Projects per year
Personal profile
Education
- 1999 PhD, National Defense Medical Center, Institute of Life Sciences
Research Interests
- gene transcription
- Molecular cancer
- Molecular inflammation
- signal transduction
Experience
- 2017.08~now Professor, Department of Biotechnology and Bioindustry Sciences, NCKU, TW
- 2016.08~now Distinguished Professor, NCKU, TW
- 2015.02~now Associate Vice President of Academic Affairs, NCKU, TW
- 2015.02~now Director of Center for Faculty Development, NCKU, TW
- 2013.01~now Adjunct Professor, Graduate Institute of Medical Sciences, TMU, TW
- 2012.09~now Adjunct Professor, Institute of Pharmacology, NCKU, TW
- 2012.09~now Adjunct Professor, Institute of Basic Medical Sciences, NCKU, TW
- 2018.06-2018.08 Visiting Research Scholar, Ins. of Molecular and Cellular Oncology, MD Anderson, USA
- 2015.02~2017.12 Director of Yunlin Chiayi and Tainan Regional Teaching Resource Center, NCKU, TW
- 2013.08~2016.07 Director of Institute of Bioinformatics and Biosignal Transduction, NCKU, TW
- 2013.07~2013.09 Visiting Research Scholar, Department of Pharmacology, Kyoto University, JP
- 2012.09~2017.07 Professor, Institute of Bioinformatics and Biosignal Transduction, NCKU, TW
- 2012.07~2012.09 Visiting Research Scholar, Department of Pharmacology, Kyoto University, JP
- 2011.07~2011.09 Visiting Research Scholar, Department of Biological Chemistry, UC Irvine, USA
- 2009.09~2012.08 Associate Professor, Institute of Bioinformatics and Biosignal Transduction, NCKU, TW
- 2009.09~2012.08 Adjunct Associate Professor, Institute of Basic Medical Sciences, NCKU, TW
- 2009.09~2012.08 Adjunct Associate Professor, Institute of Pharmacology, NCKU, TW
- 2008.03~2009.08 Adjunct Assistant Professor, Institute of Basic Medical Sciences, NCKU, TW
- 2007.09~2010.08 Adjunct Assistant Professor, Institute of Bioinformatics, NCKU, TW
- 2006.09~2009.08 Assistant Professor, Institute of Biosignal Transduction, NCKU, TW
- 2006.09~2009.08 Adjunct Assistant Professor, Institute of Pharmacology, NCKU, TW
- 2005.03~2006.08 Postdoctoral, Institute of Biological Chemistry, UC Irvine, USA
- 2004.11~2005.02 Research Assistant Professor, Institute of Pharmacology, NCKU, TW
- 2003.02~2004.10 Postdoctoral, Institute of Pharmacology, NCKU, TW
- 2000.01~2003.01 Postdoctoral, Institute of Molecular Biology, Academia Sinica, TW
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Projects
- 19 Finished
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多型性膠質母細胞瘤內CCAAT/enhancer binding protein delta影響癌周邊環境及其之於temozolomide抗藥性的功能探討
19-08-01 → 20-07-31
Project: Research project
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分析及評估新穎發炎標的蛋白在晚期與抗藥性肝癌的癌化過程及治療應用之研究-探討CEBPD/PTX3 路徑角色及開發PTX3標靶應用於抗藥性肝癌的治療(1/3)
19-08-01 → 20-07-31
Project: Research project
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多型性膠質母細胞瘤內CCAAT/enhancer binding protein delta影響癌周邊環境及其之於temozolomide抗藥性的功能探討
17-08-01 → 18-07-31
Project: Research project
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探討星狀膠細胞內RNF112 與mir135a 受到轉錄因子CEBPD 誘發之分子機制及其在阿茲海默症中的生理角色扮演(3/3)
16-08-01 → 17-07-31
Project: Research project
Research output
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Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation
Lai, H. Y., Tsai, H. H., Yen, C. J., Hung, L. Y., Yang, C. C., Ho, C. H., Liang, H. Y., Chen, F. W., Li, C. F. & Wang, J-M., 2021 Jan 21, In: Frontiers in Cell and Developmental Biology. 8, 596655.Research output: Contribution to journal › Article › peer-review
Open Access -
CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity
Chen, R. Y., Yen, C. J., Liu, Y. W., Guo, C. G., Weng, C. Y., Lai, C. H., Wang, J. M., Lin, Y. J. & Hung, L. Y., 2020 Apr 1, In: Cell Death and Differentiation. 27, 4, p. 1259-1273 15 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis
Yen, C. J., Yang, S. T., Chen, R. Y., Huang, W., Chayama, K., Lee, M. H., Yang, S. J., Lai, H. S., Yen, H. Y., Hsiao, Y. W., Wang, J. M., Lin, Y. J. & Hung, L. Y., 2019 Jun 6, In: Journal of biomedical science. 26, 1, 44.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Hepatoma-derived growth factor supports the antiapoptosis and profibrosis of pancreatic stellate cells
Chen, Y. T., Chen, F. W., Chang, T. H., Wang, T. W., Hsu, T. P., Chi, J. Y., Hsiao, Y. W., Li, C. F. & Wang, J. M., 2019 Aug 10, In: Cancer Letters. 457, p. 180-190 11 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation
Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, Y-M., 2018 Jun, In: Redox Biology. 16, p. 104-112 9 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)