• 989 Citations
  • 16 h-Index
19942019
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Research Output 1994 2019

  • 989 Citations
  • 16 h-Index
  • 45 Article
  • 4 Review article
  • 1 Letter
2019
1 Citation (Scopus)
Fournier Gangrene
Survival
Mortality
Hospital Emergency Service
1 Citation (Scopus)

Management of nocturnal enuresis in Taiwan: Consensus statements of the Taiwan enuresis expert committee

Wang, T. M., Yang, S. S. D., Tsai, J. D., Yu, M. C., Chiou, Y. H., Chen, K. L., Cheng, H-L., Lin, J., Chen, H. W., Kuo, H. C. & Chen, S. C., 2019 Jun 1, In : Journal of the Formosan Medical Association. 118, 6, p. 965-972 8 p.

Research output: Contribution to journalReview article

Open Access
Nocturnal Enuresis
Enuresis
Taiwan
Consensus
Pediatrics
2018
5 Citations (Scopus)
Arsenic
Potable water
Drinking Water
arsenic
drinking water
Ureteral Neoplasms
Kidney
Therapeutics
Carcinoma
Ureter
2017
11 Citations (Scopus)

EMP1, EMP 2, and EMP3 as novel therapeutic targets in human cancer

Wang, Y. W., Cheng, H-L., Ding, Y. R., Chou, L. H. & Chow, N-H., 2017 Aug 1, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1868, 1, p. 199-211 13 p.

Research output: Contribution to journalReview article

Myelin Proteins
Suppressor Genes
Neoplasms
Tissue Distribution
Endometrial Neoplasms
3 Citations (Scopus)

The role of Lutheran/basal cell adhesion molecule in human bladder carcinogenesis

Chang, H. Y., Chang, H. M., Wu, T. J., Chaing, C. Y., Tzai, T. S., Cheng, H-L., Raghavaraju, G., Chow, N-H. & Liu, H-S., 2017 Aug 26, In : Journal of biomedical science. 24, 1, 61.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Carcinogenesis
Urinary Bladder
Cell adhesion
Cell Adhesion
Open Access
Abscess
Fistula
2015
4 Citations (Scopus)

Antiangiogenesis as the novel mechanism for justicidin A in the anticancer effect on human bladder cancer

Wang, Y. W., Chuang, J. J., Chang, T. Y., Won, S. J., Tsai, H-W., Lee, C-T., Cheng, H-L., Tzai, T. S., Liu, H-S. & Chow, N-H., 2015 Jan 1, In : Anti-Cancer Drugs. 26, 4, p. 428-436 9 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
SCID Mice
Justicia
Neoplasms
Cell Proliferation
1 Citation (Scopus)

Determinants of quality of life in prostate cancer patients: A single institute analysis

Kao, Y-L., Tsai, Y-S., Ou, F. Y., Syu, Y. J., Ou, J-H., Yang, W-H., Cheng, H-L., Tzai, T. S. & Wang, J-D., 2015 Dec 1, In : Urological Science. 26, 4, p. 254-258 5 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Quality of Life
Marital Status
Orgasm
Leisure Activities

Perfusion pressure flow study in the upper urinary tract

Cheng, H-L., 2015 Jun 1, In : Urological Science. 26, 2, p. 144-146 3 p.

Research output: Contribution to journalArticle

Open Access
Urinary Tract
Perfusion
Pressure
Hydronephrosis
Pathology
9 Citations (Scopus)

SH3BGRL3 Protein as a Potential Prognostic Biomarker for Urothelial Carcinoma: A Novel Binding Partner of Epidermal Growth Factor Receptor

Chiang, C. Y., Pan, C. C., Chang, H. Y., Lai, M-D., Tzai, T. S., Tsai, Y-S., Ling, P., Liu, H-S., Lee, B-F., Cheng, H-L., Ho, C-L., Chen, S-H. & Chow, N-H., 2015 Dec 15, In : Clinical Cancer Research. 21, 24, p. 5601-5611 11 p.

Research output: Contribution to journalArticle

src Homology Domains
Epidermal Growth Factor Receptor
Glutamic Acid
Biomarkers
Carcinoma
2014
17 Citations (Scopus)

Hypoxia promotes nuclear translocation and transcriptional function in the oncogenic tyrosine kinase RON

Chang, H. Y., Liu, H-S., Lai, M-D., Tsai, Y-S., Tzai, T. S., Cheng, H-L. & Chow, N-H., 2014 Aug 15, In : Cancer Research. 74, 16, p. 4549-4562 14 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Neoplasms
Cell Survival
Hypoxia-Inducible Factor 1
Receptor Protein-Tyrosine Kinases
1 Citation (Scopus)

Surgical indications for unilateral neonatal hydronephrosis in considering ureteropelvic junction obstruction

Cheng, H-L., 2014 Jan 1, In : Urological Science. 25, 3, p. 73-76 4 p.

Research output: Contribution to journalReview article

Open Access
Hydronephrosis
Kidney
Radioisotopes
Radioisotope Renography
Ultrasonography
22 Citations (Scopus)

Validation and simplification of Fournier's gangrene severity index

Lin, T-Y., Ou, J-H., Tzai, T. S., Tong, Y-C., Chang, C. C., Cheng, H-L., Yang, W-H. & Lin, Y., 2014 Jan 1, In : International Journal of Urology. 21, 7, p. 696-701 6 p.

Research output: Contribution to journalArticle

Fournier Gangrene
Hematocrit
Survivors
Mortality
Creatinine
2013
7 Citations (Scopus)

Epithelial membrane protein 2 is a prognostic indictor for patients with urothelial carcinoma of the upper urinary tract

Wang, Y. W., Li, W. M., Wu, W. J., Chai, C. Y., Chang, T. Y., Sun, Y., Cheng, C. J., Shiue, Y. L., Su, S. J., Cheng, H-L., Liu, H-S. & Chow, N-H., 2013 Sep 1, In : American Journal of Pathology. 183, 3, p. 709-719 11 p.

Research output: Contribution to journalArticle

Urinary Tract
Membrane Proteins
Carcinoma
Integrins
Severe Combined Immunodeficiency
14 Citations (Scopus)
Vesico-Ureteral Reflux
renal function
cohort studies
Cicatrix
Deterioration
2012
14 Citations (Scopus)
Meta-Analysis
Urinary Bladder
Confidence Intervals
Carcinoma
Urinary Bladder Neoplasms
2011
46 Citations (Scopus)

Non-inferiority of silodosin to tamsulosin in treating patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)

Yu, H. J., Lin, A. T. L., Yang, S. S. D., Tsui, K. H., Wu, H. C., Cheng, C. L., Cheng, H-L., Wu, T. T. & Chiang, P. H., 2011 Dec 1, In : BJU International. 108, 11, p. 1843-1848 6 p.

Research output: Contribution to journalArticle

tamsulosin
Lower Urinary Tract Symptoms
Prostatic Hyperplasia
Prostate
Blood Pressure
10 Citations (Scopus)

Urinary CD14 as a potential biomarker for benign prostatic hyperplasia - discovery by combining MALDI-TOF-based biostatistics and ESI-MS/MS-based stable-isotope labeling

Cheng, H-L., Huang, H. J., Ou, B. Y., Chow, N-H., Chen, Y. W., Tzai, T. S., Wu, C. J. & Chen, S-H., 2011 Apr 1, In : Proteomics - Clinical Applications. 5, 3-4, p. 121-132 12 p.

Research output: Contribution to journalArticle

Biostatistics
Isotope Labeling
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Prostatic Hyperplasia
Biomarkers
2010
30 Citations (Scopus)

An unusual function of RON receptor tyrosine kinase as a transcriptional regulator in cooperation with EGFR in human cancer cells

Liu, H. S., Hsu, P. Y., Lai, M. D., Chang, H. Y., Ho, C. L., Cheng, H. L., Chen, H. T., Lin, Y. J., Wu, T. J., Tzai, T. S. & Chow, N. H., 2010 May 24, In : Carcinogenesis. 31, 8, p. 1456-1464 9 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Urinary Bladder Neoplasms
Neoplasms
Starvation

Refeeding vessels on Doppler ultrasound as evidence of tumor component

Chou, H. H., Cheng, H-L., Tsai, H. M., Cheng, C-N. & Chiou, Y-Y., 2010 Apr 1, In : Pediatrics International. 52, 2

Research output: Contribution to journalArticle

Doppler Ultrasonography
X Ray Computed Tomography
Wilms Tumor
Kidney Neoplasms
Neoplasms
2008
9 Citations (Scopus)

Immunohistochemical detection of prostate-specific antigen expression in primary urothelial carcinoma of the urinary bladder

Chen, J. C., Ho, C-L., Tsai, H-W., Tzai, T. S., Liu, H-S., Chow, N-H., Yang, W-H. & Cheng, H-L., 2008 Nov 1, In : Anticancer research. 28, 6 B, p. 4149-4154 6 p.

Research output: Contribution to journalArticle

Prostate-Specific Antigen
Urinary Bladder
Carcinoma
Neoplasms
Serine Proteases
7 Citations (Scopus)

The Molecular Signature for Urothelial Carcinoma of the Upper Urinary Tract

Ho, C-L., Tzai, T. S., Chen, J. C., Tsai, H-W., Cheng, H-L., Eisenberger, C. F. & Chow, N-H., 2008 Mar 1, In : Journal of Urology. 179, 3, p. 1155-1159 5 p.

Research output: Contribution to journalArticle

Urinary Tract
Renal Cell Carcinoma
Loss of Heterozygosity
Carcinoma
Urine
2006
29 Citations (Scopus)

Collaboration of RON and Epidermal Growth Factor Receptor in Human Bladder Carcinogenesis

Hsu, P. Y., Liu, H-S., Cheng, H-L., Tzai, T. S., Guo, H-R., Ho, C-L. & Chow, N-H., 2006 Nov 1, In : Journal of Urology. 176, 5, p. 2262-2267 6 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Carcinogenesis
Urinary Bladder
Urinary Bladder Neoplasms
rice bran saccharide
1 Citation (Scopus)
Plasma Cell Granuloma
Myofibroblasts
Urinary Bladder
Pediatrics
Cytokines
2005
104 Citations (Scopus)

Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder

Cheng, H-L., Liu, H-S., Lin, Y-J., Chen, H. H. W., Hsu, P. Y., Chang, T. Y., Ho, C-L., Tzai, T. S. & Chow, N-H., 2005 May 23, In : British Journal of Cancer. 92, 10, p. 1906-1914 9 p.

Research output: Contribution to journalArticle

Transitional Cell Carcinoma
Urinary Bladder
Urinary Bladder Neoplasms
Proto-Oncogene Proteins c-met
RON protein
13 Citations (Scopus)
Urothelium
Cytokines
Interleukin-5
Urinary Tract
Eosinophils
97 Citations (Scopus)

The novel targets for anti-angiogenesis of genistein on human cancer cells

Su, S. J., Yeh, T-M., Chuang, W-J., Ho, C-L., Chang, K. L., Cheng, H. L., Liu, H-S., Cheng, H-L., Hsu, P. Y. & Chow, N-H., 2005 Jan 15, In : Biochemical Pharmacology. 69, 2, p. 307-318 12 p.

Research output: Contribution to journalArticle

Isoflavones
Genistein
Angiogenesis Inhibitors
Cells
Angiostatins
2004
17 Citations (Scopus)
Pentetic Acid
Kidney
Creatinine
Transforming Growth Factors
Apoptosis
3 Citations (Scopus)

Inflammatory pseudotumor of the bladder: A rare cause of hematuria with impending shock in a child

Hsieh, Y. J., Lin, K. Y., Cheng, H-L., Chen, T. J. & Chiou, Y-Y., 2004 Nov 1, In : Acta Paediatrica Taiwanica. 45, 6, p. 350-353 4 p.

Research output: Contribution to journalArticle

Plasma Cell Granuloma
Hematuria
Shock
Urinary Bladder
Cystoscopy
2003
19 Citations (Scopus)

Clinical significance of allelotype profiling for urothelial carcinoma

Tzai, T. S., Chen, H. H. W., Chan, S-H., Ho, C-L., Tsai, Y-S., Cheng, H-L., Dai, Y. C., Lin, J. S. N., Yang, W-H. & Chow, N-H., 2003 Aug 1, In : Urology. 62, 2, p. 378-384 7 p.

Research output: Contribution to journalArticle

Loss of Heterozygosity
Carcinoma
Carcinogenesis
Chromosomes
Survival
4 Citations (Scopus)

Interstitial Laser Photocoagulation for Treatment of Benign Prostatic Hypertrophy: Outcomes and Cost Effectiveness

Tsui, K. H., Chang, P. L., Chang, S. S. C. & Cheng, H-L., 2003 Nov 1, In : Chang Gung medical journal. 26, 11, p. 799-806 8 p.

Research output: Contribution to journalArticle

Laser Coagulation
Light Coagulation
Prostatic Hyperplasia
Cost-Benefit Analysis
Lasers
19 Citations (Scopus)

Prognostic values of p53 and HER-2/neu coexpression in invasive bladder cancer in Taiwan

Tsai, Y. S., Tzai, T. S., Chow, N. H., Yang, W. H., Tong, Y. C., Lin, J. S. N., Chang, C. C., Cheng, H. L. & Lin, Y. M., 2003 Oct 9, In : Urologia Internationalis. 71, 3, p. 262-270 9 p.

Research output: Contribution to journalArticle

Taiwan
Urinary Bladder Neoplasms
Neoplasms
Disease-Free Survival
Staining and Labeling
54 Citations (Scopus)

Signaling through P13K/AKT mediates stretch and PDGF-BBdependent DNA synthesis in bladder smooth muscle cells

Adam, R. M., Roth, J. A., Cheng, H-L., Rice, D. C., Khoury, J., Bauer, S. B., Peters, C. A. & Freeman, M. R., 2003 Jun 1, In : Journal of Urology. 169, 6, p. 2388-2393 6 p.

Research output: Contribution to journalArticle

Smooth Muscle Myocytes
Urinary Bladder
DNA
Myofibroblasts
1-Phosphatidylinositol 4-Kinase
2002
67 Citations (Scopus)
Transitional Cell Carcinoma
Urinary Bladder
Urinary Bladder Neoplasms
Neoplasms
Proto-Oncogenes
6 Citations (Scopus)

Spontaneous pyeloduodenal fistula: An unusual presentation in advanced renal transitional cell carcinoma

Chen, C. H., Cheng, H-L., Tong, Y-C. & Pan, C. C., 2002 Jan 1, In : Urology. 60, 2, 1 p.

Research output: Contribution to journalArticle

Transitional Cell Carcinoma
Renal Cell Carcinoma
Fistula
Kidney Calculi
Chronic Renal Insufficiency
2001
10 Citations (Scopus)

Role of β2-microglobulinuria and microalbuminuria in pediatric febrile urinary tract infection

Chiou, Y-Y., Chiu, N-T., Chen, M. J. & Cheng, H-L., 2001 May 7, In : Acta Paediatrica Taiwanica. 42, 2, p. 84-89 6 p.

Research output: Contribution to journalArticle

Urinary Tract Infections
Creatinine
Fever
Pediatrics
Technetium Tc 99m Dimercaptosuccinic Acid
16 Citations (Scopus)

Transurethral microwave thermotherapy for symptomatic benign prostatic hyperplasia: Long-term durability with Prostcare

Tsai, Y-S., Lin, J. S. N., Tong, Y-C., Tzai, T. S., Yang, W-H., Chang, C. C., Cheng, H-L., Lin, Y. & Jou, Y. C., 2001 Aug 6, In : European Urology. 39, 6, p. 688-694 7 p.

Research output: Contribution to journalArticle

Transurethral Resection of Prostate
Prostatic Hyperplasia
Retreatment
Therapeutics
Erectile Dysfunction
2000
12 Citations (Scopus)

The clinical value of p21(WAF1/CIP1) expression in superficial bladder cancer

Chow, N-H., Tzai, T. S., Cheng, H-L., Liu, H-S., Chan, S-H. & Tong, Y-C., 2000 Jan 1, In : Anticancer Research. 20, 2 B, p. 1173-1176 4 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Neoplasms
Survival
p53 Genes
Disease Progression
65 Citations (Scopus)

Transitional cell carcinoma in dialysis patients

Ou, J-H., Pan, C. C., Lin, J. S. N., Tzai, T. S., Yang, W-H., Chang, C. C., Cheng, H-L., Lin, Y. & Tong, Y-C., 2000 Jan 1, In : European Urology. 37, 1, p. 90-94 5 p.

Research output: Contribution to journalArticle

Transitional Cell Carcinoma
Dialysis
Urologic Neoplasms
Hematuria
Incidence
2 Citations (Scopus)

Transurethral microwave thermotherapy for symptomatic benign prostatic hyperplasia: Short-term experience with prostcare

Tsai, Y-S., Lin, J. S. N., Tong, Y-C., Tzai, T. S., Yang, W-H., Chang, C. C., Cheng, H-L., Lin, Y. & Jou, Y. C., 2000 Jan 1, In : Urologia Internationalis. 65, 2, p. 89-94 6 p.

Research output: Contribution to journalArticle

Transurethral Resection of Prostate
Prostatic Hyperplasia
Pain
Ejaculation
Urination
1999
36 Citations (Scopus)

Expression of vascular endothelial growth factor in primary superficial bladder cancer

Chow, N-H., Liu, H-S., Chan, S-H., Cheng, H-L. & Tzai, T. S., 1999, In : Anticancer Research. 19, 5 C, p. 4593-4597 5 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Vascular Endothelial Growth Factor A
Neoplasms
Urothelium
Mucous Membrane
9 Citations (Scopus)

Retroperitoneal plasmacytoma associated with hyperamylasemia

Tsai, Y-S., Cheng, H-L., Lin, J. S. N., Tong, Y-C. & Chang, K-C., 1999 Jan 1, In : Journal of Urology. 162, 5, p. 1681-1682 2 p.

Research output: Contribution to journalArticle

Hyperamylasemia
Plasmacytoma
Amylases
Tumor Biomarkers
Nephrectomy
1997
12 Citations (Scopus)

Prognostic significance of proliferating cell nuclear antigen expression in transitional cell carcinoma of the upper urinary tract

Cheng, H-L., Chow, N-H., Tzai, T. S., Tong, Y-C., Lin, J. S. N., Chan, S-H., Yang, W-H., Chang, C. C. & Lin, Y., 1997 Sep 3, In : Anticancer Research. 17, 4 A, p. 2789-2793 5 p.

Research output: Contribution to journalArticle

Transitional Cell Carcinoma
Proliferating Cell Nuclear Antigen
Urinary Tract
Neoplasms
Survival
91 Citations (Scopus)

Significance of urinary epidermal growth factor and its receptor expression in human bladder cancer

Chow, N-H., Liu, H-S., Lee, E. I. C., Chang, C-J., Chan, S-H., Cheng, H-L., Tzai, T. S. & Lin, J. S. N., 1997 Dec 1, In : Anticancer Research. 17, 2B, p. 1293-1296 4 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Urinary Bladder Neoplasms
Epidermal Growth Factor
Urine
Neoplasms
1996
6 Citations (Scopus)

Idiopathic infected hydrocele in infants: A case report and review

Yang, Y., Liu, C-C., Lin, Y-J., Yao, W-J. & Cheng, H-L., 1996 Jun 28, In : Pediatric Infectious Disease Journal. 15, 6, p. 545-546 2 p.

Research output: Contribution to journalArticle

Testicular Hydrocele
Doppler Color Ultrasonography
Staphylococcal Infections
Escherichia coli Infections
Bacterial Infections
54 Citations (Scopus)

Prognostic factors of primary transitional cell carcinoma of the upper urinary tract

Lee, S. H., Lin, J. S. N., Tzai, T. S., Chow, N-H., Tong, Y-C., Yang, W-H., Chang, C. C. & Cheng, H-L., 1996 Jan 1, In : European Urology. 29, 3, p. 266-271 6 p.

Research output: Contribution to journalArticle

Transitional Cell Carcinoma
Urinary Tract
Neoplasms
Ploidies
DNA
1995
15 Citations (Scopus)

Significance of urinary tissue polypeptide specific antigen (TPS). Determination in patients with urothelial carcinoma

Yao, W-J., Chang, C-J., Chan, S-H., Chow, N-H., Cheng, H-L., Tzai, T. S. & Lin, S. N., 1995 Dec 1, In : Anticancer research. 15, 6 B, p. 2819-2823 5 p.

Research output: Contribution to journalArticle

Urine
Carcinoma
Transitional Cell Carcinoma
Urologic Diseases
tissue polypeptide specific antigen
1994

Near-diploid transitional cell carcinoma: A preliminary report

Chow, N-H., Tzai, T. S., Lin, S. N., Su, W-C. & Cheng, H-L., 1994 Dec 1, In : International Urology and Nephrology. 26, 4, p. 423-430 8 p.

Research output: Contribution to journalArticle

Transitional Cell Carcinoma
Diploidy
Neoplasms
DNA
Aneuploidy
16 Citations (Scopus)

Urinary cytodiagnosis: Can it have a different prognostic implication than a diagnostic test?

Chow, N-H., Tzai, T. S., Cheng, H-L., Chan, S-H. & Lin, J. S. N., 1994 Jan 1, In : Urologia Internationalis. 53, 1, p. 18-23 6 p.

Research output: Contribution to journalArticle

Cytodiagnosis
Routine Diagnostic Tests
Cell Biology
Neoplasms
Transitional Cell Carcinoma