Chun-Hsien Chu

Personal profile

Education

2008 PhD, Institute of Biochemistry & Biotechnology, Chung Shan Medical University, Taichung, Taiwan

Research Interests

microglia biology
Neuroinflammation
Neuroscience

Experience

2010/03~2011/03 Special volunteer, National Institutes of Health/National Institute of Environmental Health Sciences (NIH/NIEHS), RTP, NC, USA
2009/09~2011/03 Postdoctoral Fellow, Institute of Behavioral Medicine, National Cheng Kung University, Tainan, Taiwan
2011/04~2015/02 Visiting Fellow, National Institutes of Health/National Institute of Environmental Health Sciences (NIH/NIEHS), RTP, NC, USA
2015/03~2016/01 Postdoctoral Fellow, Institute of Molecular Medicine, National Cheng Kung University, Tainan, Taiwan
2016/02~ Project Assistant Professor, Institute of Molecular Medicine, National Cheng Kung University, Tainan, Taiwan

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Projects 2016 2020

1 Active
2 Finished

腦內TIAM2S在自閉症形成所扮演病理生理的角色和其作用機制

Chu, C.

19-08-01 → 20-07-31

Project: Research project

促癌蛋白TIAM2S調節腦中小膠質細胞活化、血清素平衡以及神經退化之分子機制:人類TIAM2S基因轉殖鼠作為全新老化相關神經退行性疾病動物模型的探索

Chu, C.

17-11-01 → 18-07-31

Project: Research project

促癌蛋白TIAM2S調節腦中小膠質細胞活化、血清素平衡以及神經退化之分子機制:人類TIAM2S基因轉殖鼠作為全新老化相關神經退行性疾病動物模型的探索

Chu, C.

16-11-01 → 17-10-31

Project: Research project

Research Output 2004 2019

1342 Citations
22 h-Index
62 Article
3 Comment/debate
1 Letter
1 Review article

Correlation between interleukin-6 levels and methadone maintenance therapy outcomes

Lu, R. B., Wang, T. Y., Lee, S. Y., Chen, S. L., Chang, Y. H., See Chen, P., Lin, S. H., Chu, C. H., Huang, S. Y., Tzeng, N. S., Lee, I. H., Chin Chen, K., Kuang Yang, Y., Chen, P., Chen, S. H. & Hong, J. S., 2019 Nov 1, In : Drug and Alcohol Dependence. 204, 107516.

Research output: Contribution to journal › Article

Methadone

Interleukin-6

Opioid Analgesics

Brain-Derived Neurotrophic Factor

Morphine

Immunoregulatory effects of very low density lipoprotein from healthy individuals and metabolic syndrome patients on glial cells

Li, C. L., Chu, C. H., Lee, H. C., Chou, M. C., Liu, C. K., Chen, C. H., Ke, L. Y. & Chen, S. L., 2019 Sep, In : Immunobiology. 224, 5, p. 632-637 6 p.

Research output: Contribution to journal › Article

VLDL Lipoproteins

Microglia

Neuroglia

Astrocytes

Dinoprostone

1 Citation (Scopus)

Correlation of cytokines, BDNF levels, and memory function in patients with opioid use disorder undergoing methadone maintenance treatment

Wang, T-Y., Lee, S. Y., Chang, Y. H., Chen, S. L., Chen, P-S., Chu, C-H., Huang, S. Y., Tzeng, N. S., Lee, I-H., Chen, K-C., Yang, Y-K., Chen, S. H., Hong, J. S. & Lu, R-B., 2018 Oct 1, In : Drug and Alcohol Dependence. 191, p. 6-13 8 p.

Research output: Contribution to journal › Article

Methadone

Brain-Derived Neurotrophic Factor

Opioid Analgesics

Cytokines

Data storage equipment

Physiological Concentration of Prostaglandin E ₂ Exerts Anti-inflammatory Effects by Inhibiting Microglial Production of Superoxide Through a Novel Pathway

Chen, S. H., Sung, Y. F., Oyarzabal, E. A., Tan, Y. M., Leonard, J., Guo, M., Li, S., Wang, Q., Chu, C-H., Chen, S. L., Lu, R-B. & Hong, J. S., 2018 Oct 1, In : Molecular Neurobiology. 55, 10, p. 8001-8013 13 p.

Research output: Contribution to journal › Article

Prostaglandins E

Dinoprostone

Superoxides

Anti-Inflammatory Agents

Neuroprotective Agents

6 Citations (Scopus)

WWOX phosphorylation, signaling, and role in neurodegeneration

Liu, C. C., Ho, P. C., Lee, I. T., Chen, Y. A., Chu, C. H., Teng, C. C., Wu, S. N., Sze, C. I., Chiang, M. F. & Chang, N. S., 2018 Aug 15, In : Frontiers in Neuroscience. 12, AUG, 563.

Research output: Contribution to journal › Review article

Amyloid

Phosphorylation

Genetic Suppression

Glycogen Synthase Kinase 3

Proteins

Thesis

The effects of TIAM2S gene on brain development plasticity and behavioral traits

Author: 愉雅, 蘇., 2017 Aug 28

Supervisor: Chu, C. (Supervisor)

Student thesis: Master's Thesis

TIAM2S exaggerates neuron-inflammation and neural damage through microglial priming

Author: 威仁, 盧., 2019

Supervisor: Chu, C. (Supervisor)

Student thesis: Master's Thesis