Hui-Ping Hsu

Associate Professor

  • 614 Citations
  • 14 h-Index
19992019
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Research Output 1999 2019

  • 614 Citations
  • 14 h-Index
  • 39 Article
  • 1 Review article
2019

Mutation of the PTCH1 gene predicts recurrence of breast cancer

Wang, C. Y., Chang, Y. C., Kuo, Y. L., Lee, K. T., Chen, P. S., Cheung, C. H. A., Chang, C. P., Phan, N. N., Shen, M. R. & Hsu, H. P., 2019 Nov 8, In : Scientific reports. 9, 1, 1 p., 16359.

Research output: Contribution to journalArticle

Open Access
Breast Neoplasms
Recurrence
Mutation
Genes
Computational Biology

Treatment of a patient with breast cancer and glucose 6-phosphate dehydrogenase deficiency: A case report

Chung, W-P., Hsu, Y. T., Chen, Y. P. & Hsu, H-P., 2019 Mar 1, In : Medicine. 98, 13, p. e14987

Research output: Contribution to journalArticle

Open Access
Glucosephosphate Dehydrogenase Deficiency
docetaxel
Breast Neoplasms
Hemolytic Anemia
Therapeutics
2018
1 Citation (Scopus)

Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation

Weng, T. Y., Wu, H. F., Li, C. Y., Hung, Y. H., Chang, Y. W., Chen, Y. L., Hsu, H. P., Chen, Y. H., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2018 Dec 1, In : Scientific reports. 8, 1, 8216.

Research output: Contribution to journalArticle

Mutation
Neoplasms
B-Lymphocytes
Lung
Cytokines
1 Citation (Scopus)

Laparoscopic surgery for large left lateral liver tumors: safety and oncologic outcomes

Yang, T-H., Chen, J. L., Lin, Y-J., Chao, Y-J., Shan, Y-S., Hsu, H-P., Su, C-M., Chou, C. C. & Yen, Y-T., 2018 Oct 1, In : Surgical Endoscopy. 32, 10, p. 4314-4320 7 p.

Research output: Contribution to journalArticle

Laparoscopy
Segmental Mastectomy
Safety
Liver
Neoplasms
2017
13 Citations (Scopus)

Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer

Shan, Y. S., Hsu, H. P., Lai, M. D., Hung, Y. H., Wang, C. Y., Yen, M. C. & Chen, Y. L., 2017 Jan 1, In : Oncology Letters. 14, 4, p. 4517-4526 10 p.

Research output: Contribution to journalArticle

Cyclin D1
Stomach Neoplasms
Cyclin D2
Stomach
Cyclin D

Invasive lobular carcinoma of breast with synchronous colon metastasis

Loh, Z-J., Lee, K-T., Chung, W-P., Chen, W. C., Kuo, H-L., Chen, P. J., Lu, H-H. & Hsu, H-P., 2017 Mar 1, In : Formosan Journal of Surgery. 50, 2, p. 69-73 5 p.

Research output: Contribution to journalArticle

Lobular Carcinoma
Colon
Breast
Neoplasm Metastasis
Breast Neoplasms
11 Citations (Scopus)

Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling

Hsu, H. P., Lai, M. D., Lee, J. C., Yen, M. C., Weng, T. Y., Chen, W. C., Fang, J. H. & Chen, Y. L., 2017 Dec 1, In : Scientific reports. 7, 1, 5823.

Research output: Contribution to journalArticle

Mucin-2
Colonic Neoplasms
Interleukin-6
Neoplasm Metastasis
Checkpoint Kinase 2
3 Citations (Scopus)

PSMB5 plays a dual role in cancer development and immunosuppression

Wang, C. Y., Li, C. Y., Hsu, H. P., Cho, C. Y., Yen, M. C., Weng, T. Y., Chen, W. C., Hung, Y. H., Lee, K. T., Hung, J. H., Chen, Y. L. & Lai, M. D., 2017 Jan 1, In : American Journal of Cancer Research. 7, 11, p. 2103-2120 18 p.

Research output: Contribution to journalArticle

Immunosuppression
Neoplasms
Proteasome Endopeptidase Complex
Computational Biology
Macrophages
6 Citations (Scopus)

Silencing of argininosuccinate lyase inhibits colorectal cancer formation

Huang, H. L., Chen, W. C., Hsu, H. P., Cho, C. Y., Hung, Y. H., Wang, C. Y. & Lai, M. D., 2017 Jan, In : Oncology Reports. 37, 1, p. 163-170 8 p.

Research output: Contribution to journalArticle

Argininosuccinate Lyase
Colorectal Neoplasms
Colonic Neoplasms
Nitric Oxide
Small Interfering RNA

Skin Delivery of Clec4a Small Hairpin RNA Elicited an Effective Antitumor Response by Enhancing CD8+ Immunity In Vivo

Weng, T. Y., Li, C. J., Li, C. Y., Hung, Y. H., Yen, M. C., Chang, Y. W., Chen, Y-H., Chen, Y. L., Hsu, H-P., Chang, J-Y. & Lai, M-D., 2017 Dec 1, In : Molecular Therapy - Nucleic Acids. 9, p. 419-427 9 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Immunity
Skin
Neoplasms
DNA Vaccines
2016
3 Citations (Scopus)

A novel application of E1A in combination therapy with EGFR- TKI treatment in breast cancer

Su, C. M., Chang, T. Y., Hsu, H. P., Lai, H. H., Li, J. N., Lyu, Y. J., Kuo, K. T., Huang, M. T., Su, J. L. & Chen, P. S., 2016 Jan 1, In : Oncotarget. 7, 39, p. 63924-63936 13 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Breast Neoplasms
Therapeutics
Genetic Therapy
Protein-Tyrosine Kinases
10 Citations (Scopus)

Cancer stem cell marker CD90 inhibits ovarian cancer formation via β3 integrin

Chen, W. C., Hsu, H. P., Li, C. Y., Yang, Y. J., Hung, Y. H., Cho, C. Y., Wang, C. Y., Weng, T. Y. & Lai, M. D., 2016 Nov, In : International Journal of Oncology. 49, 5, p. 1881-1889 9 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Integrins
Ovarian Neoplasms
Growth
Anoikis
7 Citations (Scopus)

Membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia

Chen, M. C., Chen, Y. L., Wang, T. W., Hsu, H. P. & Lai, M. D., 2016 Oct, In : Oncology Reports. 36, 4, p. 1997-2008 12 p.

Research output: Contribution to journalArticle

Hyperbilirubinemia
Bile Acids and Salts
Adenocarcinoma
Membranes
GTP-Binding Proteins
10 Citations (Scopus)

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

Cho, C. Y., Lee, K. T., Chen, W. C., Wang, C. Y., Chang, Y. S., Huang, H. L., Hsu, H. P., Yen, M. C., Lai, M. Z. & Lai, M. D., 2016 Mar 22, In : Oncotarget. 7, 12, p. 14586-14604 19 p.

Research output: Contribution to journalArticle

Phosphotransferases
Breast Neoplasms
Proline
Growth
Down-Regulation
2015
10 Citations (Scopus)

Argininosuccinate lyase is a potential therapeutic target in breast cancer

Huang, H. L., Chen, W. C., Hsu, H. P., Cho, C. Y., Hung, Y. H., Wang, C. Y. & Lai, M. D., 2015 Dec 1, In : Oncology Reports. 34, 6, p. 3131-3139 9 p.

Research output: Contribution to journalArticle

Argininosuccinate Lyase
Breast Neoplasms
Cyclin A2
Small Interfering RNA
Autophagy
16 Citations (Scopus)

Argininosuccinate synthetase 1 suppression and arginine restriction inhibit cell migration in gastric cancer cell lines

Shan, Y-S., Hsu, H-P., Lai, M-D., Yen, M. C., Chen, W. C., Fang, J. H., Weng, T. Y. & Chen, Y. L., 2015 Apr 30, In : Scientific reports. 5, 9783.

Research output: Contribution to journalArticle

Argininosuccinate Synthase
Stomach Neoplasms
Cell Movement
Arginine
Cell Line
8 Citations (Scopus)
Protein Isoforms
Adenocarcinoma
Recurrence
Neoplasms
Reverse Transcription
Thrombophilia
Factor VIII
Thromboembolism
Thrombosis
Atherosclerosis
15 Citations (Scopus)

Increased expression of argininosuccinate synthetase protein predicts poor prognosis in human gastric cancer

Shan, Y-S., Hsu, H-P., Lai, M-D., Yen, M. C., Luo, Y. P. & Chen, Y. L., 2015 Jan 1, In : Oncology Reports. 33, 1, p. 49-57 9 p.

Research output: Contribution to journalArticle

Argininosuccinate Synthase
Stomach Neoplasms
Neoplasms
Proteins
Neoplasm Staging
7 Citations (Scopus)
Nestin
Adenocarcinoma
Neoplasm Metastasis
Cyclin-Dependent Kinase 5
Neoplasms
16 Citations (Scopus)

Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer

Chen, W. C., Chang, Y. S., Hsu, H. P., Yen, M. C., Huang, H. L., Cho, C. Y., Wang, C. Y., Weng, T. Y., Lai, P. T., Chen, C. S., Lin, Y. J. & Lai, M. D., 2015 Jan 1, In : Oncotarget. 6, 40, p. 42923-42937 15 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Liver Neoplasms
Integrins
Neoplastic Stem Cells
Neoplasms
2014
11 Citations (Scopus)

Fatty acid metabolic enzyme acyl-CoA thioesterase 8 promotes the development of hepatocellular carcinoma

Hung, Y. U. H., Chan, Y. I. S., Chang, Y. S., Lee, K. T., Hsu, H. P., Yen, M. C., Chen, W. C., Wang, C. Y. & Lai, M. D., 2014 Jan 1, In : Oncology Reports. 31, 6, p. 2797-2803 7 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Hepatocellular Carcinoma
Fatty Acids
Enzymes
Nonesterified Fatty Acids
8 Citations (Scopus)
gemcitabine
Neoadjuvant Therapy
Pancreatic Neoplasms
Survival
Head and Neck Neoplasms
13 Citations (Scopus)

Suppression of mucin 2 promotes interleukin-6 secretion and tumor growth in an orthotopic immune-competent colon cancer animal model

Shan, Y-S., Hsu, H-P., Lai, M-D., Yen, M. C., Fang, J. H., Weng, T. Y. & Chen, Y. L., 2014 Dec 1, In : Oncology Reports. 32, 6, p. 2335-2342 8 p.

Research output: Contribution to journalArticle

Mucin-2
Colonic Neoplasms
Interleukin-6
Animal Models
Growth
2013
16 Citations (Scopus)

Attenuation of argininosuccinate lyase inhibits cancer growth via cyclin A2 and nitric oxide

Huang, H. L., Hsu, H-P., Shiesh, S-C., Chang, Y. S., Chen, W. C., Cho, C. Y., Teng, C. F., Su, I. J., Hung, W. C. & Lai, M-D., 2013 Jan 1, In : Molecular Cancer Therapeutics. 12, 11, p. 2505-2516 12 p.

Research output: Contribution to journalArticle

Cyclin A2
Argininosuccinate Lyase
Nitric Oxide
Growth
Small Interfering RNA
9 Citations (Scopus)

Validation of Memorial Sloan-Kettering Cancer Center nomogram for prediction of non-sentinel lymph node metastasis in sentinel lymph node positive breast cancer patients an international comparison

Kuo, Y. L., Chen, W. C., Yao, W. J., Cheng, L., Hsu, H. P., Lai, H. W., Kuo, S. J., Chen, D. R. & Chang, T. W., 2013 Jun 11, In : International Journal of Surgery. 11, 7, p. 538-543 6 p.

Research output: Contribution to journalArticle

Nomograms
Lymph Nodes
Breast Neoplasms
Neoplasm Metastasis
Lymph Node Excision
2011
11 Citations (Scopus)

Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules

Shan, Y-S., Fang, J. H., Lai, M-D., Yen, M. C., Lin, P. W., Hsu, H-P., Lin, C. Y. & Chen, Y. L., 2011 Oct 1, In : Molecular Carcinogenesis. 50, 10, p. 739-750 12 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Stomach
Animal Models
Carcinoma
Butyric Acid
2010
13 Citations (Scopus)

Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy

Lu, T. L., Huang, G. J., Wang, H. J., Chen, J. L., Hsu, H. P. & Lu, T. J., 2010 Jul 1, In : Biochemical and Biophysical Research Communications. 398, 1, p. 26-31 6 p.

Research output: Contribution to journalArticle

HSC70 Heat-Shock Proteins
Autophagy
Down-Regulation
Lysosome-Associated Membrane Glycoproteins
Proteasome Endopeptidase Complex
27 Citations (Scopus)

Loss of E-Cadherin and β-Catenin is correlated with poor prognosis of ampullary neoplasms

Hsu, H-P., Shan, Y-S., Jin, Y. T., Lai, M-D. & Lin, P. W., 2010 Apr 1, In : Journal of Surgical Oncology. 101, 5, p. 356-362 7 p.

Research output: Contribution to journalArticle

Catenins
Cadherins
Neoplasms
Recurrence
Staining and Labeling
17 Citations (Scopus)

Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival

Hsu, H-P., Shan, Y-S., Lai, M-D. & Lin, P. W., 2010 Jul 15, In : Cancer Biology and Therapy. 10, 2, p. 144-154 11 p.

Research output: Contribution to journalArticle

Osteopontin
Macrophages
Survival
Neoplasms
Macrophage Migration-Inhibitory Factors
14 Citations (Scopus)

Puerperal mastitis requiring hospitalization during a nine-year period

Lee, I. W., Kang, L., Hsu, H-P., Kuo, P-L. & Chang, C-M., 2010 Jan 1, In : American Journal of Obstetrics and Gynecology. 203, 4, p. 332.e1-332.e6

Research output: Contribution to journalArticle

Mastitis
Hospitalization
Oxacillin
Drainage
Breast Feeding
2008
1 Citation (Scopus)

Evaluation of the stability and safety of Venolipid MCT/LCT 20% administered by an all-in-one system in patients after major gastrointestinal surgery

Shan, Y-S., Huang, S. F., Wu, Y. H., Kao, A. W., Hsu, H-P. & Lin, P. W., 2008 Aug 1, In : e-SPEN. 3, 4

Research output: Contribution to journalArticle

Triglycerides
Safety
Particle Size
Flocculation
Glucose
2007
55 Citations (Scopus)

Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer

Hsu, H-P., Yang, T. M., Hsieh, Y. H., Shan, Y-S. & Lin, P. W., 2007 Jan 1, In : Annals of Surgical Oncology. 14, 1, p. 50-60 11 p.

Research output: Contribution to journalArticle

Pancreaticoduodenectomy
Neoplasm Metastasis
Recurrence
Lymph Nodes
Neoplasms
21 Citations (Scopus)

Predictors of recurrence after pancreaticoduodenectomy in ampullary cancer: Comparison between non-, early and late recurrence

Hsu, H-P., Shan, Y-S., Hsieh, Y. H., Yang, T. M. & Lin, P. W., 2007 Jan 1, In : Journal of the Formosan Medical Association. 106, 6, p. 432-443 12 p.

Research output: Contribution to journalArticle

Pancreaticoduodenectomy
Recurrence
Neoplasms
Lymph Nodes
Municipal Hospitals
62 Citations (Scopus)

The pylorus: Take it or leave it? Systematic review and meta-analysis of pylorus-preserving versus standard whipple pancreaticoduodenectomy for pancreatic or periampullary cancer

Karanicolas, P. J., Davies, E., Kunz, R., Briel, M., Koka, H. P., Payne, D. M., Smith, S. E., Hsu, H-P., Lin, P. W., Bloechle, C., Paquet, K. J. & Guyatt, G. H., 2007 Jun 1, In : Annals of Surgical Oncology. 14, 6, p. 1825-1834 10 p.

Research output: Contribution to journalReview article

Pancreaticoduodenectomy
Pylorus
Meta-Analysis
Confidence Intervals
Neoplasms
2006
15 Citations (Scopus)
APACHE
Therapeutics
Mesenteric Ischemia
Mortality
2003
29 Citations (Scopus)

Significance of intraoperative peritoneal culture of fungus in perforated peptic ulcer

Shan, Y-S., Hsu, H-P., Hsieh, Y. H., Shih, C. W., Lee, J-C. & Lin, P. W., 2003 Oct 1, In : British Journal of Surgery. 90, 10, p. 1215-1219 5 p.

Research output: Contribution to journalArticle

Ascitic Fluid
Peritonitis
Peptic Ulcer
Fungi
Surgical Wound Infection
2001
9 Citations (Scopus)

Inhibition of the increased permeability of blood-brain barrier in escherichia coli-induced meningitis by carboxyfullerene

Tsao, N., Wu, C. M., Hsu, H-P., Liu, C-C., Luh, T. Y., Chou, C. K. & Lei, H. Y., 2001 Jan 1, In : Fullerene Science and Technology. 9, 3, p. 307-320 14 p.

Research output: Contribution to journalArticle

meningitis
blood-brain barrier
Escherichia
Escherichia coli
permeability
122 Citations (Scopus)

Tumour necrosis factor-α causes an increase in blood-brain barrier permeability during sepsis

Tsao, N., Hsu, H-P., Wu, C. M., Liu, C-C. & Lei, H. Y., 2001 Jan 1, In : Journal of Medical Microbiology. 50, 9, p. 812-821 10 p.

Research output: Contribution to journalArticle

Blood-Brain Barrier
Permeability
Sepsis
Tumor Necrosis Factor-alpha
Streptococcus pneumoniae
1999
24 Citations (Scopus)
Encephalitis
Cyclooxygenase 2
Blood-Brain Barrier
Escherichia coli
Brain