• 412 Citations
  • 10 h-Index
20102019
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Research Output 2010 2019

  • 412 Citations
  • 10 h-Index
  • 11 Article
  • 1 Chapter
2019

eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons

Yang, Q., Yu, C. H., Zhao, F., Dang, Y., Wu, C., Xie, P., Sachs, M. S. & Liu, Y., 2019 Sep 26, In : Nucleic acids research. 47, 17, p. 9243-9258 16 p.

Research output: Contribution to journalArticle

Open Access
Protein Biosynthesis
Codon
Ribosomes
Neurospora
Proteins
2017
15 Citations (Scopus)

Codon usage regulates protein structure and function by affecting translation elongation speed in Drosophila cells

Zhao, F., Yu, C. H. & Liu, Y., 2017 Jan 1, In : Nucleic acids research. 45, 14, p. 8484-8492 9 p.

Research output: Contribution to journalArticle

Codon
Drosophila
Proteins
Protein Biosynthesis
Cell-Free System
2016
53 Citations (Scopus)

Codon usage is an important determinant of gene expression levels largely through its effects on transcription

Zhoua, Z., Danga, Y., Zhou, M., Li, L., Yu, C., Fu, J., Chen, S. & Liu, Y., 2016 Oct 11, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 41, p. E6117-E6125

Research output: Contribution to journalArticle

Codon
Gene Expression
Protein Biosynthesis
Genome
Neurospora
2015
154 Citations (Scopus)

Codon Usage Influences the Local Rate of Translation Elongation to Regulate Co-translational Protein Folding

Yu, C., Dang, Y., Zhou, Z., Wu, C., Zhao, F., Sachs, M. S. & Liu, Y., 2015 Sep 3, In : Molecular Cell. 59, 5, p. 744-754 11 p.

Research output: Contribution to journalArticle

Protein Folding
Codon
Ribosomes
Messenger RNA
Neurospora
2 Citations (Scopus)

Monitoring ribosomal frameshifting as a platform to screen anti-riboswitch drug candidates

Yu, C. & Olsthoorn, R. C. L., 2015 Jan 1, Methods in Enzymology. Academic Press Inc., p. 385-393 9 p. (Methods in Enzymology; vol. 550).

Research output: Chapter in Book/Report/Conference proceedingChapter

Ribosomal Frameshifting
Riboswitch
Monitoring
Pharmaceutical Preparations
Screening
2014
34 Citations (Scopus)

Stimulation of ribosomal frameshifting by RNA G-quadruplex structures

Yu, C. H., Teulade-Fichou, M. P. & Olsthoorn, R. C. L., 2014 Feb 1, In : Nucleic acids research. 42, 3, p. 1887-1892 6 p.

Research output: Contribution to journalArticle

Ribosomal Frameshifting
G-Quadruplexes
Ribosomal RNA
RNA
Terminator Codon
24 Citations (Scopus)

The Aβ peptide forms non-amyloid fibrils in the presence of carbon nanotubes

Luo, J., Wärmländer, S. K. T. S., Yu, C., Muhammad, K., Gräslund, A. & Pieter Abrahams, J., 2014 Jun 21, In : Nanoscale. 6, 12, p. 6720-6726 7 p.

Research output: Contribution to journalArticle

Carbon Nanotubes
Peptides
Carbon nanotubes
Poisons
Single-walled carbon nanotubes (SWCN)
2013
49 Citations (Scopus)

Cellular polyamines promote amyloid-Beta (Aβ) peptide fibrillation and modulate the aggregation pathways

Luo, J., Yu, C. H., Yu, H., Borstnar, R., Kamerlin, S. C. L., Gräslund, A., Abrahams, J. P. & Wärmländer, S. K. T. S., 2013 Mar 20, In : ACS Chemical Neuroscience. 4, 3, p. 454-462 9 p.

Research output: Contribution to journalArticle

Amyloid beta-Peptides
Polyamines
Amyloid
Agglomeration
Peptides
10 Citations (Scopus)

Exploiting preQ1 riboswitches to regulate ribosomal frameshifting

Yu, C., Luo, J., Iwata-Reuyl, D. & Olsthoorn, R. C. L., 2013 Apr 19, In : ACS Chemical Biology. 8, 4, p. 733-740 8 p.

Research output: Contribution to journalArticle

Ribosomal Frameshifting
Riboswitch
Assays
Fusobacterium nucleatum
Ligands
24 Citations (Scopus)

Inhibiting and reversing amyloid-β peptide (1-40) fibril formation with Gramicidin S and engineered analogues

Luo, J., Otero, J. M., Yu, C., Wärmländer, S. K. T. S., Gräslund, A., Overhand, M. & Abrahams, J. P., 2013 Dec 16, In : Chemistry - A European Journal. 19, 51, p. 17338-17348 11 p.

Research output: Contribution to journalArticle

Gramicidin
Amyloid
Peptides
Antibiotics
Deposits
2011
26 Citations (Scopus)

Stem-loop structures can effectively substitute for an RNA pseudoknot in -1 ribosomal frameshifting

Yu, C., Noteborn, M. H., Pleij, C. W. A. & Olsthoorn, R. C. L., 2011 Nov 1, In : Nucleic acids research. 39, 20, p. 8952-8959 8 p.

Research output: Contribution to journalArticle

Mason-Pfizer monkey virus
Ribosomal Frameshifting
RNA
Polyproteins
Base Composition
2010
21 Citations (Scopus)

Stimulation of ribosomal frameshifting by antisense LNA

Yu, C., Noteborn, M. H. M. & Olsthoorn, R. C. L., 2010 Dec 1, In : Nucleic acids research. 38, 22, p. 8277-8283 7 p.

Research output: Contribution to journalArticle

Ribosomal Frameshifting
Oligonucleotides
Acids
RNA
Antisense Oligonucleotides