Chih-Hung Chen

Associate Professor

  • 1439 Citations
  • 22 h-Index
19972020

Research output per year

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Research Output

  • 1439 Citations
  • 22 h-Index
  • 73 Article
  • 5 Letter
  • 1 Conference contribution
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Article

4G/5G promoter polymorphism of plasminogen activator inhibitor-1, lipid profiles, and ischemic stroke

Chen, C-H., Eng, H. L., Chang, C-J., Tsai, T., Lai, M. L., Chen, H. Y., Liu, C. J. & Lin, T. M., 2003 Aug 1, In : Journal of Laboratory and Clinical Medicine. 142, 2, p. 100-105 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

A CD14 monocyte receptor polymorphism and genetic susceptibility to Parkinson's disease for females

Lin, J. J., Chen, C-H., Yueh, K. C., Chang, C. Y. & Lin, S. Z., 2006 Jan 1, In : Parkinsonism and Related Disorders. 12, 1, p. 9-13 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

A CD14 promoter polymorphism is associated with CD14 expression and Chlamydia-stimulated TNFα production

Eng, H. L., Wang, C. H., Chen, C. H., Chou, M. H., Cheng, C. T. & Lin, T. M., 2004 Aug 1, In : Genes and Immunity. 5, 5, p. 426-430 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Acute aortic dissection mimicking basilar artery occlusion in a patient presenting with sudden coma

Sung, P-S., Fang, C. W. & Chen, C-H., 2010 Jul 1, In : Journal of Clinical Neuroscience. 17, 7, p. 952-953 2 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Ambient temperature and spontaneous intracerebral haemorrhage: A crosssectional analysis in Tainan, Taiwan

Fang, C. W., Ma, M. C., Lin, H. J. & Chen, C. H., 2012 Jul 16, In : BMJ open. 2, 3, e000842.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A novel platelet-rich arterial thrombosis model in rabbits: Simple, reproducible, and dynamic real-time measurement by using double-opposing inverted-sutures model

Shieh, S-J., Chiu, H. Y., Shi, G. Y., Wu, C. M., Wang, J. C., Chen, C-H. & Wu, H-L., 2001 Sep 1, In : Thrombosis Research. 103, 5, p. 363-376 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Apolipoprotein B gene polymorphisms in Taiwanese ischemic stroke patients

Chen, C-H., Lai, M. L., Lai, M-D. & Huang, J. D., 1997 Jul 1, In : Journal of the Formosan Medical Association. 96, 7, p. 499-502 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Association of CD14 promoter gene polymorphism and Chlamydia pneumoniae infection

Eng, H. L., Chen, C. H., Kuo, C. C., Wu, J. S., Wang, C. H. & Lin, T. M., 2003 Jul 1, In : Journal of Infectious Diseases. 188, 1, p. 90-97 8 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
4 Citations (Scopus)

Cholesterol Levels Are Associated with 30-day Mortality from Ischemic Stroke in Dialysis Patients

Wang, I. K., Liu, C. H., Yen, T. H., Jeng, J. S., Hsu, S. P., Chen, C. H., Lien, L. M., Lin, R. T., Chen, A. C., Lin, H. J., Chi, H. Y., Lai, T. C., Sun, Y., Lee, S. P., Sung, S. F., Chen, P. L., Lee, J. T., Chiang, T. R., Lin, S. K., Muo, C. H. & 235 others, Ma, H., Wen, C. P., Sung, F. C., Hsu, C. Y., Tsai, C. H., Huang, W. S., Lu, C. T., Tsai, T. C., Tseng, C. H., Lin, K. H., Shyn, W. C., Yang, Y. W., Liu, Y. L., Cho, D. Y., Chen, C. C., Tang, S. C., Tsai, L. K., Yeh, S. J., Chen, H. J., Chang, C. S., Kuo, H. C., Lee, L. H., Tsui, H. W., Tsou, J. C., Wang, Y. T., Tai, Y. C., Tsai, K. C., Chen, Y. W., Lu, K., Liliang, P. C., Tsai, Y. T., Liang, C. L., Wang, K. W., Wang, H. K., Chen, J. S., Chen, P. Y., Chye, C. L., Tzeng, W. J., Wu, P. H., Sung, P. S., Hsieh, H. C., Su, H. C., Chiu, H. C., Chen, W. H., Bai, C. H., Huang, T. H., Lau, C. I., Wu, Y. Y., Yeh, H. L., Chang, A., Lin, C. H., Yen, C. C., Khor, G. T., Chao, A. C., Lin, H. F., Huang, P., Ke, D. S., Chang, C. Y., Yeh, P. S., Lin, K. C., Cheng, T. J., Chou, C. H., Yang, C. M., Shen, H. C., Tsai, S. J., Lu, T. M., Kung, S. L., Lee, M. J., Chou, H. H., Pan, C. H., Chan, P. C., Hsu, M. H., Chang, W. L., Huang, Z. Z., Shoung, H. M., Lo, Y. C., Wang, F. H., Yin, J. H., Wang, C. J., Wang, K. C., Chen, L. M., Denq, J. C., Lu, C. J., Huang, C. C., Chan, H. F., Sun, M. H., Ke, L. Y., Lee, Y. S., Ong, C. T., Wu, C. S., Hsu, Y. C., Su, Y. H., Hung, L. C., Lin, J. C., Hsu, Y. D., Peng, G. S., Hsu, C. H., Lin, C. C., Yen, C. H., Cheng, C. A., Sung, Y. F., Chen, Y. L., Lien, M. T., Liu, C. C., Yang, F. C., Wu, Y. C., Tso, A. C., Lai, Y. H., Chiang, C. I., Tsai, C. K., Liu, M. T., Lin, Y. C., Hsu, Y. C., Lee, M. C., Huang, P. H., Lie, S. K., Liao, P. W., Chen, J. T., Sun, M. C., Lai, T. P., Chen, W. L., Chen, Y. C., Chen, T. C., Wang, W. F., Lee, K. W., Lai, C. H., Shih, S. Y., Chuang, C. S., Chen, Y. Y., Chen, C. M., Su, Y. C., Hsiao, C. L., Yang, F. Y., Liu, C. Y., Chiang, H. L., Lin, I. S., Chien, C. H., Chang, Y. C., Chen, P. K., Chiu, P. Y., Hsiao, Y. J., Fang, C. W., Lee, K. Y., Lin, Y. Y., Li, C. H., Tsai, H. F., Hsieh, C. F., Yang, C. D., Liaw, S. J., Liao, H. C., Wu, L. L., Hsieh, L. P., Lee, Y. H., Chen, C. W., Hsu, C. S., Jhih, Y. J., Zhuang, H. Y., Pan, Y. H., Shih, S. A., Chen, C. I., Sung, J. Y., Weng, H. Y., Teng, H. W., Lee, J. E., Huang, C. S., Chao, S. P., Yuan, R. Y., Sheu, J. J., Yu, J. M., Ho, C. S., Lin, T. C., Yu, S. C., Chen, J. R., Tsai, S. Y., Wei, C. Y., Yang, C. N., Hung, C. H., Shih, I., Tseng, H. P., Lin, C. L., Lin, H. C., Chen, P. T., Hu, C. J., Chi, N. F., Chan, L., Chern, C. M., Lin, C. J., Wang, S. J., Hsu, L. C., Wong, W. J., Lee, I. H., Yen, D. J., Tsai, C. P., Kwan, S. Y., Soong, B. W., Chen, S. P., Liao, K. K., Lin, K. P., Chen, C., Shan, D. E., Fuh, J. L., Wang, P. N., Lee, Y. C., Yu, Y. H., Huang, H. C., Tsai, J. Y., Wu, M. H., Chen, S. C., Chiang, S. Y., Wang, C. Y., Hsu, M. C., Yeh, P. Y., Wang, K. Y., Chen, T. S., Yip, P. K., Wang, V., Tsai, C. F., Liu, Y. C., Chen, S. Y., Zhao, Z. H., Wei, Z. P., Wu, S. L., Liu, C. K., Lin, R. H., Chu, C. H., Yan, S. H., Hsiao, S. H., Yip, B. S., Tsai, P. C., Chou, P. C., Kuo, T. M., Chiu, Y. P., Liao, Y. S., Tsai, M. J. & Kao, H. Y., 2017 Jun, In : Journal of Stroke and Cerebrovascular Diseases. 26, 6, p. 1349-1356 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
14 Citations (Scopus)

Comparative outcomes between hemo- and peritoneal dialysis patients with acute intracerebral hemorrhage

Hsieh, C. Y., Chen, C. H., Wu, A. B. & Tseng, C. C., 2010 Jul 1, In : American Journal of Nephrology. 32, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Comparison between aspirin and clopidogrel in secondary stroke prevention based on real-world data

Taiwan Stroke Registry Investigators, 2018 Oct 1, In : Journal of the American Heart Association. 7, 19, e009856.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Comparison of risk-scoring systems in predicting symptomatic intracerebral hemorrhage after intravenous thrombolysis

Sung, S. F., Chen, S. C. C., Lin, H. J., Chen, Y. W., Tseng, M. C. & Chen, C. H., 2013 Jun 1, In : Stroke. 44, 6, p. 1561-1566 6 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Delayed Trigeminal Motor Denervation after Pontine Hemorrhage

Chao, L-C., Abbasali Tailor, A. R., Chen, C-H. & Lee, J-S., 2015 Sep 1, In : Journal of Stroke and Cerebrovascular Diseases. 24, 9, p. e261-e263

Research output: Contribution to journalArticle

Developing a stroke severity index based on administrative data was feasible using data mining techniques

Sung, S. F., Hsieh, C. Y., Kao, Y-H., Lin, H. J., Chen, C-H., Chen, Y. W. & Hu, Y. H., 2015 Nov 1, In : Journal of Clinical Epidemiology. 68, 11, p. 1292-1300 9 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
8 Citations (Scopus)

Different doses of recombinant tissue-type plasminogen activator for acute stroke in Chinese patients

Chao, A. C., Liu, C. K., Chen, C. H., Lin, H. J., Liu, C. H., Jeng, J. S., Hu, C. J., Chung, C. P., Hsu, H. Y., Sheng, W. Y. & Hu, H. H., 2014 Aug, In : Stroke. 45, 8, p. 2359-2365 7 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
6 Citations (Scopus)

Effect of duration of osmotherapy on blood-brain barrier disruption and regional cerebral edema after experimental stroke

Chen, C. H., Toung, T. J. K., Sapirstein, A. & Bhardwaj, A., 2006 Jun 19, In : Journal of Cerebral Blood Flow and Metabolism. 26, 7, p. 951-958 8 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Effect of osmotherapy with hypertonic saline on regional cerebral edema following experimental stroke: A study utilizing magnetic resonance imaging

Chen, C-H., Xue, R., Zhang, J., Li, X., Mori, S. & Bhardwaj, A., 2007 Aug 1, In : Neurocritical Care. 7, 1, p. 92-100 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Efforts to reduce the door-to-needle time of thrombolysis in acute ischemic stroke: Video-assisted therapeutic risk communication

Hsieh, C. Y., Chen, W. F., Chen, C. H., Wang, C. Y., Chen, C. J., Lai, E. C. C. & Chen, T. S., 2014 Dec 1, In : Journal of the Formosan Medical Association. 113, 12, p. 929-933 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Epistasis Analysis for Estrogen Metabolic and Signaling Pathway Genes on Young Ischemic Stroke Patients

Hsieh, Y. C., Jeng, J. S., Lin, H. J., Hu, C. J., Yu, C. C., Lien, L. M., Peng, G. S., Chen, C. I. C. I., Tang, S. C., Chi, N. F., Tseng, H. P., Chern, C. M., Hsieh, F. I. F. I., Bai, C. H., Chen, Y. R., Chiou, H. Y., Yeh, S. J., Tsai, L. K., Kong, S., Chiu, H. C. & 52 others, Chen, W. H., Huang, T. H., Lau, C. I., Wu, Y. Y., Yuan, R. Y., Sheu, J. J., Yu, J. M., Ho, C. S., Chen, C. I., Sung, J. Y., Weng, H. Y., Han, Y. H., Huang, C. P., Chung, W. T., Ke, D. S., Chang, C. Y., Yeh, P. S., Lin, K. C., Cheng, T. J., Chou, C. H., Yang, C. M., Lin, J. C., Hsu, Y. D., Denq, J. C., Lee, J. T., Hsu, C. H., Lin, C. C., Yen, C. H., Cheng, C. A., Sung, Y. F., Chen, Y. L., Lien, M. T., Liu, C. C., Yang, F. C., Wu, Y. C., Tso, A. C., Lai, Y. H., Chiang, C. I., Tsai, C. K., Liu, M. T., Lin, Y. C., Hsu, Y. C., Chen, C. H., Sung, P. S., Hu, H. H., Wong, W. J., Luk, Y. O., Hsu, L. C., Chung, C. P., Liu, C. H., Lin, C. L. & Lin, H. C., 2012 Oct 24, In : PloS one. 7, 10, e47773.

Research output: Contribution to journalArticle

8 Citations (Scopus)
16 Citations (Scopus)
8 Citations (Scopus)

Functional mutation in the promoter region of thrombomodulin gene in relation to carotid atherosclerosis

Li, Y. H., Chen, C. H., Yeh, P. S., Lin, H. J., Chang, B. I., Lin, J. C., Guo, H. R., Wu, H. L., Shi, G. Y., Lai, M. L. & Chen, J. H., 2001 Feb 15, In : Atherosclerosis. 154, 3, p. 713-719 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Get with the guidelines-stroke performance indicators: Surveillance of Stroke Care in the Taiwan Stroke Registry: Get with the guidelines-stroke in Taiwan

Hsieh, F. I., Lien, L. M., Chen, S. T., Bai, C. H., Sun, M. C., Tseng, H. P., Chen, Y. W., Chen, C. H., Jeng, J. S., Tsai, S. Y., Lin, H. J., Liu, C. H., Lo, Y. K., Chen, H. J., Chiu, H. C., Lai, M. L., Lin, R. T., Sun, M. H., Yip, B. S., Chiou, H. Y. & 1 others, Hsu, C. Y., 2010 Sep 14, In : Circulation. 122, 11, p. 1116-1123 8 p.

Research output: Contribution to journalArticle

159 Citations (Scopus)

Homozygous deletion genotype of angiotensin converting enzyme confers protection against migraine in man

Lin, J. J., Wang, P. J., Chen, C-H., Yueh, K. C., Lin, S. Z. & Harn, H. J., 2005 Sep 1, In : Acta Neurologica Taiwanica. 14, 3, p. 120-125 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Hyperglycemia predicts unfavorable outcomes in acute ischemic stroke patients treated with intravenous thrombolysis among a Chinese population: A prospective cohort study

Taiwan Thrombolytic Therapy for Acute Ischemic Stroke (TTT-AIS) Study Group, 2018 May 15, In : Journal of the Neurological Sciences. 388, p. 195-202 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Impact of MCA stenosis on the early outcome in acute ischemic stroke patients

Jeng, J. S., Hsieh, F. I., Yeh, H. L., Chen, W. H., Chiu, H. C., Tang, S. C., Liu, C. H., Lin, H. J., Hsu, S. P., Lo, Y. K., Chan, L., Chen, C. H., Lin, R. T., Chen, Y. W., Lee, J. T., Yeh, C. H., Sun, M. H., Lai, T. C., Sun, Y., Sun, M. C. & 10 others, Chen, P. L., Chiang, T. R., Lin, S. K., Yip, B. S., Chen, C. I., Bai, C. H., Chen, S. T., Chiou, H. Y., Lien, L. M. & Hsu, C. Y., 2017 Apr, In : PloS one. 12, 4, e0175434.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Increased risk of dementia in patients with non-apnea sleep disorder

Sung, P-S., Yeh, C. C., Wang, L-C., Hung, P. H., Muo, C. H., Sung, F. C., Chen, C-H. & Tsai, K-J., 2017 Mar 1, In : Current Alzheimer research. 14, 3, p. 309-316 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
67 Citations (Scopus)

Intravenous thrombolysis administration 3–4.5 h after acute ischemic stroke: A retrospective, multicenter study

Chen, Y. W., Sung, S. F., Chen, C. H., Tang, S. C., Tsai, L. K., Lin, H. J., Huang, H. Y., Po, H. L., Sun, Y., Chen, P. L., Chan, L., Wei, C. Y., Lee, J. T., Hsieh, C. Y., Lin, Y. Y., Yeh, S. J., Lien, L. M. & Jeng, J. S., 2019 Jan 1, In : Frontiers in Neurology. 10, OCT, 1038.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Ischemic neuroprotection with selective κ-opioid receptor agonist is gender specific

Chen, C. H., Toung, T. J. K., Hum, P. D., Koehler, R. C. & Bhardwaj, A., 2005 Jul 1, In : Stroke. 36, 7, p. 1557-1561 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Isolated brainstem involvement in a patient with hypertensive encephalopathy

Hsieh, C. Y., Chen, C-H. & Chang, T. P., 2010 Mar 1, In : Acta Neurologica Taiwanica. 19, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Is renal dysfunction associated with adverse stroke outcome after thrombolytic therapy?

Hsieh, C. Y., Lin, H. J., Sung, S. F., Hsieh, H. C., Lai, E. C. C. & Chen, C. H., 2014 Jan 1, In : Cerebrovascular Diseases. 37, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Leukoaraiosis and risk of intracranial hemorrhage and outcome after stroke thrombolysis

Yang, C. M., Hung, C. L., Su, H. C., Lin, H. J., Chen, C. H., Lin, C. C., Hu, H. H., Lin, S. H. & Sung, P. S., 2018 May, In : PloS one. 13, 5, e0196505.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Low cholesterol level associated with severity and outcome of spontaneous intracerebral hemorrhage: Results from Taiwan Stroke Registry

Chen, Y. W., Li, C. H., Yang, C. D., Liu, C. H., Chen, C. H., Sheu, J. J., Lin, S. K., Chen, A. C., Chen, P. K., Chen, P. L., Yeh, C. H., Chen, J. R., Hsiao, Y. J., Lin, C. H., Hsu, S. P., Chen, T. S., Sung, S. F., Yu, S. C., Muo, C. H., Wen, C. P. & 3 others, Sung, F. C., Jeng, J. S. & Hsu, C. Y., 2017 Apr, In : PloS one. 12, 4, e0171379.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Low cholesterol levels increase symptomatic intracranial hemorrhage rates after intravenous thrombolysis: A multicenter cohort validation study

Taiwan Thrombolytic Therapy for Acute Ischemic Stroke (TTT-AIS) Study Group, 2019 Jan 1, In : Journal of Atherosclerosis and Thrombosis. 26, 6, p. 513-527 15 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Low-dose versus standard-dose intravenous alteplase for octogenerian acute ischemic stroke patients: A multicenter prospective cohort study

On behalf of the Taiwan Thrombolytic Therapy for Acute Ischemic Stroke (TTT-AIS) Study Group, 2019 Apr 15, In : Journal of the Neurological Sciences. 399, p. 76-81 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Low estimated glomerular filtration rate is associated with poor outcomes in patients who suffered a large artery atherosclerosis stroke

Yeh, S. J., Jeng, J. S., Tang, S. C., Liu, C. H., Hsu, S. P., Chen, C. H., Lien, L. M., Lin, H. J., Chen, C. M., Lin, R. T., Lee, S. P., Lin, C. H., Yeh, C. H., Sun, Y., Sun, M. H., Yin, J. H., Lin, C. C., Wen, C. P., Tsai, L. K., Sung, F. C. & 1 others, Hsu, C. Y., 2015 Apr 1, In : Atherosclerosis. 239, 2, p. 328-334 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Low Pulse Pressure After Acute Ischemic Stroke is Associated With Unfavorable Outcomes: The Taiwan Stroke Registry

Taiwan Stroke Registry Investigators, 2017 Jun 22, In : Journal of the American Heart Association. 6, 6

Research output: Contribution to journalArticle

3 Citations (Scopus)
8 Citations (Scopus)

Midbrain hemorrhage presenting with trochlear nerve palsy

Chen, C-H., Hwang, W. J., Tsai, T. & Lai, M. L., 2000 Feb 1, In : Chinese Medical Journal (Taipei). 63, 2, p. 138-143 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
16 Citations (Scopus)

Nontraumatic intracerebral hemorrhage in young adults: Analysis of 214 cases

Chen, C. H. & Lai, M. L., 1999 Jan 1, In : Acta Neurologica Taiwanica. 8, 2, p. 96-101 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

One-Year Risk of Recurrent Stroke and Death Associated with Vertebrobasilar Artery Stenosis and Occlusion in a Cohort of 10,515 Patients

Qureshi, A. I., Qureshi, M. H., Lien, L. M., Lee, J. T., Jeng, J. S., Hu, C. J., Lai, T. C., Liu, C. H., Chen, C. H., Chen, P. L., Chen, T. S., Li, J. Y., Lin, C. L. & Hsu, C. Y., 2019 Apr 1, In : Cerebrovascular Diseases. 47, 1-2, p. 40-47 8 p.

Research output: Contribution to journalArticle

Optimal dose for stroke thrombolysis in Asians: Low dose may have similar safety and efficacy as standard dose

Chen, C. H., Hsieh, C. Y., Lai, T. B., Chuang, M. T., Chen, W. L. & Sun, M. C., 2012 Jul 1, In : Journal of Thrombosis and Haemostasis. 10, 7, p. 1270-1275 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Osmotherapy with hypertonic saline attenuates water content in brain and extracerebral organs

Toung, T. J. K., Chen, C. H., Lin, C. & Bhardwaj, A., 2007 Feb 1, In : Critical care medicine. 35, 2, p. 526-531 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)