Research Output per year
Research Output
2020
The promyelocytic leukemia protein isoform PML1 is an oncoprotein and a direct target of the antioxidant sulforaphane (SFN)
Alhazmi, N., Pai, C. P., Albaqami, A., Wang, H., Zhao, X., Chen, M., Hu, P., Guo, S., Starost, K., Hajihassani, O., Miyagi, M. & Kao, H. Y., 2020 Aug 1, In : Biochimica et biophysica acta. Molecular cell research. 1867, 8, 1 p.Research output: Contribution to journal › Article
Open Access
The tumor suppressor TGFBR3 blocks lymph node metastasis in head and neck cancer
Fang, W. Y., Kuo, Y. Z., Chang, J. Y., Hsiao, J. R., Kao, H. Y., Tsai, S. T. & Wu, L. W., 2020 Jun, In : Cancers. 12, 6, 1375.Research output: Contribution to journal › Article
Open Access
2019
Cancer-associated fibroblast-derived interleukin-1β activates protumor C-C motif chemokine ligand 22 signaling in head and neck cancer
Huang, Y. H., Chang, C. Y., Kuo, Y. Z., Fang, W. Y., Kao, H. Y., Tsai, S. T. & Wu, L. W., 2019 Sep 1, In : Cancer Science. 110, 9, p. 2783-2793 11 p.Research output: Contribution to journal › Article
Open Access
4
Citations
(Scopus)
2018
ACTN4 regulates the stability of RIPK1 in melanoma
Zhang, Y. Y., Tabataba, H., Liu, X. Y., Wang, J. Y., Yan, X. G., Farrelly, M., Jiang, C. C., Guo, S. T., Liu, T., Kao, H. Y., Thorne, R. F., Zhang, X. D. & Jin, L., 2018 Jul 19, In : Oncogene. 37, 29, p. 4033-4045 13 p.Research output: Contribution to journal › Article
7
Citations
(Scopus)
Correction: PML: Regulation and multifaceted function beyond tumor suppression [Cell Biosci., 8 (2018) (5)] DOI: 10.1186/s13578-018-0204-8
Hsu, K. S. & Kao, H. Y., 2018 Mar 6, In : Cell and Bioscience. 8, 1, 18.Research output: Contribution to journal › Comment/debate
Open Access
Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains
Huang, W., Peng, Y., Kiselar, J., Zhao, X., Albaqami, A., Mendez, D., Chen, Y., Chakravarthy, S., Gupta, S., Ralston, C., Kao, H. Y., Chance, M. R. & Yang, S., 2018 Dec 1, In : Nature communications. 9, 1, 3520.Research output: Contribution to journal › Article
Open Access
14
Citations
(Scopus)
PML: Regulation and multifaceted function beyond tumor suppression
Hsu, K. S. & Kao, H. Y., 2018 Jan 25, In : Cell and Bioscience. 8, 1, 5.Research output: Contribution to journal › Review article
Open Access
14
Citations
(Scopus)
The p53-S100A2 Positive Feedback Loop Negatively Regulates Epithelialization in Cutaneous Wound Healing
Pan, S. C., Li, C. Y., Kuo, C. Y., Kuo, Y. Z., Fang, W. Y., Huang, Y. H., Hsieh, T. C., Kao, H. Y., Kuo, Y., Kang, Y. R., Tsai, W. C., Tsai, S. T. & Wu, L. W., 2018 Dec 1, In : Scientific reports. 8, 1, 5458.Research output: Contribution to journal › Article
3
Citations
(Scopus)
2017
Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon α-mediated inhibition of angiogenesis
Hsu, K. S., Zhao, X., Cheng, X., Guan, D., Mahabeleshwar, G. H., Liu, Y., Borden, E., Jain, M. K. & Kao, H. Y., 2017 Jun 16, In : Journal of Biological Chemistry. 292, 24, p. 10048-10060 13 p.Research output: Contribution to journal › Article
Open Access
6
Citations
(Scopus)
α actinin 4 (ACTN4) regulates glucocorticoid receptor-mediated transactivation and transrepression in podocytes
Zhao, X., Khurana, S., Charkraborty, S., Tian, Y., Sedor, J. R., Bruggman, L. A. & Kao, H. Y., 2017 Feb 3, In : Journal of Biological Chemistry. 292, 5, p. 1637-1647 11 p.Research output: Contribution to journal › Article
Open Access
13
Citations
(Scopus)
2016
A signaling network controlling androgenic repression of c-Fos protein in prostate adenocarcinoma cells
Shankar, E., Song, K., Corum, S. L., Bane, K. L., Wang, H., Kao, H. Y. & Danielpour, D., 2016 Mar 11, In : Journal of Biological Chemistry. 291, 11, p. 5512-5526 15 p.Research output: Contribution to journal › Article
Open Access
9
Citations
(Scopus)
Translational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs
Hsu, K. S., Guan, B. J., Cheng, X., Guan, D., Lam, M., Hatzoglou, M. & Kao, H. Y., 2016 Mar 1, In : Cell Death and Differentiation. 23, 3, p. 469-483 15 p.Research output: Contribution to journal › Article
Open Access
14
Citations
(Scopus)
2015
Erratum: The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein(Oncogene(2015)32(3819-3828)10.1038/onc.2012.406)
Guan, D., Factor, D., Liu, Y., Wang, Z. & Kao, H. Y., 2015 Oct 1, In : Oncogene. 34, 40, 1 p.Research output: Contribution to journal › Comment/debate
1
Citation
(Scopus)
Novel vitamin D receptor mutations in hereditary vitamin D resistant rickets in Chinese
Lim, L. M., Zhao, X., Chao, M. C., Chang, J. M., Chang, W. C., Kao, H-Y., Hwang, D. Y. & Chen, H. C., 2015 Sep 30, In : PloS one. 10, 9, e0138152.Research output: Contribution to journal › Article
Open Access
6
Citations
(Scopus)
The actinin family proteins: Biological function and clinical implications
Kao, H. Y., 2015 Aug 25, In : Cell and Bioscience. 5, 1, 48.Research output: Contribution to journal › Editorial
Open Access
4
Citations
(Scopus)
The function, regulation and therapeutic implications of the tumor suppressor protein, PML
Guan, D. & Kao, H. Y., 2015 Nov 4, In : Cell and Bioscience. 5, 1, 60.Research output: Contribution to journal › Review article
Open Access
30
Citations
(Scopus)
α-actinin 4 potentiates nuclear factor κ-light-chain-enhancer of activated B-cell (NF-κB) activity in podocytes independent of its cytoplasmic actin binding function
Zhao, X., Hsu, K. S., Lim, J. H., Bruggeman, L. A. & Kao, H. Y., 2015 Jan 2, In : Journal of Biological Chemistry. 290, 1, p. 338-349 12 p.Research output: Contribution to journal › Article
Open Access
21
Citations
(Scopus)
2014
Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity
Guo, S., Cheng, X., Lim, J. H., Liu, Y. & Kao, H. Y., 2014 Jan 1, In : Molecular Biology of the Cell. 25, 16, p. 2485-2498 14 p.Research output: Contribution to journal › Article
12
Citations
(Scopus)
Deacetylation of the tumor suppressor protein PML regulates hydrogen peroxide-Induced cell death
Guan, D., Lim, J. H., Peng, L., Liu, Y., Lam, M., Seto, E. & Kao, H. Y., 2014 Jul, In : Cell Death and Disease. 5, 7, e1340.Research output: Contribution to journal › Article
Open Access
20
Citations
(Scopus)
2013
Ablation of promyelocytic leukemia protein (PML) re-patterns energy balance and protects mice from obesity induced by a western diet
Cheng, X., Guo, S., Liu, Y., Chu, H., Hakimi, P., Berger, N. A., Hanson, R. W. & Kao, H. Y., 2013 Oct 11, In : Journal of Biological Chemistry. 288, 41, p. 29746-29759 14 p.Research output: Contribution to journal › Article
Open Access
15
Citations
(Scopus)
Alpha-Actinin 4 and Tumorigenesis of Breast Cancer
Hsu, K. S. & Kao, H. Y., 2013, Vitamins and Hormones. Academic Press Inc., p. 323-351 29 p. (Vitamins and Hormones; vol. 93).Research output: Chapter in Book/Report/Conference proceeding › Chapter
27
Citations
(Scopus)
Correction: Microarray analyses of glucocorticoid and vitamin D3 target genes in differentiating cultured human podocytes (PLoS ONE)
Cheng, X., Zhao, X., Khurana, S., Bruggeman, L. A. & Kao, H. Y., 2013 Jun 21, In : PloS one. 8, 6Research output: Contribution to journal › Comment/debate
Open Access
3
Citations
(Scopus)
Microarray Analyses of Glucocorticoid and Vitamin D3 Target Genes in Differentiating Cultured Human Podocytes
Cheng, X., Zhao, X., Khurana, S., Bruggeman, L. A. & Kao, H. Y., 2013 Apr 4, In : PloS one. 8, 4, e60213.Research output: Contribution to journal › Article
Open Access
8
Citations
(Scopus)
Monoubiquitination of filamin B regulates vascular endothelial growth factor-mediated trafficking of histone deacetylase 7
Su, Y. T., Gao, C., Liu, Y., Guo, S., Wang, A., Wang, B., Erdjument-Bromage, H., Miyagi, M., Tempst, P. & Kao, H. Y., 2013 Apr 1, In : Molecular and Cellular Biology. 33, 8, p. 1546-1560 15 p.Research output: Contribution to journal › Article
12
Citations
(Scopus)
Post-translational modifications of PML: Consequences and implications
Cheng, X. & Kao, H. Y., 2013 Dec 24, In : Frontiers in Oncology. 2 JAN, Article 00210.Research output: Contribution to journal › Review article
Open Access
30
Citations
(Scopus)
The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein
Guan, D., Factor, D., Liu, Y., Wang, Z. & Kao, H. Y., 2013 Aug 15, In : Oncogene. 32, 33, p. 3819-3828 10 p.Research output: Contribution to journal › Article
Open Access
43
Citations
(Scopus)
β-transducin repeat-containing protein 1 (β-TrCP1)-mediated silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) protein degradation promotes tumor necrosis factor α (TNFα)-induced inflammatory gene expression
Hsu, K. S. & Kao, H. Y., 2013 Aug 30, In : Journal of Biological Chemistry. 288, 35, p. 25375-25386 12 p.Research output: Contribution to journal › Article
Open Access
4
Citations
(Scopus)
2012
Acetylation of retinal histones in diabetes increases inflammatory proteins: Effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC)
Kadiyala, C. S. R., Zheng, L., Du, Y., Yohannes, E., Kao, H. Y., Miyagi, M. & Kern, T. S., 2012 Jul 27, In : Journal of Biological Chemistry. 287, 31, p. 25869-25880 12 p.Research output: Contribution to journal › Article
Open Access
72
Citations
(Scopus)
Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors
Khurana, S., Chakraborty, S., Lam, M., Liu, Y., Su, Y. T., Zhao, X., Saleem, M. A., Mathieson, P. W., Bruggeman, L. A. & Kao, H. Y., 2012 Apr 6, In : Journal of Biological Chemistry. 287, 15, p. 12027-12035 9 p.Research output: Contribution to journal › Article
Open Access
27
Citations
(Scopus)
Identification of a novel LXXLL motif in α-actinin 4-spliced isoform that is critical for its interaction with estrogen receptor α and co-activators
Khurana, S., Chakraborty, S., Zhao, X., Liu, Y., Guan, D., Lam, M., Huang, W., Yang, S. & Kao, H. Y., 2012 Oct 12, In : Journal of Biological Chemistry. 287, 42, p. 35418-35429 12 p.Research output: Contribution to journal › Article
Open Access
18
Citations
(Scopus)
Microarray analysis revealing common and distinct functions of promyelocytic leukemia protein (PML) and tumor necrosis factor alpha (TNFα) signaling in endothelial cells
Cheng, X. & Kao, H. Y., 2012 Sep 4, In : BMC genomics. 13, 1, 453.Research output: Contribution to journal › Article
Open Access
15
Citations
(Scopus)
Nuclear hormone receptors in podocytes
Khurana, S., Bruggeman, L. A. & Kao, H. Y., 2012 Sep 20, In : Cell and Bioscience. 2, 1, 33.Research output: Contribution to journal › Review article
Open Access
11
Citations
(Scopus)
Promyelocytic Leukemia Protein (PML) regulates endothelial cell network formation and migration in response to tumor necrosis factor α (TNFα) and interferon α (IFNα)
Cheng, X., Liu, Y., Chu, H. & Kao, H. Y., 2012 Jul 6, In : Journal of Biological Chemistry. 287, 28, p. 23356-23367 12 p.Research output: Contribution to journal › Article
Open Access
24
Citations
(Scopus)
2011
Mitogen-activated protein kinase extracellular signal-regulated kinase 2 phosphorylates and promotes Pin1 protein-dependent promyelocytic leukemia protein turnover
Lim, J. H., Liu, Y., Reineke, E. & Kao, H. Y., 2011 Dec 30, In : Journal of Biological Chemistry. 286, 52, p. 44403-44411 9 p.Research output: Contribution to journal › Article
Open Access
25
Citations
(Scopus)
The actin-binding protein, actinin alpha 4 (ACTN4), is a nuclear receptor coactivator that promotes proliferation of MCF-7 breast cancer cells
Khurana, S., Chakraborty, S., Cheng, X., Su, Y. T. & Kao, H. Y., 2011 Jan 21, In : Journal of Biological Chemistry. 286, 3, p. 1850-1859 10 p.Research output: Contribution to journal › Article
Open Access
52
Citations
(Scopus)
2010
DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination
Du, Z., Song, J., Wang, Y., Zhao, Y., Guda, K., Yang, S., Kao, H. Y., Xu, Y., Willis, J., Markowitz, S. D., Sedwick, D., Ewing, R. M. & Wang, Z., 2010 Nov 2, In : Science Signaling. 3, 146, ra80.Research output: Contribution to journal › Article
Open Access
180
Citations
(Scopus)
Histone deacetylase 7 (HDAC7) regulates myocyte migration and differentiation
Gao, C., Liu, Y., Lam, M. & Kao, H. Y., 2010 Oct 1, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1803, 10, p. 1186-1197 12 p.Research output: Contribution to journal › Article
Open Access
8
Citations
(Scopus)
Membrane permeable cyclic peptidyl inhibitors against human peptidylprolyl isomer ase pin1
Liu, T., Liu, Y., Kao, H. Y. & Pei, D., 2010 Mar 25, In : Journal of Medicinal Chemistry. 53, 6, p. 2494-2501 8 p.Research output: Contribution to journal › Article
49
Citations
(Scopus)
Promyelocytic leukemia protein controls cell migration in response to hydrogen peroxide and insulin-like growth factor-1
Reineke, E. L., Liu, Y. & Kao, H. Y., 2010 Mar 26, In : Journal of Biological Chemistry. 285, 13, p. 9485-9492 8 p.Research output: Contribution to journal › Article
Open Access
29
Citations
(Scopus)
2009
G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor α-mediated transcriptional regulation
Cheng, X. & Kao, H. Y., 2009 Dec 25, In : Journal of Biological Chemistry. 284, 52, p. 36395-36404 10 p.Research output: Contribution to journal › Article
Open Access
22
Citations
(Scopus)
New insights into the functions and regulation of the transcriptional corepressors SMRT and N-CoR
Stanya, K. J. & Kao, H. Y., 2009 Apr 21, In : Cell Division. 4, 7.Research output: Contribution to journal › Review article
Open Access
28
Citations
(Scopus)
PML: An emerging tumor suppressor and a target with therapeutic potential
Reineke, E. L. & Kao, H. Y., 2009 Jan 1, In : Cancer Therapy. 7, ISSUE A, p. 219-226 8 p.Research output: Contribution to journal › Review article
16
Citations
(Scopus)
Targeting promyelocytic leukemia protein: A means to regulating PML nuclear bodies
Reineke, E. L. & Kao, H. Y., 2009 Jan 1, In : International Journal of Biological Sciences. 5, 4, p. 366-376 11 p.Research output: Contribution to journal › Review article
Open Access
32
Citations
(Scopus)
2008
Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT
Stanya, K. J., Liu, Y., Means, A. R. & Kao, H. Y., 2008 Oct 6, In : Journal of Cell Biology. 183, 1, p. 49-61 13 p.Research output: Contribution to journal › Article
Open Access
46
Citations
(Scopus)
Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 ce11s
Reineke, E. L., Lam, M., Liu, Q., Liu, Y., Stanya, K. J., Chang, K. S., Means, A. R. & Kao, H. Y., 2008 Feb 1, In : Molecular and Cellular Biology. 28, 3, p. 997-1006 10 p.Research output: Contribution to journal › Article
Open Access
66
Citations
(Scopus)
Histone deacetylase 7 promotes PML sumoylation and is essential for PML nuclear body formation
Gao, C., Ho, C. C., Reineke, E., Lam, M., Cheng, X., Stanya, K. J., Liu, Y., Chakraborty, S., Shih, H. M. & Kao, H. Y., 2008 Sep 1, In : Molecular and Cellular Biology. 28, 18, p. 5658-5667 10 p.Research output: Contribution to journal › Article
Open Access
54
Citations
(Scopus)
Signal-dependent regulation of transcription by histone deacetylase 7 involves recruitment to promyelocytic leukemia protein nuclear bodies
Gao, C., Cheng, X., Lam, M., Liu, Y., Liu, Q., Chang, K. S. & Kao, H. Y., 2008 Jul 1, In : Molecular Biology of the Cell. 19, 7, p. 3020-3024 5 p.Research output: Contribution to journal › Article
29
Citations
(Scopus)
The Positive Transcription Elongation Factor b Is an Essential Cofactor for the Activation of Transcription by Myocyte Enhancer Factor 2
Nojima, M., Huang, Y., Tyagi, M., Kao, H. Y. & Fujinaga, K., 2008 Oct 3, In : Journal of Molecular Biology. 382, 2, p. 275-287 13 p.Research output: Contribution to journal › Article
20
Citations
(Scopus)
VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis
Chang, H. H., Bong, S. J., Kao, H. Y. & Jin, Z. G., 2008 Oct 1, In : Arteriosclerosis, thrombosis, and vascular biology. 28, 10, p. 1782-1788 7 p.Research output: Contribution to journal › Article
Open Access
65
Citations
(Scopus)
2007
Aberrant association of promyelocytic leukemia protein-retinoic acid receptor-α with coactivators contributes to its ability to regulate gene expression
Reineke, E. L., Liu, H., Lam, M., Liu, Y. & Kao, H. Y., 2007 Jun 22, In : Journal of Biological Chemistry. 282, 25, p. 18584-18596 13 p.Research output: Contribution to journal › Article
Open Access
8
Citations
(Scopus)