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Research Output 2001 2020

2020

Bile acid and bile acid transporters are involved in the pathogenesis of acute hepatopancreatic necrosis disease in white shrimp Litopenaeus vannamei

Kumar, R., Ng, T. H., Chang, C. C., Tung, T. C., Lin, S. S., Lo, C. F. & Wang, H. C., 2020 Jan 1, In : Cellular Microbiology. 22, 1, e13127.

Research output: Contribution to journalArticle

Bile Acids and Salts
Necrosis
Vibrio parahaemolyticus
Stomach
Bacterial Secretion Systems
2019
Open Access
White spot syndrome virus 1
Hemocytes
Virus Replication
Glutamine
Genome

ICTV virus taxonomy profile: Nimaviridae

ICTV Report Consortium, 2019 Jul, In : Journal of General Virology. 100, 7, p. 1053-1054 2 p.

Research output: Contribution to journalArticle

Open Access
Nimaviridae
White spot syndrome virus 1
Viruses
Dental Caries
Virus Diseases
4 Citations (Scopus)

LvRas and LvRap are both important for WSSV replication in Litopenaeus vannamei

Tseng, Y. T., Kumar, R. & Wang, H. C., 2019 May, In : Fish and Shellfish Immunology. 88, p. 150-160 11 p.

Research output: Contribution to journalArticle

White spot syndrome virus
Litopenaeus vannamei
virus replication
Viruses
virus

Selective expression of a “correct cloud” of Dscam in crayfish survivors after second exposure to the same pathogen

Ng, T. H., Kumar, R., Apitanyasai, K., He, S. T., Chiu, S. P. & Wang, H. C., 2019 Sep, In : Fish and Shellfish Immunology. 92, p. 430-437 8 p.

Research output: Contribution to journalArticle

Down syndrome
Cell Adhesion Molecules
Pathogens
crayfish
adhesion
3 Citations (Scopus)

Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirAvp and pirBvp toxins and activation of the cry-like pore-forming domain

Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., 2019 Apr, In : Toxins. 11, 4, 233.

Research output: Contribution to journalArticle

Open Access
Vibrio parahaemolyticus
Penaeidae
Chemical activation
Necrosis
Hepatopancreas

The gene structure and hypervariability of the complete Penaeus monodon Dscam gene

Apitanyasai, K., Huang, S. W., Ng, T. H., He, S. T., Huang, Y. H., Chiu, S. P., Tseng, K. C., Lin, S. S., Chang, W. C., Baldwin-Brown, J. G., Long, A. D., Lo, C. F., Yu, H. T. & Wang, H. C., 2019 Dec 1, In : Scientific reports. 9, 1, 16595.

Research output: Contribution to journalArticle

Open Access
Penaeidae
Exons
Genes
Alternative Splicing
Tail
1 Citation (Scopus)

The Pathobiome in Animal and Plant Diseases

Bass, D., Stentiford, G. D., Wang, H. C., Koskella, B. & Tyler, C. R., 2019 Nov, In : Trends in Ecology and Evolution. 34, 11, p. 996-1008 13 p.

Research output: Contribution to journalReview article

Open Access
animal diseases
plant diseases and disorders
symbiont
symbionts
etiology
2018
4 Citations (Scopus)
Vibrio parahaemolyticus
Vietnam
Necrosis
Genome
Genes
5 Citations (Scopus)

The Rho signalling pathway mediates the pathogenicity of AHPND-causing V. parahaemolyticus in shrimp

Ng, T. H., Lu, C. W., Lin, S. S., Chang, C. C., Tran, L. H., Chang, W. C., Lo, C. F. & Wang, H. C., 2018 Aug, In : Cellular Microbiology. 20, 8, e12849.

Research output: Contribution to journalArticle

Virulence
Necrosis
Hepatopancreas
Stomach
Genes
12 Citations (Scopus)

What vaccination studies tell us about immunological memory within the innate immune system of cultured shrimp and crayfish

Chang, Y. H., Kumar, R., Ng, T. H. & Wang, H. C., 2018 Mar, In : Developmental and Comparative Immunology. 80, p. 53-66 14 p.

Research output: Contribution to journalArticle

Immunologic Memory
Astacoidea
Immune System
Vaccination
Inactivated Vaccines
2017
2 Citations (Scopus)
Oryzias
Interferon Type I
Interferons
Antiviral Agents
Fishes
12 Citations (Scopus)

Dscam1 in pancrustacean immunity: Current status and a look to the future

Armitage, S. A. O., Kurtz, J., Brites, D., Dong, Y., Pasquier, L. D. & Wang, H. C., 2017 Jun 9, In : Frontiers in Immunology. 8, JUN, 662.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Down Syndrome
Immunity
Insects
Genes
32 Citations (Scopus)

Microbiome Dynamics in a Shrimp Grow-out Pond with Possible Outbreak of Acute Hepatopancreatic Necrosis Disease

Chen, W. Y., Ng, T. H., Wu, J. H., Chen, J. W. & Wang, H. C., 2017 Dec 1, In : Scientific reports. 7, 1, 9395.

Research output: Contribution to journalArticle

Microbiota
Disease Outbreaks
Necrosis
Stomach
Vibrio
1 Citation (Scopus)

Resonant Dipolar Coupling of Microwaves with Confined Acoustic Vibrations in a Rod-shaped Virus

Sun, C. K., Tsai, Y. C., Chen, Y. J. E., Liu, T. M., Chen, H. Y., Wang, H. C. & Lo, C. F., 2017 Dec 1, In : Scientific reports. 7, 1, 4611.

Research output: Contribution to journalArticle

viruses
sound waves
rods
microwaves
microwave absorption
6 Citations (Scopus)

Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin-mutated F4 medaka (Oryzias latipes)

Yeh, Y. C., Kinoshita, M., Ng, T. H., Chang, Y. H., Maekawa, S., Chiang, Y. A., Aoki, T. & Wang, H. C., 2017 Dec 1, In : Scientific reports. 7, 1, 11435.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Myostatin
Oryzias
Fishes
Growth
2016

A member of the immunoglobulin superfamily, orange-spotted grouper novel immune gene EcVig, is induced by immune stimulants and type I interferon

Yeh, Y. C., Wang, T. Y., Chou, H. Y., Lin, H. Y., Chen, T. Y., Aoki, T. & Wang, H. C., 2016 Nov 1, In : Fish and Shellfish Immunology. 58, p. 415-422 8 p.

Research output: Contribution to journalArticle

Epinephelus coioides
Interferon Type I
grouper
interferons
Viruses
11 Citations (Scopus)

Expression and biological activity of two types of interferon genes in medaka (Oryzias latipes)

Maekawa, S., Chiang, Y. A., Hikima, J. I., Sakai, M., Lo, C. F., Wang, H. C. & Aoki, T., 2016 Jan 1, In : Fish and Shellfish Immunology. 48, p. 20-29 10 p.

Research output: Contribution to journalArticle

Oryzias latipes
interferons
Bioactivity
Interferons
bioactive properties
5 Citations (Scopus)

Replication of the shrimp virus WSSV depends on glutamate-driven anaplerosis

Li, C. Y., Wang, Y. J., Huang, S. W., Cheng, C. S. & Wang, H. C., 2016 Jan 11, In : PloS one. 11, 1, e0146902.

Research output: Contribution to journalArticle

White spot syndrome virus 1
White spot syndrome virus
Virus Replication
Viruses
glutamates
16 Citations (Scopus)

Six Hours after Infection, the Metabolic Changes Induced by WSSV Neutralize the Host's Oxidative Stress Defenses

Chen, I. T., Lee, D. Y., Huang, Y. T., Kou, G. H., Wang, H. C., Chang, G. D. & Lo, C. F., 2016 Jun 9, In : Scientific reports. 6, 27732.

Research output: Contribution to journalArticle

Reactive Oxygen Species
Oxidative Stress
Glycolysis
Infection
Phosphatidylinositol 3-Kinases

Structure resonance energy transfer from em wave to rod-like virus

Sun, C. K., Tsai, Y. C., Kao, C. L., Wang, H. C., Lo, C. F. & Chen, Y. J., 2016 Nov 28, 41st International Conference on Infrared, Millimeter and Terahertz Waves, IRMMW-THz 2016. IEEE Computer Society, 7758349. (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz; vol. 2016-November).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Viruses
Energy transfer
Electromagnetic waves
Electromagnetic wave absorption
Absorption spectra
14 Citations (Scopus)

TALENs-mediated gene disruption of myostatin produces a larger phenotype of medaka with an apparently compromised immune system

Chiang, Y. A., Kinoshita, M., Maekawa, S., Kulkarni, A., Lo, C-F., Yoshiura, Y., Wang, H-C. & Aoki, T., 2016 Jan 1, In : Fish and Shellfish Immunology. 48, p. 212-220 9 p.

Research output: Contribution to journalArticle

Myostatin
myostatin
Immune system
immune system
gene targeting
2015
5 Citations (Scopus)

A novel detection platform for shrimp white spot syndrome virus using an ICP11-dependent immunomagnetic reduction (IMR) assay

Liu, B. H., Lin, Y. C., Ho, C. S., Yang, C. C., Chang, Y. T., Chang, J. F., Li, C. Y., Cheng, C. S., Huang, J. Y., Lee, Y. F., Hsu, M. H., Lin, F. C., Wang, H. C., Lo, C. F., Yang, S. Y. & Wang, H. C., 2015 Sep 18, In : PLoS ONE. 10, 9, e0138207.

Research output: Contribution to journalArticle

White spot syndrome virus 1
White spot syndrome virus
Viruses
Assays
shrimp
5 Citations (Scopus)

Erratum: The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin (Proceedings of the National Academy of Sciences of the United States of America (2015) 112 (10798-10803))

Lee, C. T., Chen, I. T., Yang, Y. T., Ko, T. P., Huang, Y. T., Huang, J. Y., Huang, M. F., Lin, S. J., Chen, C. Y., Lin, S. S., Lightner, D. V., Wang, H. C., Wang, A. H. J., Wang, H. C., Hor, L. I. & Lo, C. F., 2015 Sep 29, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 39, p. E5445

Research output: Contribution to journalComment/debate

66 Citations (Scopus)

Pathogenesis of acute hepatopancreatic necrosis disease (AHPND) in shrimp

Lai, H. C., Ng, T. H., Ando, M., Lee, C. T., Chen, I. T., Chuang, J. C., Mavichak, R., Chang, S. H., Yeh, M. D., Chiang, Y. A., Takeyama, H., Hamaguchi, H. O., Lo, C. F., Aoki, T. & Wang, H. C., 2015 Dec 1, In : Fish and Shellfish Immunology. 47, 2, p. 1006-1014 9 p.

Research output: Contribution to journalArticle

necrosis
shrimp
pathogenesis
toxin
toxins
8 Citations (Scopus)

Reprint of "Review of Dscam-mediated immunity in shrimp and other arthropods"

Ng, T. H., Chiang, Y. A., Yeh, Y. C. & Wang, H. C., 2015 Feb 1, In : Developmental and Comparative Immunology. 48, 2, p. 306-314 9 p.

Research output: Contribution to journalReview article

Arthropods
Cell Adhesion Molecules
Down Syndrome
Immunity
Invertebrates
11 Citations (Scopus)

The DNA fibers of shrimp hemocyte extracellular traps are essential for the clearance of Escherichia coli

Ng, T. H., Wu, M. H., Chang, S. H., Aoki, T. & Wang, H. C., 2015 Jan 1, In : Developmental and Comparative Immunology. 48, 1, p. 229-233 5 p.

Research output: Contribution to journalArticle

Hemocytes
Escherichia coli
DNA
Vertebrates
Extracellular Traps
163 Citations (Scopus)

The opportunistic marine pathogen Vibrio parahaemolyticus becomes virulent by acquiring a plasmid that expresses a deadly toxin

Lee, C. T., Chen, I. T., Yang, Y. T., Ko, T. P., Huang, Y. T., Huang, J. Y., Huang, M. F., Lin, S. J., Chen, C. Y., Lin, S. S., Lightner, D. V., Wang, H. C., Wang, A. H. J., Wang, H. C., Hor, L. I. & Lo, C. F., 2015 Aug 25, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 34, p. 10798-10803 6 p.

Research output: Contribution to journalArticle

Vibrio parahaemolyticus
Plasmids
Necrosis
Photorhabdus
Penaeidae
21 Citations (Scopus)

To complete its replication cycle, a shrimp virus changes the population of long chain fatty acids during infection via the PI3K-Akt-mTOR-HIF1α pathway

Hsieh, Y. C., Chen, Y. M., Li, C. Y., Chang, Y. H., Liang, S. Y., Lin, S. Y., Lin, C. Y., Chang, S. H., Wang, Y. J., Khoo, K. H., Aoki, T. & Wang, H. C., 2015 Jan 1, In : Developmental and Comparative Immunology. 53, 1, p. 85-95 11 p.

Research output: Contribution to journalArticle

White spot syndrome virus 1
Phosphatidylinositol 3-Kinases
Fatty Acids
Viruses
Infection
Vibrio
Cell Adhesion Molecules
Down Syndrome
Protein Isoforms
Recombinant Proteins
2014
62 Citations (Scopus)

An Invertebrate Warburg Effect: A Shrimp Virus Achieves Successful Replication by Altering the Host Metabolome via the PI3K-Akt-mTOR Pathway

Su, M. A., Huang, Y. T., Chen, I. T., Lee, D. Y., Hsieh, Y. C., Li, C. Y., Ng, T. H., Liang, S. Y., Lin, S. Y., Huang, S. W., Chiang, Y. A., Yu, H. T., Khoo, K. H., Chang, G. D., Lo, C. F. & Wang, H. C., 2014 Jun, In : PLoS pathogens. 10, 6, e1004196.

Research output: Contribution to journalArticle

White spot syndrome virus 1
Metabolome
Invertebrates
Phosphatidylinositol 3-Kinases
Viruses
68 Citations (Scopus)

Draft genome sequences of four strains of Vibrio parahaemolyticus, three of which cause early mortality syndrome/acute hepatopancreatic necrosis disease in shrimp in China and Thailand

Yang, Y. T., Chen, I. T., Lee, C. T., Chen, C. Y., Lin, S. S., Hor, L. I., Tseng, T. C., Huang, Y. T., Sritunyalucksana, K., Thitamadee, S., Wang, H. C. & Lo, C. F., 2014 Jan 1, In : Genome Announcements. 2, 5, e00816-14.

Research output: Contribution to journalArticle

Photorhabdus
Vibrio parahaemolyticus
Cholera Toxin
Thailand
Sequence Analysis
9 Citations (Scopus)

EcVig, a novel grouper immune-gene associated with antiviral activity against NNV infection

Yeh, Y. C., Hsu, Y. J., Chen, Y. M., Lin, H. Y., Yang, H. L., Chen, T. Y. & Wang, H. C., 2014 Mar 1, In : Developmental and Comparative Immunology. 43, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

Virus Diseases
Antiviral Agents
Oncorhynchus mykiss
Necrosis
Viruses
37 Citations (Scopus)

Review of Dscam-mediated immunity in shrimp and other arthropods

Ng, T. H., Chiang, Y. A., Yeh, Y. C. & Wang, H. C., 2014 Oct, In : Developmental and Comparative Immunology. 46, 2, p. 129-138 10 p.

Research output: Contribution to journalReview article

Arthropods
Cell Adhesion Molecules
Down Syndrome
Immunity
Invertebrates
29 Citations (Scopus)

Validation of a commercial insulated isothermal PCR-based POCKIT test for rapid and easy detection of white spot syndrome virus infection in Litopenaeus vannamei

Tsai, Y. L., Wang, H. C., Lo, C. F., Tang-Nelson, K., Lightner, D., Ou, B. R., Hour, A. L., Tsai, C. F., Yen, C. C., Chang, H. F. G., Teng, P. H. & Lee, P. Y., 2014 Mar 13, In : PloS one. 9, 3, e90545.

Research output: Contribution to journalArticle

White spot syndrome virus 1
White spot syndrome virus
Litopenaeus vannamei
Virus Diseases
Viruses
12 Citations (Scopus)

WSSV-induced crayfish Dscam shows durable immune behavior

Ng, T. H., Hung, H. Y., Chiang, Y. A., Lin, J. H., Chen, Y. N., Chuang, Y. C. & Wang, H. C., 2014 Sep, In : Fish and Shellfish Immunology. 40, 1, p. 78-90 13 p.

Research output: Contribution to journalArticle

Down syndrome
Cell Adhesion Molecules
crayfish
adhesion
Viruses
2013
29 Citations (Scopus)

Properties of Litopenaeus vannamei Dscam (LvDscam) isoforms relatedto specific pathogen recognition

Hung, H. Y., Ng, T. H., Lin, J. H., Chiang, Y. A., Chuang, Y. C. & Wang, H. C., 2013 Oct, In : Fish and Shellfish Immunology. 35, 4, p. 1272-1281 10 p.

Research output: Contribution to journalArticle

Down syndrome
Litopenaeus vannamei
Cell Adhesion Molecules
Pathogens
adhesion
27 Citations (Scopus)

Shrimp Dscam and its cytoplasmic tail splicing activator serine/arginine (SR)-rich protein B52 were both induced after white spot syndrome virus challenge

Chiang, Y. A., Hung, H. Y., Lee, C. W., Huang, Y. T. & Wang, H-C., 2013 Jan 1, In : Fish and Shellfish Immunology. 34, 1, p. 209-219 11 p.

Research output: Contribution to journalArticle

Down syndrome
White spot syndrome virus
alternative splicing
Alternative Splicing
Cell Adhesion Molecules
33 Citations (Scopus)

Shrimp hemocytes release extracellular traps that kill bacteria

Ng, T. H., Chang, S. H., Wu, M. H. & Wang, H-C., 2013 Dec 1, In : Developmental and Comparative Immunology. 41, 4, p. 644-651 8 p.

Research output: Contribution to journalArticle

Hemocytes
Bacteria
Escherichia coli
Histones
Vertebrates
10 Citations (Scopus)

The DNA virus white spot syndrome virus uses an internal ribosome entry site for translation of the highly expressed nonstructural protein ICP35

Kang, S. T., Wang, H. C., Yang, Y. T., Kou, G. H. & Lo, C. F., 2013 Dec 1, In : Journal of Virology. 87, 24, p. 13263-13278 16 p.

Research output: Contribution to journalArticle

White spot syndrome virus 1
DNA viruses
White spot syndrome virus
DNA Viruses
ribosomes
2012
2 Citations (Scopus)

Feeding hermit crabs to shrimp broodstock increases their risk of WSSV infection

Chang, Y. S., Liu, W. J., Chen, T. C., Chan, T. Y., Liu, K. F., Chuang, J. C., Kou, G. H., Lo, C. F. & Wang, H. C., 2012 Apr 26, In : Diseases of Aquatic Organisms. 98, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

White spot syndrome virus
breeding stock
crab
crabs
virus
12 Citations (Scopus)

Heterogeneous nuclear ribonucleoprotein hrp36 acts as an alternative splicing repressor in Litopenaeus vannamei Dscam

Lee, C. W., Chen, I. T., Chou, P. H., Hung, H. Y. & Wang, KC. H. C., 2012 Jan 1, In : Developmental and Comparative Immunology. 36, 1, p. 10-20 11 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
Alternative Splicing
Cell Adhesion Molecules
Down Syndrome
Drosophila
6 Citations (Scopus)

Identification and characterization of DSCAM isoforms isolated from orange-spotted grouper Epinephelus coioides

Yeh, Y. C., Lee, C. W., Pan, Y. W., Hsu, Y. J., Hung, H. Y., Chen, Y. M., Lin, H. Y., Chen, T. Y., Yang, H. L. & Wang, H. C., 2012 Sep 1, In : Developmental and Comparative Immunology. 38, 1, p. 148-159 12 p.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Down Syndrome
Protein Isoforms
Optic Nerve Injuries
Vertebrates
13 Citations (Scopus)

Penaeus monodon thioredoxin restores the DNA binding activity of oxidized white spot syndrome virus IE1

Huang, J. Y., Liu, W. J., Wang, H. C., Lee, D. Y., Leu, J. H., Wang, H. C., Tsai, M. H., Kang, S. T., Chen, I. T., Kou, G. H., Chang, G. D. & Lo, C. F., 2012 Sep 15, In : Antioxidants and Redox Signaling. 17, 6, p. 914-926 13 p.

Research output: Contribution to journalArticle

White spot syndrome virus 1
Penaeidae
Thioredoxins
Immediate-Early Genes
Viruses
11 Citations (Scopus)

Spawning stress triggers WSSV replication in brooders via the activation of shrimp STAT

Lin, S. J., Hsia, H. L., Liu, W. J., Huang, J. Y., Liu, K. F., Chen, W. Y., Yeh, Y. C., Huang, Y. T., Lo, C. F., Kou, G. H. & Wang, H. C., 2012 Sep 1, In : Developmental and Comparative Immunology. 38, 1, p. 128-135 8 p.

Research output: Contribution to journalArticle

Dental Caries
Densovirinae
Disease Outbreaks
White spot syndrome virus 1
Aquaculture
2011
15 Citations (Scopus)

An oral nervous necrosis virus vaccine using Vibrio anguillarum as an expression host provides early protection

Chen, Y-M., Shih, C. H., Liu, H. C., Wu, C. L., Lin, C. C., Wang, H-C., Chen, T-Y., Yang, H. L. & Lin, J. H. Y., 2011 Nov 16, In : Aquaculture. 321, 1-2, p. 26-33 8 p.

Research output: Contribution to journalArticle

Vibrio anguillarum
vaccine
mouth
virus
necrosis
30 Citations (Scopus)

Microarray Analyses of Shrimp Immune Responses

Aoki, T., Wang, H. C., Unajak, S., Santos, M. D., Kondo, H. & Hirono, I., 2011 Aug 1, In : Marine Biotechnology. 13, 4, p. 629-638 10 p.

Research output: Contribution to journalReview article

Roniviridae
White spot syndrome virus 1
Oxolinic Acid
Oxytetracycline
Aquaculture
40 Citations (Scopus)

Penaeus monodon Dscam (PmDscam) has a highly diverse cytoplasmic tail and is the first membrane-bound shrimp Dscam to be reported

Chou, P. H., Chang, H. S., Chen, I. T., Lee, C. W., Hung, H. Y. & Han-Ching Wang, K. C., 2011 Jan 1, In : Fish and Shellfish Immunology. 30, 4-5, p. 1109-1123 15 p.

Research output: Contribution to journalArticle

Down syndrome
Penaeus monodon
Cell Adhesion Molecules
adhesion
cell adhesion
16 Citations (Scopus)

Penaeus monodon TATA box-binding protein interacts with the white spot syndrome virus transactivator IE1 and promotes its transcriptional activity

Liu, W. J., Chang, Y. S., Huang, W. T., Chen, I. T., Wang, K. C. H. C., Kou, G. H. & Lo, C. F., 2011 Jul 1, In : Journal of Virology. 85, 13, p. 6535-6547 13 p.

Research output: Contribution to journalArticle

White spot syndrome virus 1
TATA-Box Binding Protein
Penaeidae
TATA box
White spot syndrome virus
54 Citations (Scopus)

The expression of two novel orange-spotted grouper (Epinephelus coioides) TNF genes in peripheral blood leukocytes, various organs, and fish larvae

Lam, F. W. S., Wu, S. Y., Lin, S. J., Lin, C. C., Chen, Y. M., Wang, H. C., Chen, T. Y., Lin, H. T. & Lin, J. H. Y., 2011 Feb, In : Fish and Shellfish Immunology. 30, 2, p. 618-629 12 p.

Research output: Contribution to journalArticle

Epinephelus coioides
tumor necrosis factors
fish larvae
tumor
Fish