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Research Output 2001 2019

  • 717 Citations
  • 16 h-Index
  • 37 Article
  • 3 Patent
  • 1 Book
  • 1 Comment/debate
2019
2 Citations (Scopus)

Enterovirus A71 containing codon-deoptimized VP1 and high-fidelity polymerase as next-generation vaccine candidate

Tsai, Y. H., Huang, S. W., Hsieh, W. S., Cheng, C. K., Chang, C-F., Wang, Y. F. & Wang, J-R., 2019 Jan 1, In : Journal of Virology. 93, 13, e02308-18.

Research output: Contribution to journalArticle

Enterovirus
codons
Codon
Vaccines
vaccines
1 Citation (Scopus)

Glycoproteomic identification of novel plasma biomarkers for oral cancer

Chang, S. C., Lin, W. L., Chang, Y-F., Lee, C-T., Wu, J-S., Hsu, P. H. & Chang, C-F., 2019 Apr 1, In : Journal of Food and Drug Analysis. 27, 2, p. 483-493 11 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
biomarkers
Biomarkers
glycoproteins
Glycoproteins
1 Citation (Scopus)

Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer

Chuang, P. K., Hsiao, M., Hsu, T. L., Chang, C-F., Wu, C. Y., Chen, B. R., Huang, H. W., Liao, K. S., Chen, C. C., Chen, C. L., Yang, S. M., Kuo, C. W., Chen, P., Chiu, P. T., Chen, I. J., Lai, J. S., Yu, C. D. T. & Wong, C. H., 2019 Feb 26, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3518-3523 6 p.

Research output: Contribution to journalArticle

Galactosyltransferases
Glycosphingolipids
Receptor-Interacting Protein Serine-Threonine Kinases
Protein Kinases
Breast Neoplasms

Targeted delivery of curcumin rescues endoplasmic reticulum-retained mutant Nox2 protein and avoids leukocyte apoptosis

Yen, C. L., Liao, Y. C., Chen, R. F., Huang, Y. F., Chung, W. C., Lo, P. C., Chang, C. F., Wu, P. C., Shieh, D. B., Jiang, S. T. & Shieh, C. C., 2019 Jun 15, In : Journal of Immunology. 202, 12, p. 3394-3403 10 p.

Research output: Contribution to journalArticle

Curcumin
Mutant Proteins
Endoplasmic Reticulum
Leukocytes
Apoptosis
2018

Detection of adulterated drugs in traditional Chinese medicine and dietary supplements using hydrogen as a carrier gas

Lin, Y. P., Lee, Y. L., Hung, C. Y., Chang, C-F. & Chen, Y., 2018 Oct 1, In : PloS one. 13, 10, e0205371.

Research output: Contribution to journalArticle

Dietary supplements
Chinese Traditional Medicine
Dietary Supplements
hydrogen
Medicine

Glycan-binding preferences and genetic evolution of human seasonal influenza A (H3N2) viruses during 1999-2007 in Taiwan

Wang, Y. F., Chang, C. F., Tsai, H. P., Chi, C. Y., Su, I. J. & Wang, J. R., 2018 May, In : PloS one. 13, 5, e0196727.

Research output: Contribution to journalArticle

H3N2 Subtype Influenza A Virus
Molecular Evolution
Influenza A virus
Taiwan
Viruses
3 Citations (Scopus)

Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells

Chen, H. P., Lee, Y. K., Huang, S. Y., Shi, P. C., Hsu, P. C. & Chang, C. F., 2018 Jan 1, In : Oncotarget. 9, 17, p. 13167-13180 14 p.

Research output: Contribution to journalArticle

Drug Resistance
Colonic Neoplasms
P-Glycoprotein
Catenins
irinotecan

Toll-like receptor 3 is involved in detection of enterovirus a71 infection and targeted by viral 2a protease

Chen, K. R., Yu, C. K., Kung, S. H., Chen, S. H., Chang, C. F., Ho, T. C., Lee, Y. P., Chang, H. C., Huang, L. Y., Lo, S. Y., Chang, J. C. & Ling, P., 2018 Dec 1, In : Viruses. 10, 12, 689.

Research output: Contribution to journalArticle

Toll-Like Receptor 3
Enterovirus Infections
Peptide Hydrolases
Antiviral Agents
Enterovirus
2017
6 Citations (Scopus)

Monocytic thrombomodulin promotes cell adhesion through interacting with its ligand, Lewis y

Lin, W. L., Chen, C. C., Shi, G. Y., Ma, C. Y., Chang, C-F. & Wu, H-L., 2017 Apr 1, In : Immunology and Cell Biology. 95, 4, p. 372-379 8 p.

Research output: Contribution to journalArticle

Thrombomodulin
Cell Adhesion
Ligands
Leukocytes
Endothelium
5 Citations (Scopus)

Serum N-glycome characterization and anti-carbohydrate antibody profiling in oral squamous cell carcinoma patients

Guu, S. Y., Lin, T. H., Chang, S. C., Wang, R. J., Hung, L. Y., Fang, P. J., Tang, W. C., Yu, P. & Chang, C. F., 2017 Jun, In : PloS one. 12, 6, e0178927.

Research output: Contribution to journalArticle

squamous cell carcinoma
Polysaccharides
Anti-Idiotypic Antibodies
Squamous Cell Carcinoma
mouth
Enterovirus
Interleukin-6
Enterovirus Infections
Encephalitis
Viruses
2016
25 Citations (Scopus)

Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells

Cheung, S. K. C., Chuang, P. K., Huang, H. W., Hwang-Verslues, W. W., Cho, C. H. H., Yang, W. B., Shen, C. N., Hsiao, M., Hsu, T. L., Chang, C-F. & Wong, C. H., 2016 Jan 26, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 4, p. 960-965 6 p.

Research output: Contribution to journalArticle

CD15 Antigens
Galactosyltransferases
Neoplastic Stem Cells
Breast Neoplasms
Neoplasms
2015
38 Citations (Scopus)

Cell surface nucleolin facilitates enterovirus 71 binding and infection

Su, P. Y., Wang, Y. F., Huang, S. W., Lo, Y-C., Wang, Y. H., Wu, S-R., Shieh, D-B., Chen, S., Wang, J-R., Lai, M-D. & Chang, C-F., 2015 Jan 1, In : Journal of Virology. 89, 8, p. 4527-4538 12 p.

Research output: Contribution to journalArticle

Enterovirus
Infection
infection
cells
Enterovirus Infections
3 Citations (Scopus)

Derivation of cinnamon blocks leukocyte attachment by interacting with sialosides

Lin, W. L., Guu, S. Y., Tsai, C. C., Prakash, E., Viswaraman, M., Chen, H. B. & Chang, C-F., 2015 Jun 15, In : PloS one. 10, 6, e0130389.

Research output: Contribution to journalArticle

Cinnamomum zeylanicum
cinnamon
leukocytes
Leukocytes
Sialic Acids

Dr. Frederick H. Kasten 1927 -2014

Chang, C-F., 2015 Feb 1, In : Biotechnic & histochemistry : official publication of the Biological Stain Commission. 90, 2, p. 152-156 5 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
Cell Biology
9 Citations (Scopus)

Lewis y promotes migration of oral cancer cells by glycosylation of epidermal growth factor receptore0120162

Lin, W. L., Lin, Y. S., Shi, G. Y., Chang, C-F. & Wu, H-L., 2015 Mar 23, In : PloS one. 10, 3, e0120162.

Research output: Contribution to journalArticle

Glycosylation
Mouth Neoplasms
epidermal growth factor
glycosylation
Epidermal Growth Factor Receptor
2014
26 Citations (Scopus)

Leukocyte cell-derived chemotaxin 2 antagonizes MET receptor activation to suppress hepatocellular carcinoma vascular invasion by protein tyrosine phosphatase 1B recruitment

Chen, C. K., Yang, C. Y., Hua, K. T., Ho, M. C., Johansson, G., Jeng, Y. M., Chen, C. N., Chen, M. W., Lee, W. J., Su, J. L., Lai, T. C., Chou, C. C., Ho, B. C., Chang, C-F., Lee, P. H., Chang, K. J., Hsiao, M., Lin, M. T. & Kuo, M. L., 2014 Jan 1, In : Hepatology. 59, 3, p. 974-985 12 p.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Chemotactic Factors
Blood Vessels
Hepatocellular Carcinoma
Leukocytes

鑑定液體性質之裝置與方法

Chang, H-C. & Chang, C-F., 2014 Dec 16, Patent No. I 546538

Research output: Patent

2013
12 Citations (Scopus)

Anterior gradient 2: A novel sensitive tumor marker for metastatic oral cancer

Chen, Y. T., Ho, C-L., Chen, P. K., Chen, Y-L. & Chang, C-F., 2013 Oct 10, In : Cancer Letters. 339, 2, p. 270-278 9 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Tumor Biomarkers
Biomarkers
Neoplasm Metastasis
Gene Expression Profiling
24 Citations (Scopus)
epirubicin
Galectin 3
Glycogen Synthase Kinase 3
Catenins
Epirubicin
16 Citations (Scopus)

Identification of novel tumor markers for oral squamous cell carcinoma using glycoproteomic analysis

Chen, Y. T., Chong, Y. M., Cheng, C. W., Ho, C-L., Tsai, H-W., Kasten, F. H., Chen, Y. L. & Chang, C-F., 2013 Jan 1, In : Clinica Chimica Acta. 420, p. 45-53 9 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Polysaccharides
Squamous Cell Carcinoma
Keratinocytes
Fucosyltransferases
14 Citations (Scopus)
Thrombomodulin
Lectins
Blood Vessels
Leukocytes
Endothelial Cells
10 Citations (Scopus)

Thrombomodulin functions as a plasminogen receptor to modulate angiogenesis

Chen, P. K., Chang, B. I., Kuo, C. H., Chen, P. S., Cho, C. F., Chang, C. F., Shi, G. Y. & Wu, H. L., 2013 Nov 1, In : FASEB Journal. 27, 11, p. 4520-4531 12 p.

Research output: Contribution to journalArticle

Thrombomodulin
Plasminogen
Proteolysis
Urokinase Plasminogen Activator Receptors
Urokinase-Type Plasminogen Activator
29 Citations (Scopus)

Cell surface sialylation affects binding of enterovirus 71 to rhabdomyosarcoma and neuroblastoma cells

Su, P. Y., Liu, Y. T., Chang, H. Y., Huang, S. W., Wang, Y. F., Yu, C. K., Wang, J. R. & Chang, C. F., 2012 Aug 3, In : BMC microbiology. 12, 162.

Research output: Contribution to journalArticle

Rhabdomyosarcoma
Enterovirus
Neuroblastoma
Enterovirus Infections
Sialic Acids
21 Citations (Scopus)

Characterization of glycan binding specificities of influenza B viruses with correlation with hemagglutinin genotypes and clinical features

Wang, Y. F., Chang, C-F., Chi, C. Y., Wang, H. C., Wang, J-R. & Su, I. J., 2012 Apr 1, In : Journal of Medical Virology. 84, 4, p. 679-685 7 p.

Research output: Contribution to journalArticle

Influenza B virus
Hemagglutinins
Polysaccharides
Genotype
Human Influenza

Receptor binding surveillance of influenza clinical isolates

Wang, Y. F., Lao, W. I., Kuo, Y. D., Guu, S. Y., Wang, H. C., Lin, C. H., Wang, J. R., Su, I. J. & Chang, C. F., 2012 Jun 1, In : Future Virology. 7, 6, p. 621-633 13 p.

Research output: Contribution to journalArticle

Human Influenza
Polysaccharides
Influenza B virus
Pandemics
Viral Tropism
30 Citations (Scopus)

The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis Y antigen

Kuo, C. H., Chen, P. K., Chang, B. I., Sung, M. C., Shi, C. S., Lee, J. S., Chang, C. F., Shi, G. Y. & Wu, H. L., 2012 Feb 2, In : Blood. 119, 5, p. 1302-1313 12 p.

Research output: Contribution to journalArticle

Thrombomodulin
Lectins
Endothelial cells
Chemotaxis
Epidermal Growth Factor Receptor
2011
6 Citations (Scopus)

Functional characterisation of a complex mutation in the α(1,4)galactosyltransferase gene in Taiwanese individuals with p phenotype

Wang, Y-C., Chang, C-F., Lin, H. C., Lin, K. S., Lin, K. T., Hung, C. M. & Lin, T. M., 2011 Apr 1, In : Transfusion Medicine. 21, 2, p. 84-89 6 p.

Research output: Contribution to journalArticle

Galactosyltransferases
Phenotype
Mutation
Genes
Enzymes
25 Citations (Scopus)

Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli

Cheng, Y. L., Huang, W. C., Chen, C. L., Tsai, C. C., Wang, C. Y., Chiu, W-H., Chen, Y-L., Lin, Y-S., Chang, C-F. & Lin, C. F., 2011 Aug 26, In : Biochemical and Biophysical Research Communications. 412, 2, p. 334-340 7 p.

Research output: Contribution to journalArticle

Galectin 3
Cell Survival
Leukemia
Cells
Glycogen Synthase Kinase 3
8 Citations (Scopus)

Profiling of influenza viruses by high-throughput carbohydrate membrane array

Lao, W. I., Wang, Y. F., Kuo, Y. D., Lin, C. H., Chang, T. C., Su, I. J., Wang, J-R. & Chang, C-F., 2011 Mar 1, In : Future Medicinal Chemistry. 3, 3, p. 283-296 14 p.

Research output: Contribution to journalArticle

Orthomyxoviridae
Carbohydrates
Membranes
Lectins
Polysaccharides
27 Citations (Scopus)

Rapid characterization of sugar-binding specificity by in-solution proximity binding with photosensitizers

Chang, C-F., Pan, J. F., Lin, C. N., Wu, I. L., Wong, C. H. & Lin, C. H., 2011 Jul 1, In : Glycobiology. 21, 7, p. 895-902 8 p.

Research output: Contribution to journalArticle

Photosensitizing Agents
Sugars
Carbohydrates
Lectins
Polysaccharides
2008
12 Citations (Scopus)

C-terminal repeats of Clostridium difficile toxin a induce production of chemokine and adhesion molecules in endothelial cells and promote migration of leukocytes

Yeh, C. Y., Lin, C. N., Chang, C-F., Lin, C. H., Lien, H. T., Chen, J. Y. & Chia, J. S., 2008 Mar 1, In : Infection and Immunity. 76, 3, p. 1170-1178 9 p.

Research output: Contribution to journalArticle

Clostridium difficile
Terminal Repeat Sequences
Chemokines
Cell Movement
Leukocytes
116 Citations (Scopus)

Lectin-like domain of thrombomodulin binds to its specific ligand Lewis y antigen and neutralizes lipopolysaccharide-induced inflammatory response

Shi, C. S., Shi, G. Y., Hsiao, S. M., Kao, Y. C., Kuo, K. L., Chih-Yuan, M., Kuo, C. H., Chang, B. I., Chang, C. F., Lin, C. H., Wong, C. H. & Wu, H. L., 2008 Nov 1, In : Blood. 112, 9, p. 3661-3670 10 p.

Research output: Contribution to journalArticle

Thrombomodulin
Lectins
Lipopolysaccharides
Ligands
Antigens
2006
24 Citations (Scopus)

Discovery of different types of inhibition between the human and Thermotoga maritima α-fucosidases by fuconojirimycin-based derivatives

Ho, C. W., Lin, Y. N., Chang, C-F., Li, S. T., Wu, Y. T., Wu, C. Y., Chang, C. F., Liu, S. W., Li, Y. K. & Lin, C. H., 2006 May 9, In : Biochemistry. 45, 18, p. 5695-5702 8 p.

Research output: Contribution to journalArticle

Thermotoga maritima
alpha-L-Fucosidase
Derivatives
Substitution reactions
Enzymes
2004
60 Citations (Scopus)

Discovery of picomolar slow tight-binding inhibitors of α-fucosidase

Chang, C-F., Ho, C. W., Wu, C. Y., Chao, T. A., Wong, C. H. & Lin, C. H., 2004 Sep 1, In : Chemistry and Biology. 11, 9, p. 1301-1306 6 p.

Research output: Contribution to journalArticle

alpha-L-Fucosidase
Enzyme Inhibitors
Glycoside Hydrolases
Corynebacterium
Medical problems

Erratum: Discovery of picomolar slow tight-binding inhibitors of α-fucosidase (Chemistry and Biology (2004) (1301-1306))

Chang, C-F., Ho, C. W., Wu, C. Y., Chao, T. A., Wong, C. H. & Lin, C. H., 2004 Nov 1, In : Chemistry and Biology. 11, 11, 1 p.

Research output: Contribution to journalComment/debate

alpha-L-Fucosidase
2003
109 Citations (Scopus)

Rapid diversity-oriented synthesis in microtiter plates for in situ screening: Discovery of potent and selective α-fucosidase inhibitors

Wu, C. Y., Chang, C-F., Chen, J. S. Y., Wong, C. H. & Lin, C. H., 2003 Oct 6, In : Angewandte Chemie - International Edition. 42, 38, p. 4661-4664 4 p.

Research output: Contribution to journalArticle

alpha-L-Fucosidase
Carboxylic Acids
Carboxylic acids
Amides
Assays
2002
27 Citations (Scopus)

Inter- and intramolecular alcohol additions to exo-glycals

Chang, C-F., Yang, W. B., Chang, C. C. & Lin, C. H., 2002 Sep 9, In : Tetrahedron Letters. 43, 37, p. 6515-6519 5 p.

Research output: Contribution to journalArticle

Sugars
Alcohols
Acids
2001
28 Citations (Scopus)

Expeditious synthesis of C-glycosyl conjugated dienes and aldehydes from sugar lactones

Yang, W. B., Chang, C-F., Wang, S. H., Teo, C. F. & Lin, C. H., 2001 Jul 9, In : Tetrahedron Letters. 42, 28, p. 4657-4660 4 p.

Research output: Contribution to journalArticle

Lactones
Dehydration
Aldehydes
Sugars
Chlorides
1800

核仁蛋白抑制劑的醫藥用途

Chang, C-F., 1800, Patent No. I517860

Research output: Patent