Han-Sheng Chuang

Associate Professor

  • 689 Citations
  • 15 h-Index
19982020
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Research Output 1998 2019

2019
3 Citations (Scopus)

Development of a self-driving bioassay based on diffusion for simple detection of microorganisms

Wang, J., Chi, S., Shieh, D. & Chuang, H., 2019 Jan 1, In : Sensors and Actuators, B: Chemical. 278, p. 140-146

Research output: Contribution to journalArticle

1 Citation (Scopus)

Investigation of micro-volume viscosity with janus microbeads based on rotational brownian motion

Chen, C. J., Chen, W. L., Phong, P. H. & Chuang, H-S., 2019 Mar 1, In : Sensors (Switzerland). 19, 5, 1217.

Research output: Contribution to journalArticle

Open Access
Janus
Brownian movement
Microspheres
Viscosity
viscosity
1 Citation (Scopus)

Rapid and Sensitive Nano-Immunosensors for Botulinum

Cheng, H. P. & Chuang, H. S., 2019 Jul 26, In : ACS Sensors. 4, 7, p. 1754-1760 7 p.

Research output: Contribution to journalArticle

Immunosensors
Synaptosomal-Associated Protein 25
proteins
Proteins
Botulinum Toxins
2018
6 Citations (Scopus)

Contact-Lens Biosensors

Tseng, R., Chen, C., Hsu, S. & Chuang, H., 2018 Aug, In : Sensors. 18, 8, p. 2651

Research output: Contribution to journalArticle

10 Citations (Scopus)
Biomarkers
Diabetic Retinopathy
Gold
Nanoparticles
Tumor Necrosis Factor-alpha
5 Citations (Scopus)

Label-Free Monitoring of Microorganisms and Their Responses to Antibiotics Based on Self-Powered Microbead Sensors

Wang, J. C., Chi, S. W., Yang, T-H. & Chuang, H-S., 2018 Oct 26, In : ACS Sensors. 3, 10, p. 2182-2190 9 p.

Research output: Contribution to journalArticle

antibiotics
Antibiotics
microorganisms
Microorganisms
Labels
1 Citation (Scopus)

On-demand dielectrophoretic immobilization and high-resolution imaging of C. elegans in microfluids

Huang, L., Zhao, P., Wu, J., Chuang, H-S. & Wang, W., 2018 Apr 15, In : Sensors and Actuators, B: Chemical. 259, p. 703-708 6 p.

Research output: Contribution to journalArticle

immobilization
Imaging techniques
high resolution
Lab-on-a-chip
Electrodes
2017

A multi-functionally optoelectric platform for micro/nano particle manipulation and applications

Chuang, H-S., Lin, H. N. & Shieh, D-B., 2017 Jul 26, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems. Institute of Electrical and Electronics Engineers Inc., p. 472-475 4 p. 7994088. (TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomarkers
Sorting
manipulators
Agglomeration
platforms
1 Citation (Scopus)

Analyzing the locomotory gaitprint of Caenorhabditis elegans on the basis of empirical mode decomposition

Lin, L. C. & Chuang, H. S., 2017 Jul, In : PloS one. 12, 7, e0181469.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Decomposition
Gait
degradation
gait
8 Citations (Scopus)

Detection of low-abundance biomarker lipocalin 1 for diabetic retinopathy using optoelectrokinetic bead-based immunosensing

Wang, J. C., Ku, H. Y., Chen, T. & Chuang, H-S., 2017 Mar 15, In : Biosensors and Bioelectronics. 89, p. 701-709 9 p.

Research output: Contribution to journalArticle

Lipocalin 1
Biomarkers
Diabetic Retinopathy
Semiconductor quantum dots
Dyes

Development of a bead-based optoelectrokinetic immunosensing technique for detection of low-abundance analytes

Chuang, H-S., Lin, H. N. & Ku, H. Y., 2017 Jan 1, Symposia: Fluid Measurement and Instrumentation; Fluid Dynamics of Wind Energy; Renewable and Sustainable Energy Conversion; Energy and Process Engineering; Microfluidics and Nanofluidics; Development and Applications in Computational Fluid Dynamics; DNS/LES and Hybrid RANS/LES Methods. American Society of Mechanical Engineers (ASME), (American Society of Mechanical Engineers, Fluids Engineering Division (Publication) FEDSM; vol. 1B-2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomarkers
Frequency modulation
Laser beams
Electric fields
Irradiation
4 Citations (Scopus)
Poloxamer
worms
Hydrogel
immobilization
Hydrogels
8 Citations (Scopus)
Pseudomonas aeruginosa
Staphylococcus aureus
Anti-Bacterial Agents
Color
Bacterial Load
2016
13 Citations (Scopus)
Energy Transfer
beads
Energy transfer
Fluorescence
energy transfer

Brownian motion enabled rapid pathogens screening

Chen, Y. J. & Chuang, H-S., 2016 Jan 1, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 1659-1660 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Brownian movement
Pathogens
Screening
19 Citations (Scopus)

Exercise in an electrotactic flow chamber ameliorates age-related degeneration in Caenorhabditis elegans

Chuang, H-S., Kuo, W. J., Lee, C. L., Chu, I. H. & Chen, C-S., 2016 Jun 16, In : Scientific reports. 6, 28064.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Lipofuscin
Oxidative Stress
Neurosciences
Geriatrics
1 Citation (Scopus)

Immobilization of C. elegans in liquid using 3d-electrode dielectrophoresis

Zeng, X. Y., Huang, L., Chuang, H-S. & Wang, W. H., 2016 Jan 1, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 477-478 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Electrophoresis
Electrodes
Liquids
Microfluidics
Electric fields

Rapid and addressable immobilization of Caenorhabditis elegans in a thermo-reversible hydrogel enabled by an optoelectric microchip

Chuang, H-S. & Chuang, W. Y., 2016 Jan 1, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 481-482 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gelation
Hydrogels
Genetic engineering
Assays
Animals

Rapid and reversible immobilization of caenorhabditis elegans with an optoelectric device and pluronic F-127

Chuang, W. Y. & Chuang, H-S., 2016 Feb 26, MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems. Institute of Electrical and Electronics Engineers Inc., p. 769-771 3 p. 7421742. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); vol. 2016-February).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Poloxamer
worms
immobilization
progeny
gelation
17 Citations (Scopus)

Rapid bead-based antimicrobial susceptibility testing by optical diffusometry

Chung, C. Y., Wang, J. C. & Chuang, H. S., 2016 Feb, In : PloS one. 11, 2, e0148864.

Research output: Contribution to journalArticle

Bacteria
anti-infective agents
Microorganisms
bacteria
Testing

Virus Purification by bead-based immunoreaction and rapid electrokinetic patterning

Chen, A. Y. & Chuang, H-S., 2016 Jan 1, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 1535-1536 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Viruses
Purification
Sorting
Antibodies
Surface properties
2015

Development of an image-based algorithm for the motility characterizations of the nematode caenorhabditis elegans

Kuo, W. J., Chuang, H-S. & Chuang, H. S., 2015 Jan 1, 1st Global Conference on Biomedical Engineering and 9th Asian-Pacific Conference on Medical and Biological Engineering. Wang, S-H., Su, F-C. & Yeh, M-L. (eds.). Springer Verlag, p. 107-110 4 p. (IFMBE Proceedings; vol. 47).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Animals
Flow visualization
Velocity measurement
Tapes
Propulsion
4 Citations (Scopus)

Numerical simulation on the opto-electro-kinetic patterning for rapid concentration of particles in a microchannel

Kim, D., Shim, J., Chuang, H-S. & Kim, K. C., 2015 Jan 1, In : Biomicrofluidics. 9, 3, 034102.

Research output: Contribution to journalArticle

microchannels
Microchannels
Electrophoresis
alternating current
Lasers
2014
11 Citations (Scopus)

A micro-volume viscosity measurement technique based on μPIV diffusometry

Sie, Y. S. & Chuang, H-S., 2014 Jan 1, In : Microfluidics and Nanofluidics. 16, 1-2, p. 65-72 8 p.

Research output: Contribution to journalArticle

Volume measurement
Viscosity measurement
particle image velocimetry
Viscosity
viscosity
27 Citations (Scopus)

An optoelectrokinetic technique for programmable particle manipulation and bead-based biosignal enhancement

Wang, K. C., Kumar, A., Williams, S. J., Green, N. G., Kim, K. C. & Chuang, H-S., 2014 Oct 21, In : Lab on a Chip. 14, 20, p. 3958-3967 10 p.

Research output: Contribution to journalArticle

Bioassay
Biological Assay
Streptavidin
Biomarkers
Biotin
5 Citations (Scopus)
worms
Rheology
Caenorhabditis elegans
particle image velocimetry
propulsion
5 Citations (Scopus)

Compact and tunable size-based dielectrophoretic flow fractionation

Chuang, H. S., Chung, T. Y. & Li, Y., 2014 Dec 1, In : Journal of Micromechanics and Microengineering. 24, 12, 125016.

Research output: Contribution to journalArticle

Fractionation
Sorting
Electrodes
Polystyrenes
Electrophoresis
4 Citations (Scopus)

Effect of array and shape of insulating posts on proteins focusing by direct current dielectrophoresis

Kim, D., Shim, J., Chuang, H-S. & Kim, K. C., 2014 Jan 1, In : Journal of Mechanical Science and Technology. 28, 7, p. 2629-2636 8 p.

Research output: Contribution to journalArticle

Electrophoresis
Proteins
Electric potential
Microchannels
Conservation

Optoelectrokinetically-Enabled Signal Enhancement for a Bead-Based FRET Fluorescence Immunoassay

Chuang, H-S., Wang, K. C., Hsieh, D. B. & Fu, Y. Q., 2014, 2014 International Symposium on Optomechatronic Technologies, ISOT 2014. Institute of Electrical and Electronics Engineers Inc., p. 101-104 4 p. 7119396

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Energy transfer
Biomarkers
Antigens
Electrodes
Fluorescence Resonance Energy Transfer

Rapid and dynamic signal enhancement of bead-based bioassays using a multi-functional optoelectric device

Wang, K. C., Li, F. T., Shieh, D-B., Kim, K. C. & Chuang, H-S., 2014 Jan 1, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, p. 1554-1556 3 p. (18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bioassay
Sorting
Demonstrations
Agglomeration
Tuning
2013
22 Citations (Scopus)

Caenorhabditis-in-drop array for monitoring C. elegans quiescent behavior

Belfer, S. J., Chuang, H. S., Freedman, B. L., Yuan, J., Norton, M., Bau, H. H. & Raizen, D. M., 2013 May 1, In : Sleep. 36, 5, p. 689-698 10 p.

Research output: Contribution to journalArticle

Caenorhabditis
Cyclic AMP-Dependent Protein Kinases
Epidermal Growth Factor
Mutation
Agar

Dynamic particle concentration for bio-signal enhancement based on an optoelectric microchip

Wang, K. C., Wereley, S. T., Kumar, A. & Chuang, H-S., 2013 Jan 1, Fluids Engineering Systems and Technologies. American Society of Mechanical Engineers (ASME), (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); vol. 7 B).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Citations (Scopus)

Immobilization of the nematode caenorhabditis elegans with addressable light-induced heat knockdown (ALINK)

Chuang, H-S., Chen, H. Y., Chen, C-S. & Chiu, W-T., 2013 Aug 7, In : Lab on a Chip. 13, 15, p. 2980-2989 10 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Immobilization
Hot Temperature
Light
ITO glass
16 Citations (Scopus)

Shear-induced detachment of biofilms from hollow fiber silicone membranes

Huang, Z., Mclamore, E. S., Chuang, H. S., Zhang, W., Wereley, S., Leon, J. L. C. & Banks, M. K., 2013 Feb 1, In : Biotechnology and Bioengineering. 110, 2, p. 525-534 10 p.

Research output: Contribution to journalArticle

Biofilms
Silicones
Membranes
Fibers
Shear stress
14 Citations (Scopus)

Software-programmable continuous-flow multi-purpose lab-on-a-chip

Amin, A. M., Thakur, R., Madren, S., Chuang, H-S., Thottethodi, M., Vijaykumar, T. N., Wereley, S. T. & Jacobson, S. C., 2013 Nov 1, In : Microfluidics and Nanofluidics. 15, 5, p. 647-659 13 p.

Research output: Contribution to journalArticle

Lab-on-a-chip
high level languages
chips
computer programs
Assays
2012

Addressable light-induced heat knockdown (aLINK) for caenorhabditis (C.) elegans immobilization

Chuang, H. S., Chiu, W. T. & Chen, C. S., 2012 Jan 1, Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, p. 365-367 3 p. (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Animals
Microfluidics
Hot Temperature
Temperature
4 Citations (Scopus)

Characterizations of gas purge valves for liquid alignment and gas removal in a microfluidic chip

Chuang, H-S., Thakur, R. & Wereley, S. T., 2012 Aug 1, In : Journal of Micromechanics and Microengineering. 22, 8, 085023.

Research output: Contribution to journalArticle

Microfluidics
Gases
Liquids
Permeation
Polydimethylsiloxane
48 Citations (Scopus)

Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow

Zhou, J., Lee, P. L., Tsai, C. S., Lee, C. I., Yang, T. L., Chuang, H-S., Lin, W. W., Lin, T. E., Lim, S. H., Wei, S. Y., Chen, Y. L., Chien, S. & Chiu, J. J., 2012 May 15, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 20, p. 7770-7775 6 p.

Research output: Contribution to journalArticle

Cell Cycle
Endothelial Cells
Thoracic Aorta
Bone Morphogenetic Protein Receptors
Cyclin A
9 Citations (Scopus)

Nano-resolution flow measurement based on single pixel evaluation PIV

Chuang, H. S., Gui, L. & Wereley, S. T., 2012 Jul 1, In : Microfluidics and Nanofluidics. 13, 1, p. 49-64 16 p.

Research output: Contribution to journalArticle

flow measurement
Flow measurement
particle image velocimetry
Pixels
pixels
2011
29 Citations (Scopus)

Dielectrophoresis of Caenorhabditis elegans

Chuang, H-S., Raizen, D. M., Lamb, A., Dabbish, N. & Bau, H. H., 2011 Feb 21, In : Lab on a Chip. 11, 4, p. 599-604 6 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Electrophoresis
Nervous System
Electric fields
Light
1 Citation (Scopus)

Electro-worming: The behaviors of Caenorhabditis (C.) elegans in DC and AC electric fields

Chuang, H-S., Raizen, D. M., Dabbish, N. & Bau, H. H., 2011 Jan 1, In : Physics of Fluids. 23, 9, 091107.

Research output: Contribution to journalComment/debate

alternating current
direct current
electric fields
48 Citations (Scopus)

Hybrid opto-electric manipulation in microfluidics - Opportunities and challenges

Kumar, A., Williams, S. J., Chuang, H. S., Green, N. G. & Wereley, S. T., 2011 Jul 7, In : Lab on a Chip. 11, 13, p. 2135-2148 14 p.

Research output: Contribution to journalReview article

Microfluidics
Nanofluidics
Light modulation
Modulation
Fluids
2010
5 Citations (Scopus)

A diffusion-based cyclic particle extractor

Chuang, H-S., Jacobson, S. C. & Wereley, S. T., 2010 Oct 1, In : Microfluidics and Nanofluidics. 9, 4-5, p. 743-753 11 p.

Research output: Contribution to journalArticle

cycles
costs
particle diffusion
Polystyrenes
diffusion length

An automated cyclic particle extractor

Chuang, H-S., Wereley, S. T. & Jacobson, S. C., 2010 Jan 1, Proceedings of the ASME International Mechanical Engineering Congress and Exposition 2009, IMECE 2009. PART B ed. American Society of Mechanical Engineers (ASME), p. 567-570 4 p. (ASME International Mechanical Engineering Congress and Exposition, Proceedings; vol. 12, no. PART B).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Pneumatics
Flow rate
Pumps
21 Citations (Scopus)

Dynamic manipulation by light and electric fields: Micrometer particles to microliter droplets

Kumar, A., Chuang, H-S. & Wereley, S. T., 2010 Jun 1, In : Langmuir. 26, 11, p. 7656-7660 5 p.

Research output: Contribution to journalArticle

micrometers
manipulators
Electric fields
electric fields
active control

Microfluidic gas purge valves

Chuang, H. S. & Wereley, S. T., 2010 Jul 12, Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. p. 375-378 4 p. (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Gases
Fluids
Membranes
Permeation
8 Citations (Scopus)

Portable microfluidic cytometer for whole blood cell analysis

Grafton, M. M., Zordan, M. D., Chuang, H-S., Rajdev, P., Reece, L. M., Irazoqui, P. P., Wereley, S. T., Byrnes, R., Todd, P. & Leary, J. F., 2010 Dec 1, Microfluidics, BioMEMS, and Medical Microsystems VIII. 75930M. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7593).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

blood cells
Microfluidics
blood
Blood Cells
Blood
2009
55 Citations (Scopus)
Temperature sensors
Polydimethylsiloxane
Heating
Fabrication
Powders
14 Citations (Scopus)

Investigation of fluid flow out of a microcavity using μ piv

Wang, C. P., Sadeghi, F., Wereley, S. T. & Chuang, H-S., 2009 Jan 1, In : Tribology Transactions. 52, 6, p. 817-832 16 p.

Research output: Contribution to journalArticle

Microcavities
fluid flow
Flow of fluids
shear
Flow fields