• 385 Citations
  • 10 h-Index
20102019
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Personal profile

Education

  • 2011 PhD, Department of Molecular Genetics, Leiden Institute of Chemistry, Leiden University, The Netherlands

Experience

  • 2012/01 ~ 2012/12 Postdoctoral Fellow, Department of Molecular Genetics, Leiden Institute of Chemistry, Leiden University, The Netherlands
  • 2013/05 ~ 2016/12 Postdoctoral Fellow, Department of Physiology, UT Southwestern Medical Center, USA
  • 2017/02 ~ present Assistant Professor, Department of Biochemisty and Molecular Biology, Collge of Medicine, National Cheng Kung University

Research Interests

  • codon usage bias-regulated gene expression
  • regulation of protein translation
  • RNA biology

Fingerprint Dive into the research topics where Chien-hung Yu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Ribosomal Frameshifting Medicine & Life Sciences
Codon Medicine & Life Sciences
Riboswitch Medicine & Life Sciences
Protein Biosynthesis Medicine & Life Sciences
RNA Medicine & Life Sciences
Amyloid Chemical Compounds
Peptides Chemical Compounds
Gene Expression Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2017 2018

Research Output 2010 2019

  • 385 Citations
  • 10 h-Index
  • 11 Article
  • 1 Chapter

eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons

Yang, Q., Yu, C. H., Zhao, F., Dang, Y., Wu, C., Xie, P., Sachs, M. S. & Liu, Y., 2019 Sep 26, In : Nucleic acids research. 47, 17, p. 9243-9258 16 p.

Research output: Contribution to journalArticle

Open Access
Protein Biosynthesis
Codon
Ribosomes
Neurospora
Proteins
14 Citations (Scopus)

Codon usage regulates protein structure and function by affecting translation elongation speed in Drosophila cells

Zhao, F., Yu, C. & Liu, Y., 2017 Jan 1, In : Nucleic acids research. 45, 14, p. 8484-8492 9 p.

Research output: Contribution to journalArticle

Codon
Drosophila
Proteins
Protein Biosynthesis
Cell-Free System
51 Citations (Scopus)

Codon usage is an important determinant of gene expression levels largely through its effects on transcription

Zhoua, Z., Danga, Y., Zhou, M., Li, L., Yu, C., Fu, J., Chen, S. & Liu, Y., 2016 Oct 11, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 41, p. E6117-E6125

Research output: Contribution to journalArticle

Codon
Gene Expression
Protein Biosynthesis
Genome
Neurospora
137 Citations (Scopus)

Codon Usage Influences the Local Rate of Translation Elongation to Regulate Co-translational Protein Folding

Yu, C., Dang, Y., Zhou, Z., Wu, C., Zhao, F., Sachs, M. S. & Liu, Y., 2015 Sep 3, In : Molecular Cell. 59, 5, p. 744-754 11 p.

Research output: Contribution to journalArticle

Protein Folding
Codon
Ribosomes
Messenger RNA
Neurospora
2 Citations (Scopus)

Monitoring ribosomal frameshifting as a platform to screen anti-riboswitch drug candidates

Yu, C. & Olsthoorn, R. C. L., 2015 Jan 1, Methods in Enzymology. Academic Press Inc., p. 385-393 9 p. (Methods in Enzymology; vol. 550).

Research output: Chapter in Book/Report/Conference proceedingChapter

Ribosomal Frameshifting
Riboswitch
Monitoring
Pharmaceutical Preparations
Screening