Projects per year
Personal profile
Education
- 2007 PhD, Department of Molecular Medicine, University of Auckland
Experience
- 2011~2016 Assistant Professor, Department of Pharmacology, National Cheng Kung University
- 2016~present Associate Professor, Department of Pharmacology, National Cheng Kung University
Research Interests
- Anti-cancer nanodrug development
- Cancer drug resistance mechanism
- Cancer cell autophagy
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Projects
- 9 Finished
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以存活素為中心探討過度活化自噬作用誘導DNA損傷與基因體不穩定的可能性
Cheung, C. H. A. (PI)
21-08-01 → 22-07-31
Project: Research project
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探討存活素、巨自噬作用、粒線體自噬作用、染色質自噬作用之間未知的交互作用與調控機制
Cheung, C. H. A. (PI)
20-08-01 → 21-07-31
Project: Research project
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探討細胞凋亡蛋白「存活素」之未知功能 - 細胞自噬及自噬作用相關之DNA穩定調控
Cheung, C. H. A. (PI)
19-08-01 → 20-07-31
Project: Research project
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NUPR1 contributes to endocrine therapy resistance by modulating BIRC5 expression and inducing luminal B-ERBB2+ subtype-like characteristics in estrogen receptor-positive breast cancer cells
Lee, C. H., Lin, Y. C., Chang, Y. C., Chen, P. C., Lin, K. H., Yeh, T. M., Leung, E. Y., Lin, I. L., Chen, S. H. & Cheung, C. H. A., 2025, In: Journal of Cancer. 16, 5, p. 1694-1708 15 p.Research output: Contribution to journal › Article › peer-review
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Benign polymorphisms in the BRCA genes with linkage disequilibrium is associated with cancer characteristics
Lee, K. T., Chen, D. P., Loh, Z. J., Chung, W. P., Wang, C. Y., Chen, P. S., Cheung, C. H. A., Chang, C. P. & Hsu, H. P., 2024 Dec, In: Cancer Science. 115, 12, p. 3973-3985 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The SMAC mimetic GDC-0152 is a direct ABCB1-ATPase activity modulator and BIRC5 expression suppressor in cancer cells
Lin, I. L., Lin, Y. T., Chang, Y. C., Kondapuram, S. K., Lin, K. H., Chen, P. C., Kuo, C. Y., Coumar, M. S. & Cheung, C. H. A., 2024 Apr, In: Toxicology and Applied Pharmacology. 485, 116888.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Hypoxia in drug resistance and radioresistance
Chang, K. Y., Lin, I. L. & Cheung, C. H. A., 2023 Apr 13, Hypoxia in Cancer: Significance and Impact on Cancer Therapy. Springer, p. 433-447 15 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Development of a cancer cells self-activating and miR-125a-5p expressing poly-pharmacological nanodrug for cancer treatment
Chang, Y. C., Shieh, M. C., Chang, Y. H., Huang, W. L., Su, W. C., Cheng, F. Y. & Cheung, C. H. A., 2022 Aug, In: International journal of molecular medicine. 50, 2, 102.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus)