy and Contrast Agent with Antimicrobial Graphene Quantum Dots

Kuo, W. S., Chang, C. Y., Chen, H. H., Hsu, C. L. L., Wang, J. Y., Kao, H. F., Chou, L. C. S., Chen, Y. C., Chen, S. J., Chang, W. T., Tseng, S. W., Wu, P. C. & Pu, Y. C., 2016 Nov 9, In : ACS Applied Materials and Interfaces. 8, 44, p. 30467-30474 8 p.

Research output: Contribution to journalArticle

Photodynamic therapy
Graphite
Graphene
Contrast Media
Semiconductor quantum dots
2015
6 Citations (Scopus)

Effect of Size-Dependent Photodestructive Efficacy by Gold Nanomaterials with Multiphoton Laser

Chang, W-T., Chen, S. J., Chang, C-Y., Liu, Y. H., Chen, C. H., Yang, C. H., Chou, L. C. S., Chang, J. C., Cheng, L. C., Kuo, W. S. & Wang, J-Y., 2015 Aug 12, In : ACS Applied Materials and Interfaces. 7, 31, p. 17318-17329 12 p.

Research output: Contribution to journalArticle

Nanostructured materials
Gold
Lasers
Photons
Cells
4 Citations (Scopus)

High-throughput multiphoton-induced threedimensional ablation and imaging for biotissues

Lin, C. Y., Li, P. K., Cheng, L. C., Li, Y. C., Chang, C. Y., Chiang, A. S., Dong, C. Y. & Chen, S. J., 2015 Jan 1, In : Biomedical Optics Express. 6, 2, p. 491-499 9 p.

Research output: Contribution to journalArticle

ablation
tendons
chickens
Optical Imaging
Laser Therapy
8 Citations (Scopus)

Neurodegeneration in Amygdala precedes hippocampus in the APPswe/PS1dE9 mouse model of Alzheimer’s disease

Lin, T. W., Liu, Y. F., Shih, Y. H., Chen, S. J., Huang, T. Y., Chang, C-Y., Lien, C. H., Yu, L., Chen, S. & Kuo, Y-M., 2015 Dec 1, In : Current Alzheimer research. 12, 10, p. 951-963 13 p.

Research output: Contribution to journalArticle

Amygdala
Hippocampus
Alzheimer Disease
Transgenic Mice
Neurons
56 Citations (Scopus)

Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice

Lin, T. W., Shih, Y. H., Chen, S. J., Lien, C. H., Chang, C. Y., Huang, T. Y., Chen, S. H., Jen, C. J. & Kuo, Y. M., 2015 Feb 1, In : Neurobiology of Learning and Memory. 118, p. 189-197 9 p.

Research output: Contribution to journalArticle

Amygdala
Running
Transgenic Mice
Hippocampus
Alzheimer Disease
2014
9 Citations (Scopus)

Graphene oxide-based micropatterns via highthroughput multiphoton-induced reduction and ablation

Li, Y. C., Yeh, T. F., Huang, H. C., Chang, H. Y., Lin, C. Y., Cheng, L. C., Chang, C. Y., Teng, H. & Chen, S. J., 2014 Aug 11, In : Optics Express. 22, 16, p. 19726-19734 9 p.

Research output: Contribution to journalArticle

ablation
graphene
oxides
lasers
oxide films
24 Citations (Scopus)

Social instability stress differentially affects amygdalar neuron adaptations and memory performance in adolescent and adult rats

Tsai, S. F., Huang, T. Y., Chang, C. Y., Hsu, Y. C., Chen, S. J., Yu, L., Kuo, Y. M. & Jen, C. J., 2014 Feb 3, In : Frontiers in Behavioral Neuroscience. 8, FEB, 27.

Research output: Contribution to journalArticle

Amygdala
Neurons
Startle Reflex
Fear
Dendritic Spines
16 Citations (Scopus)

Wavefront sensorless adaptive optics temporal focusing-based multiphoton microscopy

Chang, C. Y., Cheng, L. C., Su, H. W., Hu, Y. Y., Cho, K. C., Yen, W. C., Xu, C., Dong, C. Y. & Chen, S. J., 2014 Jun 1, In : Biomedical Optics Express. 5, 6, p. 1768-1777 10 p., A1768.

Research output: Contribution to journalArticle

Photons
adaptive optics
Microscopy
Fluorescence
microscopy
2013
5 Citations (Scopus)

Easily implementable field programmable gate array-based adaptive optics system with state-space multichannel control

Chang, C. Y., Ke, B. T., Su, H. W., Yen, W. C. & Chen, S. J., 2013 Sep 1, In : Review of Scientific Instruments. 84, 9, 095112.

Research output: Contribution to journalArticle

field-programmable gate arrays
Adaptive optics
adaptive optics
Field programmable gate arrays (FPGA)
Wavefronts
9 Citations (Scopus)

High-throughput fabrication of gray-level biomicrostructures via temporal focusing excitation and laser pulse control

Li, Y. C., Cheng, L. C., Chang, C. Y., Lin, C. Y., Chang, N. S., Campagnola, P. J., Dong, C. Y. & Chen, S. J., 2013 Jul 1, In : Journal of Biomedical Optics. 18, 7, 075004.

Research output: Contribution to journalArticle

Rose Bengal
Bovine Serum Albumin
albumins
serums
Laser pulses
2012
62 Citations (Scopus)

Different types of exercise induce differential effects on neuronal adaptations and memory performance

Lin, T. W., Chen, S. J., Huang, T. Y., Chang, C. Y., Chuang, J. I., Wu, F. S., Kuo, Y. M. & Jen, C. J., 2012 Jan 1, In : Neurobiology of Learning and Memory. 97, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

Running
Amygdala
Hippocampus
Neuronal Plasticity
Learning
42 Citations (Scopus)

Fast multiphoton microfabrication of freeform polymer microstructures by spatiotemporal focusing and patterned excitation

Li, Y. C., Cheng, L. C., Chang, C. Y., Lien, C. H., Campagnola, P. J. & Chen, S. J., 2012 Aug 13, In : Optics Express. 20, 17, p. 19030-19038 9 p.

Research output: Contribution to journalArticle

microstructure
polymers
excitation
fabrication
scanning
15 Citations (Scopus)

Investigation of two-photon excited fluorescence increment via crosslinked bovine serum albumin

Lin, C. Y., Lien, C. H., Cho, K. C., Chang, C. Y., Chang, N. S., Campagnola, P. J., Dong, C. Y. & Chen, S. J., 2012 Jun 18, In : Optics Express. 20, 13, p. 13669-13676 8 p.

Research output: Contribution to journalArticle

albumins
serums
fluorescence
decay rates
photons
61 Citations (Scopus)

Spatiotemporal focusing-based widefield multiphoton microscopy for fast optical sectioning

Cheng, L. C., Chang, C. Y., Lin, C. Y., Cho, K. C., Yen, W. C., Chang, N. S., Xu, C., Dong, C. Y. & Chen, S. J., 2012 Apr 9, In : Optics Express. 20, 8, p. 8939-8948 10 p.

Research output: Contribution to journalArticle

microscopes
microscopy
tendons
chickens
excitation
2011
15 Citations (Scopus)

Enhanced two-photon excited fluorescence in three-dimensionally crosslinked bovine serum albumin microstructures

Cho, K. C., Lien, C. H., Lin, C. Y., Chang, C. Y., Huang, L. L. H., Campagnola, P. J., Dong, C. Y. & Chen, S. J., 2011 Jun 6, In : Optics Express. 19, 12, p. 11732-11739 8 p.

Research output: Contribution to journalArticle

albumins
serums
fluorescence
microstructure
photons
2010
25 Citations (Scopus)

Multiphoton fabrication of freeform polymer microstructures with gold nanorods

Kuo, W. S., Lien, C. H., Cho, K. C., Chang, C. Y., Lin, C. Y., Huang, L. L. H., Campagnola, P. J., Dong, C. Y. & Chen, S. J., 2010 Dec 20, In : Optics Express. 18, 26, p. 27550-27559 10 p.

Research output: Contribution to journalArticle

nanorods
gold
microstructure
fabrication
polymers
21 Citations (Scopus)

Surface plasmon-enhanced and quenched two-photon excited fluorescence

Lin, C. Y., Chiu, K. C., Chang, C-Y., Chang, S., Guo, T-F. & Chen, S. J., 2010 Jun 7, In : Optics Express. 18, 12, p. 12807-12817 11 p.

Research output: Contribution to journalArticle

fluorescence
photons
augmentation
plasmons
spacers