If you made any changes in Pure these will be visible here soon.

Research Output 1989 2019

2019
3 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J-Y. & Liou, J. P., 2019 Jan 15, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
Open Access
Colorectal Neoplasms
Neoplasms
Therapeutics
Genome
Mutation
1 Citation (Scopus)

Laminin γ2-enriched extracellular vesicles of oral squamous cell carcinoma cells enhance in vitro lymphangiogenesis via integrin α3-dependent uptake by lymphatic endothelial cells

Wang, S. H., Liou, G. G., Liu, S. H., Chang, J. S., Hsiao, J-R., Yen, Y. C., Chen, Y. L., Wu, W. L., Chang, J-Y. & Chen, Y. W., 2019 Jun 1, In : International Journal of Cancer. 144, 11, p. 2795-2810 16 p.

Research output: Contribution to journalArticle

Lymphangiogenesis
Laminin
Integrins
Squamous Cell Carcinoma
Endothelial Cells

Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca2+ entry

Lin, H. H., Chen, S-J., Shen, M-R., Huang, Y. T., Hsieh, H. P., Lin, S. Y., Lin, C. C., Chang, W. S. W. & Chang, J-Y., 2019 Dec 1, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 12, 118517.

Research output: Contribution to journalArticle

cathepsin S
Cysteine Proteases
Cell Movement
Neoplasms
protease S

New Insights into Mechanisms of Cisplatin Resistance: From Tumor Cell to Microenvironment

Chen, S. H. & Chang, J-Y., 2019 Aug 24, In : International journal of molecular sciences. 20, 17

Research output: Contribution to journalReview article

Open Access
Cellular Microenvironment
Cisplatin
Tumors
tumors
Cells

Oral hygiene and the overall survival of head and neck cancer patients

Chang, C-C., Lee, W-T., Hsiao, J-R., Ou, C-Y., Huang, C-C., Tsai, S-T., Chen, K-C., Huang, J-S., Wang, D-Y., Lai, Y-H., Wu, Y-H., Hsueh, W-T., Wu, S-Y., Yen, C-J., Chang, J-Y., Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2019 Apr 1, In : Cancer medicine. 8, 4, p. 1854-1864 11 p.

Research output: Contribution to journalArticle

Open Access
Oral Hygiene
Head and Neck Neoplasms
Survival
Confidence Intervals
Tooth
1 Citation (Scopus)
Neoadjuvant Therapy
Squamous Cell Carcinoma
Clinical Trials
Staining and Labeling
Neoplasms
Head and Neck Neoplasms
Alcohol Drinking
Ethanol
Survival
Genes

TNF-α-induced miR-450a mediates TMEM182 expression to promote oral squamous cell carcinoma motility

Hsing, E. W., Shiah, S. G., Peng, H. Y., Chen, Y. W., Chuu, C. P., Hsiao, J-R., Lyu, P. C. & Chang, J-Y., 2019 Mar 1, In : PloS one. 14, 3, e0213463.

Research output: Contribution to journalArticle

Open Access
squamous cell carcinoma
tumor necrosis factor-alpha
Cell Movement
Squamous Cell Carcinoma
mouth
Head and Neck Neoplasms
Alcohols
Surveys and Questionnaires
Alleles
Validation Studies
2018
1 Citation (Scopus)

Alpha-tubulin acetyltransferase/MEC-17 regulates cancer cell migration and invasion through epithelial–mesenchymal transition suppression and cell polarity disruption

Lee, C. C., Cheng, Y. C., Chang, C. Y., Lin, C. M. & Chang, J-Y., 2018 Dec 1, In : Scientific reports. 8, 1, 17477.

Research output: Contribution to journalArticle

Cell Polarity
Cell Movement
Tubulin
Pseudopodia
Acetylation

Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation

Weng, T. Y., Wu, H. F., Li, C. Y., Hung, Y. H., Chang, Y. W., Chen, Y. L., Hsu, H. P., Chen, Y. H., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2018 Dec 1, In : Scientific reports. 8, 1, 8216.

Research output: Contribution to journalArticle

Mutation
Neoplasms
B-Lymphocytes
Lung
Cytokines
2 Citations (Scopus)

Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

Tsai, I. T., Kuo, C. C., Liou, J. P. & Chang, J. Y., 2018 Mar 28, In : Journal of biomedical science. 25, 1, 28.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Phosphorylation
Epithelial-Mesenchymal Transition
Transforming Growth Factors
Microtubules
4 Citations (Scopus)
Microbiota
Genetic Polymorphisms
Life Style
Squamous Cell Carcinoma
Oral Hygiene
Ubiquitin-Conjugating Enzymes
Carmustine
Ubiquitination
Methyltransferases
Cells
2017
3 Citations (Scopus)

Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways

Su, W-P., Ho, Y. C., Wu, C. K., Hsu, S. H., Shiu, J. L., Huang, J. C., Chang, S-B., Chiu, W-T., Hung, J-J., Liu, T., Wu, W-S., Wu, P. Y., Su, W-C., Chang, J-Y. & Liaw, H-J., 2017 Dec 1, In : Scientific reports. 7, 1, 3879.

Research output: Contribution to journalArticle

Fanconi Anemia
Recombinational DNA Repair
Cisplatin
Fanconi Anemia Complementation Group D2 Protein
Genes
2 Citations (Scopus)

Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells

Chen, H. H., Chang, H. H., Chang, J-Y., Tang, Y. C., Cheng, Y. C., Lin, L. M., Cheng, S. Y., Huang, C. H., Sun, M. W., Chen, C. T. & Kuo, C. C., 2017 Dec 1, In : Free Radical Biology and Medicine. 113, p. 505-518 14 p.

Research output: Contribution to journalArticle

KB Cells
Acetylation
Type II DNA Topoisomerase
Poisons
Transcription
1 Citation (Scopus)

Epidermal growth factor–induced pyruvate dehydrogenase kinase 1 expression enhances head and neck squamous cell carcinoma metastasis via up-regulation of fibronectin

Hsu, J. Y., Chang, J-Y., Chang, K. Y., Chang, W. C. & Chen, B-K., 2017 Oct 1, In : FASEB Journal. 31, 10, p. 4265-4276 12 p.

Research output: Contribution to journalArticle

Fibronectins
Matrix Metalloproteinases
Up-Regulation
Neoplasm Metastasis
Epidermal Growth Factor
17 Citations (Scopus)

Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness

Hou, P. C., Li, Y. H., Lin, S-C., Lin, S-C., Lee, J-C., Lin, P-W., Liou, J. P., Chang, J-Y., Kuo, C. C., Liu, Y. M., Sun, H-F. & Tsai, S-J., 2017 Aug 15, In : Cancer Research. 77, 16, p. 4305-4316 12 p.

Research output: Contribution to journalArticle

Dual-Specificity Phosphatases
Dual Specificity Phosphatase 2
Colonic Neoplasms
Down-Regulation
Neoplasms
10 Citations (Scopus)

Investigating the Association between Alcohol and Risk of Head and Neck Cancer in Taiwan

Huang, C-C., Hsiao, J-R., Lee, W-T., Lee, Y-C., Ou, C-Y., Chang, C-C., Lu, Y. C., Huang, J-S., Wang, D-Y., Chen, K-C., Tsai, S-T., Fang, S-Y., Wu, J-L., Wu, Y-H., Hsueh, W-T., Yen, C-J., Wu, S-Y., Chang, J-Y., Lin, C. L., Wang, Y. H. & 4 others, Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Dec 1, In : Scientific reports. 7, 1, 9701.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Taiwan
Alcohols
Hypopharyngeal Neoplasms
Oropharyngeal Neoplasms
4 Citations (Scopus)

Investigating the association between diet and risk of head and neck cancer in Taiwan

Chang, C-C., Lee, W-T., Lee, Y-C., Huang, C-C., Ou, C-Y., Lin, Y. H., Huang, J-S., Wang, D-Y., Chen, K-C., Hsiao, J-R., Lu, Y. C., Tsai, S-T., Lai, Y-H., Wu, Y-H., Hsueh, W-T., Yen, C-J., Wu, S-Y., Chang, J-Y., Fang, S-Y., Wu, J-L. & 5 others, Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Jan 1, In : Oncotarget. 8, 58, p. 98865-98875 11 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Taiwan
Vegetables
Diet
Fruit
5 Citations (Scopus)

Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy

Chen, Y. F., Chen, L. H., Yeh, Y-M., Wu, P-Y., Chen, Y. F., Chang, L. Y., Chang, J-Y. & Shen, M-R., 2017 Mar 28, In : Scientific reports. 7, 45366.

Research output: Contribution to journalArticle

Minoxidil
Neuroprotective Agents
Peripheral Nervous System Diseases
Paclitaxel
Hair
7 Citations (Scopus)

Parathyroid Hormone-Like Hormone is a Poor Prognosis Marker of Head and Neck Cancer and Promotes Cell Growth via RUNX2 Regulation

Chang, W. M., Lin, Y. F., Su, C. Y., Peng, H. Y., Chang, Y. C., Hsiao, J. R., Chen, C. L., Chang, J. Y., Shieh, Y. S., Hsiao, M. & Shiah, S. G., 2017 Jan 25, In : Scientific reports. 7, 41131.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Parathyroid Hormone
Hormones
Growth
Calcium

Pharmacokinetics and protein binding of MPT0B292

Tien, Y. E., Li, C. J., Liou, J. P., Chang, J-Y. & Huang, J. D., 2017 Jul 1, In : Biopharmaceutics and Drug Disposition. 38, 5, p. 340-350 11 p.

Research output: Contribution to journalArticle

Protein Binding
Pharmacokinetics
Albumins
Pharmaceutical Preparations
Nanoparticles

Regular recreational physical activity and risk of head and neck cancer

Lin, C. L., Lee, W-T., Ou, C-Y., Hsiao, J-R., Huang, C-C., Huang, J-S., Wang, D-Y., Chen, K-C., Tsai, S-T., Fang, S-Y., Huang, T-T., Wu, J-L., Wu, Y-H., Hsueh, W-T., Yen, C-J., Lai, Y-H., Liao, H. C., Wu, S-Y., Yang, M-W., Lin, F-C. & 6 others, Chang, J-Y., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Apr 21, In : BMC cancer. 17, 1, 286.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Tobacco Products
Vegetables
Fruit
Logistic Models

Skin Delivery of Clec4a Small Hairpin RNA Elicited an Effective Antitumor Response by Enhancing CD8+ Immunity In Vivo

Weng, T. Y., Li, C. J., Li, C. Y., Hung, Y. H., Yen, M. C., Chang, Y. W., Chen, Y-H., Chen, Y. L., Hsu, H-P., Chang, J-Y. & Lai, M-D., 2017 Dec 1, In : Molecular Therapy - Nucleic Acids. 9, p. 419-427 9 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Immunity
Skin
Neoplasms
DNA Vaccines
2 Citations (Scopus)
Macrophage Colony-Stimulating Factor
Colony-Stimulating Factor Receptors
Immunity
Macrophages
Genes
24 Citations (Scopus)

Tumour cell-derived WNT5B modulates in vitro lymphangiogenesis via induction of partial endothelial-mesenchymal transition of lymphatic endothelial cells

Wang, S. H., Chang, J. S., Hsiao, J-R., Yen, Y. C., Jiang, S. S., Liu, S. H., Chen, Y. L., Shen, Y. Y., Chang, J-Y. & Chen, Y. W., 2017 Mar 1, In : Oncogene. 36, 11, p. 1503-1515 13 p.

Research output: Contribution to journalArticle

Lymphangiogenesis
Squamous Cell Carcinoma
Endothelial Cells
Neoplasm Metastasis
Lymph Nodes
2016
6 Citations (Scopus)

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J-Y., Liou, J. P. & Lee, H. Y., 2016 Jan 1, In : Organic and Biomolecular Chemistry. 14, 2, p. 716-723 8 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Dione
Tubulin
Antineoplastic Agents
Inhibitory Concentration 50
6 Citations (Scopus)

A comprehensive analysis on the association between tobacco-free betel quid and risk of head and neck cancer in Taiwanese men

Wu, Y-H., Yen, C-J., Hsiao, J-R., Ou, C-Y., Huang, J-S., Wang, D-Y., Tsai, S-T., Huang, C-C., Lee, W-T., Chen, K-C., Fang, S-Y., Wu, J-L., Hsueh, W-T., Lin, F-C., Yang, M-W., Chang, J-Y., Liao, H. C., Wu, S-Y., Lin, C. L., Wang, Y. H. & 4 others, Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2016 Oct 1, In : PLoS ONE. 11, 10, 0164937.

Research output: Contribution to journalArticle

betel
Tobacco
Head and Neck Neoplasms
Mastication
tobacco
2 Citations (Scopus)

Allergy symptoms, serum total immunoglobulin E, and risk of head and neck cancer

Liao, H. C., Wu, S-Y., Ou, C-Y., Hsiao, J-R., Huang, J-S., Tsai, S-T., Huang, C-C., Wang, D-Y., Lee, W-T., Chen, K-C., Fang, S-Y., Wu, J-L., Huang, T-T., Wu, Y-H., Hsueh, W-T., Yen, C-J., Yang, M-W., Lin, F-C., Lai, Y-H., Chang, J-Y. & 6 others, Lin, C. L., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2016 Sep 1, In : Cancer Causes and Control. 27, 9, p. 1105-1115 11 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Immunoglobulin E
Hypersensitivity
Serum
Odds Ratio
1 Citation (Scopus)

A phase i clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid and subsequent IL-2 treatment John T Kung

Liu, K. J., Chao, T. Y., Chang, J-Y., Cheng, A. L., Ch'Ang, H. J., Kao, W. Y., Wu, Y. C., Yu, W. L., Chung, T. R. & Whang-Peng, J., 2016 Aug 24, In : Journal of biomedical science. 23, 1, 64.

Research output: Contribution to journalArticle

Tetanus Toxoid
Carcinoembryonic Antigen
Immunotherapy
Dendritic Cells
Interleukin-2
6 Citations (Scopus)

Cathepsin S attenuates endosomal EGFR signalling: A mechanical rationale for the combination of cathepsin S and EGFR tyrosine kinase inhibitors

Huang, C. C., Lee, C. C., Lin, H. H. & Chang, J-Y., 2016 Jul 8, In : Scientific reports. 6, 29256.

Research output: Contribution to journalArticle

cathepsin S
Protein-Tyrosine Kinases
Endosomes
Epidermal Growth Factor
STAT3 Transcription Factor
4 Citations (Scopus)

Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo

Chen, S. J., Kuo, C. C., Pan, H. Y., Tsou, T. C., Yeh, S. C. & Chang, J-Y., 2016 Jan 1, In : Oncotarget. 7, 31, p. 49310-49321 12 p.

Research output: Contribution to journalArticle

oxaliplatin
Transferrin Receptors
Deferoxamine
Platinum
Uterine Cervical Neoplasms
7 Citations (Scopus)

Development of nanoliposomal irinotecan (nal-IRI, MM-398, PEP02) in the management of metastatic pancreatic cancer

Chiang, N. J., Chang, J-Y., Shan, Y-S. & Chen, L. T., 2016 Jul 2, In : Expert Opinion on Pharmacotherapy. 17, 10, p. 1413-1420 8 p.

Research output: Contribution to journalReview article

irinotecan
gemcitabine
Leucovorin
Pancreatic Neoplasms
Fluorouracil
14 Citations (Scopus)

Dysregulation of RUNX2/activin-A axis upon miR-376c downregulation promotes lymph node metastasis in head and neck squamous cell carcinoma

Chang, W. M., Lin, Y. F., Su, C. Y., Peng, H. Y., Chang, Y. C., Lai, T. C., Wu, G. H., Hsu, Y. M., Chi, L. H., Hsiao, J-R., Chen, C. L., Chang, J-Y., Shieh, Y. S., Hsiao, M. & Shiah, S. G., 2016 Dec 15, In : Cancer Research. 76, 24, p. 7140-7150 11 p.

Research output: Contribution to journalArticle

Down-Regulation
Lymph Nodes
Neoplasm Metastasis
3' Untranslated Regions
Head and Neck Neoplasms
Insulin-Like Growth Factor Binding Protein 3
Somatomedins
Integrins
Cell Movement
Squamous Cell Carcinoma
19 Citations (Scopus)

IL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma

Peng, H. Y., Jiang, S. S., Hsiao, J-R., Hsiao, M., Hsu, Y. M., Wu, G. H., Chang, W. M., Chang, J-Y., Jin, S. L. C. & Shiah, S. G., 2016 Jun 1, In : Molecular Oncology. 10, 6, p. 895-909 15 p.

Research output: Contribution to journalArticle

Interleukin-8
Squamous Cell Carcinoma
Suppressor of Cytokine Signaling Proteins
Cell Movement
Janus Kinases
7 Citations (Scopus)

Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma

Cheng, C. W., Hsiao, J-R., Fan, C. C., Lo, Y. K., Tzen, C. Y., Wu, L-W., Fang, W. Y., Cheng, A. J., Chen, C. H., Chang, I. S., Jiang, S. S., Chang, J-Y. & Lee, A. Y. L., 2016 May 1, In : Molecular Carcinogenesis. 55, 5, p. 499-513 15 p.

Research output: Contribution to journalArticle

Growth Differentiation Factor 10
Epithelial-Mesenchymal Transition
Squamous Cell Carcinoma
Drug Therapy
Transforming Growth Factors
17 Citations (Scopus)

MiR-520h is crucial for DAPK2 regulation and breast cancer progression

Su, C. M., Wang, M. Y., Hong, C. C., Chen, H. A., Su, Y. H., Wu, C. H., Huang, M. T., Chang, Y. W., Jiang, S. S., Sung, S. Y., Chang, J-Y., Chen, L. T., Chen, P-S. & Su, J. L., 2016 Mar 3, In : Oncogene. 35, 9, p. 1134-1142 9 p.

Research output: Contribution to journalArticle

Death-Associated Protein Kinases
MicroRNAs
Breast Neoplasms
Drug Resistance
3' Untranslated Regions
11 Citations (Scopus)

MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma

Peng, H. Y., Cheng, Y. C., Hsu, Y. M., Wu, G. H., Kuo, C. C., Liou, J. P., Chang, J-Y., Jin, S. L. C. & Shiah, S. G., 2016 Jul 1, In : PLoS ONE. 11, 7, e0158440.

Research output: Contribution to journalArticle

non-specific protein-tyrosine kinase
Janus Kinase 2
STAT3 Transcription Factor
squamous cell carcinoma
Microtubules
23 Citations (Scopus)

The Role of Wnt Signaling in Squamous Cell Carcinoma

Shiah, S. G., Shieh, Y. S. & Chang, J-Y., 2016 Feb 1, In : Journal of Dental Research. 95, 2, p. 129-134 6 p.

Research output: Contribution to journalReview article

Wnt Signaling Pathway
Squamous Cell Carcinoma
MicroRNAs
Catenins
Neoplasms
31 Citations (Scopus)

Up-regulation of miR-455-5p by the TGF-β–SMAD signalling axis promotes the proliferation of oral squamous cancer cells by targeting UBE2B

Cheng, C. M., Shiah, S. G., Huang, C. C., Hsiao, J-R. & Chang, J-Y., 2016 Sep 1, In : Journal of Pathology. 240, 1, p. 38-49 12 p.

Research output: Contribution to journalArticle

Ubiquitin-Conjugating Enzymes
Mouth Neoplasms
Transforming Growth Factors
Up-Regulation
Epithelial Cells

建立分析模組評估神經功能之方法

Shen, M-R., Chang, J-Y. & Sun, Y-T., 2016 Apr 1, Patent No. I548873

Research output: Patent

2015
62 Citations (Scopus)

A KRAS mutation status-stratified randomized phase II trial of gemcitabine and oxaliplatin alone or in combination with cetuximab in advanced biliary tract cancer

on behalf of the Taiwan Cooperative Oncology Group, 2015 May 1, In : Annals of Oncology. 26, 5, p. 943-949 7 p., mdv035.

Research output: Contribution to journalArticle

oxaliplatin
gemcitabine
Biliary Tract Neoplasms
Mutation
Exanthema
4 Citations (Scopus)

Alcohol drinking obliterates the inverse association between serum retinol and risk of head and neck cancer

Chen, K-C., Hsueh, W-T., Ou, C-Y., Huang, C-C., Lee, W-T., Fang, S-Y., Tsai, S-T., Huang, J-S., Wang, D-Y., Wu, J-L., Yen, C-J., Wu, Y-H., Lin, F-C., Yang, M-W., Chang, J-Y., Liao, H. C., Wu, S-Y., Hsiao, J-R., Lin, C. L., Wang, Y. H. & 4 others, Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2015 Jul 1, In : Medicine (United States). 94, 26, e1064.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Vitamin A
Alcohol Drinking
Serum
Alcohols
14 Citations (Scopus)

Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes

Lee, H. Y., Chang, C. Y., Lai, M. J., Chuang, H. Y., Kuo, C. C., Chang, C. Y., Chang, J-Y. & Liou, J. P., 2015 Jul 23, In : Bioorganic and Medicinal Chemistry. 23, 15, p. 4230-4236 7 p.

Research output: Contribution to journalArticle

Antimitotic Agents
KB Cells
Colchicine
Tubulin
Polymerization
16 Citations (Scopus)

Autophagy-regulated ROS from xanthine oxidase acts as an early effector for triggering late mitochondria-dependent apoptosis in cathepsin S-targeted tumor cells

Huang, C. C., Lee, C. C., Lin, H. H., Chen, M. C., Lin, C. C. & Chang, J-Y., 2015 Jun 1, In : PloS one. 10, 6, e0128045.

Research output: Contribution to journalArticle

cathepsin S
Mitochondria
xanthine oxidase
autophagy
Xanthine Oxidase
22 Citations (Scopus)

Changes in DNA methylation are associated with the development of drug resistance in cervical cancer cells

Chen, C. C., Lee, K. D., Pai, M. Y., Chu, P. Y., Hsu, C. C., Chiu, C. C., Chen, L. T., Chang, J-Y., Hsiao, S. H. & Leu, Y. W., 2015 Oct 13, In : Cancer Cell International. 15, 1, 98.

Research output: Contribution to journalArticle

DNA Methylation
Drug Resistance
Uterine Cervical Neoplasms
Methylation
oxaliplatin
1 Citation (Scopus)

Genetic polymorphisms in the prostaglandin pathway genes and risk of head and neck cancer

Lee, W-T., Huang, C-C., Chen, K-C., Wang, D-Y., Ou, C-Y., Tsai, S-T., Yen, C-J., Fang, S-Y., Lo, H. I., Wu, Y-H., Hsueh, W-T., Yang, M-W., Lin, F-C., Hsiao, J-R., Huang, J-S., Chang, J-Y., Chang, K. Y., Wu, S-Y., Lin, C. L., Wang, Y. H. & 3 others, Weng, Y. L., Yang, H. C. & Chang, JS. S., 2015 Mar 1, In : Oral Diseases. 21, 2, p. 207-215 9 p.

Research output: Contribution to journalArticle

Genetic Polymorphisms
Head and Neck Neoplasms
Prostaglandins
Genes
Odds Ratio