• 195 Citations
  • 9 h-Index
20062019
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Research Output 2006 2019

  • 195 Citations
  • 9 h-Index
  • 24 Article
  • 1 Editorial
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Article
2019
Open Access
Leucine-Responsive Regulatory Protein
Clostridium difficile
Genome
Gram-Positive Bacteria
Virulence Factors
2018
2 Citations (Scopus)

A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli

Kuo, C. J., Wang, S. T., Lin, C. M., Chiu, H. C., Huang, C. R., Lee, D. Y., Chang, G. D., Chou, T. C., Chen, J. W. & Chen, C. S., 2018 Mar 1, In : Cell Death and Disease. 9, 3, 381.

Research output: Contribution to journalArticle

Enterohemorrhagic Escherichia coli
Fumarates
Virulence
Caenorhabditis elegans
Escherichia coli Infections
1 Citation (Scopus)
Genomics
Plasmids
Clone Cells
Escherichia coli
Cefixime
7 Citations (Scopus)

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model

Yang, H. T., Chen, J. W., Rathod, J., Jiang, Y. Z., Tsai, P. J., Hung, Y. P., Ko, W. C., Paredes-Sabja, D. & Huang, I. H., 2018 Jan 17, In : Frontiers in Microbiology. 8, JAN, 2635.

Research output: Contribution to journalArticle

lauric acid
Clostridium difficile
Inflammation
Clostridium Infections
Growth
2017
Ribotyping
Clostridium difficile
Taiwan
Prophages
Genome
4 Citations (Scopus)
Clostridium difficile
Immunization
Clostridium Infections
Vaccines
Chitosan
2 Citations (Scopus)

Lrp, a global regulator, regulates the virulence of Vibrio vulnificus

Ho, Y. C., Hung, F. R., Weng, C. H., Li, W. T., Chuang, T. H., Liu, T. L., Lin, C. Y., Lo, C. J., Chen, C. L., Chen, J. W., Hashimoto, M. & Hor, L. I., 2017 Aug 11, In : Journal of biomedical science. 24, 1, 1 p.

Research output: Contribution to journalArticle

Vibrio vulnificus
Virulence
Genes
Chemotaxis
Cytotoxicity
3 Citations (Scopus)
Flagella
Helicobacter pylori
Genes
Sigma Factor
Glycosyltransferases
2016
5 Citations (Scopus)

Expression regulation of polycistronic lee3 genes of enterohaemorrhagic Escherichia coli

Sun, W. S. W., Chen, J. W., Wu, Y. C., Tsai, H. Y., Kuo, Y. L. & Syu, W. J., 2016 May, In : PloS one. 11, 5, e0155578.

Research output: Contribution to journalArticle

Enterohemorrhagic Escherichia coli
enterohemorrhagic Escherichia coli
Escherichia coli
Genes
translation (genetics)
5 Citations (Scopus)
Enterohemorrhagic Escherichia coli
Innate Immunity
Lipopolysaccharides
Mutation
Enzymes
1 Citation (Scopus)

Unique clustering genes in the bacterial chromosome affecting the type-III secretion of enterohaemorrhagic Escherichia coli

Lin, I. T., Chiou, Y. M., Liang, Y. C., Lin, C. N., Sun, W. S. W., Li, S., Chang, C. H., Syu, W. J. & Chen, J. W., 2016 Oct, In : Microbiology (United Kingdom). 162, 10, p. 1744-1754 11 p.

Research output: Contribution to journalArticle

Bacterial Chromosomes
Enterohemorrhagic Escherichia coli
Cluster Analysis
Genes
Enterocytes
2015
7 Citations (Scopus)

Comparative genomic and phenomic analysis of Clostridium difficile and Clostridium sordellii, two related pathogens with differing host tissue preference

Scaria, J., Suzuki, H., Ptak, C. P., Chen, J. W., Zhu, Y., Guo, X. K. & Chang, Y. F., 2015 Dec 12, In : BMC genomics. 16, 1, 448.

Research output: Contribution to journalArticle

Clostridium sordellii
Clostridium difficile
Clostridium Infections
Genome
Phenotype
1 Citation (Scopus)

Genome Sequence and Annotation of Helicobacter pylori Strain Hp238, Isolated from a Taiwanese Patient with Mucosa-Associated Lymphoid Tissue Lymphoma

Kao, C. Y. C. Y., Chen, J-W., Huang, Y. T., Sheu, S. M. S. M., Sheu, B-S. & Wua, J. J., 2015 Jan 1, In : Genome Announcements. 3, 1, e00006-15.

Research output: Contribution to journalArticle

Marginal Zone B-Cell Lymphoma
Helicobacter pylori
Genome
Gastric Mucosa
Genes
2014
8 Citations (Scopus)

Comparative nutritional and chemical phenome of Clostridium difficile isolates determined using phenotype microarrays

Scaria, J., Chen, J. W., Useh, N., He, H., McDonough, S. P., Mao, C., Sobral, B. & Chang, Y. F., 2014 Oct 1, In : International Journal of Infectious Diseases. 27, p. 20-25 6 p.

Research output: Contribution to journalArticle

Clostridium difficile
Phenotype
Clostridium Infections
Food
Enteral Nutrition
2013
9 Citations (Scopus)

Differential stress transcriptome landscape of historic and recently emerged hypervirulent strains of Clostridium difficile strains determined using RNA-seq

Scaria, J., Mao, C., Chen, J. W., McDonough, S. P., Sobral, B. & Chang, Y. F., 2013 Nov 7, In : PloS one. 8, 11, e78489.

Research output: Contribution to journalArticle

Clostridium difficile
Clostridium
Transcriptome
transcriptome
Genes
16 Citations (Scopus)

Evaluation of a mycobacterium avium subsp. paratuberculosis leuD mutant as a vaccine candidate against challenge in a caprine model

Faisal, S. M., Chen, J. W., Yan, F., Chen, T. T., Useh, N. M., Yan, W., Guo, S., Wang, S. J., Glaser, A. L., McDonough, S. P., Singh, B., Davis, W. C., Akey, B. L. & Chang, Y. F., 2013 Apr 1, In : Clinical and Vaccine Immunology. 20, 4, p. 572-581 10 p.

Research output: Contribution to journalArticle

Paratuberculosis
Interleukin-23
Mycobacterium avium
Interferons
Vaccines
20 Citations (Scopus)

Proteomic comparison of historic and recently emerged hypervirulent clostridium difficile strains

Chen, J. W., Scaria, J., Mao, C., Sobral, B., Zhang, S., Lawley, T. & Chang, Y. F., 2013 Mar 11, In : Journal of Proteome Research. 12, 3, p. 1151-1161 11 p.

Research output: Contribution to journalArticle

Clostridium
Clostridium difficile
Osmotic Pressure
Proteomics
Pathogens
2012
7 Citations (Scopus)

Immune response and protective efficacy of live attenuated Salmonella vaccine expressing antigens of Mycobacterium avium subsp. paratuberculosis against challenge in mice

Chandra, S., Faisal, S. M., Chen, J. W., Chen, T. T., McDonough, S. P., Liu, S., Moreira, M. A. S., Akey, B. L., Chang, C. F. & Chang, Y. F., 2012 Dec 17, In : Vaccine. 31, 1, p. 242-251 10 p.

Research output: Contribution to journalArticle

Salmonella Vaccines
Paratuberculosis
Mycobacterium avium
Attenuated Vaccines
Mycobacterium avium subsp. paratuberculosis
12 Citations (Scopus)

Immunogenicity and protective efficacy of the Mycobacterium avium subsp. paratuberculosis attenuated mutants against challenge in a mouse model

Chen, J-W., Faisal, S. M., Chandra, S., McDonough, S. P., Moreira, M. A. S., Scaria, J., Chang, C. F., Bannantine, J. P., Akey, B. & Chang, Y. F., 2012 Apr 19, In : Vaccine. 30, 19, p. 3015-3025 11 p.

Research output: Contribution to journalArticle

Paratuberculosis
Mycobacterium avium
Mycobacterium avium subsp. paratuberculosis
Vaccines
animal models
12 Citations (Scopus)

Phenotypic and transcriptomic response of auxotrophic mycobacterium avium subsp. paratuberculosis leuD mutant under environmental stress

Chen, J. W., Scaria, J. & Chang, Y. F., 2012 Jun 4, In : PloS one. 7, 6, e37884.

Research output: Contribution to journalArticle

Paratuberculosis
Mycobacterium avium
Mycobacterium avium subsp. paratuberculosis
transcriptomics
Genes
2011
12 Citations (Scopus)

Immunostimulatory and antigen delivery properties of liposomes made up of total polar lipids from non-pathogenic bacteria leads to efficient induction of both innate and adaptive immune responses

Faisal, S. M., Chen, J. W., McDonough, S. P., Chang, C. F., Teng, C. H. & Chang, Y. F., 2011 Mar 16, In : Vaccine. 29, 13, p. 2381-2391 11 p.

Research output: Contribution to journalArticle

antigen-presenting cells
Adaptive Immunity
Antigen-Presenting Cells
Innate Immunity
Liposomes
2010
17 Citations (Scopus)

A role of ygfZ in the Escherichia coli response to plumbagin challenge

Lin, C. N., Syu, W. J., Sun, W. S. W., Chen, J. W., Chen, T. H., Don, M. J. & Wang, S. H., 2010 Nov 11, In : Journal of biomedical science. 17, 1, 84.

Research output: Contribution to journalArticle

Escherichia coli
Bacteria
plumbagin
Genes
Mutagenesis
2006
20 Citations (Scopus)

Expression analysis of up-regulated genes responding to plumbagin in Escherichia coli

Chen, J. W., Sun, C. M., Sheng, W. L., Wang, Y. C. & Syu, W., 2006 Jan 1, In : Journal of Bacteriology. 188, 2, p. 456-463 8 p.

Research output: Contribution to journalArticle

Escherichia coli
Genes
Sodium Salicylate
Mars
Bacterial Genes
22 Citations (Scopus)

Multiple functions of l0036 in the regulation of the pathogenicity island of enterohaemorrhagic Escherichia coli O157:H7

Tsai, N. P., Wu, Y. C., Chen, J. W., Wu, C. F., Tzeng, C. M. & Syu, W., 2006 Jan 15, In : Biochemical Journal. 393, 2, p. 591-599 9 p.

Research output: Contribution to journalArticle

Enterohemorrhagic Escherichia coli
Genomic Islands
Escherichia coli O157
Enterocytes
Escherichia coli