• 1126 Citations
  • 17 h-Index
20042020

Research output per year

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Research Output

  • 1126 Citations
  • 17 h-Index
  • 99 Article
  • 2 Review article
2020

Early moderate intensity aerobic exercise intervention prevents doxorubicin-caused cardiac dysfunction through inhibition of cardiac fibrosis and inflammation

Yang, H. L., Hsieh, P. L., Hung, C. H., Cheng, H. C., Chou, W. C., Chu, P. M., Chang, Y. C. & Tsai, K. L., 2020 May, In : Cancers. 12, 5, 1102.

Research output: Contribution to journalArticle

Open Access
Open Access

Pulse Oximetry Monitor Feasible for Early Screening of Obstructive Sleep Apnea (OSA)

Lin, H. C., Su, C. L., Ong, J. H., Tsai, K. L., Chen, Y. W., Lin, C. Y., Chiang, L. L. & Hung, C. H., 2020 Feb 1, In : Journal of Medical and Biological Engineering. 40, 1, p. 62-70 9 p.

Research output: Contribution to journalArticle

The effects of threshold inspiratory muscle training in patients with obstructive sleep apnea: a randomized experimental study

Lin, H. C., Chiang, L. L., Ong, J. H., Tsai, K. L., Hung, C. H. & Lin, C. Y., 2020 Mar 1, In : Sleep and Breathing. 24, 1, p. 201-209 9 p.

Research output: Contribution to journalArticle

The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease

Chen, T. Y., Li, X., Hung, C. H., Bahudhanapati, H., Tan, J., Kass, D. J. & Zhang, Y., 2020 Jan 1, (Accepted/In press) In : Molecular Genetics and Genomic Medicine.

Research output: Contribution to journalReview article

Open Access
2019

Chlorpheniramine produces cutaneous analgesia in rats

Chiu, C. C., Liu, K. S., Chen, Y. W., Hung, C. H. & Wang, J. J., 2019 Jan 1, (Accepted/In press) In : Pharmacological Reports.

Research output: Contribution to journalArticle

Dopamine enhancement of dextrorphan-induced skin antinociception in response to needle pinpricks in rats

Li, Y. Y., Chiu, C. C., Wang, J. J., Chen, Y. W. & Hung, C. H., 2019 Aug, In : Pharmacological Reports. 71, 4, p. 732-737 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Fucoxanthin Protects against oxLDL-Induced Endothelial Damage via Activating the AMPK-Akt-CREB-PGC1α Pathway

Ou, H. C., Chou, W. C., Chu, P. M., Hsieh, P. L., Hung, C. H. & Tsai, K. L., 2019 May, In : Molecular Nutrition and Food Research. 63, 10, 1801353.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Galectin-3 aggravates ox-LDL-induced endothelial dysfunction through LOX-1 mediated signaling pathway

Ou, H. C., Chou, W. C., Hung, C. H., Chu, P. M., Hsieh, P. L., Chan, S. H. & Tsai, K. L., 2019 Jul, In : Environmental Toxicology. 34, 7, p. 825-835 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1 Citation (Scopus)

Multimodal exercise ameliorates exercise responses and body composition in head and neck cancer patients receiving chemotherapy

Yen, C. J., Hung, C. H., Kao, C. L., Tsai, W. M., Chan, S. H., Cheng, H. C., Jheng, W. T., Lu, Y. J. & Tsai, K. L., 2019 Dec 1, In : Supportive Care in Cancer. 27, 12, p. 4687-4695 9 p.

Research output: Contribution to journalArticle

Phentolamine Reverses Epinephrine-Enhanced Skin Antinociception of Dibucaine in Rats

Chou, A. K., Chiu, C. C., Chen, Y. W., Wang, J. J. & Hung, C. H., 2019 Jun 1, In : Anesthesia and analgesia. 128, 6, p. 1336-1343 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
Open Access
1 Citation (Scopus)

Serotonin enhances oxybuprocaine- and proxymetacaine-induced cutaneous analgesia in rats

Chou, A. K., Chiu, C. C., Wang, J. J., Chen, Y. W. & Hung, C-H., 2019 Mar 5, In : European Journal of Pharmacology. 846, p. 73-78 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Subcutaneous brompheniramine for cutaneous analgesia in rats

Chiu, C. C., Chen, J. Y., Chen, Y. W., Wang, J. J. & Hung, C. H., 2019 Oct 5, In : European Journal of Pharmacology. 860, 172544.

Research output: Contribution to journalArticle

Ultrasound therapy reduces persistent post-thoracotomy tactile allodynia and spinal substance P expression in rats

Lin, H. T., Chiu, C. C., Liu, C. C., Chen, Y. W., Wang, J. J. & Hung, C. H., 2019 May 1, In : Regional anesthesia and pain medicine. 44, 5, p. 604-608 5 p.

Research output: Contribution to journalArticle

2018

Adding dopamine to proxymetacaine or oxybuprocaine solutions potentiates and prolongs the cutaneous antinociception in rats

Chen, Y. W., Chiu, C. C., Lin, H. T., Wang, J. J. & Hung, C. H., 2018 May 1, In : Anesthesia and analgesia. 126, 5, p. 1721-1728 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells

Tsai, K. L., Hung, C. H., Chan, S. H., Hsieh, P. L., Ou, H. C., Cheng, Y. H. & Chu, P. M., 2018 Jun, In : Molecular Nutrition and Food Research. 62, 11, 1700928.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling

Chan, S. H., Hung, C. H., Shih, J. Y., Chu, P. M., Cheng, Y. H., Lin, H. C., Hsieh, P. L. & Tsai, K. L., 2018 Apr, In : Redox Biology. 14, p. 116-125 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis

Ma, C. H., Chiu, Y. C., Wu, C. H., Jou, I. M., Tu, Y. K., Hung, C. H., Hsieh, P. L. & Tsai, K. L., 2018 May, In : Redox Biology. 15, p. 504-512 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Intrathecal pramoxine causes long-lasting spinal sensory and motor block in rats

Chou, A. K., Chiu, C. C., Han, M. M., Chen, Y. W., Wang, J. J. & Hung, C. H., 2018 Apr, In : Journal of Pharmacy and Pharmacology. 70, 4, p. 543-549 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Local Application of Ultrasound Attenuates Neuropathic Allodynia and Proinflammatory Cytokines in Rats after Thoracotomy

Hung, C. H., Chiu, C. C., Liu, C. C. & Chen, Y. W., 2018 Feb 1, In : Regional anesthesia and pain medicine. 43, 2, p. 193-199 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1 Citation (Scopus)

PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes

Ma, C. H., Wu, C. H., Jou, I. M., Tu, Y. K., Hung, C. H., Hsieh, P. L. & Tsai, K. L., 2018 Apr, In : Redox Biology. 14, p. 72-81 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Skin nociceptive block with pramoxine delivery by subcutaneous injection in rats

Chou, A. K., Chiu, C. C., Chen, Y. W., Wang, J. J. & Hung, C. H., 2018 Dec, In : Pharmacological Reports. 70, 6, p. 1180-1184 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Spinal sensory and motor blockade by intrathecal doxylamine and triprolidine in rats

Tzeng, J. I., Chiu, C. C., Wang, J. J., Hung, C. H. & Chen, Y. W., 2018 Dec, In : Journal of Pharmacy and Pharmacology. 70, 12, p. 1654-1661 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Subcutaneous infiltration of doxylamine on cutaneous analgesia in rats

Hung, C. H., Shieh, J. P., Chiu, C. C., Wang, J. J. & Chen, Y. W., 2018 Jun, In : Pharmacological Reports. 70, 3, p. 565-569 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

2-Adamantanamine produces prolonged spinal block in rats

Chen, Y. W., Chen, C. M., Liu, K. S., Wang, J. J. & Hung, C. H., 2017 Jul 13, In : Neuroscience Letters. 653, p. 168-172 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Chicoric acid is a potent anti-atherosclerotic ingredient by antioxidant action and anti-inflammation capacity

Tsai, K. L., Kao, C. L., Hung, C. H., Cheng, Y. H., Lin, H. C. & Chu, P. M., 2017 Jan 1, In : Oncotarget. 8, 18, p. 29600-29612 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Exercise combined with ultrasound attenuates neuropathic pain in rats associated with downregulation of IL-6 and TNF-α, but with upregulation of IL-10

Huang, P. C., Tsai, K. L., Chen, Y. W., Lin, H. T. & Hung, C. H., 2017 Jun 1, In : Anesthesia and analgesia. 124, 6, p. 2038-2044 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
4 Citations (Scopus)

Isobolographic analysis of the cutaneous antinociceptive interaction between bupivacaine co-injected with serotonin in rats

Tzeng, J. I., Chiu, C. C., Wang, J. J., Chen, Y. W. & Hung, C. H., 2017 Oct, In : Pharmacological Reports. 69, 5, p. 846-850 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Mexiletine co-injected with clonidine increases the quality and duration of cutaneous analgesia in response to skin pinpricks in the rat

Han, M. M., Chiu, C. C., Wang, J. J., Chen, Y. W. & Hung, C-H., 2017 Jul 27, In : Neuroscience Letters. 654, p. 23-27 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Naloxone prolongs cutaneous nociceptive block by lidocaine in rats

Chen, Y. W., Shieh, J. P., Liu, K. S., Wang, J. J. & Hung, C. H., 2017 Dec, In : Fundamental and Clinical Pharmacology. 31, 6, p. 636-642 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

SIRT1 inhibition causes oxidative stress and inflammation in patients with coronary artery disease

Chan, S. H., Hung, C. H., Shih, J. Y., Chu, P. M., Cheng, Y. H., Lin, H. C. & Tsai, K. L., 2017 Oct, In : Redox Biology. 13, p. 301-309 9 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Synergistic effects of serotonin or dopamine combined with lidocaine at producing nociceptive block in rats

Hung, C. H., Chiu, C. C., Liu, K. S., Chen, Y. W. & Wang, J. J., 2017 Jan 1, In : Regional anesthesia and pain medicine. 42, 3, p. 351-356 6 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2016

Baicalein is an available anti-atherosclerotic compound through modulation of nitric oxide-related mechanism under oxLDL exposure

Chan, S. H., Hung, C. H., Shih, J. Y., Chu, P. M., Cheng, Y. H., Tsai, Y. J., Lin, H. C. & Tsai, K. L., 2016 Jan 1, In : Oncotarget. 7, 28, p. 42881-42891 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha

Tsai, K. L., Hung, C. H., Chan, S. H., Shih, J. Y., Cheng, Y. H., Tsai, Y. J., Lin, H. C. & Chu, P. M., 2016 Jan 1, In : Oncotarget. 7, 45, p. 72458-72468 11 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Clonidine as an adjuvant for propranolol enhances its effect on infiltrative cutaneous analgesia in rats

Hung, C. H., Chiu, C. C., Liu, K. S., Wang, J. J. & Chen, Y. W., 2016 Mar 11, In : Neuroscience Letters. 616, p. 70-74 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Cutaneous synergistic analgesia of bupivacaine in combination with dopamine in rats

Tzeng, J. I., Wang, J. N., Wang, J. J., Chen, Y. W. & Hung, C. H., 2016 May 4, In : Neuroscience Letters. 620, p. 88-92 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Ifenprodil for prolonged spinal blockades of motor function and nociception in rats

Chen, Y. W., Chiu, C. C., Wang, J. N., Hung, C. H. & Wang, J. J., 2016 Apr 1, In : Pharmacological Reports. 68, 2, p. 357-362 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Intrathecal amantadine for prolonged spinal blockade of sensory and motor functions in rats

Tzeng, J. I., Kan, C. D., Wang, J. N., Wang, J. J., Lin, H. T. & Hung, C. H., 2016 Aug 1, In : Fundamental and Clinical Pharmacology. 30, 4, p. 357-363 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Intrathecal rimantadine induces motor, proprioceptive, and nociceptive blockades in rats

Tzeng, J. I., Wang, J. N., Wang, J. J., Chen, Y. W. & Hung, C. H., 2016 Apr 8, In : Neuroscience Letters. 618, p. 94-98 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling

Hung, C. H., Chan, S. H., Chu, P. M., Lin, H. C. & Tsai, K. L., 2016 Jan 1, In : Oncotarget. 7, 10, p. 10773-10787 15 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Oleic acid activates MMPs up-regulation through SIRT1/PPAR-γ inhibition: A probable linkage between obesity and coronary arterial disease

Chan, S-H., Chu, P. M., Kao, C. L., Cheng, Y. H., Hung, C-H. & Tsai, K-L., 2016 Oct 1, In : Journal of biochemistry. 160, 4, p. 217-225 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The addition of epinephrine to proxymetacaine or oxybuprocaine solution increases the depth and duration of cutaneous analgesia in rats

Chen, Y. W., Chiu, C. C., Kan, C. D., Wang, J. J. & Hung, C. H., 2016 Aug 23, In : Regional anesthesia and pain medicine. 41, 5, p. 601-606 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The potential role of epigenetic modulations in BPPV maneuver exercises

Tsai, K. L., Wang, C. T., Kuo, C. H., Cheng, Y. Y., Ma, H. I., Hung, C. H., Tsai, Y. J. & Kao, C. L., 2016 Jan 1, In : Oncotarget. 7, 24, p. 35522-35534 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Therapeutic ultrasound and treadmill training suppress peripheral nerve injury–induced pain in rats

Hung, C. H., Huang, P. C., Tzeng, J. I., Wang, J. J. & Chen, Y. W., 2016 Oct, In : Physical therapy. 96, 10, p. 1545-1553 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

Chlorpheniramine produces spinal motor, proprioceptive and nociceptive blockades in rats

Tzeng, J. I., Lin, H. T., Chen, Y. W., Hung, C. H. & Wang, J. J., 2015 Apr 5, In : European Journal of Pharmacology. 752, p. 55-60 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)