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Personal profile

Education

  • 國防醫學院醫學系學士

Research Interests

  • 癌症臨床試驗及抗癌藥物

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Neoplasms Medicine & Life Sciences
Cells Chemical Compounds
Tubulin Medicine & Life Sciences
oxaliplatin Medicine & Life Sciences
KB Cells Medicine & Life Sciences
Inhibitory Concentration 50 Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Head and Neck Neoplasms Medicine & Life Sciences

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Projects 2014 2018

Research Output 1989 2019

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J-Y. & Liou, J. P., 2019 Jan 15, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50

Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition (Org. Biomol. Chem. (2016) 14 (716-723))

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J-Y., Liou, J. P. & Lee, H. Y., 2018 Jan 1, In : Organic and Biomolecular Chemistry. 16, 25, 1 p.

Research output: Contribution to journalComment/debate

HSP90 Heat-Shock Proteins
Dione
Tubulin
Antineoplastic Agents
Emotions

Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation

Weng, T. Y., Wu, H. F., Li, C. Y., Hung, Y. H., Chang, Y. W., Chen, Y. L., Hsu, H-P., Chen, Y-H., Wang, C. Y., Chang, J-Y. & Lai, M-D., 2018 Dec 1, In : Scientific Reports. 8, 1, 8216.

Research output: Contribution to journalArticle

Mutation
Neoplasms
B-Lymphocytes
Lung
Cytokines

Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

Tsai, I. T., Kuo, C. C., Liou, J. P. & Chang, J-Y., 2018 Mar 28, In : Journal of Biomedical Science. 25, 1, 28.

Research output: Contribution to journalArticle

Phosphorylation
Epithelial-Mesenchymal Transition
Microtubules
Transforming Growth Factor beta
Assays

The interplay between oral microbiome, lifestyle factors and genetic polymorphisms in the risk of oral squamous cell carcinoma

Hsiao, J-R., Chang, C. C., Lee, W. T., Huang, C. C., Ou, C. Y., Tsai, S-T., Chen, K. C., Huang, J-S., Wang, D-Y., Lai, Y. H., Wu, Y-H., Hsueh, W. T., Wu, S. Y., Yen, C-J., Chang, J-Y., Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2018 May 28, In : Carcinogenesis. 39, 6, p. 778-787 10 p.

Research output: Contribution to journalArticle

Microbiota
Genetic Polymorphisms
Life Style
Squamous Cell Carcinoma
Oral Hygiene